Gene MLK-Un_f-1 (S.moellendorffii)

MLK-Un_f-1

Species: S.moellendorffii
Alias: MLK-Un_f-1
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
MLK-Un_f-1.AA Protein None 432 None Fasta, JSON
MLK-Un_f-1.NA RNA None 1299 None Fasta, JSON
MLK-Un_f-1.kin_dom Protein Kinase Domain None 239 None Fasta, JSON

Protein domain

Protein domains of MLK-Un_f-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Ank MLK-Un_f-1.AA Ank 74-106 48 1e-09 39.34 Pfam 1-33 (33) Show / Hide 
Range on Protein: 74-106
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

DSRTALHVAACEGKKETVELLIAEGADVNARDR
| .|.||.|.. | .| |..|.  ||||||.|.
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank MLK-Un_f-1.AA Ank 107-139 36 0.819469 7.19 Pfam 1-33 (33) Show / Hide 
Range on Protein: 107-139
Range on HMM: 1-33/33
Sequence Identity: 36% (12 aa)

WGSTPLADAEHYKCDEVSQILLAHGAQLADTSP
 | |||  | .. . || . || ||| .  .  
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD
Ank MLK-Un_f-1.AA Ank 46-73 35 3.171666 5.07 Pfam 6-33 (33) Show / Hide 
Range on Protein: 46-73
Range on HMM: 6-33/33
Sequence Identity: 35% (10 aa)

LLWSASLGDVAGVRALLGKGMDVNSTDF
| . .. |..  |. ||..| ||| .| 
LHLACRCGHTEVVKMLLQHGADVNAQDD
Kinase MLK-Un_f-1.AA TKL 169-405 23 3.4e-64 219.57 In-house 12-364 (364) Show / Hide 
Range on Protein: 169-405
Range on HMM: 12-364/364
Sequence Identity: 23% (83 aa)

GKWRG----------TKVFVKVISIDTKTGDDK------------------------LKEFINELSLALKLRHPNVVQFLGAVTQSIP------------
|||||          . | ||.....    ..|                         .....|. . ..|||||.|||.|..... .            
GKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWG

-VMLVMEHLPKGDLQSYMKKKGKPLKPKKALKFALDIARGLNYVHEFKP-----EPVIHSNLKPSNLLRDKAGH--------------LKITDFAFTKYA
  ..|||  |.|.| .|.        . . ...|||||||.|| |  .|      |.|| .||..|.| |. ..              .||.|| . .  
QLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFM

FND----------------------RQFVPDSGRYMAPELYRCE----------------DYDSKVDVFSFALIVQEMMEGVPPFPKLG----------E
...                      .  .  . |.||||. | .                .|. |.||.||...  |.. . .|. ...          |
SQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFE

EEVAKSYADGKRPPFK---------IKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKEV
|. .. . .|.||| .          .. . |...|.|...||. ||.||||| .| |. 
EMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLK-Un_f-1.AA TKL-Unique 169-405 29 1.4e-55 190.96 In-house 16-290 (290) Show / Hide 
Range on Protein: 169-405
Range on HMM: 16-290/290
Sequence Identity: 29% (81 aa)

GKWRGTKVFVKVISIDTKTGDDKLKEFINELSLALKLR-HPNVVQFLGAVT----QSIPVMLVMEHLPKGDLQSYMK---------KKGKPLKPKKALKF
|||||..| .|....  .   ....||.||...  ||. |||.|.. |. .    . .   .||| .| | | ..           .. ..| ... .|.
GKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKM

ALDIARGLNYVHEFKPEPVIHSNLKPSNLLRDKA-----GHLKITDFAFTKYAFND-RQFVP-----------DSGRYMAPELYRC--EDYDSKVDVFSF
|.|||.|..| |  .|  .|| .||.||.| | .        || || . | . .. . ..            .| |.||||. |   ..|. |.||.||
AIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSF

ALIVQEMMEGVP------PFPKLGEEEVAKSYAD---GKRPPFKIKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKEV
. .. |. ..        |. ..  |....  ..   ..|||    |   |. ..|||..|||.|| .|||| .| .. 
GIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPI---PNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLK-Un_f-1.AA LRRK 169-407 24 1.7e-40 140.89 In-house 19-351 (351) Show / Hide 
Range on Protein: 169-407
Range on HMM: 19-351/351
Sequence Identity: 24% (84 aa)

GKWRG----------------------------TKVFVKVISID--TKTGDD------------------------------KLKEFINELSLALKLRHP
.||||                            ..| .|.. .|  | .  |                              .. || .|...  .|.||
AKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTID-NDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAFREFRHEVWIMSHLNHP

NVVQFLGAVTQSIPVMLVMEHLPKGDLQSYMKKKGK--------PLKPKKALKFALDIARGLNYVHEFKPEPVIHSNLKPSN-LL-RDKAG---------
|.|. .|   .  | ..||| .| |||......| .         ...   || ||.||.|..| | ..| |.|| .||. | || . ...         
NIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLKSPNILLWSSPQNHSPNYPNAH

-HLKITDFAFTK--YAFND--RQFVPDSGRYMAPELYR---CEDYDSKVDVFSFALIVQEMMEGV-PPFPKLG-------EEEVAKSYADGKRPPFK---
 . || ||  .   ..|    . .. .  ..||||  |    | |. |||..||..|  | . .  .||  .        .|.. .   .| ||...   
VCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHY

IKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKEVEK
 .|. ..  ..|||..||. ||.|||.| .| |  . 
CPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLK-Un_f-1.AA TK 169-405 15 6.9e-38 124.07 In-house 21-486 (486) Show / Hide 
Range on Protein: 169-405
Range on HMM: 21-486/486
Sequence Identity: 15% (74 aa)

GKWRG---------------------------TKVFVKVISIDTKTGDDKLKE--------------FINELSLAL--KLRHPNVVQFLGAVTQS-----
|.|||                           |.| ||..  .. . ..  ..              . .|... .  ...|||.|...|..||.     
GEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPKPC

-------IPVMLVMEHLPKGD----LQSYMKKKGKP----------------------------------------------------------------
        |.|.|||. |.||    |..| .|. ..                                                                
FEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLLQM

-----------LKPKKALKFALDIARGLNYVHEFKPEPV----IHSNLKPSNLLRDKAGH-----------LKITDFA--------FTKYAFNDRQFVPD
           | ..  | ....||.|. | |. . |      .| .|   | | .. ..            ||.||          ...  .|   . .
AWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRK

SGRY-----------------------------MAPELYRCED---------YDSKVDVFSFALIVQEMME-G-VPPFPKLGE---------EEVAKSYA
|...                             ||||  .            . .| ||.||   . |..  | .|. . .           .|| .   
SSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLR

DGKRPPFK------------IKPRYYP--------------EGLKDLIEKCWHDDPRKRPSFRTICKEV
.| |. ..             .| . |              | . ||. .||| ||..||.|... .. 
RGGRL-CRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MLK-Un_f-1.AA TKL-ciliate2 170-406 33 1.5e-35 115.74 In-house 19-273 (273) Show / Hide 
Range on Protein: 170-406
Range on HMM: 19-273/273
Sequence Identity: 33% (86 aa)

KWRGTKVFVKVISIDTKTGDDKLKEFINELSLALKLRHPNVVQFLGAVTQSIPVMLVMEHLPKGDLQSYMKKKGKPLKPKKALKFALDIARGLNYVHEFK
||| . | ||   .|    ......|.||      |||||.| |||| |..    ..||   .| | | .. .  .|      . |||||||  |.|  .
KWREIVVAVKKFKMDHDN-QQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRRRIALDIARGVHYLHSSN

PEPVIHSNLK--------------------PSNLLRDKAGHLKITDFAFTKYAFNDRQFVPDSGRY--MAPELYRCEDYDSKVDVFSFALIVQEMMEGVP
| |.||  ||                      |.| |     |.||| .|.   .|       | |  ||||  .   |  | ||||...|. |.    |
P-PIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFYYTEKADVFSYSIILWEIASREP

PFPKLGEEEVA-KSYADGKRPPFKIKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKEVE
|.     . || |   .  ||     |.  |  . ||...|| ..   ||||  | ||.|
PYRNKKGDVVAEKVMCNNLRP---TIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase MLK-Un_f-1.AA STE 173-397 18 6.3e-34 117.23 In-house 39-347 (359) Show / Hide 
Range on Protein: 173-397
Range on HMM: 39-347/359
Sequence Identity: 18% (59 aa)

GTKVFVKVISIDTKTG--------------DDKLKEFINELSLALKLR--HPNVVQFLGAVTQSIP-------VMLVMEHLPKGDLQSYMKKKGKPLKP-
|. . .|........               .........|...  |..  |||.|...|.  .  .       . ..||... | | . .|.|....|| 
GEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPL

------------KKALKFALDIARG-LNYVHEFKPEPVIHSNLKPSNLLRDKAGHLKITDFAFTKYAFN-------------------DRQFVPDSGRYM
            .   ... .| .| |.| |. .   .||  .||.| |       |..|| . .   .                    |. .  .  .|
NHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WM

APELYRCED------YDSKVDVFSFALIVQEMMEGVPPFPKLGEEEVAKSYADG---------------KRPPFKIK----------------PRYYPEG
|||  ....      || |.|. |. . . || .| ||. ..   ..    ...               . ||.. .                |. . . 
APEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPE

LKDLIEKCWHDDPRKRPS
.|| |.||   ||.|||.
FKDFINKCLQKDPNKRPT
S_TKc MLK-Un_f-1.AA S_TKc 151-403 25 1.7e-33 118.5 SMART 1-220 (231) Show / Hide 
Range on Protein: 151-403
Range on HMM: 1-220/231
Sequence Identity: 25% (69 aa)

YEIDRE---------ELSVSSEDSFTIGKWRGTKVFVKVISIDTKTGDDKLKEFINELSLALKLRHPNVVQFLGAVTQSIPVMLVMEHLPK--GDLQSYM
||| |.          . .  .         | .| .|.|.          . ...|...  | .|||.|.....      . .|||...   ||| .|.
YEILRKIGKGAFGKVYKCRHKK--------TGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI

KKKGKP-----LKPKKALKFALDIARGLNYVHEFKPEPVIHSNLKPSNLLRDKAGHLKITDFAFTKYAFNDRQFVPDSGRYMAPELYRCEDYDS-KVDVF
||.|..     . .  | ...  |...|.| |. .   .||  |||.|.| |.  |.||.|| . .        .  .  |||||.     |.  |.|. 
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWW

SFALIVQEMMEGVPPFPKLGEEEVAKSYADGKRPPFKIKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICK
|.  |. ||. | ||||     .... .   .           .. .||.|.||.. ||.|||.   . .
SCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase MLK-Un_f-1.AA TK-Unique 193-405 27 1.6e-32 109.53 In-house 48-294 (294) Show / Hide 
Range on Protein: 193-405
Range on HMM: 48-294/294
Sequence Identity: 27% (69 aa)

KEFINELSLALKLR-HPNVVQFLGAVTQS-IPVMLVMEHLPKGDLQSYMKKKGKP-------------------------LKPKKALKFALDIARGLNYV
..| .|...  .|  |||.||.||. | | .|.|..||..|.|.||.| ......                         ..||  . || .||.|..| 
QDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYL

HEFKPEPVIHSNLKPSNLLRDKAGHLKITDFAFTK-------YAFNDRQFVPDSGRYMAPELYR--CEDY-DSKVDVFSFALIVQEMM-EGVPPFPKLGE
..  .. ..| .|  .| |    . .||.|| ...       |. ...|. . . |.||||  .   . |  .| || ||. .  |..  | .|.|..  
ASQ-RKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQG-RIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPW

EEVAKSYADGKRPPFKIKPRYY-PEGLKDLIEKCWHDDPRKRPSFRTICKEV
... .   ||.|.|   .| .. .. .  |.. ||...| .|||||.| .. 
KDIMECIRDGYRMP---QPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase MLK-Un_f-1.AA Dicty4-Unclassified 169-405 29 5e-32 106.95 In-house 18-263 (263) Show / Hide 
Range on Protein: 169-405
Range on HMM: 18-263/263
Sequence Identity: 29% (74 aa)

GKWRGTKVFVKVI-SIDTKTGDDKLKEFINELSLALKLRHPNVVQFLGAVTQSIP------VMLVMEHLPKGDLQSYMK----KKGKPLKPKK--ALKFA
| |.|  | || . .   |  .. ...|  |  .   . ||| |.  |.     |       . ||| ..|| |          . .|.|      .|.|
GNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN--PRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYA

LDIARGLNYVHEFKPEPVIHSNLKPSNLLRDKAGHLKITDFAFTKYAFNDRQFVPDS--GRYMAPELYRCEDYDSKVDVFSFALIVQEMMEGVPPFPKLG
.|||.|. . |      .||  .| ||.| ||    || ||       .           .  .||  . | | .| ||.|.|..  |.. |  |.    
FDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEPYQEIQ

-EEEVAKSYADGKRPPFKIKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKEV
   ..| | .| |  | || |   .  .| ||  |||.||.|||..  | .  
SIMNAARSVCDKKLRP-KI-PDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
TyrKc MLK-Un_f-1.AA TyrKc 164-405 26 1.4e-29 105.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 164-405
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

DSFTI------------GKWRGTKVFVKVISIDTKTGDDKLKEFINELSLALKL--RHPNVVQFLGAVTQS-------IPVMLVMEHLPKGDLQSYMKKK
 ..              |.|. ..| ||..  |.      ...|..|...  ||  .|||.|...|..||.        |.|.|||. |.|||..| .|.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GKPLKPKKALKFALDIARGLNYVHEFKPEPVIHSNLKPSNLLRDKAGHLKITDFAFTKYAFND-------RQFVPD---SGR------YMAPELYRCEDY
.. |..|. |.|...||.| .| |.    ..||  |   | | .. .. ||.||  ...  .|          ..    .|.       ||||  .   .
RPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DSKVDVFSFALIVQEMME-GVPPFPK-----LGEEEVAKSYADGKRPPFKIKPRY--------YPEGLKDLIEKCWHDDPRKRPSFRTICKEV
 .| ||.||     |..  | .| |      .  .|| .   .|.|.|   .| .         |. . .....||| || .||.|..|... 
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMP---QPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MLK-Un_f-1.AA Dicty4 169-296 36 5.3e-28 90.62 In-house 18-158 (277) Show / Hide 
Range on Protein: 169-296
Range on HMM: 18-158/277
Sequence Identity: 36% (52 aa)

GKWRGTKVFVKVI-SIDTKTGDDKLKEFINELSLALKLRHPNVVQFLGAVT--QSIP--VMLVMEHLPKGDLQSYMKK------KGKPLK---PKKALKF
|.|||..| ||.  .  ..   . |.|| .| ..  |.||||...|.|| |   |.|  .. |.| .|||.| |   .      . ..|     |.|.. 
GTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRM

ALDIARGLNYVHEFKPEPVIHSNLKPSNLLRDKAGHLKITDF
|.|.|||.|. |.  |  .||  ||..||| ||    |..||
AFDAARGMNWLHCCNPV-IIHRDLKSHNLLVDKNWRVKVCDF
Kinase MLK-Un_f-1.AA Pkinase_Tyr 169-264 29 1.6e-26 90.45 Pfam 18-126 (270) Show / Hide 
Range on Protein: 169-264
Range on HMM: 18-126/270
Sequence Identity: 29% (33 aa)

GKWR------GTKVFVKVISIDTKTGDDK--LKEFINELSLALKL-RHPNVVQFLGAVT-QSIP--VMLVMEHLPKGDLQSYMKKK---GKPLKPKKALK
|.|.      ...| ||..    .. ..   ...|..|...  .| .|||.|...|..| |. |  ...|||. |.||| .| .|.   ..||..|  |.
GTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQ

FALDIARGLNY
....||.|..|
MCWQIAKGMEY
Kinase MLK-Un_f-1.AA MLK 169-296 27 1.9e-25 85.29 In-house 18-177 (291) Show / Hide 
Range on Protein: 169-296
Range on HMM: 18-177/291
Sequence Identity: 27% (45 aa)

GKWRGTK-----VFVKVISIDT----KTG--DDKLKEFINELSLALKLRHPN----VVQFLGAVTQSIP-VMLVMEHLPKGDLQSYM---KKKGK-----
|.||..      | || . ...    .|.  ..........|.   .|.|||    ..||.|. .|. . . .||| ...| | ..    ..|.      
GRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLR---ILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHN

-----PLKPKKALKFALDIARGLNYVHEFKPEPVIHSNLKPSNLLRD------KAGHLKITDF
       ..  |...||..|||..| |. .| |.||  ||..|.| |      . |.|||.||
QKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDF
Pkinase MLK-Un_f-1.AA Pkinase 168-296 27 2.2e-24 87.27 Pfam 17-156 (293) Show / Hide 
Range on Protein: 168-296
Range on HMM: 17-156/293
Sequence Identity: 27% (40 aa)

IGKWRGTK--VFVKVISIDTKTGDDKLKEFIN--ELSLALKLRHPNVVQFLGAVTQSIPVMLVMEHLPKG----DLQSYMK-KKGKPL--KPKKALKFAL
.....||   | ||.|. . .. ..|... ..  |... ..|.|||.|....... .  . .|||....|    || .|.. ......   .. . ....
KCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMY

DIARGLNYVHEFKPEPVIHSNLKPSNLLRDKAGHL----KITDF
 |.|||.| |.     .||  |||.|.| |. ||.    ||.||
QILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDF
Kinase MLK-Un_f-1.AA Pkinase 314-405 26 2.8e-20 72.77 Pfam 176-293 (293) Show / Hide 
Range on Protein: 314-405
Range on HMM: 176-293/293
Sequence Identity: 26% (32 aa)

RYMAPELYR-CEDYDSKVDVFSFALIVQEMMEGVPPFPKL----GEEEVAKSYADGKRPPFKIKPRYY--------------------PEGLKDLIEKCW
.|||||. | ...|..|||..|. .|. ||. | ||||      .  .  . ..  ..||..    .                     .| .||.|..|.
WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL

HDDPRKRPSFRTICKE--V
. || |||... |..   .
CKDPKKRPTAEQILQHPWF
Kinase MLK-Un_f-1.AA Dicty4 315-407 31 5e-20 63.65 In-house 183-277 (277) Show / Hide 
Range on Protein: 315-407
Range on HMM: 183-277/277
Sequence Identity: 31% (31 aa)

YMAPELYRCEDYDSKVDVFSFALIVQEMMEGVPPFPKLGEE--EVAKSYAD-GKRPPFKIKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKE--VEK
.||||  . . |..|.||.||...  |.  .  |..|.. .  ... . .. . |||    | . |  .|.||..||. || .||||  | ..   | 
WMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPI---PDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLK-Un_f-1.AA MLK 314-405 35 1.1e-18 61.48 In-house 198-291 (291) Show / Hide 
Range on Protein: 314-405
Range on HMM: 198-291/291
Sequence Identity: 35% (34 aa)

RYMAPELY---RCEDYDSKVDVFSFALIVQEMMEGVPPFP-KLG-EEEVAKSYADGKRPPFKIKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKEV
..||||     ||| |. |.||.|....  ||. .  |.   .   .  ..  . |.|||  .     ||..| |...||..||.|||||| | .. 
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPST---CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MLK-Un_f-1.AA Pkinase_Tyr 314-405 35 1.7e-11 39.55 Pfam 179-270 (270) Show / Hide 
Range on Protein: 314-405
Range on HMM: 179-270/270
Sequence Identity: 35% (34 aa)

RYMAPE--LYRCEDYDSKVDVFSFALIVQEMME-GVPP-FPKLGEEEVAKSY-ADGKRPPFKIKPRYYPEGLKDLIEKCWHDDPRKRPSFRTICKEV
. ||||   |.   . .| || ||     |..  |  | .| .  ||| .    || | |    |.. |. . ||. .||| || .||.|. |  . 
KWMAPECINYGK--FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC---PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL