Gene LRRI_a-2 (S.moellendorffii)

LRRI_a-2

Species: S.moellendorffii
Alias: LRRI_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRRIa

Sequence

Name Sequence Type Origin Length Description Download
LRRI_a-2.AA Protein None 886 None Fasta, JSON
LRRI_a-2.NA RNA None 2658 None Fasta, JSON
LRRI_a-2.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of LRRI_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 LRRI_a-2.AA LRR_1 420-442 29 1.050526 6.67 Pfam 1-26 (26) Show / Hide 
Range on Protein: 420-442
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

RIIELNLSS-S--GLKGTISLS-ITKL
.. .|.||.     | |.|. | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRRI_a-2.AA LRR_1 444-465 33 0.002008 16.31 Pfam 1-26 (26) Show / Hide 
Range on Protein: 444-465
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

HLTKIYLDN-N--ALTGRVPD--FSSL
.|....|.. |   ||| .|.  | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRRI_a-2.AA TKL 598-863 22 2.6e-64 219.98 In-house 1-364 (364) Show / Hide 
Range on Protein: 598-863
Range on HMM: 1-364/364
Sequence Identity: 22% (84 aa)

IGEGSFGPVYYGCLPN---------GVEVAVKVLSSNSKQGY---------------------------QEFQTEIDILSVVHHKNLVPFLGYCTQKSK-
||.|.|| || | . .         | .||||...|.. .                             ...  || ..|  .| |.|.|.|||.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LILVYEFLSNGTLREHLYGEGKRYPTLSWKTRLGIALDAAQGLEYLHT----SCNLH--IIHRDVKTSNILLSFDMV-----------
            | .|.|. ..|.|...|           |  |. .|||.|.|..|||.    .|     ||||| |..|||.  ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AKLSDFGLSKFYD---SNKASHVSTG--------------IKGTPGYLDPEYHSYS----------------RLTEKSDVYSFGVVLFEIVCGREPL
   .|..|||||.| .   .....  ...              . |||... ||    .                  .||.||||||.||.||.....  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-P

NFTLLEEQIVLS---EWACKELEKGNLRTVIDPSLS-----DYGENAALKVLEVARKCVERSPHRRPNMSTVVIQL
 . . .......   |.  .   . .||  |.|  .        ...   . . . .| .  |. ||...... .|
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRRI_a-2.AA IRAK 592-792 34 4.6e-59 202.53 In-house 1-221 (317) Show / Hide 
Range on Protein: 592-792
Range on HMM: 1-221/317
Sequence Identity: 34% (77 aa)

SNFKRVIGEGSFGPVYYGCLPNGV-EVAVK----VLSSNSKQGYQEFQT---EIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNGTLREHLYGEGKR
..  ..|||| || || | . |    .|||    . ... ..  |.||.   |. ...  .|.|.||..||||. ... |||....||.|.  | . .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

YP--TLSWKTRLGIALDAAQGLEYLHTSC-NLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFY--DSNKASHVS-----TGIKGTPGYLDPEYHS--YSR
 |   ||| .|. |.. .| |...||.      |||.|.|..||||  ....|..||||  |    |.| ....       ..||  |. ||.      .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTEKSDVYSFGVVLFEIVCGR
|| |.||||||.|| |.. |.
LTKKTDVYSFGIVLLEVLTGC
Kinase LRRI_a-2.AA TKL-Unique 594-789 32 1.6e-48 167.54 In-house 1-222 (290) Show / Hide 
Range on Protein: 594-789
Range on HMM: 1-222/290
Sequence Identity: 32% (73 aa)

FKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNSKQG---YQEFQTEIDILSVVH-HKNLVPFLGYCT----QKSKLILVYEFLSNGTLREHLY------G
|  .||||..|.|| |   .| .||.|... |...     |||  |. .... | |.|.| . |||.    . .....| |... |.|...|        
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

EGKRYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFD-----MVAKLSDFGLSKFYDSNKASHVS-------TGIKGTPGYLDPEYH
  ..  .|... |. .|.|.|||..|||..    ||||| |.||.|.. .     . .|..||||||| ... .. ..       .. .|.. .. ||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SY--SRLTEKSDVYSFGVVLFEIV
.   .  .|||||||||.|| ||.
RMNFCQYSEKSDVYSFGIVLWEIA
Kinase LRRI_a-2.AA Dicty4 593-794 36 4.9e-48 158.38 In-house 2-216 (277) Show / Hide 
Range on Protein: 593-794
Range on HMM: 2-216/277
Sequence Identity: 36% (79 aa)

NFKRVIGEGSFGPVYYGCLPNGVEVAVKVL-SSNSK---QGYQEFQTEIDILSVVHHKNLVPFLGYCT----QKSKLILVYEFLSNGTLREHLYG---EG
|.   ||.|||| || |    | |||||.| . | .      .||  |..|..   | |.. |.|.||    ...|.  | |... |.| . |     | 
NIEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

KRYPTLSWKTRLG---IALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASHV-STGIKGTPGYLDPEYHSYSRLTEKSD
.   .|.| ...    .|.|||.|. .|| .||  ||||| |..|.| . ....| .|||||.     .      .. .|||..  ||     . .||.|
QQSIKLDWPLIKRAMRMAFDAARGMNWLH-CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSFGVVLFEIVCGREP
||||| ||.||. . ||
VYSFGIVLWEILTRQEP
Kinase LRRI_a-2.AA TK 592-794 17 1.7e-47 156.8 In-house 1-394 (486) Show / Hide 
Range on Protein: 592-794
Range on HMM: 1-394/486
Sequence Identity: 17% (71 aa)

SNFKRVIGEGSFG---PVYYGCLPNG--------------------------VEVAVKVLSSNSKQGYQEFQT-----------------EIDILS--VV
  . ...||| ||    || | . ..                          ..||||.| . . .  .||.                  |. ...  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHKNLVPFLGYCTQKSK------------LILVYEFLSNGT----LREHLYGEGKRYPT-----------------------------------------
||.|.| ..|.|||.              ...| |. ..|     ||..|    ..  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSWKTRLGIALDAAQGLEYLHTSCNL----HIIHRDVKTSNILLSFDMV-----------AKLSDFGLS
                               |. ...| .....|.|.|||| |.|     ...|||. . |.|.. ..|           .|..|||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH-SKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-------FYDSNKASHVSTGIKGTPG-------------------------YLDPEYHS---------YSRLTEKSDVYSFGVVLFEIVC-GREP
.        .. ..   .... .||..                         .. ||            | . |.||||.||||...||.  |.||
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LRRI_a-2.AA Pkinase 592-794 30 1.9e-44 158.22 Pfam 1-211 (293) Show / Hide 
Range on Protein: 592-794
Range on HMM: 1-211/293
Sequence Identity: 30% (66 aa)

SNFKRVIGEGSFGPVYYGCLPNGVE-VAVKVLSSNSKQGYQEFQT-----EIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNG----TLREHLYGEG
  ..|.||.|||| || ..  .  . ||||...   ..  .. ||     || |.  ..|.| | ...... |... .| |.. .|     | ... .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

KRYPTL--SWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVA----KLSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHS-YSRLTE
.|. ..  |...   ...  ..||||.|      |||||.| .|||.. ...     |..||||.|..| .  ..  |.. |||.|. || .  ..  . 
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KSDVYSFGVVLFEIVCGREP
|.|..|.|..|.| .||| |
KVDMWSCGCILYEMLCGRPP
Kinase LRRI_a-2.AA Pkinase_Tyr 593-794 31 9e-44 148.87 Pfam 2-214 (270) Show / Hide 
Range on Protein: 593-794
Range on HMM: 2-214/270
Sequence Identity: 31% (70 aa)

NFKRVIGEGSFGPVYYGCLP-----NGVEVAVKVLSSNSKQGY---QEFQTEIDILSVV-HHKNLVPFLGYCT-QKSK--LILVYEFLSNGTLREHLYGE
 | ...|||.|| || | .      ....||||.|  .. .     ..|  |. |..   ||.|.| ..| || |.    ...| |.  .| |...|   
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

--GKRYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASH-VSTG-----IKGTPGYLDPEYHSYSRL
  .|. .|...   |..... |.|.|||.      .||||. . |.|.. ..|.| .||||..    |.    ...|     || ..    ||  .|.. 
REDKQPLTMKD--LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMA----PECINYGKF

TEKSDVYSFGVVLFEIVC-GREP
|.||||.||||...||.  |..|
TTKSDVWSFGVLMWEIFTYGEQP
Kinase LRRI_a-2.AA TyrKc 592-863 25 9.2e-44 152.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 592-863
Range on HMM: 1-280/280
Sequence Identity: 25% (75 aa)

SNFKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNSKQGYQEFQTEIDILSVV--HHKNLVPFLGYCTQK-------SKLILVYEFLSNGTLREHLYGEGK
  .....||| || || | .   ..||||.| ...    ..|  |. |.. .  ||.|.| ..|.|||.         | .| |. ..| |...|   ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RYPTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSN------KASHVSTGIKGTPG-----YLDPEYHSYSR
.   |..|. | .....|.| ||||     ..||||  . |.|.. . ..| ||||||.. ..       |   .... ||. .      . ||   |..
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

LTEKSDVYSFGVVLFEIVCGREPLNFTLLEEQIVLSEWACKELEKGNLRTVIDP-----SLSDYGENAALKVLEVARKCVERSPHRRPNMSTVVIQL
 |.||||.||||...||    ..      ..  .  . . . ...|. .   .      .       .  .. .. ..| .. |. ||..|... ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRRI_a-2.AA Dicty5 593-794 33 1.1e-38 130.77 In-house 2-202 (260) Show / Hide 
Range on Protein: 593-794
Range on HMM: 2-202/260
Sequence Identity: 33% (69 aa)

NFKRVIGEGSFGPVYYGCLPNGVEVAVKVLSSNS--KQGYQEFQTEIDILSVVH--HKNLVPFLGYCTQKSKL-ILVYEFLSNGTLREHLYGEGK-RYPT
 |  .|  |. | || |   .|  ||.||.|.        .||. |. |.|..   | |.. ..|  ..  |    | |. .||.|.. |    |     
SFHDWIASGASGRVYNGIY-KGMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHSYSRLTEKSDVYSFGVVLF
... ..| .|.|.||....|| | |  |||||.|  |.|.  .  .|. ||| | | |  .  |  . . ||. .  .|       ..| ||||||.||.
IAYFQQLHMAIDIAQSMRHLH-SMN--IIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRY--HMTMHV-GTQCWMACELFNGQPYHQKCDVYSFGIVLW

EIVCGREP
|.    ||
EMFTRKEP
Kinase LRRI_a-2.AA Ciliate-E2 592-792 21 1.3e-38 130.18 In-house 1-293 (365) Show / Hide 
Range on Protein: 592-792
Range on HMM: 1-293/365
Sequence Identity: 21% (63 aa)

SNFKRVIGEGSFGPVYYGCL---PN------------------GVEVAVKVLSSNSKQGYQEFQTEIDILSVVH----------------HKNLVPFLGY
 .| ..||.|.|| ||...    ..                  .| .  . . ...|.. ...  ||.|.  ..                |.|.. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CT--QKSKLILVYEFLSNGTLREHLY---GEGKRYPT----LSWKTRLGIALDAAQ---------------GLEYLHTSCNLHIIHRDVKTSNILLSFDM
    ..... || |... |.|.....      .  ..    ...| .. |    .|               .|||||   |  ||||| | .|||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF----

VAKLSDFGLSKFYDSN----------------KASHVSTGIK-------------GTPGYLDPEYHSYSR---------LTEKSDVYSFGVVLFEIVCGR
  |..||||||.|| .                   ....|.              |||||. || ...            ..|.|..|.||.|.| ..|.
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK
Kinase LRRI_a-2.AA MLK 592-794 27 2.3e-38 130.72 In-house 1-235 (291) Show / Hide 
Range on Protein: 592-794
Range on HMM: 1-235/291
Sequence Identity: 27% (67 aa)

SNFKRVIGEGSFGPVYYGCLPNGV----EVAVKVLSSNSKQGYQE-------FQTEIDILSVVHHKN----LVPFLGYCTQK-SKLILVYEFLSNGTLRE
 .|...||.|||| |. |   |      .||||   ..     ..       |..|. .|... |.|     ..|.| |.|  ... .| |....| | .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLYG-EGKRYP---------TLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSF------DMVAKLSDFGLSK-FYDS--NKASHVSTGIK
 |.| ..| ..         . .    . .||. |.|..|||      ||||| | .|||..       ....| .|||.|. ....  |.     .. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNM-----MSNA

GTPGYLDPEY---HSYSRLTEKSDVYSFGVVLFEIVCGREP
||. .  ||       .. .||.||.|.|||| |.. ...|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRRI_a-2.AA S_TKc 592-867 23 5.1e-38 133.54 SMART 1-231 (231) Show / Hide 
Range on Protein: 592-867
Range on HMM: 1-231/231
Sequence Identity: 23% (67 aa)

SNFKRVIGEGSFGPVYYGCLPN-GVEVAVKVLSSNSKQGYQEFQTEIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSN--GTLREHLYGEGKRYPT--
  . |.||.|.|| || .   . | .||.|...       . .. ||.||.  ||.|.| .....   ..| .| |....  |.|....   |.. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSKFYDSNKASHVSTGIKGTPGYLDPEYHSYSRLTE-KSDVYSFGVVL
..  .   ..   ...|||.|   ...|||||.| .||||.   . |..||||....         | . ||| |. ||       .  |.|..|.|..|
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

FEIVCGREPLNFTLLEEQIVLSEWACKELEKGNLRTVIDPSLSDYGENAALKVLEVARKCVERSPHRRPNMSTVVI-----QLREAI
.| .||. |       .. .. .  .                          ...  ||| .. | .||    .        . . .
YEMLCGYPPFP-----QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRRI_a-2.AA LRRK 592-794 26 1.8e-37 130.14 In-house 1-282 (351) Show / Hide 
Range on Protein: 592-794
Range on HMM: 1-282/351
Sequence Identity: 26% (78 aa)

SNFKRVIGEGSFG-PVYYGCLPN---------------------------GVEVAVKVLSS----------NSKQ------------------------G
  . . ||.|.|| .|| . . .                           . .||.|..            ||                           
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

YQEFQTEIDILSVVHHKNLVPFLGYCTQKSKLILVYEFLSNGTLREHLYGEGKRY-----PTLSWKTRLGIALDAAQGLEYLHTSCNLHIIHRDVKTSNI
..||. |. |.|  .| |.|. .|.| .   |..| |....|.| ..|  . .       . .|| ..| |||. | |.|||| |.|  ||||| |. ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL-SF-----------DMVAKLSDFGLSK--FYDSNK-ASHVSTGIKGTPGYLDPEYHSY---SRLTEKSDVYSFGVVLFEIVCGR-EP
|| |.           ...||..|||.|   ... .. |.    |  |.||.. ||   |   .  |||.|.||||..|.|.. ..  |
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAK----GCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase LRRI_a-2.AA TK-Unique 592-790 27 1.3e-36 123.85 In-house 1-234 (294) Show / Hide 
Range on Protein: 592-790
Range on HMM: 1-234/294
Sequence Identity: 27% (66 aa)

SNFKRVIGEGSFGPVYYGCLPN-------GVEVAVKVLS-SNSKQGYQEFQTEIDILSVVH-HKNLVPFLGYCTQKS-KLILVYEFLSNGTLREHLYGEG
.....|||||.||.|. | . .        . |||| |  .....  |.|  || ... .  |.|.| .||.|| ..    ...|....|.|. .|   .
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-------------------KRYPT---LSWKTRLGIALDAAQGLEYLHT-SCNLHIIHRDVKTSNILLSFDMVAKLSDFGLSK-FYDSNKASHVSTGIKG
                   ...|    .| |. . .| . |.|.|||.   ..   .|||. ..|.||. | |.|..|||...  |. |..   ... . 
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI--VHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGR

TPG-YLDPEYHS--YSRL-TEKSDVYSFGVVLFEIVC
.|  .. ||. .  .    |.||||.||||...||..
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase LRRI_a-2.AA TK 832-863 21 0.001092 7.39 In-house 454-486 (486) Show / Hide 
Range on Protein: 832-863
Range on HMM: 454-486/486
Sequence Identity: 21% (7 aa)

ENAALKVL-EVARKCVERSPHRRPNMSTVVIQL
.... ... .. ..| .. | .||..|... ||
PHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRRI_a-2.AA MLK 844-863 35 0.001984 7.91 In-house 272-291 (291) Show / Hide 
Range on Protein: 844-863
Range on HMM: 272-291/291
Sequence Identity: 35% (7 aa)

KCVERSPHRRPNMSTVVIQL
.| .  ||.||... .| .|
QCWNQDPHKRPSFRQIVQHL
Kinase LRRI_a-2.AA IRAK 823-863 26 0.012579 5.33 In-house 277-317 (317) Show / Hide 
Range on Protein: 823-863
Range on HMM: 277-317/317
Sequence Identity: 26% (11 aa)

IDPSLSDYGENAALKVLEVARKCVERSPHRRPNMSTVVIQL
||.  .. ..| ... . .|  |...   ||. |  |. ||
IDHRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase LRRI_a-2.AA TK-Unique 845-863 26 0.160449 1.16 In-house 276-294 (294) Show / Hide 
Range on Protein: 845-863
Range on HMM: 276-294/294
Sequence Identity: 26% (5 aa)

CVERSPHRRPNMSTVVIQL
|  ..|. ||. .... .|
CWQWEPEERPSFRQIKHRL
Kinase LRRI_a-2.AA Pkinase_Tyr 843-863 33 2.817645 1.56 Pfam 250-270 (270) Show / Hide 
Range on Protein: 843-863
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

RKCVERSPHRRPNMSTVVIQL
..| .  | .|| .| .. ||
KQCWHYDPEDRPTFSEIHEQL