Gene LmjF25.1990 (L.major)

LmjF25.1990

Species: L.major
Alias: LmajK204, LmjF25.1990
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF25.1990.AA Protein None 576 None Fasta, JSON
LmjF25.1990.kin_dom Protein Kinase Domain None 373 None Fasta, JSON

Protein domain

Protein domains of LmjF25.1990.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF25.1990.AA STE11 5-377 26 5.6e-77 262.06 In-house 1-303 (303) Show / Hide 
Range on Protein: 5-377
Range on HMM: 1-303/303
Sequence Identity: 26% (106 aa)

VKLNRKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSV--PDEDDTELA-----AILSELACMREAQHTNLVEYYGARR-C--AIGIQIIMEYVSGGSL
 ..  ..| |  |.|| ...   | ..|.|. ..   .   .|  .   .     || .|.. |.  .| |.| |||. . .    .. |.|||..||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

DYVLT-RCGP--LRENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGR-CKLADFGVAKQVEVTTPTLPV------HAERGGQSMGKEEEGNF
  .|  . ||  . |.| | ||...||.|.|||.  .  |||.|.||||.  ||  ||||||| ||...  ...         |                
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHS-HGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNH----------------

PRHRNGGRQGYLQ-TAVGTPWYMAPEVINGGVEDDDEDDEGVELGNAFAVTIGGDANSSSFSEDWTSSGLAHTAPDASASPPPLYSSSNYYNPLKSIVKK
    .   .| .. . .||| .||||||...  |                                                                  
----CKSMTGTPYNSMMGTPMWMAPEVIKQEGRD------------------------------------------------------------------

GRLGARSVGYTTSADIWSVGVTVYEMVTGTKPFGADLTN-PSAVLFRIANCAASPPQLPADVH-VS---AELHSFLDLCFVYDKDLRATAAELLGHPWL
        ||...|||||.| ||.||.||  |. ..... . | .|.|.  . ..|..| ..  .|   .|.. ||..||..|.  |.||..|| ||..
--------GYGRKADIWSLGCTVIEMATGKPPW-HNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase LmjF25.1990.AA S_TKc 5-377 21 1.2e-73 251.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-377
Range on HMM: 1-231/231
Sequence Identity: 21% (84 aa)

VKLNRKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTELAAILSELACMREAQHTNLVEYYGARRCAIGIQIIMEYVSG--GSLDYVLTRCG
 .. ||.| |. |.|| . ..  |. ||||..                 |..|...... .| |.| .|.. .    . ..|||..|  |.|  .. ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

P------LRENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRCKLADFGVAKQVEVTTPTLPVHAERGGQSMGKEEEGNFPRHRNGGRQGYL
.      . | .|| |.. ...|| |.|.  . .|||.||.|||..   . |..|||.|.|.                                      
RHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------------------------------

QTAVGTPWYMAPEVINGGVEDDDEDDEGVELGNAFAVTIGGDANSSSFSEDWTSSGLAHTAPDASASPPPLYSSSNYYNPLKSIVKKGRLGARSVGYTT-
 | .||||||||||.                                                                                ||.. 
TTFCGTPWYMAPEVL--------------------------------------------------------------------------------GYGKC

SADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLPADVHVSAELHSFLDLCFVYDKDLRATAAELLG-------HPWL
..|.||.|...|||..|  ||     .. ... .|                | |. .|.. |...| . | || |.|        |||.
KCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF25.1990.AA STE 6-377 21 4.7e-72 245.69 In-house 1-359 (359) Show / Hide 
Range on Protein: 6-377
Range on HMM: 1-359/359
Sequence Identity: 21% (100 aa)

KLN-RKLGVGGRGVVYEGFDHA---------------RGHFVAIKELAYMEPSVPDED-----------DTELAAILSELACMREAQ--HTNLVEYYGAR
  . .|.| |. |.|| . .|                 | ..|||.. . . .  | .           ..|.  || |.  |.. .  | | |.|||. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

RCA-------IGIQIIMEYVSGGSLDYVLT-RCGPLR-------------ENVARAYTRDVLEA-LHYLHKTMHMCHRDVKPANILITPDGRCKLADFGV
            . |.|||..||||| ..  ..|...             |.. ....|..|.. |.|||.     |||.||||||.     .||.||||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLCDFGV

AKQVEVTTPTLPVHAERGGQSMGKEEEGNFPRHRNGGR-------QGYLQTAVGTPWYMAPEVINGGVEDDDEDDEGVELGNAFAVTIGGDANSSSFSED
..|.. . . .   .                   |.         |.  .| |||| .||||||... ..                              
CGQLTDSMANI-Q-S-------------------NN-IIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R----------------------------

WTSSGLAHTAPDASASPPPLYSSSNYYNPLKSIVKKGRLGARSVGYTTSADIWSVGVTVYEMVTGTKPF--GADLTNPSAVLFRIANCA---------AS
                                          . ||.|..||||.| |. ||.||  |.  . .. .  . .| .. ..           
------------------------------------------DKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGP

PPQLPADVH-----------------VSAELHSFLDLCFVYDKDLRATAAELLG--HPWL
||.|| ...                 .| |.. |...|...| . |.|| .||   ||..
PPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF25.1990.AA Pkinase 5-377 22 7.8e-64 223.18 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-377
Range on HMM: 1-293/293
Sequence Identity: 22% (90 aa)

VKLNRKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTELAAILSELACMREAQHTNLVEYYGARRCAIGIQIIMEYVSGG----SLDYVLT-
 .. ||.| |. |.||.. ..  |. ||.|.. .     ...| | . .  ||.. |.. .| | |..|.. .    | ..|||. ||    .|  ... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-RCGPL--RENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRC----KLADFGVAKQVEVTTPTLPVHAERGGQSMGKEEEGNFPRHRNGGR
 | |..   |.... | . .|..| |.|. |  .|||.||.||||  .| .    |..|||.|||..                                .
WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------------------------------Y-N

QGYLQTAVGTPWYMAPEVINGGVEDDDEDDEGVELGNAFAVTIGGDANSSSFSEDWTSSGLAHTAPDASASPPPLYSSSNYYNPLKSIVKKGRLGARSVG
.. ..| .|||||||||||.                                                                             . .
NS-MTTFCGTPWYMAPEVIR----------------------------------------------------------------------------GGQY

YTTSADIWSVGVTVYEMVTGTKPFGAD----LTNPSAVLFRIANCAASPPQL-----------------PADVHVSAELHSFLDLCFVYDKDLRATAAEL
|....|.||.|...|||..|  ||  .      .. ....||  .  . .                   .  . .| |. .|.. |. .|   | ||...
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI

LGHPWL
| |||.
LQHPWF
Kinase LmjF25.1990.AA STE11-Unclassified 5-159 37 3.5e-37 129.32 In-house 1-158 (308) Show / Hide 
Range on Protein: 5-159
Range on HMM: 1-158/308
Sequence Identity: 37% (60 aa)

VKLNRKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTEL--AAILSELACMREAQHTNLVEYYGAR--RCAIGIQIIMEYVSGGSLDYVLTR
..    .| |. | || ...   | |.|.|..     .  .||  .    .| .|.. ...  | | | |||.   .   .| |.|||..|||..  | .
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

CGPLRENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRCKLADFGVAKQVE
 |.. |.|.. ||...|| | |||.  .  |||.|.|||||  ||.|||.||| |||.|
YGCFDEMVIKKYTKQILEGLAYLHS-HGIIHRDIKGANILIDFDGICKLTDFGCAKQIE
Kinase LmjF25.1990.AA CAMK 10-213 20 5.3e-36 112.98 In-house 1-294 (425) Show / Hide 
Range on Protein: 10-213
Range on HMM: 1-294/425
Sequence Identity: 20% (64 aa)

KLGVGGRGVVYEGFDH-ARG-----------HFVAIKELAY----------------MEPSVPDE-----DDTELAAILSELACMREAQ-------HTNL
.|| |. |.|.....    |           . |||| .                  .. | ..      ..  .. ...|...|.  |       | |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VEYYGARR--------CAIG------------IQIIM---EYVSGG----S-LDYVLTR--------------CGPLRENVARAYTRDVLEALHYLHKTM
.  | .             .            . ..|   ||.|||      .||.  .              .| . |  || | | ...|.||.|.  
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

HMCHRDVKPANILITPD-----------------GRCKLADFGVAKQVEVTTPTLPVHAERGGQSMGKEEEGNFPRHRNGGRQGY--------LQTAVGT
  .||| || |||.. .                 .  |..||| |....     .      ||. | ..             | .        ..| .||
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN-------------Q-WTTPTEGQKMKTFCGT

PWYMA-PEVING
| ||| |||.||
PEYMAAPEVLNG
Kinase LmjF25.1990.AA MEKK2 6-156 39 6.1e-30 105.74 In-house 2-151 (262) Show / Hide 
Range on Protein: 6-156
Range on HMM: 2-151/262
Sequence Identity: 39% (60 aa)

KLNRKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTELAAILSELACMREAQHTNLVEYYGARRCAI--GIQIIMEYVSGGSLDYVLTRCGP
.. . || |  |.||  .|   |  .|.|    ..|. |.    |  |.  |.  ..  ||  .| |||  |      . | |||..|||.   |   |.
RRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQ-FDPDNPETRK-EVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGA

LRENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRCKLADFGVAK
| |.| | ||| .|| .||||  | . |||.| ||||    |  ||.||| .|
LTETVTRKYTRQILEGMHYLHDHM-IVHRDIKGANILRDSSGNVKLGDFGASK
Kinase LmjF25.1990.AA STE20 6-159 35 1.2e-29 104.84 In-house 2-168 (288) Show / Hide 
Range on Protein: 6-159
Range on HMM: 2-168/288
Sequence Identity: 35% (61 aa)

KLNRKLGVGGRGVVYEGFDH-ARGHF----VAIKELAYMEPSVPDEDDTELAAILSELACMREAQHTNLVEYYGARRCA----IGIQIIMEYVSGGSLDY
.| .|.| |. |.|| .  |   |      |||| . . .....     |.  |. |   |.. .| | |.|||.          . |.||| .||||  
ELLEKIGQGSYGKVYKA-YHKPTGEYCNQRVAIKKMNLEKCDNEQ---DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTD

VLT---RCG------PLRENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRCKLADFGVAKQVE
...   .||      |. |    . .|.||..|.|||. .|. |||.| .|||.| ||..|||||||. |..
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHS-NHIIHRDIKADNILLTEDGEVKLADFGVCAQLT
Kinase LmjF25.1990.AA ASK 11-163 35 5.7e-27 86.58 In-house 2-150 (254) Show / Hide 
Range on Protein: 11-163
Range on HMM: 2-150/254
Sequence Identity: 35% (56 aa)

LGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTELAAILSELACMREAQHTNLVEYYGARRCAIGIQIIMEYVSGGSLDYVL-TRCGPLR--EN
|| |  |.|| | |.     .||||       .|. |. .   .  |.|  .. .| |.|.| |.      ..| || | ||||  .| .. ||..  ||
LGKGTYGIVYAGRDMHTQVRIAIKE-------IPERDSRYVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNEN

VARAYTRDVLEALHYLHKTMHMCHRDVKPANILI-TPDGRCKLADFGVAKQVEVTTP
  . ||. .|| |.|||   .. |||.|  |.|. |  | .|..||| .| .   .|
TMNFYTKQILEGLKYLHE-NQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAGINP
Kinase LmjF25.1990.AA Dicty2 6-155 35 1.5e-25 85.99 In-house 2-153 (264) Show / Hide 
Range on Protein: 6-155
Range on HMM: 2-153/264
Sequence Identity: 35% (55 aa)

KLN-RKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTELAAILSELACMREAQHTNLVEYYGARRCAIGIQIIMEYVSGGSLDYVLTRCGPL
..   |.| |. |.|| | .   | |||||    |  ..   .   .  |  |    .  .| | | |..       . ||.||. .|||  .. . |..
QIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKT-KISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCF

RENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGR---CKLADFGVA
 |     | . ||. | |||      ||| | |||||| .|     ||||||||
PESLCCIYIYQVLKGLVYLHR-QGVIHRDIKAANILITKEGKSGVIKLADFGVA
Kinase LmjF25.1990.AA STE11-Unclassified 292-377 32 7e-25 85.13 In-house 214-308 (308) Show / Hide 
Range on Protein: 292-377
Range on HMM: 214-308/308
Sequence Identity: 32% (32 aa)

GYTTSADIWSVGVTVYEMVTGTKPFGADLTN--PSAVLFRIANCAASPPQLPADVH---------VSAELHSFLDLCFVYDKDLRATAAELLGHPWL
|.....||||.| ||.|| ||  |. ....|  ...... |.. . ..||.| .           .|.|.  ||..|| .|.  |.|| .|| ||..
GHCRKSDIWSLGCTVIEMATGKHPW-SNCQNDNFMWAIMKIVM-SNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTANQLLQHPFI
Kinase LmjF25.1990.AA Ciliate-E2 5-213 19 8.1e-25 82.11 In-house 1-261 (365) Show / Hide 
Range on Protein: 5-213
Range on HMM: 1-261/365
Sequence Identity: 19% (58 aa)

VKLNRKLGVGGRGVVYEGFDHARGHFVAIK-------------ELAYMEPSVPDEDDTELAAILSELACMREAQ----------------HTNLVEYYGA
 |...|.| |. |.||.. .   .. .|||             . . ..  .      .. .|..|.  ||| .                | |....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

RR--CAIGIQIIMEYVSGGSLDYVLT------------RCGPLRENVARAYTRDVLE---------------ALHYLHKTMHMCHRDVKPANILITPDGR
        | ..|||..||.| . .               ... |. .. ... .|.               ||.|||.  . .||| || |||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

CKLADFGVAKQVEV---------------------TTPTLPVHAERGGQSMGKEEEGNFPRHRNGGRQGYL-------QTAVGTPWYMAPEVING
.|..||| .|..                       .||.                               .       .| .||| |||||..||
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD----------------------------QIIQQNMFNTICGTPGYMAPEILNG
Kinase LmjF25.1990.AA MEKK15 6-156 33 1.4e-21 75.02 In-house 2-149 (264) Show / Hide 
Range on Protein: 6-156
Range on HMM: 2-149/264
Sequence Identity: 33% (50 aa)

KLNRKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTELAAILSELACMREAQHTNLVEYYGARRCAIGIQIIMEYVSGGSLDYVLTRCGPLR
|    || |  | || |     |  .|.|  .  | .   . . .   .  |   ..  .| |.| | |       ..| |..| |||.  .. | ||| 
KKGNILGKGAYGTVYCGL-TNTGQLIAVKQVELDE-IDKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPLD

ENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRCKLADFGVAK
| |   ||. .|.   |||    . |||.| .|... | |  || ||| ||
EMVFCKYTKQILQGVQYLHENC-VVHRDIKGNNVMLMPTGIIKLIDFGCAK
Kinase LmjF25.1990.AA STE20 289-377 35 3.8e-19 66.85 In-house 200-288 (288) Show / Hide 
Range on Protein: 289-377
Range on HMM: 200-288/288
Sequence Identity: 35% (32 aa)

RSVGYTTSADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLPA--DVHVSAELHSFLDLCFVYDKDLRATAAELLGHPWL
.  ||.. .||||.| |  ||..|  |.     .|  ..|.|..    || |      . | |.| |.|.| ..| . |.|| .|| ||..
PDKGYDYKCDIWSLGITAIEMAEGEPPYFDM--HPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase LmjF25.1990.AA CAMK 292-377 21 5.8e-19 57.09 In-house 310-425 (425) Show / Hide 
Range on Protein: 292-377
Range on HMM: 310-425/425
Sequence Identity: 21% (25 aa)

GYTTSADIWSVGVTVYEMVTGTKPFGAD-----------LTNPSAVLFRIANCAA--SPPQLPA---------DVHVSAE--------LHSFLDLCFVYD
.|. ..|.||.||  | |..|. || .|            .|..  . .| ..     ||...          . ..| |          ...  . ..|
YYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVD

KDLRATAAELLGHPWL
 . |.|... | |||.
PEKRMTIEQCLNHPWM
Kinase LmjF25.1990.AA Ciliate-E2 292-377 22 2.8e-18 59.36 In-house 272-365 (365) Show / Hide 
Range on Protein: 292-377
Range on HMM: 272-365/365
Sequence Identity: 22% (24 aa)

GYTTSADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLP----------------ADVHVSAELHSFLDL----CFVYDKDLRAT-AAE
||....||||.||. |||..|  ||             . .    . ..|                   ..| |   ..      ....| . | | . .
GYDYKCDIWSLGVILYEMLFGKPPF-------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ

LLGHPWL
.| |||.
ILNHPWF
Kinase LmjF25.1990.AA ASK 292-377 40 4.1e-18 56.68 In-house 173-254 (254) Show / Hide 
Range on Protein: 292-377
Range on HMM: 173-254/254
Sequence Identity: 40% (35 aa)

GYTTSADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLPADVHVSAELHSFLDLCFVYDKDLRATAAELLGHPWL
||  .|||||.| |. || ||  ||  .| .| | .|..      |. .| .  .||| . |.  ||  | . ||.|..||  |.|
GYGKPADIWSFGCTMVEMATGKPPF-HELGEPQAAMFKVGMYKKHPE-IPEE--LSAECKNFILRCFEPDPCKRASAQDLLQDPFL
Kinase LmjF25.1990.AA MEKK15 292-377 40 5.3e-17 58.19 In-house 183-264 (264) Show / Hide 
Range on Protein: 292-377
Range on HMM: 183-264/264
Sequence Identity: 40% (35 aa)

GYTTSADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLPADVHVSAELHSFLDLCFVYDKDLRATAAELLGHPWL
||   .||||.| ||.|| |. ||  ||. .. | .| |       ||||  |. | .   |  .|   |.. |.|| .|| ||..
GYGRKSDIWSIGCTVFEMATR-KPPWADM-DRMAAMFYIGAHRDPMPQLP--VKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase LmjF25.1990.AA Dicty2 292-377 43 2.7e-16 53.38 In-house 183-264 (264) Show / Hide 
Range on Protein: 292-377
Range on HMM: 183-264/264
Sequence Identity: 43% (38 aa)

G--YTTSADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLPADVHVSAELHSFLDLCFVYDKDLRATAAELLGHPWL
|   .|. ||||.| |. |. ||. |   || || . .||. .    || || |  .|.|.  ||  ||. |  .|.|| .|| |||.
GNHCCTACDIWSLGCTIIELLTGNPPY-WDL-NPMHAMFRMVQ-DDHPP-LPND--ISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase LmjF25.1990.AA MEKK2 292-377 44 1.6e-14 49.05 In-house 182-262 (262) Show / Hide 
Range on Protein: 292-377
Range on HMM: 182-262/262
Sequence Identity: 44% (38 aa)

GYTTSADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLPADVHVSAELHSFLDLCFVYDKDLRATAAELLGHPWL
||   ||.||.| || ||.| .||  |.     | .|.||      ||||   ||| .   || .|||  |  |  |.||| | . 
GYGRKADVWSIGCTVVEMLT-EKPPWAEY-EAMAAIFKIA-TQPTNPQLPQ--HVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase LmjF25.1990.AA Pkinase_Tyr 5-158 25 6.3e-14 47.78 Pfam 1-161 (270) Show / Hide 
Range on Protein: 5-158
Range on HMM: 1-161/270
Sequence Identity: 25% (42 aa)

VKLNRKLGVGGRGVVYEGFDH----ARGHFVAIKELAYMEPSVPDEDDTE--LAAILSELACMREA-QHTNLVEYYGARR-CAIG--IQIIMEYVSGGSL
.....||| |  |.||.|  .      .  ||.| |       .. .. .  ... ..|.. |..  .| |.| .||.         | |.|||. .|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

DYVLTRC----GPLRENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRCKLADFGVAKQV
.  | .     .||       . ... ... ||.  ... |||.   |.|.| .. .| .||| |. .
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES-KNCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase LmjF25.1990.AA TyrKc 5-377 12 2.8e-12 -24.18 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-377
Range on HMM: 1-280/280
Sequence Identity: 12% (56 aa)

VKLNRKLGVGGRGVVYEGFDHARGHFVAIKELAYMEPSVPDEDDTELAAILSELACMREA--QHTNLVEYYGARRCA-------IGIQIIMEYVSGGSLD
..|..||| |  |.||.|        ||.| |              ......|.  |..   .| |.|  ||. .           . |.|||...|.|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLK

YVLTRCGP-LRENVARAYTRDVLEALHYLHKTMHMCHRDVKPANILITPDGRCKLADFGVAKQVEVT------TPTLPVHAERGGQ--------------
  | ...| |       .  .. .   |||. ..  |||    |.|.. ....| .||| .. ..        . .  .  ..||               
DYLRKHRPKLCMKDLLSFCWQIACGMEYLHS-KNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

---------------------SMGKEEEGN-----------FPRHRNGGRQGYLQTAVGTPWYMAPEVINGGVEDDDEDDEGVELGNAFAVTIGGDANSS
                     . |..   .           . . ..|.|    . .   |  |.                                   
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P--MS-----------------------------------

SFSEDWTSSGLAHTAPDASASPPPLYSSSNYYNPLKSIVKKGRLGARSVGYTTSADIWSVGVTVYEMVTGTKPFGADLTNPSAVLFRIANCAASPPQLPA
                                                                                                    
---------------------------------------------------------------------------------------------------F

DVHVSAELHSFLDLCFVYDKDLRATAAELLGHPWL
 |. ..|...    |  .| . | | .|.  |  .
-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF25.1990.AA STE20 197-213 64 0.000262 11.99 In-house 180-196 (288) Show / Hide 
Range on Protein: 197-213
Range on HMM: 180-196/288
Sequence Identity: 64% (11 aa)

QTAVGTPWYMAPEVING
.| |||| .||||||..
NTFVGTPYWMAPEVIQC
Kinase LmjF25.1990.AA MEKK2 196-213 55 0.004669 6.92 In-house 163-180 (262) Show / Hide 
Range on Protein: 196-213
Range on HMM: 163-180/262
Sequence Identity: 55% (10 aa)

LQTAVGTPWYMAPEVING
...  |||..|.||||||
MKSVTGTPYWMSPEVING
Kinase LmjF25.1990.AA MEKK15 189-212 45 0.011166 5.58 In-house 157-180 (264) Show / Hide 
Range on Protein: 189-212
Range on HMM: 157-180/264
Sequence Identity: 45% (11 aa)

NGGRQGYLQTAVGTPWYMAPEVIN
|. .   |.   |||..||||||.
NRTHSDMLKSMRGTPYWMAPEVIM
Kinase LmjF25.1990.AA STE11-Unclassified 201-213 56 0.014229 5.01 In-house 194-209 (308) Show / Hide 
Range on Protein: 201-213
Range on HMM: 194-209/308
Sequence Identity: 56% (9 aa)

GTPW---YMAPEVING
|||    .||||||..
GTPYQPFWMAPEVIKN
Kinase LmjF25.1990.AA Dicty2 198-211 78 0.019287 4.51 In-house 166-179 (264) Show / Hide 
Range on Protein: 198-211
Range on HMM: 166-179/264
Sequence Identity: 78% (11 aa)

TAVGTPWYMAPEVI
| ||||  ||||||
TVVGTPYWMAPEVI
Kinase LmjF25.1990.AA ASK 197-215 57 0.177274 0.46 In-house 153-171 (254) Show / Hide 
Range on Protein: 197-215
Range on HMM: 153-171/254
Sequence Identity: 57% (11 aa)

QTAVGTPWYMAPEVINGGV
.|  ||  |||||||  |.
ETFTGTLQYMAPEVIDQGQ
Kinase LmjF25.1990.AA Pkinase_Tyr 293-316 42 0.349511 4.63 Pfam 191-216 (270) Show / Hide 
Range on Protein: 293-316
Range on HMM: 191-216/270
Sequence Identity: 42% (11 aa)

YTTSADIWSVGVTVYEMVT-GTKP-F
.||  |.|| ||. .|..| | .| .
FTTKSDVWSFGVLMWEIFTYGEQPTY