Gene LmjF36.0860 (L.major)

LmjF36.0860

Species: L.major
Alias: LmjF36.0860, LmajK221
External Links:
Annotation:

Classification

Group: STE
Family: STE7
Subfamily: MEK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF36.0860.AA Protein None 514 None Fasta, JSON
LmjF36.0860.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of LmjF36.0860.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF36.0860.AA STE7-Unclassified 60-317 35 1.1e-83 284.37 In-house 2-301 (301) Show / Hide 
Range on Protein: 60-317
Range on HMM: 2-301/301
Sequence Identity: 35% (110 aa)

TAGGFLGKGSSGSVRRAVHRG------SKKMVAVKEIKVTGQ--THINEIRRELETLHAGDFA-TPYLVSFYGAFAHEGS---VFIAMEAMD-GSLH---
. .. ||.|..|.|. ..|        ..| .| |.|..  .  . ...| |||.|||   ..  ||.|..|||. ||..   ..|.|| || |||.   
ERLKYLGHGMHGTVVKCLHKNGMVIARDGKIMAWKVIPTMDNDNEFMKQILRELKTLHK--CQPHPYIVHYYGAYYHECMDCKIHICMEYMDCGSLDNKI

ELYKPV-----------PPPVLASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRGE---
..|| .           | |||..|.   ..|| |||. .|.||||.||.|.| ||  | .||.||||. .|| |   | ..||...||||||..|.   
DIYKKMYERGPIRGGWIPEPVLGKIAYQVIHGLWYLHEKHHIIHRDIKPGNILVNS-KGQVKICDFGVCGQLENTLDEAKTWVGCQMYMSPERIQGQMPH

--HYSYGADIWSLGLVVAELAVGVCPY-AGLRGGSSEAR-------FWALLQHLNGDGAALELP-PEMDS---------DLADFISACVVKSPDRRPTCT
   ||   |||||||.  |.| |  ||  ..     ..        || ||.      . .. | |. ..         ...|||| |. |.| .||. .
RPSYSVKSDIWSLGLTIWECATGKYPYEYNFQSEQYNQNFQPENMSFWELLS------CIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIH

ELLR-HPFI
.||  ||.|
QLLNEHPWI
Kinase LmjF36.0860.AA STE7 60-317 34 1.6e-80 273.8 In-house 2-288 (288) Show / Hide 
Range on Protein: 60-317
Range on HMM: 2-288/288
Sequence Identity: 34% (100 aa)

TAGGFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQ--THINEIRRELETLHAGDFA-TPYLVSFYGAFAHEGS--VFIAMEAMD-GSLHELY-------
  .| ||.|..|.|. ..|. | |  |||.|..| .  .  . | .||..||   ..  || | ||||| .||.  ..|.|| || |.|. .|       
EHIGELGHGNYGVVYKMRHKPSGKIMAVKRIRLTNNDPEEQKQILMELDVLHK--CNDCPYIVQFYGAFYTEGDDCIWICMEYMDGGCLDKFYKRVKKVY

-----KPVPPPVLASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRG--EHYSYGADIWS
     ...| ..|. |.   .|||.|||.... |||| ||||.| ||  |..|..|||.. .|. ..  | .|||...||.|||. |  .||.  .|.||
RGIKKGRIPEQILGKIAVAVIKGLHYLHEKHKIIHRDVKPSNILVNS-RGQVKLCDFGICGQLVDSMDAATTFVGCQPYMAPERIDGNKQHYDVRSDVWS

LGLVV-AELAVGVCPYAGLRG-------GSSEAR----FWALLQH-LNG-DGAALELPPEMDSDLADFISACVVKSPDRRPTCTELLR-HPFI
||.    |.|.|  ||.. .         .  .     .. .|.  .|. .   |.   .   .. ||.. |  | |. ||. ..|.  ||||
LGITMGIEMATGRYPYPNWNTHPPDQKQYNNMFQPEMAIFEQLTCIVNENPPPRLP---KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI
S_TKc LmjF36.0860.AA S_TKc 59-317 26 2.2e-72 247.67 SMART 1-231 (231) Show / Hide 
Range on Protein: 59-317
Range on HMM: 1-231/231
Sequence Identity: 26% (75 aa)

ETAGGFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHINEIRRELETLHAGDFATPYLVSFYGAFAHEGSVFIAMEAMDG---SLHELYKP-------
 . .  .|||. |.|....|..... ||.|.||       . ||||.. |.      |..| .|..| . ..... || .||   .|... |        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VPPPVLASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRGEHYSY-GADIWSLGLVVA
   |. . ..... ....| |.|.  . |||||||.|.| ..    |||.|||..  |       ..|.||  ||.|| |   .|..  .|.||.| ...
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE---HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELAVGVCPYAGLRGGSSEARFWALLQHLNGDGAALELPPEMDSDLADFISACVVKSPDRRPTCTELLR-------HPFI
|...|  |.             ......             .... |||. | .| |..|||. |.|.       ||..
EMLCGYPPFP---------QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase LmjF36.0860.AA Pkinase 59-317 25 8.3e-66 229.73 Pfam 1-293 (293) Show / Hide 
Range on Protein: 59-317
Range on HMM: 1-293/293
Sequence Identity: 25% (77 aa)

ETAGGFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHINEIR----RELETLHAGDFATPYLVSFYGAFAHEGSVFIAMEAMDG-----SLH-----E
 . |. .|.||.|.|....|.|. |.||||.||. .. .  ...    .|.. ..  .   |. | .|..|  .... . || ..|     .|.     .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN--HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

LYKPV--PPPVLASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDI----KISDFGVSSNL-ECTKADAHSFVGTVTYMSPERLR-GEHYSYGAD
 ....  .. .. .. . .|.|| |.|. .  |||||||.|.|.. ..|.|    ||.|||..  . .  .  ...|.||  ||.|| .| |..|.. .|
RHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWSLGLVVAELAVGVCPYAGL----RGGSSEARFWALLQ-HLNGDGAAL---------------ELPPEMDSDLADFISACVVKSPDRRPTCTELLRHPF
.||.|....|.. |  |. |     .  .  ...   ..  |  |   .               .. ....... |||. |  | | .|||....| ||.
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

I
.
F
Kinase LmjF36.0860.AA STE 60-317 24 1.6e-65 223.96 In-house 1-359 (359) Show / Hide 
Range on Protein: 60-317
Range on HMM: 1-359/359
Sequence Identity: 24% (90 aa)

TAG-GFLGKGSSGSVRRAVHRG---------------SKKMVAVKEIKVTGQ-----------------THINEIRRELETLHAGD-FATPYLVSFYGAF
  | ...|||..|.| .|...                .....|.|....  .                 . ...| .|.....  .    |. | .||..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

AHEG-------SVFIAMEAMD-GSLHELYK-----------------PVPPPVLASITRLMLKG-LTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFG
 .||       ...|.|| || ||| ...|                 ..| ...| |.|  ||| | |||. .  ||||.||.|.|       .|..|||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL------VKLCDFG

VSSNLECTKA----------------DAHSFVGTVTYMSPERLRG------EHYSYGADIWSLGLVVAELAVGVCPYAGLRGGSSEARF---------WA
|...|. . |                   .||||  .|.||....       .|.. .||||||... |.| |  |.. .   .   ..         . 
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFE

LLQHLNGDGAALEL-----------------PPEMDSDLADFISACVVKSPDRRPTCTELLR--HPFI
.|. .||.   |.                  | .. ... |||. | .| |. ||| ..||.  ||||
QLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF36.0860.AA MEK1 60-253 45 3.1e-53 180.09 In-house 2-195 (297) Show / Hide 
Range on Protein: 60-253
Range on HMM: 2-195/297
Sequence Identity: 45% (91 aa)

TAGGFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHI-NEIRRELETLHAGDFATPYLVSFYGAFAHEGSVFIAMEAMDG-SLHELYKPV---PPPVL
   | ||.|  | | ...|| .  ..| | |..  .  | | | |||. ||   .  ||.| |||||  .| . | || ||| ||  . | .   |  .|
EKIGELGHGNGGVVMKCRHRHTGMIMARKLIHLEIKPAIRNQIIRELQVLHECNS--PYIVGFYGAFYSDGEISICMEYMDGGSLDQVLKKAGRIPEKIL

ASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRGEHYSYGADIWSLGLVVAELAVGVCP
  ..  .|.|||||.   ...||| ||||.| ||| |.||. |||||  |    . | |||||  |||||||.| ||.  .||||.|| . |.|.|  |
GKVSVAVLRGLTYLRDKHKIMHRDVKPSNILVNSR-GEIKLCDFGVSGQL--IDSMANSFVGTRSYMSPERLQGTHYTVQSDIWSMGLSLVEMAIGRYP
Kinase LmjF36.0860.AA MEK5 60-317 36 7.8e-53 181.84 In-house 2-254 (254) Show / Hide 
Range on Protein: 60-317
Range on HMM: 2-254/254
Sequence Identity: 36% (94 aa)

TAGGFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHIN-EIRRELETLHAGDFATPYLVSFYGAFAHEGSVFIAMEAMDGSLHELYKPVPPPVLASIT
     ||.|  |.| .| |  | |..||| | .     .  .|  ||| |.  |   ||.. |||||  |  . |  | |||   ..|. .|  .|  .|
RYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCD--SPYIIGFYGAFFVENRISICTEFMDGGSLDMYRCIPEHILGRMT

RLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRGEHYSYGADIWSLGLVVAELAVGVCPYAGLR
  . |||.||   . ..||| ||||.| | . |.||. |||||. |    . .. ..||  || |||. |..|   .|.||||. . |.|.|  ||  ..
VAIVKGLNYLWNLK-IMHRDVKPSNMLVNTQ-GQIKLCDFGVSTQL--VNSITRTYIGTNAYMAPERISGDQYGIHSDVWSLGIFFMEMATGRFPYPQIQ

GGSSEARFWALLQHLNGDGAALELPPEMDSDLADFISACVVKSPDRRPTCTELLRHPFI
    |    .||| .  . .      .      .||  |. | |  ||   .|. ||||
RDQGELMPIQLLQCIVDEHPPRLPVDKFSEPFVHFINQCMQKQPKDRPKPQDLMQHPFI
Kinase LmjF36.0860.AA TKL 65-315 18 8e-45 155.23 In-house 1-364 (364) Show / Hide 
Range on Protein: 65-315
Range on HMM: 1-364/364
Sequence Identity: 18% (69 aa)

LGKGSSGSVRRAVHRGSK--------KMVAVKEIKVTG-------------------------QTHINEIRRELETLHAGDFATPYLVSFYGAFAHEGS-
.|.|..| | ....||          | |||| .|..                           .. .. ..| |...   .  | .|.|.|.   ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------VFIAMEAM-DGSLHELYKPVPPPVLASITRLMLKGLTYLHRTRH-------LIHRDLKPSNVLYNSR-------------TGDIKISD
             .| || .  |||....    .... .. . . .|. |||  .        .||||||..|.| ..              ....||.|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD

FGVSSNLECTKA-------------------DAHSFVGTVTYMSPERLRGE----------------HYSYGADIWSLGLVVAELAVGVCPYAGLRGGSS
|| | ... ..                      .. .||  .|.|| |||.                 ||  .|..| |.|  |.. .  ||...   . 
FGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPM

EARFWALLQ---HLNGD-GAALELP------------PEMDSDLADFISACVVKSPDRRPTCTELLRHP
...    ..    ...| |  ...|            | .. .... .  |    |. ||...|.| . 
IFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LmjF36.0860.AA MEK4 63-317 31 2.6e-44 142.45 In-house 5-275 (275) Show / Hide 
Range on Protein: 63-317
Range on HMM: 5-275/275
Sequence Identity: 31% (87 aa)

GFLGKGSSGSVRRAVHRGSKKMVAVKEIK--VTG-----QTHINEIRRELETLHAGDFATPYLVSFYGAFAHEGSVFIAMEAMDGSLHELYKPV------
| .|.|. |.|.  .|. | |..||| |.    .     .      ..|...  .     || | ||||   ||   | || || |.  .|| |      
GEIGNGAFGTVNKMWHKESGKIMAVKRIRCNNVDPDDAFHKEQKRLLMEHDVVMKSE-NCPYIVKFYGACFKEGDCWICMELMDISMDKFYKYVYMVQKS

--PPPVLASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRG----EHYSYGADIWSLGLV
  |  ... ||    . | || .| . |||| ||||.| . |.|..|  |||..  |.   |  |  .| . || |||.      . |    |.||||  
RIPENIMGHITVCTVDALNYLKETHKIIHRDVKPSNILLD-RHGCVKLCDFGICGQLVDSIAKTHD-AGCRPYMAPERIDPEQNMDGYDIRSDVWSLGIT

VAELAVGVCPYAGLRGGSSEARFWALLQHLNGDGAALELPPE---MDSDLADFISACVVKSPDRRPTCTELLRHPFI
  |.| |. || .    |    |  . .  .||   |.   .      .. .||  |  |  . ||   .|. .||.
MYEVATGKFPYRKWNDASV---FDQICMVVKGDPPILHHDHHDMHYSMPMCRFINTCLTKDRNHRPKYDNLKKFPFY
Kinase LmjF36.0860.AA SLK 63-317 29 8.2e-43 142.19 In-house 5-259 (259) Show / Hide 
Range on Protein: 63-317
Range on HMM: 5-259/259
Sequence Identity: 29% (77 aa)

GFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHINEIRRELETLHAGDFATPYLVSFYGAFAHEGSVFIAME-----AMDGSLHELYKPVPPPVLASI
| || |  | | .|.|.  |.. | | |..  . ....   |.. |   .   |..|  |.|. ... ... .|     |.|  . || .|.  . .. .
GELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK--HPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQIQYV

TRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSP-----ERLRGEHYSYGADIWSLGLVVAELAVGVC
 . |. .|..||. . .||||||  |.|     ||... |||||  .. |     .|.||  .| |     | .. . | | |||||||. . |.| .  
CKHMCEALNWLHSNK-VIHRDLKAGNILM-TMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEP

PYAGLRGGSSEARFWALLQHLNGDGAALELPPEMDSDLADFISACVVKSPDRRPTCTELLRHPFI
|.  .           ||.    .   || | .  ..  ||.  |.|| |. |.|  .|..|...
PHHEM------NPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase LmjF36.0860.AA STE20 65-255 30 3.7e-41 143.07 In-house 7-228 (288) Show / Hide 
Range on Protein: 65-255
Range on HMM: 7-228/288
Sequence Identity: 30% (69 aa)

LGKGSSGSVRRAVHRGSKKM----VAVKEIKVTGQ----THINEIRRELETLHAGDFATPYLVSFYGAFAHE----GSVFIAMEAMDG-SLHELYK----
.|.||.|.| .| |. ...     ||.| ...  .     ....|  |   .   ..  |. |..||..  .     . .|.|| ..| ||....|    
IGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMK--QCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMKHCMK

--------PVPPPVLASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLEC----TKA-DAHSFVGTVTYMSPERLRG-----E
        |   .  | |.| .|.|| |||. .| ||||.|  |.| ... |..|..||||.. |.     |..    .||||  .|.|| ...      
CGKNHKGHPMNEEQIAYICREVLQGLDYLHS-NHIIHRDIKADNILLTED-GEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDK

HYSYGADIWSLGLVVAELAVGVCPYA
 | | .||||||    |.| |  ||.
GYDYKCDIWSLGITAIEMAEGEPPYF
Kinase LmjF36.0860.AA MST 155-258 42 5.2e-26 79.59 In-house 100-201 (254) Show / Hide 
Range on Protein: 155-258
Range on HMM: 100-201/254
Sequence Identity: 42% (44 aa)

ASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECTKADAHSFVGTVTYMSPERLRGEHYSYGADIWSLGLVVAELAVGVCPY
|.| .  |.|| |||. .  ||||.|. | | | . |  | .|||||. |  | | . ...||  .|.|| .    | . |||||||    |.| |  ||
ACILYDTLQGLQYLHDNKK-IHRDIKAGNILLNHE-GECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPPY

AGLR
. ..
SDIH
TyrKc LmjF36.0860.AA TyrKc 59-317 22 3.8e-14 6.0 SMART 1-280 (280) Show / Hide 
Range on Protein: 59-317
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

ETAGGFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHINEIRRELETLHAGDF--ATPYLVSFYGAFAHE-------GSVFIAMEAMD-GSLHEL---
 | |  || |  | |.... .    .|||| .|      . ...||.. ..   .    | .| .||.  ..       . ..| || |. |.|..    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---REDFMREARIMCK--LGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YKP-VPPPVLASITRLMLKGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNLECT-------KADA-----HS-FVGTVTYMSPERLRGEHY
..| .... | |.     .|  |||. ...|||||   |.|....   .|||||| | ...         .        .. ..  .  |.|| ..   .
HRPKLCMKDLLSFCWQIACGMEYLHS-KNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SYGADIWSLGLVVAELA-VGVCPYAG-----LRGGSSEARFWALLQHLNGDGAALELPPE--------MDSDLADFISACVVKSPDRRPTCTELLRHPFI
.   |.|| | .  |.   |  || |     .    | ..  .....    |  .. ||.        . ... . .. |    |. ||| .|.  | ..
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMM----SNQEVIEYVKQ----GYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF36.0860.AA MST 288-317 43 4.6e-13 37.78 In-house 225-254 (254) Show / Hide 
Range on Protein: 288-317
Range on HMM: 225-254/254
Sequence Identity: 43% (13 aa)

SDLADFISACVVKSPDRRPTCTELLRHPFI
... ||.. | .|.|. |.| ..|| ||||
QEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase LmjF36.0860.AA STE20 292-317 53 7.7e-10 32.44 In-house 263-288 (288) Show / Hide 
Range on Protein: 292-317
Range on HMM: 263-288/288
Sequence Identity: 53% (14 aa)

DFISACVVKSPDRRPTCTELLRHPFI
||.. | .| |. ||| ..||.||||
DFVDKCLQKDPEKRPTASQLLKHPFI
Kinase LmjF36.0860.AA MST 63-136 31 1e-06 17.04 In-house 5-76 (254) Show / Hide 
Range on Protein: 63-136
Range on HMM: 5-76/254
Sequence Identity: 31% (24 aa)

GFLGKGSSGSVRRAVHRGSKKMVAVKEIKVTGQTHINEIRRELETLHAGDFATPYLVSFYGAFA--HEGSVFIAME
. || || ||| .|.|. ..| ||.| ..|   . ..||  |  ..   .   .| | .|| .    .  . | ||
EKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIMQ--QCKSKYIVKYYGSYFDAKNNHCWIVME
Kinase LmjF36.0860.AA MEK1 288-317 36 1.2e-05 14.69 In-house 268-297 (297) Show / Hide 
Range on Protein: 288-317
Range on HMM: 268-297/297
Sequence Identity: 36% (11 aa)

SDLADFISACVVKSPDRRPTCTELLRHPFI
... ||.. |. | || | .  .|. |.||
EEFQDFVDKCLIKNPDERADLKQLMVHTFI
Kinase LmjF36.0860.AA Pkinase_Tyr 65-140 24 0.000645 13.89 Pfam 7-91 (270) Show / Hide 
Range on Protein: 65-140
Range on HMM: 7-91/270
Sequence Identity: 24% (21 aa)

LGKGSSGSVRRAVHR----GSKKMVAVKEIKVTGQTH---INEIRRELETLHAG-DFATPYLVSFYGAFA-HEGS--VFIAMEAMDG
||.|. |.|.... .    . |  |||| .| .   .   . .  ||.....   .   | .|..||.   ....  ..| || | .
LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHH--PNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase LmjF36.0860.AA Pkinase_Tyr 163-317 24 0.001213 12.96 Pfam 122-270 (270) Show / Hide 
Range on Protein: 163-317
Range on HMM: 122-270/270
Sequence Identity: 24% (39 aa)

KGLTYLHRTRHLIHRDLKPSNVLYNSRTGDIKISDFGVSSNL-----ECTKADAHSFVGTVTYMSPERLRGEHYSYGADIWSLGLVVAELAV-GVCP-YA
||. ||.. ...|||||   |.| .. .. .||.||| .  .       ...  ..    .  |.|| ..   ..   |.|| | .  |.   |  | |.
KGMEYLES-KNCIHRDLAARNCLVTE-NNVVKICDFGLARDIYNDDYY-YRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYP

GLRGGSSEARFWALLQHLNGDGAALELPPEMDSDLADFISACVVKSPDRRPTCTELLRHPFI
|.   .       .....  ||  .. |.    .. | .  |  . |..||| .|.  | ..
GM-SNEE------VYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEI--HEQL