Gene LRR8_ag (S.moellendorffii)

LRR8_ag

Species: S.moellendorffii
Alias: LRR8_ag
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8

Sequence

Name Sequence Type Origin Length Description Download
LRR8_ag.AA Protein None 990 None Fasta, JSON
LRR8_ag.NA RNA None 2973 None Fasta, JSON
LRR8_ag.kin_dom Protein Kinase Domain None 202 None Fasta, JSON

Protein domain

Protein domains of LRR8_ag.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR8_ag.AA LRRNT_2 22-63 36 6.5e-15 51.36 Pfam 1-46 (46) Show / Hide 
Range on Protein: 22-63
Range on HMM: 1-46/46
Sequence Identity: 36% (17 aa)

AATERELLLEFKRGIVD-PR--NVLESWNAST-NPQVCSWKGIECD
...... ||.|| ...| ..  .||.|||.|.  .  |||.|..||
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR8_ag.AA LRR_1 91-112 17 4.498659 4.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 91-112
Range on HMM: 1-26/26
Sequence Identity: 17% (5 aa)

NLTSVRVTY-N--NF-DQPFPS--LERC
||..  . . |  |. .. .|.  .  .
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 114-136 29 0.332838 8.44 Pfam 1-26 (26) Show / Hide 
Range on Protein: 114-136
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

KLVYLDLSQ-N-WFR-GPLPEN-ISMI
.| .||||  | .   | .|.. .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 141-163 37 0.00775 14.23 Pfam 1-26 (26) Show / Hide 
Range on Protein: 141-163
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

PLRRLDLSY-N--AFTGPMPDA-LGEL
 |..||||. |   .||  |.  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 166-187 37 0.087919 10.49 Pfam 1-26 (26) Show / Hide 
Range on Protein: 166-187
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

TLQELVLSA-N--LFT-NLTPS-LGRL
.||.| ||  |   .| .. || .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 189-213 44 0.036117 11.86 Pfam 1-26 (26) Show / Hide 
Range on Protein: 189-213
Range on HMM: 1-26/26
Sequence Identity: 44% (13 aa)

NLTFLDVSS-N-INLL-RAFIPPE-LGNL
||. ||.|. |  ||     |||. . ||
NLQHLDLSGCNCCNLTGH--IPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 215-237 37 0.003419 15.49 Pfam 1-26 (26) Show / Hide 
Range on Protein: 215-237
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLVRLYLFNC---GLVGTIPPE-LGAL
.| .|.| .|    |.|.|||. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 239-261 37 0.069591 10.85 Pfam 1-26 (26) Show / Hide 
Range on Protein: 239-261
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

EIEDLELQS-N--NLTGSIPVE-LMYL
 .. | |.. |  ||||.|| . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 263-285 37 0.018866 12.86 Pfam 1-26 (26) Show / Hide 
Range on Protein: 263-285
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

KLKMLELYK-N--KLSGQIPYE-IGNL
.|. | |   |  .|.|.|| . . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 287-309 40 0.578031 7.59 Pfam 1-26 (26) Show / Hide 
Range on Protein: 287-309
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

LLTDLDASE-N--ALTGSIPTQ-VGGL
 |. || |  |   |||.||     .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 311-333 44 0.001156 17.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 311-333
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NLRILHLHL-N--RLTGSIPES-LADL
||..|.|   |  .|||.||.| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 335-357 37 11.30932 3.01 Pfam 1-26 (26) Show / Hide 
Range on Protein: 335-357
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLEQFTAFA-N--NLTGKIPES-LGKK
||.       |  ||||.||.| . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 383-405 44 0.006255 14.56 Pfam 1-26 (26) Show / Hide 
Range on Protein: 383-405
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

ALQNLSLYG-N--MLSGGIPES-FSDC
 || |.| | |   |.| ||.| |  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 359-382 33 1.521084 6.1 Pfam 1-26 (26) Show / Hide 
Range on Protein: 359-382
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RLSYVTLSQ-N--KLTGGVPPFICGGN
.| .  ||  |  .||| .|| .. . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 407-426 30 8.121965 3.52 Pfam 1-26 (26) Show / Hide 
Range on Protein: 407-426
Range on HMM: 1-26/26
Sequence Identity: 30% (8 aa)

SWVRLRLQD-N--HLEGPVPP---KL
.  .| |.. |  .|.| .||   .|
NLQHLDLSGCNCCNLTGHIPPSCFNL
LRR_1 LRR8_ag.AA LRR_1 431-453 33 0.015527 13.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 431-453
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLTVLELSS-N--RLNGSVTSD-IKNA
||..| ||. |  .| |.. .. . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 455-476 29 0.011517 13.62 Pfam 1-26 (26) Show / Hide 
Range on Protein: 455-476
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLGILRLDG-N--KFE-SLPDE-LGNL
.| .| |.| |  ... ..|.. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 478-491 35 34.972808 1.27 Pfam 1-17 (26) Show / Hide 
Range on Protein: 478-491
Range on HMM: 1-17/26
Sequence Identity: 35% (6 aa)

NLIELTASD-N--SISG
|| .|  |. |  ...|
NLQHLDLSGCNCCNLTG
LRR_1 LRR8_ag.AA LRR_1 499-521 37 5.8e-05 21.76 Pfam 1-26 (26) Show / Hide 
Range on Protein: 499-521
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLEALNLSH-N--RLSGAIPAD-IRNC
.|. |.||. |  .|.| || . . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 523-545 40 0.000544 18.32 Pfam 1-26 (26) Show / Hide 
Range on Protein: 523-545
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLTSLDFSA-N--SLSGSIPSS-LASL
.|..||.|  |  .|.|.||.| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 547-569 40 0.000355 18.98 Pfam 1-26 (26) Show / Hide 
Range on Protein: 547-569
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLNMLDLSN-N--HLSGDVPSA-LGNL
.|  ||||. |  .|.|..|.  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_ag.AA LRR_1 570-593 37 0.0132 13.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 570-593
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

LLSSLNISN-N--NLSGRIPESWTRGF
 | .|..|. |  ||.| ||.|.  ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR8_ag.AA TKL 692-954 21 1.5e-60 207.49 In-house 1-364 (364) Show / Hide 
Range on Protein: 692-954
Range on HMM: 1-364/364
Sequence Identity: 21% (80 aa)

IGTGRSGKVYRVDLAS---------GHSLAVKQISRSDHSLGDD-------------------------YQYQSEVRTLGHIRHRSIVRLLSCCWNADT-
|| |..|.||.  .           |   |||.... . .. ..                          .   |.. .  .||  ||... .| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------DLLIFEYMPNGSLRDVLHSKKVANLDWNTRYRIALRAAQALSYLHHDCS-----PPLLHRDVKSANILLDADYE--------------
              .. ||.|.|||...||        |. | |.|| .|....||| .       ||..||| ||.|||.| ...              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

PKLADFGITKLLKGSDDETMTN------------------IAGSYGYIAPEY-----TYT-----------LKVSTKSDTYSFGVVLLELVTGKRPVDSE
.|..|||. . ...| . ..|                   . |.... |||       ||           .. |.|.| ||||.|| |..|..|| . .
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

FGDLDIVR----WVKGRVQAKGPQVVLDTRVSA-----SAQDQMIMLLDVALLCTKASPEERPTMRRVVEML
  .  |..    .    |  || .  .... .         | .  . . .  | .. ||.||.. .... |
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR8_ag.AA IRAK 687-891 32 4.7e-47 162.64 In-house 2-227 (317) Show / Hide 
Range on Protein: 687-891
Range on HMM: 2-227/317
Sequence Identity: 32% (74 aa)

DENNVIGTGRSGKVYRVDLASGH-SLAVK-QISRSDHSLGD-DYQYQS---EVRTLGHIRHRSIVRLLSCCWNADTDLLIFEYMPNGSLRDVLHSKK-VA
...|.|| |  | |||...       |||  ..  | | .  . . |.   |....  .||  || |.  |   .   |...|||||||.| |.  .   
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

N---LDWNTRYRIALRAAQALSYLHHDCSP-PLLHRDVKSANILLDADYEPKLADFGITKLL--KG--SDDET---MTN-IAGSYGYIAPEYTY--TLKV
    | | .|  |.. .| .. .|| . .  |. |.|.||||||||.. .||..|||       ..   . .    ||. . |.  | .||. .  . . 
PPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQL

STKSDTYSFGVVLLELVTGKRPVDSE
..|.|.||||.||||..|| |.|...
TKKTDVYSFGIVLLEVLTGCRAVYDD
Kinase LRR8_ag.AA TKL-Unique 690-887 31 7.1e-43 148.76 In-house 3-233 (290) Show / Hide 
Range on Protein: 690-887
Range on HMM: 3-233/290
Sequence Identity: 31% (74 aa)

NVIGTGRSGKVYRVDLASGHSLAVKQIS-RSDHSLGDDYQYQSEVRTLGHIR-HRSIVRLLSCCW----NADTDLLIFEYMPNGSLRDVLHS--------
|.||.| .|.||..  . | . |.||..  .| |.       .||...  .. |  ||..   |      .    .. ||.| |||.||||         
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

KKVANLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDAD-----YEPKLADFGITKLLKGSDDETMTNI--------AGSYGYIAPEYTYT
..  .|... |...|...||.. |||| |.|| .||| || |.|.| .     .  |..|||. |... ....| ...         ||. ..||| .  
NNNCKLNMQQRVKMAIDIAQGMYYLHH-CEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--LKVSTKSDTYSFGVVLLELVTGKR------P
   . |.||| ||||.|| |..|.|.      |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR8_ag.AA MLK 686-887 27 9.7e-43 146.11 In-house 1-235 (291) Show / Hide 
Range on Protein: 686-887
Range on HMM: 1-235/291
Sequence Identity: 27% (66 aa)

LDENNVIGTGRSGKVYRVDLASGH----SLAVKQIS-RSDHSLGDDY----QYQSEVRTLGHIRHRS----IVRLLSCCWNADT-DLLIFEYMPNGSLRD
...  .|| | .|||..            .|||..  | . . .| |    . . |.| | ...|.     |.... .| .     ... ||...||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

VLHSKKV------------ANLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDA------DYEPKLADFGITKLLKGSDDETMTNIAGSYG
|||...             .. |     ..||  |....||| .  .|. ||| || |||.|.      .   | .|||. . .. .. ..|.. ||.| 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YIAPEYT---YTLKVSTKSDTYSFGVVLLELVTGKRP
. ||| .      |.| |.| .|.|||| |..|.. |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRR8_ag.AA Pkinase 686-885 25 4.1e-39 139.39 Pfam 1-209 (293) Show / Hide 
Range on Protein: 686-885
Range on HMM: 1-209/293
Sequence Identity: 25% (54 aa)

LDENNVIGTGRSGKVYR-VDLASGHSLAVKQISRSDHSLGDDYQYQS--EVRTLGHIRHRSIVRLLSCCWNADTDLLIFEYMPNG----SLRDVLH---S
.    .|| | .|.||. ..  .|.  |||.|.... . . |..     |.. . ...|  ||||. .. . |   ...||...|    .| |...   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KKVANLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDADYEP----KLADFGITKLLKGSDDETMTNIAGSYGYIAPEYTY-TLKVSTKSD
...  .....  ....  ...| |.|       .|||.|..|||.| ....    |..|||. |...   .. || ..|...|.|||      . ..|.|
GCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

TYSFGVVLLELVTGK
 .|.|..| |...|.
MWSCGCILYEMLCGR
Kinase LRR8_ag.AA TK 686-954 15 8.7e-35 113.49 In-house 1-486 (486) Show / Hide 
Range on Protein: 686-954
Range on HMM: 1-486/486
Sequence Identity: 15% (74 aa)

LDENNVIGTGRSG---KVYRVDLASG--------------------------HSLAVKQISRSDHSLGDDYQY---------------QSEVRTLGH--I
.   ...| |  |   .||.  . ..                          .  |||..   |..  .. .                 .|   . |   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHRSIVRLLSCCWNADTD------------LLIFEYMPNGS----LRDVLHSKKVA--------------------------------------------
.|  ||||. .|   ..             ... ||||.|.    ||| |....                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------NLDWNTRYRIALRAAQALSYLHHD----CSPPLLHRDVKSANILLDADYE-----------PKLADFGIT
                              .|.  ..  ... .|....|||        . . |||.   |.|.. ..             |.|||| .
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----LLKGSDDETMTNIAGSYG----------------------------YIAPEYTY---------TLKVSTKSDTYSFGVVLLELVT-G-KRPV--
.     | .  ....    ..|||                            . |||            . | .|||| .||||.. |..| | . .   
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGG

DS-------EFGDLDIVRWVKG--------------RVQAKGPQVVLD---TRVSASAQDQMIMLL-DVALLCTKASPEERPTMRRVVEML
 |       . .. .... ..               | . . |.   |   .|  .  .  .  .. |. . | .. ||.|||.. ..|.|
MSNQDVWKDG-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR8_ag.AA RIPK 692-887 28 6.2e-33 109.54 In-house 1-227 (290) Show / Hide 
Range on Protein: 692-887
Range on HMM: 1-227/290
Sequence Identity: 28% (65 aa)

IGTGRSGKVYRVDLASGHSLAVKQISRSDH----SLGDDYQYQSEVRTLGH-IRHRSIVRLLSCCWNA----DTDL--LIFEYMPNGSLRDVLHSKKV--
.| | .|.|...  ..    ..| .. . |     .  . .||.| .   | .|.. ||...  |       |  |  .  |||.|||| ..||.|    
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-ANLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDADYEPKLADFGITKLLKGS---DDET-------MTNIA--GSYGYIAPEYTY--TL
   . |  | |.    . .  || |.  ||..||| | .|||.|...  |.||||  . . .|   .|.        |.     |   |..||       
HHPDPWPLRCRMIHEISCGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

KV----STKSDTYSFGVVLLELVTGKRP
|     ..|.| |||..|. |. |.| |
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR8_ag.AA LRRK 686-889 24 2.7e-31 107.97 In-house 1-284 (351) Show / Hide 
Range on Protein: 686-889
Range on HMM: 1-284/351
Sequence Identity: 24% (71 aa)

LDENNVIGTGRSG-KVYRVDLAS---------------------------GHSLAVKQISRS-------------------------------DHSLGDD
| ... || | .| .||| .. .                           . . |.|.. |                                . ..   
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YQ-YQSEVRTLGHIRHRSIVRLLSCCWNADTDLLIFEYMPNGSLRDVLHSKK-VA------NLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANI
.. .. ||  . | .| .|| |.  | .  .  .. ||.|.|.| ..||.||  .      ...|.....|||  | .. || |...||..||| || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDLKSPNI

LL---D---------ADYEPKLADFGITKLLKGSDDET-MTNIAGSYGYIAPEYTY---TLKVSTKSDTYSFGVVLLELVTGK-RPVD
||   .         |..  |.|||||. .   .. ..      |  |. |||      .   ..|.|.||||..| ||.|.. .| |
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LRR8_ag.AA S_TKc 686-961 22 6.4e-31 109.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 686-961
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

LDENNVIGTGRSGKVYRVDLAS-GHSLAVKQISRSDHSLGDDYQYQSEVRTLGHIRHRSIVRLLSCCWNADTDLLIFEYMPN--GSLRDVLHSKKVAN--
 .  ..|| |  ||||..   . |.  |.|.|.          . ..|.. | . .|  ||.|. .. . |   ...||...  |.|.|......     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDADYEPKLADFGITKLLKGSDDETMTNIAGSYGYIAPEYTYTLKVST-KSDTYSFGVV
  ..  .  ...   ..|| |.|       .|||.| .|||||   . |..|||. ..|        | . |.  |.|||     . .. |.| .|.|..
FPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLELVTGKRPVDSEFGDLDIVRWVKGRVQAKGPQVVLDTRVSASAQDQMIMLLDVALLCTKASPEERPTMRRVVE--MLEKIQPEA
| |...|. | .    .  . . ..                          ..|    | .  ||.|||   . .  .. |. |  
LYEMLCGYPPFP---QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR8_ag.AA STE 686-887 22 4.2e-25 85.67 In-house 1-267 (359) Show / Hide 
Range on Protein: 686-887
Range on HMM: 1-267/359
Sequence Identity: 22% (61 aa)

LDENNVIGTGRSGKVYRV-DL------ASGHS---------LAVKQISRSDHSL--------------GDDY-QYQSEVRTLGHIR--HRSIVRLLSCCW
..   .|| | .|.||.  .        .|            |.||.. .. .                ..  |.. |.... . .  |  ||. . |. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

NA------DTDLLIF-EYMPNGSLRDVLHSKKVANLD------------WNTRYRIALRAAQA-LSYLHHDCSPPLLHRDVKSANILLDADYEPKLADFG
.       |..| |. |||..|||.|....|.  . .             .   .|.    .. |.|||        |||.|.|||||      ||.|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

ITKLLKG---------------SDDETMTNIAGSYGYIAPEYTYT------LKVSTKSDTYSFGVVLLELVTGKRP
. . |                 . ..  . ..|.  . |||           . .||.| .|.| ...|..||| |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase LRR8_ag.AA TK-Unique 686-883 22 2e-24 81.23 In-house 1-234 (294) Show / Hide 
Range on Protein: 686-883
Range on HMM: 1-234/294
Sequence Identity: 22% (53 aa)

LDENNVIGTGRSGKVYRVDLASGH------SLAVKQISRSDHSLGDDYQYQSEVRTLGHIR-HRSIVRLLSCCW-NADTDLLIFEYMPNGSLRDVLHSKK
|  ..|||.|. | |.| .. ..       . ..    . .... |.... .| . . ..  |  ||..| ||  . .  ..|.||.|.|.|.. |....
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

VA------------------------NLDWNTRYRIALRAAQALSYLHH--D-CSPPLLHRDVKSANILLDADYEPKLADFGITKLLKGSDDETMTNI--
 |                         ..  . |..|   |....||.   . .     |||. . |.||  |.. |..|||...  ......   ..  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI----VHRDLCARNVLLTEDKVCKICDFGMAR--DVYTNGVYSMMCS

--AGSYGYIAPEYTY--TLKV-STKSDTYSFGVVLLELVT
    .. . |||. .  .    .|||| .||||.. |..|
QGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase LRR8_ag.AA Dicty4-Unclassified 732-887 33 3.8e-24 79.56 In-house 48-207 (263) Show / Hide 
Range on Protein: 732-887
Range on HMM: 48-207/263
Sequence Identity: 33% (56 aa)

EVRTLGHIRHRSIVRLLSCCWNA----DTDLLIFEYMPNGSLRDVLH-----SKKVANLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDA
||  || | |   |..   | |      |   . | |. | |  | |      ..   ||     ..|.  || . .||   .  . |||.||.|||.| 
EVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDK

DYEPKLADFGITKLLKGSDDETMTNIAGSYGYIAPEYTYTLKVSTKSDTYSFGVVLLELVTGKRP
..  | |||||      .   .|| |||     .||         ||| ||....| ||.||  |
HFNIKIADFGISRVI--DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEP
Kinase LRR8_ag.AA Pkinase_Tyr 731-887 26 2e-20 69.83 Pfam 52-214 (270) Show / Hide 
Range on Protein: 731-887
Range on HMM: 52-214/270
Sequence Identity: 26% (44 aa)

SEVRTLGHI-RHRSIVRLLSCCW-NADT--DLLIFEYMPNGSLRDVLHSK--KVANLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDADY
.|.... .. .|  ||||. .|    .    ....||||.|.|.| |...     .|.  .   ...  |....||.      . |||.   |.|.. . 
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENN

EPKLADFGITKLL-KGSDD-ETMTNIAGSYGYIAPEYTYTLKVSTKSDTYSFGVVLLELVT-GKRP
  | .||| .... . .    . ..        |||   . | .|||| .||||.. |..| |. |
VVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase LRR8_ag.AA TyrKc 686-954 21 2.6e-17 57.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 686-954
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

LDENNVIGTGRSGKVYRVDLASGHSLAVKQISRSDHSLGDDYQYQSEVRTLGHI--RHRSIVRLLSCCWNA-------DTDLLIFEYMPNGSLRDVLHSK
.  . ..| |  |.||.  .      ||| .  .           .| | . ..  .|  ||||. .|          .  ....||||.|.|.| |...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

KVANLDWNTRYRIALRAAQALSYLHHDCSPPLLHRDVKSANILLDADYEPKLADFGITKLLKGS------DDETMT----NIA--GSYGYIAPEYTYTLK
.   | . .   ... .|.  .|||.    .. |||    |.|.....  | .||| .. ..        .|  ..    .      .   |||   . |
RPK-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

VSTKSDTYSFGVVLLELVT-GKRPVDSE----FGDLDIVRWVKGRVQAKGPQVVLDTRVSASAQDQM------IMLLDVALLCTKASPEERPTMRRVVEM
 .|||| .||||.. |. | |. |   .      . .....|| .   . |. ..           |        . .. . | .. ||.|||.. ..| 
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---------P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHEC

L
.
F
Kinase LRR8_ag.AA TK-Unique 936-954 42 0.000864 9.09 In-house 276-294 (294) Show / Hide 
Range on Protein: 936-954
Range on HMM: 276-294/294
Sequence Identity: 42% (8 aa)

CTKASPEERPTMRRVVEML
|.. .|||||. | .. .|
CWQWEPEERPSFRQIKHRL
Kinase LRR8_ag.AA LRRK 935-956 27 0.001222 8.73 In-house 330-351 (351) Show / Hide 
Range on Protein: 935-956
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

LCTKASPEERPTMRRVVEMLEK
.| .. |..||..  .|. |. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR8_ag.AA Pkinase_Tyr 934-954 38 0.014607 9.3 Pfam 250-270 (270) Show / Hide 
Range on Protein: 934-954
Range on HMM: 250-270/270
Sequence Identity: 38% (8 aa)

LLCTKASPEERPTMRRVVEML
..| .. ||.|||.. ..|.|
KQCWHYDPEDRPTFSEIHEQL
Kinase LRR8_ag.AA Dicty4-Unclassified 936-954 36 0.015506 4.46 In-house 245-263 (263) Show / Hide 
Range on Protein: 936-954
Range on HMM: 245-263/263
Sequence Identity: 36% (7 aa)

CTKASPEERPTMRRVVEML
|   .|  ||||  ... |
CWHNDPNKRPTMNQIIQYL
Kinase LRR8_ag.AA MLK 936-954 36 0.01964 4.41 In-house 273-291 (291) Show / Hide 
Range on Protein: 936-954
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CTKASPEERPTMRRVVEML
| .. |..||..| .|. |
CWNQDPHKRPSFRQIVQHL
Kinase LRR8_ag.AA IRAK 929-954 23 0.029906 3.98 In-house 292-317 (317) Show / Hide 
Range on Protein: 929-954
Range on HMM: 292-317/317
Sequence Identity: 23% (6 aa)

LLDVALLCTKASPEERPTMRRVVEML
....|. |. .   .|..|. |.. |
MCQCACCCGHHRANRRCDMAWVMQQL