Gene LRR8_y-2 (S.moellendorffii)

LRR8_y-2

Species: S.moellendorffii
Alias: LRR8_y-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8

Sequence

Name Sequence Type Origin Length Description Download
LRR8_y-2.AA Protein None 546 None Fasta, JSON
LRR8_y-2.NA RNA None 1641 None Fasta, JSON
LRR8_y-2.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of LRR8_y-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF26 LRR8_y-2.AA DUF26 94-139 22 1.9e-07 24.6 Pfam 12-55 (55) Show / Hide 
Range on Protein: 94-139
Range on HMM: 12-55/55
Sequence Identity: 22% (11 aa)

DQTSCASCIQQTYSEF-QQLAPLAVGGVLWTNDTSNRCRIRFENYN-F
. ..|..|...  ... .|. | ..||. |    . .| .|...|. |
SPSDCRDCLATAVRQMLPQCCPNRQGGRIW----YDWCYLRYSDYPNF
Kinase LRR8_y-2.AA TKL 259-525 20 8.2e-66 224.95 In-house 1-364 (364) Show / Hide 
Range on Protein: 259-525
Range on HMM: 1-364/364
Sequence Identity: 20% (77 aa)

LGQGGFGTVYKATLNN---------GSQVAVKKLSLQSNQGK---------------------------REFVNEITIITGIQHRNLVRLKGYCVEADE-
.|.||||.|||.....         |  |||||.. .... .                            ....|| ..  ..| |.|...||| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFLNKGS-LDRALFSSGSNAFLDWQSRFQIAIGIARGLGYLHEESH-----VQVIHRDIKASNILLDDKLQ------------
              .|.|.  .|| |.. .          |. |...|..||||. ||| .        ..||||.| .|||.|....            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PKISDFGISKLFDLDKGFGVTSTK----------------VAGTLGYMAPEYAT----------------RGRLTAKADVFSYGILVLEIASGRKCVD
  .||.|||.|. .. ...   |.|.                . ||...||||                    .  . |.||.|.||.  ||.....   
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

PAL-PAEEELLLQ----LSWKLVMANRMSECIDKRLGG----DYAVEEVSRLLRVAMLCTQEHEEARPTMSDVVAML
|   . ... ..|    . ...|  ...   |. .               .. . .. | ..  |.||......  |
PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR8_y-2.AA IRAK 253-457 35 2.8e-64 219.86 In-house 1-225 (317) Show / Hide 
Range on Protein: 253-457
Range on HMM: 1-225/317
Sequence Identity: 35% (81 aa)

FSERNKLGQGGFGTVYKATLNNGS-QVAVKKL----SLQSNQGKREFVN---EITIITGIQHRNLVRLKGYCVEADERLLVYEFLNKGSLDRALFSSG-S
|.. |..|.||||.||.. ..|    .|||||    ... |. ...|     |. . . ..| |.| | ||| | ..  |||...  |||   |   . .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

NAF--LDWQSRFQIAIGIARGLGYLHEES-HVQVIHRDIKASNILLDDKLQPKISDFGISKLF----DLDKGFG---VTSTKVAGTLGYMAPEYAT--RG
..   | |. |. |..|.|.|...||. .  . .||.||| .|||||. ..|||.|||         .. |.      ||. | ||. ||.||. .   |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSH-VRGTTWYMPPEFIRDPQG

RLTAKADVFSYGILVLEIASGRKCVD
.|| | ||.| || .||...|.. |.
QLTKKTDVYSFGIVLLEVLTGCRAVY
Kinase LRR8_y-2.AA Pkinase 253-453 29 5e-48 170.68 Pfam 1-209 (293) Show / Hide 
Range on Protein: 253-453
Range on HMM: 1-209/293
Sequence Identity: 29% (64 aa)

FSERNKLGQGGFGTVYKATLNNGSQ-VAVKKLSLQSNQG--KREFVN--EITIITGIQHRNLVRLKGYCVEADERLLVYEFLNKG----SLDRALF--SS
.    |.|.|.||.|||..  . .. ||||.......    ... ..  || |   ..| | |||.... . |.  .| |....|    .| . .   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSNAFLDWQSRFQIAIGIARGLGYLHEESHVQVIHRDIKASNILLDDKLQP----KISDFGISKLFDLDKGFGVTSTKVAGTLGYMAPEYAT-RGRLTAK
|.   ....    ..  |.||| |.|..    .||||.| .|||.|.. ..    ||.|||..|.||     ..  | ..||..|||||    .   . |
GCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

ADVFSYGILVLEIASGR
.|..|.|... | ..||
VDMWSCGCILYEMLCGR
Kinase LRR8_y-2.AA TKL-Unique 257-452 33 3e-43 150.01 In-house 3-224 (290) Show / Hide 
Range on Protein: 257-452
Range on HMM: 3-224/290
Sequence Identity: 33% (74 aa)

NKLGQGGFGTVYKATLNNGSQVAVKKLSL---QSNQGKREFVNEITIITGIQ-HRNLVRLKGYCV----EADERLLVYEFLNKGSLDRALF----SS---
||.|.||.|.|||..  .|..||.|....   .||. ..|| ||....  .. | |.|.. |||.     . .. .| |... |||.  |      .   
NKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

GSNAFLDWQSRFQIAIGIARGLGYLHEESHVQVIHRDIKASNILLDDK-----LQPKISDFGISKLFD-LDKGFGVTS-----TKVAGTLGYMAPEYATR
 .|  |..| | ..|| ||.|. ||| ..   .||||.| ||.|.| .     .. ||.|||.||. .  .|..  ..     . . |.. .||||  ..
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GRLTAKADVFSYGILVLEIASG
     . |.||.|.|| . |||..
NFCQYSEKSDVYSFGIVLWEIATR
Kinase LRR8_y-2.AA Dicty4 253-450 32 1.1e-41 136.92 In-house 1-211 (277) Show / Hide 
Range on Protein: 253-450
Range on HMM: 1-211/277
Sequence Identity: 32% (69 aa)

FSERNKLGQGGFGTVYKATLNNGSQVAVKKL-SLQSN-QGKR--EFVNEITIITGIQHRNLVRLKGYCV----EADERLLVYEFLNKGSLDRALFS----
    ...|.|.||.|||.|   |..|||||| ... |   ..  || .|..|   |.| |.. ..|.|     .  . . | |.. ||.| . | .    
INIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

SGSNAFLDWQSRFQ---IAIGIARGLGYLHEESHVQVIHRDIKASNILLDDKLQPKISDFGISKLFDLDKGFGV-TSTKVAGTLGYMAPEYATRGRLTAK
  ..  |||  . .   .|. .|||. .||. . . .||||.|..|.| |. .. |..|||.|...  .. ..  ..| ..|| ..||||     . . |
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMT-ACGTPCWMAPEVMMHQPYNEK

ADVFSYGILVLEIA
|||.|.||.  ||.
ADVYSFGIVLWEIL
Kinase LRR8_y-2.AA MLK 253-453 25 2.2e-41 141.33 In-house 1-233 (291) Show / Hide 
Range on Protein: 253-453
Range on HMM: 1-233/291
Sequence Identity: 25% (61 aa)

FSERNKLGQGGFGTVYKATLNNGS----QVAVKKLSL------QSNQGKREFVNEITIITGIQHRN----LVRLKGYCVEADE-RLLVYEFLNKGSLDRA
. .  ..| |.|| |.|..  |       ||||.         ..   ...|  |. .   ..|.|     ....| | .     ..| |.. .||| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LFSSGSNAF-----------LDWQSRFQIAIGIARGLGYLHEESHVQVIHRDIKASNILLDD------KLQPKISDFGISKLFDLDKGFGVTSTKVAGTL
| .  |. .            | .. ...|  .|||. |||..  ...||||.| .|||.|.      ... ||.|||.|  .|. .    . .. |||.
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS--RDWHQMC-TNMMSNAGTY

GYMAPEY---ATRGRLTAKADVFSYGILVLEIASGR
 .||||    .  .. . |.||.|.|..  |. ...
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase LRR8_y-2.AA STE 253-453 22 1.1e-39 137.85 In-house 1-265 (359) Show / Hide 
Range on Protein: 253-453
Range on HMM: 1-265/359
Sequence Identity: 22% (63 aa)

FSERNKLGQGGFGTVYKATLNN----------------GSQVAVKKLSLQSNQG-----------------KREFVNEITIITGIQ--HRNLVRLKGYCV
.    |.|.|.|||||||  ..                |  .|.|...|....                  . .. .|| |    .  | | |.  |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EA-------DERLLVYEFLNKGSLDRALF---SSGSN--------AFLDWQSRFQIAIGIARG-LGYLHEESHVQVIHRDIKASNILLDDKLQPKISDFG
         ||  .. |... ||||  .    . | .         ... .    |.  | .| | |||.     .||||||..||||      |..|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

ISKLFDLDKG-------------FGVTSTKVAGTLGYMAPEYATRGR------LTAKADVFSYGILVLEIASGR
... .. .                .  .. ..||  .||||  ....       ..|.|. | |....| | |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LRR8_y-2.AA TK 253-451 16 1.5e-39 129.73 In-house 1-389 (486) Show / Hide 
Range on Protein: 253-451
Range on HMM: 1-389/486
Sequence Identity: 16% (64 aa)

FSERNKLGQGGFG---TVYKATLNNGS--------------------------QVAVKKLSLQSNQGKRE-----------------FVNEITIITG--I
    .|||.| ||   .|||.......                          .|||| | . ... ..|                 ...|. .      
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHRNLVRLKGYCVEADE------------RLLVYEFLNKGS----LDRALFSSGS---------------------------------------------
.| |.||| |.|.. ..             ..| |. ..|.    |.  | ..                                               
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------------------------NAFLDWQSRFQIAIGIARGLGYLHEE--SHV--QVIHRDIKASNILLDDKLQ-----------PKISDFGIS
                            ...|. . .  ..  ||.|. |||.   .    ...|||. | |.|......            ||.||| |
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------KLFDLDKGFGVTSTKVAGTLG-------------------------YMAPEYAT---------RGRLTAKADVFSYGILVLEIAS
         |....   ....  || .                         .||||  .          |. | | ||.|.|.|. || .
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase LRR8_y-2.AA TyrKc 253-525 25 4.7e-37 130.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 253-525
Range on HMM: 1-280/280
Sequence Identity: 25% (78 aa)

FSERNKLGQGGFGTVYKATLNNGSQVAVKKLSLQSNQGKREFVNEITIITGI--QHRNLVRLKGYCVEA-------DERLLVYEFLNKGSLDRALFSSGS
 .   ||| | ||.|||.|..   |||||.|   .   ...| .|. | . .  .| |.||| |.|..        .  ..| |.  .|.|.  | ... 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

NAFLDWQSRFQIAIGIARGLGYLHEESHVQVIHRDIKASNILLDDKLQPKISDFGISKLFDLD-------KGFGVT---STKVAGTLGYMAPEYATRGRL
.  | ..   .... ||.|  |||.    ..||||. | |.|...... |||||| |.  . |       .   ..   ..|    .  ||||    |. 
K--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TAKADVFSYGILVLEIASGRKCVDPALPAEEE----LLLQLSWKLVMANRMSECIDK-----RLGGDYAVEEVSRLLRVAMLCTQEHEEARPTMSDVVAM
| | ||.|.|..  || .     . . | ...    .  |   ..|.. .. .. .             |.  . . ..   | .|  | |||.|...  
TTKSDVWSFGVCMWEIFT-----YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF------VCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase LRR8_y-2.AA S_TKc 253-532 24 8e-37 129.58 SMART 1-231 (231) Show / Hide 
Range on Protein: 253-532
Range on HMM: 1-231/231
Sequence Identity: 24% (70 aa)

FSERNKLGQGGFGTVYKATLNN-GSQVAVKKLSLQSNQGKREFVNEITIITGIQHRNLVRLKGYCVEADERLLVYEFLNK--GSLDRALFSSGSNA----
.   .|.|.|.||.|||.. .. | .||.|...       . . .|| |    .| |.|.|...... |.  .| |...   |.| . . . |..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FLDWQSRFQIAIGIARGLGYLHEESHVQVIHRDIKASNILLDDKLQPKISDFGISKLFDLDKGFGVTSTKVAGTLGYMAPEYATRGRLTA-KADVFSYGI
|   . || ..  |...| |.|  || ..||||.| .|||||.  . ||.|||.....          | . ||. |||||       .  |.|. | |.
FPE-HARF-YMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LVLEIASGRKCVDPALPAEEELLLQLSWKLVMANRMSECIDKRLGGDYAVEEVSRLLRVAMLCTQEHEEARPTMSDVVA--MLLGSHSSS
.. | ..|.   .     ........                           . ..   . | |   | |||  .. .  ..  .|   
ILYEMLCGYPPFP-----QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR8_y-2.AA LRRK 253-453 24 1.6e-36 126.76 In-house 1-279 (351) Show / Hide 
Range on Protein: 253-453
Range on HMM: 1-279/351
Sequence Identity: 24% (71 aa)

FSERNKLGQGGFG-TVYKATLNN---------------------------GSQVAVKKLSLQ---------SNQG-------------------------
. . ...|.|||| .||.|....                           .. ||.||. .          .. .                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

KREFVNEITIITGIQHRNLVRLKGYCVEADERLLVYEFLNKGSLDRALFSSGSNAF------LDWQSRFQIAIGIARGLGYLHEESHV-QVIHRDIKASN
 ||| .|..|. . .| |.| |||.| .   . .| |..  |.|.. |... ...|      ..|. . .||. ||.|..|||  ||   .|||| |  |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH--SHNPPIIHRDLKSPN

ILL---D---------DKLQPKISDFGISKLFDLDKGFGVT-STKVAGTLGYMAPEYATRG---RLTAKADVFSYGILVLEIASGR
|||   .         .    ||.||||| .|   . |. .   .. |. |.||||    .     | |.|..|.|..  |. ...
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMF---QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase LRR8_y-2.AA Pkinase_Tyr 253-454 29 3e-36 123.41 Pfam 1-213 (270) Show / Hide 
Range on Protein: 253-454
Range on HMM: 1-213/270
Sequence Identity: 29% (64 aa)

FSERNKLGQGGFGTVYKATLN-----NGSQVAVKKLSLQSNQG---KREFVNEITIITGI-QHRNLVRLKGYCV-EADE--RLLVYEFLNKGSLDRALFS
 .   |||.| ||.|||.|..     .. .||||.|  .. .    ...| .|. | . . .| |.||| | |. . .    ..| |.  .|.|.  | .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

S-GSNAFLDWQSRFQIAIGIARGLGYLHEESHVQVIHRDIKASNILLDDKLQPKISDFGISKLFDLDKGFG-VTSTKVAGTLGYMAPEYATRGRLTAKAD
   ..  |. .   |... ||.|. ||..      ||||. | |.|...... ||.||| ...   ...   .....       ||||    |. | | |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VFSYGILVLEIAS-GRK
| |.|.|  || . |..
VWSFGVLMWEIFTYGEQ
Kinase LRR8_y-2.AA Dicty4-Unclassified 256-452 33 8.2e-35 116.64 In-house 4-204 (263) Show / Hide 
Range on Protein: 256-452
Range on HMM: 4-204/263
Sequence Identity: 33% (70 aa)

RNKLGQGGFGTVYKATLNNGSQVAVKKLSLQSNQGK----REFVNEITIITGIQHRNLVRLKGYCVEA----DERLLVYEFLNKGSLDRALF--SSGSNA
   .|.| |  |.|     |  |||||.   . .       .|  |. |   ||| |||...|||.           | ||. || |        |  . 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

FLDWQS--RFQIAIGIARGLGYLHEESHVQVIHRDIKASNILLDDKLQPKISDFGISKLFDLDKGFGVTSTKVAGTLGYMAPEYATRGRLTAKADVFSYG
 .   .     .|. ||.|. .||    . .||||||.||||.|     || |||||   |    |  . | .|||    .||       . |.||.||.
PIKLDDTLIIKYAFDIAQGMQHLHT---RNFIHRDIKSSNILMDKHFNIKIADFGISRVID----FNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

ILVLEIASG
..  | | |
MMLYELATG
Kinase LRR8_y-2.AA TK-Unique 253-451 23 4.2e-34 115.02 In-house 1-234 (294) Show / Hide 
Range on Protein: 253-451
Range on HMM: 1-234/294
Sequence Identity: 23% (56 aa)

FSERNKLGQGGFGTVYKATLNNGS-------QVAVKKLSLQSNQG-KREFVNEITIITGIQ-HRNLVRLKGYCVEAD-ERLLVYEFLNKGSLDRALFSSG
.   ...|.| ||.|..... ...       .||||.|   ...  |..| .|| .   .  | |.|.. |.|.. |   ....|.. .|.|.  | ...
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

SN-----------------------AFLDWQSRFQIAIGIARGLGYLHE--ESHVQVIHRDIKASNILLDDKLQPKISDFGISKLFDLDKGFGVTSTKVA
 .                       .... .. ...|..||.|. ||..  .   ...|||. |.|.|| .... ||.|||...  . ..    . ..  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRK---KIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

GTLGYMAPEYAT--RGRL-TAKADVFSYGILVLEIAS
  . .||||.    .|   | | || |.|.|  ||..
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase LRR8_y-2.AA TK 502-525 29 0.000399 8.88 In-house 463-486 (486) Show / Hide 
Range on Protein: 502-525
Range on HMM: 463-486/486
Sequence Identity: 29% (7 aa)

RVAMLCTQEHEEARPTMSDVVAML
.. . | ..  | |||.|... .|
DLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR8_y-2.AA TK-Unique 507-525 31 0.001795 7.98 In-house 276-294 (294) Show / Hide 
Range on Protein: 507-525
Range on HMM: 276-294/294
Sequence Identity: 31% (6 aa)

CTQEHEEARPTMSDVVAML
|.|. .| ||. .... .|
CWQWEPEERPSFRQIKHRL
Kinase LRR8_y-2.AA LRRK 505-527 30 0.17657 0.98 In-house 329-351 (351) Show / Hide 
Range on Protein: 505-527
Range on HMM: 329-351/351
Sequence Identity: 30% (7 aa)

MLCTQEHEEARPTMSDVVAMLLG
..| |.. . ||..|..|  |  
QHCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR8_y-2.AA Pkinase_Tyr 513-525 46 1.229388 2.78 Pfam 258-270 (270) Show / Hide 
Range on Protein: 513-525
Range on HMM: 258-270/270
Sequence Identity: 46% (6 aa)

EARPTMSDVVAML
| |||.|... .|
EDRPTFSEIHEQL