CLUSTAL W (1.83) multiple sequence alignment TRKC_Hsap IVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL-AARKDFQREAELLTNLQ TRKB_Hsap IVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASD-NARKDFHREAELLTNLQ TRKA_Hsap IVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASE-SARQDFQREAELLTMLQ D1073.1_Cele ---------------------------------------------MKTFKVTARVLQDLE TRKA_Mmus IILKWELGEGAFGKVFLAECYNLLNDQDKMLVAVKALKEASE-NARQDFQREAELLTMLQ TRKB_Mmus IVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASD-NARKDFHREAELLTNLQ TRKC_Mmus IVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTL-AARKDFQREAELLTNLQ Trk_Spur IRFIGELGEGAFGVVCLGQCEHLPGADGPTMVAIKTLKDASVGDARTDFEREAELLTNLQ *. *.:* *: TRKC_Hsap HEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM TRKB_Hsap HEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNP---PTELTQSQM TRKA_Hsap HQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED-VAPGPLGLGQL D1073.1_Cele HPNIVKLYGMTRNNFNLLLVFEHMNHGDLKTYLEQRAPVKSVYLQY-----PPPLVIDEL TRKA_Mmus HQHIVRFFGVCTEGGPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGED-VAPGPLGLGQL TRKB_Mmus HEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNP---PTELTQSQM TRKC_Mmus HEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQM Trk_Spur HKNIVAFYGVCTDHEPFFMVFEYMENGDLNNYLKSRGPDADCFTRNQA---LLPLTVKEL * :** ::*: : :::***:*.:***: :*. :.* * :: TRKC_Hsap LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYS-TDYYRLFNP TRKB_Hsap LHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYS-TDYYR---- TRKA_Hsap LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS-TDYYR---- D1073.1_Cele KWIIKEITTGLVYLVEQSIVHRDLAARNCLVAGDSDLxISDFGMSRRLYDHSEYYT---- TRKA_Mmus LAVASQVAAGMVYLASLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYS-TDYYR---- TRKB_Mmus LHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYS-TDYYR---- TRKC_Mmus LHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYS-TDYYRLFNP Trk_Spur LYIAKQIASGMVYMASQHFVHRDMATRNCLVGDRLIVKIADFGMSRDVYS-TDYYR---- : .::::*:**:. :****:*:*****. : *.****** :*. ::** TRKC_Hsap SGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLS TRKB_Hsap ----------VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLS TRKA_Hsap ----------VGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS D1073.1_Cele ----------MDHRGALPVRWLPPEAVQSHKFTYNSDIWSLGVTMWECMSYGRQPFDGLS TRKA_Mmus ----------VGGRTMLPIRWMPPESILYRKFSTESDVWSFGVVLWEIFTYGKQPWYQLS TRKB_Mmus ----------VGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLS TRKC_Mmus SGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLS Trk_Spur ----------VGGHTMLPVRWMPPESIIYRTYSVESDVWSYGVVLWEIFEYGKQPWFGLS :. : **:**:***:: :.:: :**:** ** :** : **:**: ** TRKC_Hsap NTEVIECITQGRVL-ERPRVCPKEVYDVMLGCWQREPQQRLNIKEIY----KI TRKB_Hsap NNEVIECITQGRVL-QRPRTCPQEVYELMLGCWQREPHMRKNIKGIHT---LL TRKA_Hsap NTEAIDCITQGREL-ERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQAL D1073.1_Cele NLEVSSFTLAGKhrplKPERCPQDMYDLMVKCWHMEPVKRITAKQ-------I TRKA_Mmus NTEAIECITQGREL-ERPRACPPDVYAIMRGCWQREPQQRLSMKDVHARLQAL TRKB_Mmus NNEVIECITQGRVL-QRPRTCPQEVYELMLGCWQREPHTRKNIKSIHT---LL TRKC_Mmus NTEVIECITQGRVL-ERPRVCPKEVYDVMLGCWQREPQQRLNIKEIY----KI Trk_Spur NHEVIEYIHNGILL-DCPKGCPKEVYKIMLGSWQRQPTQRMLIKDLHD---AI * *. . * *. ** ::* :* .*: :* * * :