Gene LmjF15.1200 (L.major)

LmjF15.1200

Species: L.major
Alias: LmjF15.1200, LmajK198
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF15.1200.AA Protein None 2689 None Fasta, JSON
LmjF15.1200.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of LmjF15.1200.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CNMP LmjF15.1200.AA cNMP 359-477 19 4.7e-15 57.25 SMART 1-123 (123) Show / Hide 
Range on Protein: 359-477
Range on HMM: 1-123/123
Sequence Identity: 19% (25 aa)

SFSSLEADTLESVLKAMDKEVHAAGAAILEQGQATTEKLYLVGEGTCEAIKN---------GKSLGPLQPGGTFGELELMYKQAMCAATVRCVTRCVLYT
 |..|....|.... .|  .. .||  |..||.. .. .|.. .|. . .|          .. .| |.||  |||| |.      ..|. ....|.. |
MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDH-FYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL----RRPRTAAARACCECCT

LDEASYHRAVMTSALQKRRKFEKLTTNV
..  .... .. .. ....  . | . .
IWRIDFQHFMQQLQQHPQHMYRMLQQLA
CNMP_binding LmjF15.1200.AA cNMP_binding 377-464 22 2.5e-14 51.82 Pfam 1-91 (91) Show / Hide 
Range on Protein: 377-464
Range on HMM: 1-91/91
Sequence Identity: 22% (21 aa)

KEVHAAGAAILEQGQATTEKLYLVGEGTCEAIKNGKSLG-----PLQPGGTFGELELMYKQAMCAATVRCVTRCVLYTLDEASYHRAVMTSAL
..  ..|  |..||..  . .|.| .|... .| ...        |.||  |||..|.. |. ..|||. .|.|... .. .. .. ....  
VRHYKKGEVIFHQGDP-CDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQNPRTATVVALTDCECWRIPREDFRQLMQQHPE
CNMP LmjF15.1200.AA cNMP 479-597 24 2.7e-22 81.29 SMART 1-123 (123) Show / Hide 
Range on Protein: 479-597
Range on HMM: 1-123/123
Sequence Identity: 24% (30 aa)

FLRCLPDFERMKIAEALETRVYQRGKTIIRFGSPGNYMHFIIEGEVKVVGR-----NSGRRVEVVRLRDGDVVGELEFLFNHLTVADVVATSREVRTACI
... |.. |. ......|.|.|. | .|.| | ||... .|..|.|.|. .     ..||...| .|. ||..||| .| .  ..|...| .. ..   |
MFKNLDEQELRELCDHMEPRHYPAGEYIFRQGDPGDHFYIIVSGWVRVYKTRVQHMEDGREQIVGFLGPGDFFGELALL-RRPRTAAARACCECCTIWRI

SREHFELIVGPIQDRLKEFVATSS
...||. ... ........ .. .
DFQHFMQQLQQHPQHMYRMLQQLA
CNMP_binding LmjF15.1200.AA cNMP_binding 497-587 26 6.6e-19 67.55 Pfam 1-91 (91) Show / Hide 
Range on Protein: 497-587
Range on HMM: 1-91/91
Sequence Identity: 26% (25 aa)

TRVYQRGKTIIRFGSPGNYMHFIIEGEVKVVGRNSGRRVE-VVRLRDGDVVGELEFLFNH-LTVADVVATSREVRTACISREHFELIVGPIQD
.| |..| .|.. | |.........|.|||.  ... |.  . .|. ||..||.... |.   .|.|||   ... ..|.||.|. ..    .
VRHYKKGEVIFHQGDPCDHFYIVLSGKVKVYK-DEDGREQILGFLGPGDFFGEMALFTNQNPRTATVVA-LTDCECWRIPREDFRQLMQQHPE
PAS LmjF15.1200.AA PAS 717-752 36 1e-06 24.53 Pfam 13-48 (120) Show / Hide 
Range on Protein: 717-752
Range on HMM: 13-48/120
Sequence Identity: 36% (13 aa)

VAVLALREDGLIMYWNSVLERLTSYSAGEAVGQNIY
...... ||| |.|||.  ||.. .|. |..|...|
DPIFVWDEDGWILYWNRAAERMFGWSREEVMGKMLY
PAS LmjF15.1200.AA PAS 706-772 18 8.6e-05 23.16 SMART 1-68 (68) Show / Hide 
Range on Protein: 706-772
Range on HMM: 1-68/68
Sequence Identity: 18% (13 aa)

RFPFAPITGKEVAVLALREDGLIMYWNSVLERLTSYSAGEAVGQNIYSFLLSERE--QQCMYKAINAAR
..  | .    ...... .|| |.|||   .... ||  | .||... ..  | .  ....   ... .
ERYRAILENMPDGIWVWDHDGRITYWNPAACQMFGYSPEELIGQSWWDLIHPEDRNLERFQE-HQRLQQ
Kinase LmjF15.1200.AA STE 1297-1565 23 1e-77 264.49 In-house 1-359 (359) Show / Hide 
Range on Protein: 1297-1565
Range on HMM: 1-359/359
Sequence Identity: 23% (87 aa)

WRHGALLGKGSSGEVYEAYDVL---------------TGGKMAVKEMRVGNND----------------AKIEQFVQEVSTMCNLQ--HPNIIHYFYCEE
|..   .|||..|.|| |...                ||  ||.|.|.. |..                 ...|. .|...| ...  ||||..|. |..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----SKEQKVIRVFMEFAGGGTLQSLLKTK--------------GRLEYAELRALLRDVVEG-LAYIHSQHYVHGDIKTANVLLSNDGKCKIGDFGTAR
     .|.   . ..||. .||.| ...|.|              .|..  .... .|....| |.|.||.|..| ||| ||.||     .|. |||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

TVNE-----------------GELLYVMQGSPLYMSPECMSAGEEDEDGNRIGYSFPSDIWSLGCVAMEMATNKPPFAHIKTIKGPAGLTNFITSLT---
 ...                 ..  . . |.| .|.|| .. ....    . ||.. .|||||||...|||| |||..  .  .     .. . .     
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R--DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

-------DVPDLSP-----------------LFKCHPSIVEFVSACLNPDPSQRATAQELLQ--MCLF
       . | | .                   |. |.  .|.. ||. ||..|.||..||.     .
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF15.1200.AA S_TKc 1297-1565 25 6.7e-76 259.39 SMART 1-231 (231) Show / Hide 
Range on Protein: 1297-1565
Range on HMM: 1-231/231
Sequence Identity: 25% (74 aa)

WRHGALLGKGSSGEVYEAYDVLTGGKMAVKEMRVGNNDAKIEQFVQEVSTMCNLQHPNIIHYFYCEESKEQKVIRVFMEFAGG--GTLQSLLKTKGR---
.. . ..|||. |.|| .... || ..|.|...        |.. .|.. . . .||||...... ..   . . ..||...|  |.| ...| .||   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LEYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGKCKIGDFGTARTVNEGELLYVMQGSPLYMSPECMSAGEEDEDGNRIGYSF-PSDIW
   .   . | ... ....|.|.||.. .| |.| .|.||..    ||.||| || .      . . |.| ||.|| .            ||.. ..|.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL------------GYGKCKCDWW

SLGCVAMEMATNKPPFAHIKTIKGPAGLTNFITSLTDVPDLSPLFKCHPSIVEFVSACLNPDPSQRATAQELLQ-------MCLF
|.||.  ||.. .|||        .. . . |                |.  .|.. ||. ||..| || |.||       .  |
SCGCILYEMLCGYPPFP------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF15.1200.AA Pkinase 1297-1565 24 5.8e-64 223.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 1297-1565
Range on HMM: 1-293/293
Sequence Identity: 24% (76 aa)

WRHGALLGKGSSGEVYEAYDVLTGGKMAVKEMRVGNNDAKIEQFVQ-----EVSTMCNLQHPNIIHYFYCEESKEQKVIRVFMEFAGGG----TLQSLLK
.. |  .|.||.|.||..... || . |||....   ..| .. ..     |.. | .|.||||. .... |.   . | . ||...||     | ....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIS

--TKGRL--EYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGKC----KIGDFGTART--VNEGELLYVMQGSPLYMSPECMSAGEEDEDGNR
   .|..  .. |..  .. ...||.|.||.  .| |.| .|.|..|.| .    ||.||| |.      .. ...  |.| ||.||            .
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR--------GG

IGYSFPSDIWSLGCVAMEMATNKPPFAHI-KTIKGPAGLTNFITSLTDVPDLSPLFKCH-------------------PSIVEFVSACLNPDPSQRATAQ
 .|. ..|.||.||.  ||.. .||| .   ...    .  .   .   .. .   .|                    ..  .|.. ||..||..| ||.
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

ELLQMCLF
..||   |
QILQHPWF
Kinase LmjF15.1200.AA STE11 1297-1504 33 3.7e-63 216.12 In-house 1-239 (303) Show / Hide 
Range on Protein: 1297-1504
Range on HMM: 1-239/303
Sequence Identity: 33% (81 aa)

WRHGALLGKGSSGEVYEAYDVLTGGKMAVKEMRVGNNDA-------KIEQ------FVQEVSTMCNLQHPNIIHYFYCEESK-EQKVIRVFMEFAGGGTL
|. |...|||. | || ...| ||  ||||.....||.        ....      . .|.. | .|.|.||. |. |. .. ... . .|||.  ||.|
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

QSLLKTK-GR--LEYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGK-CKIGDFGTARTVN----EGEL-------LYVMQGSPL--------
 |.|..| |.  .. .. |   ... |||.| ||.. .| ||| ||.||  ||  ||..|||.|. ..    ...        . .|.|.|         
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

YMSPECMSAGEEDEDGNRIGYSFPSDIWSLGCVAMEMATNKPPFA
.|.||  . .  |      ||. ..|||||||.  |||| |||..
WMAPEVIKQEGRD------GYGRKADIWSLGCTVIEMATGKPPWH
Kinase LmjF15.1200.AA STE11-Unclassified 1297-1504 31 1.3e-51 177.8 In-house 1-239 (308) Show / Hide 
Range on Protein: 1297-1504
Range on HMM: 1-239/308
Sequence Identity: 31% (78 aa)

WRHGALLGKGSSGEVYEAYDVLTGGKMAVKEMRVGNND-------AK-IEQFVQEVSTMCNLQHPNIIHYFYCEESKEQKVIRVFMEFAGGGTLQSLLKT
|  |...|||| |.|| . .. ||  ||||........        . |... .|.... .| |.||. |  ||..|... | .|||   || . |.|. 
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

KGRLEYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGKCKIGDFGTAR-------------------TVNEGELLY-------VMQGSPL---
 |... .  .   ... ||||| ||.. .| ||| ||.|.  || ||. |||.|.                    ... . ..        |||.|    
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

YMSPECMS-AGEEDEDGNRIGYSFPSDIWSLGCVAMEMATNKPPFA
.|.||  .   ..       |..  ||||||||.  |||| |.|..
WMAPEVIKNSTQT-------GHCRKSDIWSLGCTVIEMATGKHPWS
Kinase LmjF15.1200.AA CAMK 1302-1565 17 3.9e-50 159.33 In-house 1-425 (425) Show / Hide 
Range on Protein: 1302-1565
Range on HMM: 1-425/425
Sequence Identity: 17% (74 aa)

LLGKGSSGEVYEAYDVLTGGK------------MAVKEMR---VGN------------------------NDAKIEQFVQEVSTMCNLQ-------HPNI
 ||.|| |.|..... .|.||             |.| .    . .                        .. . ... .|.. | .||       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IHYFYCEESKE-----------------QKVIRVFM---EFAGGG----TLQSLLKTK---------------GRLEYAELRALLRDVVEGLAYIHSQHY
|. .   |...                 .| .  .|   |.. ||     | . .. .               ||.. .| | . | ......|.||.. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHGDIKTANVLLSND-----------------GKCKIGDFGTARTVNE------------------------GELLYVMQGSPLYMS-PECMSA--GEED
|| |.|  |.||...                 .. || ||| |. ...                        |.... . |.| ||. ||  .   . . 
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

EDGN-----RIGYSFPSDIWSLGCVAMEMATNKPPFAHIKTIKGPA------GLTNFITSLTDVP-DLSPLFKCHPS----------------------I
.  |     . .|....|.||.|..   | . .||| . .    .        . .     .    |  | .  ..|                       
Q--NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

VEFVSACLNPDPSQRATAQELLQMCLF
  ... .|..||..|.|... |.   .
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF15.1200.AA TKL 1303-1563 19 8.3e-50 171.78 In-house 1-364 (364) Show / Hide 
Range on Protein: 1303-1563
Range on HMM: 1-364/364
Sequence Identity: 19% (72 aa)

LGKGSSGEVYEA-YDVLTGGK--------MAVKEMRVGNNDA--------------------------KIEQFVQEVSTMCNLQHPNIIHYFY-CEESKE
.|.|..|||| . .   .| |        .||| ... |.|                             .....|.  | .|.||||...   | ... 
IGSGGFGEVYKGKWRGWGG-KCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

----------QKVIRVFMEFAGGGTLQSLLKTKGRLEYAELRALLRDVVEGLAYIHSQH--------YVHGDIKTANVLLSNDGK--------------C
          .. .   ||.. ||.| ..|          .  . .|.  |..| ||..         .| |.|..|.|. ....              |
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KIGDFGTARTVNEGE--------------------LLYVMQGSPLYMSPECMSAGEEDEDGN-------RIGYSFPSDIWSLGCVAMEMATNKPPFAHIK
||.|||..|.... .                     ..   |.| .|.||..   ..... .          ||  .|..| | |  |..| ..|.....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

--------------TIKGPAGLTNFIT-----SLTDVPDLSPLFKCHPSIVEFVSACLNPDPSQRATAQELLQMC
               . .  ||   |       .      .|   | ||. .    | ..||..| ..||.|.  
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LmjF15.1200.AA STE20 1297-1504 31 7e-48 165.4 In-house 1-228 (288) Show / Hide 
Range on Protein: 1297-1504
Range on HMM: 1-228/288
Sequence Identity: 31% (72 aa)

WRHGALLGKGSSGEVYEAYDVLTGGK----MAVKEMRVGNND---AKIEQFVQEVSTMCNLQHPNIIHYFYCEESKEQ--KVIRVFMEFAGGGTLQSLLK
.     .|.||.|.|| ||.. || .     |.| | . . |    ..|  ..|.| | ...||||..|. .   .      . . ||. |||.|. ..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---TKG------RLEYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGKCKIGDFGTARTVNE-----GE-LLYVMQGSPLYMSPECMSAGEED
   ..|      ... ..  . .|.|..||.|.||.|..| ||| .|.||. ||..|. ||| .  ...            . |.| .|.|| ..     
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQC----

EDGNRIGYSFPSDIWSLGCVAMEMATNKPPFA
..|.. || . .||||||  |.|||. .||..
MEGPDKGYDYKCDIWSLGITAIEMAEGEPPYF
Kinase LmjF15.1200.AA MEKK2 1297-1504 36 1.7e-47 164.1 In-house 1-207 (262) Show / Hide 
Range on Protein: 1297-1504
Range on HMM: 1-207/262
Sequence Identity: 36% (79 aa)

WRHGALLGKGSSGEVYEAYDVLTGGKMAVKEMRVGNNDAKIEQFV----QEVSTMCNLQHPNIIHYFYCEESKEQKVIRVFMEFAGGGTLQSLLKTKGRL
|| | |||.|  | ||  ||| ||  .||| ... ....   . |    .|.  . ||||. |. |. | . ...|.. .|||.  || ..  ||  | |
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGAL

EYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGKCKIGDFGTARTVN----EGELLYVMQGSPLYMSPECMSAGEEDEDGNRIGYSFPSDIWS
  .  |   | ..||..|.|... || ||| ||.|    |  |.|||| .. .     ..  .  . | | .|||| .. ||        ||    |.||
TETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVIN-GE--------GYGRKADVWS

LGCVAMEMATNKPPFA
.||  .|| |.|||.|
IGCTVVEMLTEKPPWA
Kinase LmjF15.1200.AA Ciliate-E2 1302-1565 20 1.3e-45 154.59 In-house 6-365 (365) Show / Hide 
Range on Protein: 1302-1565
Range on HMM: 6-365/365
Sequence Identity: 20% (76 aa)

LLGKGSSGEVYEAYDVLTGGKMA----------------VK---EMRVGNNDAKIEQFVQEVSTM----------------CNLQHPNIIHYFYCEESKE
..|.|. | ||.. . ... . |                ||        ..  .|||. || . |                 .|.||||| ...| ..| 
KIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKD

QKVIRVFMEFAGGGTLQSLLK---TK--------GRLEYAELRALLRDVVE---------------GLAYIHSQH-YVHGDIKTANVLLSNDGKCKIGDF
.. |   ||.. ||.|....|   .|        ...   | . . . ...               .| |.||..  .| |||  |.|.     .|| ||
DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDF

GTARTVNE-----------GELLYVM----------------------QGSPLYMSPECMSAGEEDEDGNRIGYSFPSDIWSLGCVAMEMATNKPPFAHI
|... ...           .....                         |.| ||.||  . ...| . .. ||.. .||||||..  || ..||||   
GLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---

KTIKGPAGLTNFITSLTDVPDLS----------------PLFKCHPSIVEFVSA----CLNPDPSQRAT-AQELLQMCLF
           ..  .    |..                  .|. ..   . .     .|. ||..| | ....|.   |
-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF15.1200.AA ULK 1303-1565 24 1.9e-42 145.97 In-house 7-329 (329) Show / Hide 
Range on Protein: 1303-1565
Range on HMM: 7-329/329
Sequence Identity: 24% (82 aa)

LGKGSSGEVYEAYDVLT----GGKMAVKE-----MRVGNNDAK----IEQFVQEVSTMCNL--------QHPNIIHYFYCEESKEQKVIRVFMEFAGGGT
||||| | ||..... |    . | |.|      |.  ||..     .... .|. .|  |        .||||. .. . |..  . |  .||.  ||.
LGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGD

LQSLLKTKGR----------LEYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSN-DGK-----------CKIGDFGTARTVNEG----ELLYVMQ
|....|....          |.  | .  ... ..|. ..|.. ..| ||| .|.|..| ..|           .||.||| |..|...    .... . 
LEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCV

------GSPLYMSPECMSAGEEDEDGNRIGYS-FPSDIWSLGCVAMEMATNKPPFAHIKTIKGPAGLT-NFITSLTDVPDLSP--------LFK------
      |.||||.|.  .     . | .. |. . .|||||||.  || ..||||        .  .  ..|..| . |. .|         |.      
NEKRLCGTPLYMAPQILQ-----GQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFY----AW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDP

-CHPSIVEFVSACLNPDPSQRATAQELLQMCLF
 . | . .. . .|  |...| . .||... .|
QISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase LmjF15.1200.AA STE-Unique 1365-1565 24 7.7e-39 135.36 In-house 364-616 (616) Show / Hide 
Range on Protein: 1365-1565
Range on HMM: 364-616/616
Sequence Identity: 24% (64 aa)

KEQKVIRVFMEFAGGGTLQSLLKTKGR---------LEYAELRALLRDVVEGLAYIHSQH--YVHGDIKTANVLLSNDG-----KCKIGDFGTARTVNEG
|||     |||.  .|||| ..|  |          ..  |   ... ..||| |.||||   .|.|.| .|.....||     | ||.|||.| .  ..
KEQNWVWIFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPD

---------------------------------------ELLYVMQGSPLYMSPECMSAGEEDEDGNRIGYSFPSDIWSLGCVAMEMATNKPPFAHIKTI
                                         .  . | | ||.||  .     ...   .|.  .|||||||. ..|..  ||. .   .
HFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINC----RNQINNPYDTKVDIWSLGCMCFHMCCGCPPWHQRYHM

KGPAGLTNFITSLTD-VPDLSPLFKCHPSIVEFVSACLNPDPSQRATAQELLQMCLF
.  . . . |...    |.  .  || |  ..|  .||...|..|..| .||.  . 
QAYIEMCIHIHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase LmjF15.1200.AA Pkinase_Tyr 1303-1564 25 3.1e-34 116.56 Pfam 7-270 (270) Show / Hide 
Range on Protein: 1303-1564
Range on HMM: 7-270/270
Sequence Identity: 25% (71 aa)

LGKGSSGEVYEAYDV----LTGGKMAVKEMRVGNNDAK--IEQFVQEVSTMCNL-QHPNIIHYFYCEESKEQK-VIRVFMEFAGGGTLQSLLKT----KG
||.|. ||||...       |. . ||| .. |  .    .| | .|...|..| .||||. .  .  ....   | . ||.. .| | . |..    |.
LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQ

RLEYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGKCKIGDFGTARTV-NEGELLYVMQG---SPL-YMSPECMSAGEEDEDGNRIGYSFPSD
.|   .|    ... .|..| .|....| |. . |.|.......||.||| ||.. |...  |...|    |   |.|||.. |.         ..  ||
PLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK---------FTTKSD

IWSLGCVAMEMAT-NKPP-FAHIKTIKGPAGLTNFITSL-TDVPDLSPLFKCHPSIVEFVSACLNPDPSQRATAQELLQMCL
.|| | .  |. |  . | .. ..          ..  .  |   . .  .|.. | .    | ..||..| | .|. . .|
VWSFGVLMWEIFTYGEQPTYPGMSNEE-------VYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI-HEQL
Kinase LmjF15.1200.AA TyrKc 1297-1563 22 1.2e-21 79.14 SMART 1-280 (280) Show / Hide 
Range on Protein: 1297-1563
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

WRHGALLGKGSSGEVYEAYDVLTGGKMAVKEMRVGNNDAKIEQFVQEVSTMCNL--QHPNIIHYFYCEESK-----EQKVIRVFMEFAGGGTLQSLLKTK
 . |  || |  ||||..       . ||| .. .     .| | .| . ||.|  .||||.  . .  ..     . . . . ||.. .| |.. |. .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GR-LEYAELRALLRDVVEGLAYIHSQHYVHGDIKTANVLLSNDGKCKIGDFGTARTVNEG------ELLYVMQ---GSP--L---YMSPECMSAGEEDED
.. |  ..|     .. .| .|.||....| |. . |.|..... .||.||| .| . ..      .  |...   |.   |    |.|||.        
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--------

GNRIG-YSFPSDIWSLGCVAMEMATN-KPPFAH-IKTIKGPAGLTNFITSLTDVPDLSPLFK--------CHPSIVEFVSACLNPDPSQRATAQELLQMC
  . | ... ||.|| | .  |. |. ..|    |.    .   .  |  . .   . .           |.. . .  . | . ||..| | .|. .  
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF15.1200.AA STE-Unique 1298-1358 21 5.1e-09 27.58 In-house 1-66 (616) Show / Hide 
Range on Protein: 1298-1358
Range on HMM: 1-66/616
Sequence Identity: 21% (14 aa)

RHGALLGKGSSGEVYEAYDVLTGGKMAVKEMRVGNND-AK----IEQFVQEVSTMCNLQHPNIIHY
..   .|.|| |.|. . .  ..  .|.|  .. .    .    ..... |. .|  | |.||. |
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKY
Kinase LmjF15.1200.AA STE20 1536-1561 46 4e-06 18.82 In-house 259-284 (288) Show / Hide 
Range on Protein: 1536-1561
Range on HMM: 259-284/288
Sequence Identity: 46% (12 aa)

PSIVEFVSACLNPDPSQRATAQELLQ
|.  .||. ||. ||..|.||..||.
PEFHDFVDKCLQKDPEKRPTASQLLK
Kinase LmjF15.1200.AA STE11 1540-1561 45 3.1e-05 15.18 In-house 278-299 (303) Show / Hide 
Range on Protein: 1540-1561
Range on HMM: 278-299/303
Sequence Identity: 45% (10 aa)

EFVSACLNPDPSQRATAQELLQ
.|.. |. .||. |.||..|||
DFLRHCFEHDPKKRPTANQLLQ
Kinase LmjF15.1200.AA STE11-Unclassified 1540-1561 45 0.000859 9.39 In-house 283-304 (308) Show / Hide 
Range on Protein: 1540-1561
Range on HMM: 283-304/308
Sequence Identity: 45% (10 aa)

EFVSACLNPDPSQRATAQELLQ
.| ..|.  ||. |.||..|||
DFLRKCFQIDPKKRPTANQLLQ