81037.m00072

Species: T.vaginalis
Alias: 81037.m00072, TvagK0264
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81037.m00072.AA Protein None 1103 None Fasta, JSON
81037.m00072.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of 81037.m00072.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81037.m00072.AA TKL 23-277 21 2.5e-68 233.32 In-house 1-364 (364) Show / Hide
Range on Protein: 23-277
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

LGKGSYAHVFAARSKTTK--------EIFALKKFHSNF-------------------------TSKKNRMMFEREVSVMAKLIHSCVLGLRGYFLPPPE-
.|.|... |. .. . .         .  | |||.|.                          .....|  .|.|. .| .| |  .. . || . ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

--------SDLCPLILMDYMKNGDLFTILVKESKNKVQLGWDNTKRMMNVFGIAYGMAHIHACG--------GIHRDLKPANIMLNENFE----------
        ..  . | |.|...|.|. .|               .|.  . .|| ||.. |...         ||||||..||...||..          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----PKIADFGLAK-IEEDNN-------------------LQSMIGGSPFWMAPELFLGE----------------QYTNKVDVYAYGVLLYQLLTDLIP
    .||.||||.. .....|                     ....|.| |||||.. |.                .|. |.|||..|..|. .||  .|
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP

FD--GKITTIAL-------GKKITSGERPPIP------------ETLPTFYSEIITACWAQEPESRPTFEQIYRHI
..  . .. |.         . .  |.|||||            .. |. ...... ||...||.||.|..|  ..
YYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Pkinase 81037.m00072.AA Pkinase 17-277 26 7.3e-64 223.27 Pfam 1-293 (293) Show / Hide
Range on Protein: 17-277
Range on HMM: 1-293/293
Sequence Identity: 26% (82 aa)

FEIGKLLGKGSYAHVFAARSKTTKEIFALKKFHSNFTSKKNRMMFER--EVSVMAKLIHSCVLGLRGYFLPPPESDLCPLILMDYMKNG----DLFTILV
..||. .|.||.. |. .. | | .|.|.|..    .... ..   |  |...|..| | ... |...|    .....  . |.|. .|    |||... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIY--MVMEYCEGGLYVMDLFDYIS

KESKNKVQL--GWDNTKRMMNVFGIAYGMAHIHACGGIHRDLKPANIMLNENFEP----KIADFGLAKI--EEDNNLQSMIGGSPFWMAPELFL-GEQYT
   ...  .   ..  |..|    |. |....|..| |||||||.||....| ..    ||.||||||   .  |   . . |.|..||||. . |. |.
T--WRHGCFYFSEWECKFYM--YQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYG

NKVDVYAYGVLLYQLLTDLIPFDGK---ITTIALGKKITSGERPPIPETLPTFYS-----------------------EIITACWAQEPESRPTFEQIYR
 |||....|..||..|.   ||.|.   .. .   ..|    .||...  |. .|                       ..|. |... |..|||.|||  
PKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

H--I
|  .
HPWF

S_TKc 81037.m00072.AA S_TKc 17-279 26 7.3e-60 206.1 SMART 1-231 (231) Show / Hide
Range on Protein: 17-279
Range on HMM: 1-231/231
Sequence Identity: 26% (73 aa)

FEIGKLLGKGSYAHVFAARSKTTKEIFALKKFHSNFTSKKNRMMFEREVSVMAKLIHSCVLGLRGYFLPPPESDLCPLILMDYMKN--GDLFTILVKESK
.||....|||... |. .| | |..|.|.|. .          ...||.... |  |  .  | ..|        .  . |.|. .  ||||....|  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGR

NKVQLGWDNTKRMMNVFGIAYGMAHIHACGGIHRDLKPANIMLNENFEPKIADFGLAKIEEDNNLQSMIGGSPFWMAPELFLGEQYTN-KVDVYAYGVLL
.. . . .       .  |. .....|  | |||||||.||.|.|  . ||.|||||..       . . |.|..||||..   .|.  |.|... |..|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

YQLLTDLIPFDGKITTIALGKKITSGERPPIPETLPTFYSEIITACWAQEPESRPTFEQIYR-------HILE
| .|.   ||.   .  .. |||            | . . .|  |.  .|| |||  .. .       |   
YEMLCGYPPFP---QMQMMFKKIG----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 81037.m00072.AA Dicty4 17-280 29 4.7e-57 188.9 In-house 1-277 (277) Show / Hide
Range on Protein: 17-280
Range on HMM: 1-277/277
Sequence Identity: 29% (85 aa)

FEIGKLLGKGSYAHVFAARSKTTKEIFALKKF-HSNFTSKKNRMM-FEREVSVMAKLIHSCVLGLRGYFL----PPPESDLCPLILMDYMKNGDLFTILV
  |....||||.. |. .. . .  . | ||.   | ..  |..  | .||. |.|. |  .. . |. .     |..    ..| . ||  |.|...| 
INIEQRIGKGSFGEVYKGTWRGK--EVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGK----MCIVTEYMPKGNLYSLLH

K---ESKNKVQLGWDNTKR---MMNVFGIAYGMAHIHA--CGGIHRDLKPANIMLNENFEPKIADFGLAK----IEEDNN-LQSMIGGSPFWMAPELFLG
.   | . ...| |   ||   |.  | .| ||.. |.  .  ||||||..|..  .|.  |..||||..    .|. .  . ... |.| |||||   .
DKPSEQQQSIKLDWPLIKRAMRMA--FDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC-GTPCWMAPEVMMH

EQYTNKVDVYAYGVLLYQLLTDLIPFD-GKITTIALGKKITS-GERPPIPETLPTFYSEIITACWAQEPESRPTFEQIYRH-ILEA
. |. |.||| .| .|...||  .|.    . .  ..  . . ..|||||   |..... |. ||  .|..||.||.|    |||.
QPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH

Kinase 81037.m00072.AA TKL-Unique 19-277 28 7.4e-53 181.92 In-house 1-290 (290) Show / Hide
Range on Protein: 19-277
Range on HMM: 1-290/290
Sequence Identity: 28% (85 aa)

IGKLLGKGSYAHVFAARSKTTKEIFALKKFH-SNFTSKKNRMMFEREVSVMAKLI-HSCVLGLRGYFL--PPPESDLCPLILMDYMKNGDLFTILV----
.....| |.|. |.  . |  ... |.|.||  .  |.. .  ||.||..| ||  |  .. . ||     ......|  | |.|.  | |   |     
FWNKIGEGGYGQVY--KGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMC--IVMEYCPGGSLYDVLHQNNN

KESKNKVQLGWDNTKRMMNVFGIAYGMAHIHACGG--IHRDLKPANIMLNEN-----FEPKIADFGLAKIEEDNNLQSMIG----------GSPFWMAPE
    |.  .  .. .|. ..  || || ..| |..  ||||||. |. ...|     .  ||.||||.|.   .|  . ..          ||..|||||
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

LFLG--EQYTNKVDVYAYGVLLYQLLTDLI------PFDGKITTIALGKKITS---GERPPIPETLPTFYSEIITACWAQEPESRPTFEQIYRHI
.. .  .||..|.|||..|. |. ..|  |      |..| .. ... .....   . |||||. .|  |...|..||...|. ||.|..|.  .
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQG-MDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL

Kinase 81037.m00072.AA Dicty4-Unclassified 17-277 32 9.2e-51 172.07 In-house 1-263 (263) Show / Hide
Range on Protein: 17-277
Range on HMM: 1-263/263
Sequence Identity: 32% (86 aa)

FEIGKLLGKGSYAHVFAARSKTTKEIFALKKFHSNFTSKKNRMM--FEREVSVMAKLIHSCVLGLRGYFLPP--PESDLCPLILMDYMKNGDLFTILV-K
  | . .|||  . |     |  |.. | ||| .|  .    |.  | .|| ..  . |   . ..|| . |    | .|  | |  |  | || .   |
IQIDQFIGKGHFSKVHKGNWK-GKDV-AVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMC--IVMEFMHKGNLFEVIHSK

ESKNKVQLGWDNTKRMMNVFGIAYGMAHIHACGGIHRDLKPANIMLNENFEPKIADFGLAKIEEDNNLQSMIGGSPFWMAPELFLGEQYTNKVDVYAYGV
 |  .  .  | |  .   | || ||.| |    ||||.| .||..  .|  ||||||..   . |     |.| | | .||   .| |. | ||| |..
PSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAM

LLYQLLTDLIPFDGKITTIALGKKITS-GERPPIPETLPTFYSEIITACWAQEPESRPTFEQIYRHI
.|| |.|   |. .    . ..  . . . || ||.  . |..  |  ||  .|  |||..||    
MLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL

Kinase 81037.m00072.AA Dicty5 132-281 38 1.2e-45 155.11 In-house 112-260 (260) Show / Hide
Range on Protein: 132-281
Range on HMM: 112-260/260
Sequence Identity: 38% (58 aa)

GIAYGMAHIHACGGIHRDLKPANIMLNENFEPKIADFGLAK-IEEDNNLQSMI-GGSPFWMAPELFLGEQYTNKVDVYAYGVLLYQLLTDLIPFDGKITT
.|| .| |.|  . ||||||  |. ..||.. || |||    .  || ..  .  | . |||.||| |  |..|.|||..|. |. ..|   |.|  |. 
DIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFV--DNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYD-NINN

IALGKKITSGERPPIPETLPTFYSEIITACWAQEPESRPTFEQIYRHILEAT
.     . .|||| || . || .| .| .|| | |  ||.|  |   .    
WNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII

Kinase 81037.m00072.AA LRRK 17-279 23 1.5e-45 157.6 In-house 1-351 (351) Show / Hide
Range on Protein: 17-279
Range on HMM: 1-351/351
Sequence Identity: 23% (84 aa)

FEIGKLLGKGSYA-HVFAARSK--------------------------TTKEIFALKKFHSN---------------------------------FTSKK
..|....|.|...  |. |. .                             .  | ||..                                   .....
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

NRMMFEREVSVMAKLIHSCVLGLRGYFLPPPESDLCPLILMDYMKNGDLFTILVKESKNKV-----QLGWDNTKRMMNVFGIAYGMAHIHACG--GIHRD
 |  | .||..| .| |.... | |. . |      . . |.|. .||| . | ......       ..|  . . .    || ||.. | .    ||||
FR-EFRHEVWIMSHLNHPNIVSLKGFCIHP------LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIA--LQIAKGMEYLHSHNPPIIHRD

LKPANIMLNENFEP------------KIADFGLAK--IEEDNNLQSMIGGSPFWMAPELFLGE---QYTNKVDVYAYGVLLYQLLTDL-IPFDGKIT---
||. || |..  ..            ||||||.        . . .  .| | |||||   ..   .|| |||.|..|..|. ||| . .|||. ..   
LKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDE-HDFFD

----TIALGKKITSGERPPIPET-LPT-----FYSEIITACWAQEPESRPTFEQIYRHILE
    .. . .||..| ||.||..  |       |.. |. ||...|..||.|.||   . .
HMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ

Kinase 81037.m00072.AA MLK 17-277 27 6e-44 150.34 In-house 1-291 (291) Show / Hide
Range on Protein: 17-277
Range on HMM: 1-291/291
Sequence Identity: 27% (81 aa)

FEIGKLLGKGSYAHVFAARSKTTK---EIFALKKFHSNF-------TSKKNRMMFEREVSVMAKLI-HSCVLGLRGYFLPPPESDLCPLILMDYMKNGDL
... . .|.||.  |. .| . .     | |.|......       .....  |. |..... ..  |.|.  ..|  | || ...|  |.| |. .| |
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFC--IVMEYCEGGSL

FTILVKES--------KNKVQLGWDNTKRMMNVFGIAYGMAHIHACGG---IHRDLKPANIMLNE------NFEPKIADFGLAK-IEED-NNLQSMIGGS
...|  ..        ..|     |    |   . .| ||.  |.      ||||||. ||.. |      .   ||.|||... . .   |  |.. |.
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNA-GT

PFWMAPELF---LGEQYTNKVDVYAYGVLLYQLLTDLIPFDGKITTIALGKKITSGE-RPPIPETLPTFYSEIITACWAQEPESRPTFEQIYRHI
. ||||| .    .|.|. |.||. .||.|...||  .|... .  .| . ...  . ||||| | |   .. .. || |.|..||.| ||  | 
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL

Kinase 81037.m00072.AA TK 17-277 16 1e-40 133.73 In-house 1-486 (486) Show / Hide
Range on Protein: 17-277
Range on HMM: 1-486/486
Sequence Identity: 16% (78 aa)

FEIGKLLGKGSYA---HVFAA----------------------------RSKTTKEIFALKKFHSNFTSKKNRMMFE---------REVSVMAKLI----
 ..|| ||.| .     |. .                              ||.  .  ||. ...    .  ...          .|...|...     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HSCVLGLRGYFLPPPES--------DLCPLILMDYMKNGD----LFTILV--KESKNKVQLGWDN----------------------------------
 |  .. | |. . . ..        .  ..|.| ||..||    | . |   .. ... | . ||                                  
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------TKRMMNVFG--IAYGMAHIHAC------GGIHRDLKPANIMLNENFE-----------PKIADFG---
                                | . .  .   || ||...|..      . .||||   |....||              ||||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LAKIEEDNNLQSMIG------------------------GSPF---WMAPELFLGEQ---------YTNKVDVYAYGVLLYQLLTDL-IPFDGKI
     ||.  ...      .                        |  .   ||||| ... .         .| | ||...|||.. ..|    |. | .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TT---------IALGKKITSG--------------ERPPIPETLP--------------TFYSEIITACWAQEPESRPTFEQIYRHI
.            . .....|               |.| |.  |              ..| .... ||. .|| ||||.|... .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase 81037.m00072.AA RIPK 23-277 26 1.2e-40 136.27 In-house 1-290 (290) Show / Hide
Range on Protein: 23-277
Range on HMM: 1-290/290
Sequence Identity: 26% (76 aa)

LGKGSYAHVFAARSKTTKEIFALKKFHSNF--TS--KKNRMMFEREVSVMAKLIHSCVLGLRGYFLPPPESDLCPL--ILMDYMKNGDLFTILVKESK-N
.|.|.   || || .. ..  | |   .    |   .. ||   .|.  |.||... .. . |    .     | |  | | ||.|| |   |  ...  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

KVQLGWDNTKRMMNVFGIAYGMAHIHACG--GIHRDLKPANIMLNENFEPKIADFGLAKIEEDNNLQS--------MI------GGSPFWMAPELFL--G
.  . |. . ||  .  |. ||   |  .   |||||||.|| .  ||  ||||||||.  .   ...         .      .|    |.||.|.   
HHPDPWPLRCRM--IHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

EQY----TNKVDVYAYGVLLYQLLTDLIPFDGKITTIALGKKITSGERPPIPETLPTFYS--------EIITACWAQEPESRPTFEQIYRHI
       | | ||| ........||   |. .....  .  .. .| ||....  . . .        | .. ||.|.|..||.|  .   .
KKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT

Kinase 81037.m00072.AA DRK 61-280 33 1.1e-39 132.06 In-house 44-258 (258) Show / Hide
Range on Protein: 61-280
Range on HMM: 44-258/258
Sequence Identity: 33% (77 aa)

FEREVSVMAKLIHSCVLGLRGYFLPPPESDLCPLILMDYMKNGDLFTILVKESKNKVQLGWDNTKRMMNVFGIAYGMAHIHACGGI--HRDLKPANIMLN
| ||. .| .| |  .    |  . ||.    ..| | ||  | |  ||  ||   ... |   |.||  | .| ||   | |  |  |||||  |    
FHREINLMCQLRHPNICQFMGTCNNPPD----ICICMEYMPRGSLYNILHDES---IEMDWPLMKQMM--FDCAKGMIYLHCCNPIIIHRDLKSHNLLVD

ENFEPKIADFGLAK----IEEDNNLQSMIGGSPFWMAPELFLGEQYTNKVDVYAYGVLLYQLLTDLIPFDGKIT---TIALGKKITSGERPPIPETLPTF
|..  |.|||||.     ...      |. | | | |||    . || | ||| ... |  ..| ..|. |. |    .. |.    |.|||.|.  |  
EHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRH---GMRPPMPQWCPPK

YSEIITACWAQEPESRPTFEQIYRHILEA
|   .. ||  .|  ||.....   .|||
YIQLMNDCWNEDPQHRPSMQECLE-RLEA

Kinase 81037.m00072.AA Pkinase_Tyr 17-277 29 1.7e-37 127.63 Pfam 1-270 (270) Show / Hide
Range on Protein: 17-277
Range on HMM: 1-270/270
Sequence Identity: 29% (83 aa)

FEIGKLLGKGSYAHVFAARSK----TTKEIFALKKFHSNFTSKKN--RMMFEREVSVMAKL-IHSCVLGLRGYFL-P-PPESDLCPLILMDYMKNGDLFT
 ..|| ||.|.. .|. .. |     ||   | |.   . .....  | .| ||...| .|  |  .. | |  .    |     ..| | ||..||| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLD

ILVKE--SKNKVQLGWDNTKRMMNVFGIAYGMAHIHACGGIHRDLKPANIMLNENFEPKIADFGLAKIEEDNNLQ-SMIG---GSPFWMAPELFLGEQYT
 | |   .|... . .     |   . || ||.. .. . |||||   |....||.  ||.|||||.  ..      . |      .||||| .    .|
YLRKHREDKQPLTMKD--LLQMC--WQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFT

NKVDVYAYGVLLYQLLT--DLIP-FDGKITTIALGKKI-TSGERPPIPETLPTFYSEIITACWAQEPESRPTFEQIYRHI
 | ||...|||.. ..|  . .| . |  .   . ..|  .|.| |.||  |    .... ||...|| ||||..|....
TKSDVWSFGVLMWEIFTYGE-QPTYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL

Kinase 81037.m00072.AA TyrKc 17-277 26 6.1e-36 126.63 SMART 1-280 (280) Show / Hide
Range on Protein: 17-277
Range on HMM: 1-280/280
Sequence Identity: 26% (79 aa)

FEIGKLLGKGSYAHVFAARSKTTKEIFALKKFHSNFTSKKNRMMFEREVSVMAKL--IHSCVLGLRGYFLPPPE---SDLCPLILMDYMKNGDLFTILVK
 . || || | .  |. .. |   .  | |. ...      |..| || ..| ||   | ... | |. . . .   ..  ..|.| ||..|||   | |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ESKNKVQLGWDNTKRMMNVFGIAYGMAHIHACGGIHRDLKPANIMLNENFEPKIADFGLAKIEEDN-------NLQSMIG--GSP-----FWMAPELFLG
  ..   | ..    ..  . || ||...|  . |||||   |....||.  ||.||||..  .|           .. .  |.       ||||| .  
HRPK---LCMKDLLSFC--WQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

EQYTNKVDVYAYGVLLYQLLTD-LIPFDG----KITTIALGKKITSGERPPIPET--------LPTFYSEIITACWAQEPESRPTFEQIYRHI
  .| | ||...||... ..|.   |  |    ... . . ... .|.|.|.|.          |.   .|.. ||. .||.||||..|.. .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 81037.m00072.AA DRK 17-32 43 0.087275 1.87 In-house 1-16 (258) Show / Hide
Range on Protein: 17-32
Range on HMM: 1-16/258
Sequence Identity: 43% (7 aa)

FEIGKLLGKGSYAHVF
  ||   |.|.|. ||
IKIGNRIGRGNYGEVF

Sel1 81037.m00072.AA Sel1 451-486 27 1.8e-05 21.31 Pfam 1-43 (43) Show / Hide
Range on Protein: 451-486
Range on HMM: 1-43/43
Sequence Identity: 27% (12 aa)

VECAFILGKYS--YTGEFG---EK-D-LAT-AEKYLEFAANSGN
.  .. || |   |.|.||   .. | ..  | .... ||. |.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 343-378 28 9.7e-05 18.88 Pfam 1-43 (43) Show / Hide
Range on Protein: 343-378
Range on HMM: 1-43/43
Sequence Identity: 28% (13 aa)

IESLYYLGKMII---DGK----I---NNYDKIQGIKFLKKAAEGGH
  . |.|| |.    .|.    .   ..|.| .......|||| ||
P-AQYNLG-MYYMYYHGQFGGCVPQDDDYEK-EAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 379-414 22 0.000395 16.85 Pfam 1-43 (43) Show / Hide
Range on Protein: 379-414
Range on HMM: 1-43/43
Sequence Identity: 22% (10 aa)

AEAQYECG--MALYKGE-D--VGC-N-KIM-AAEFFKQAAKSYL
. |||. |  ...|.|. .  |   . .   |......||.   
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 415-450 22 0.016159 11.5 Pfam 1-43 (43) Show / Hide
Range on Protein: 415-450
Range on HMM: 1-43/43
Sequence Identity: 22% (10 aa)

PGAIIMLS--KMLLVGD--G-VEM-S-KAK-SKKLLQILADKQN
| |  .|    |.. |.  | |.    ..| . ...|  |.. .
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 982-1017 25 7.6e-08 29.19 Pfam 1-43 (43) Show / Hide
Range on Protein: 982-1017
Range on HMM: 1-43/43
Sequence Identity: 25% (11 aa)

TLGMYNYA--VTLQTGN--G-VER-D-ITS-AAKFYKMAADRGD
  ..||..    ...|   | |.. | .   |...|..||..|.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 1055-1091 25 1.6e-07 28.12 Pfam 1-43 (43) Show / Hide
Range on Protein: 1055-1091
Range on HMM: 1-43/43
Sequence Identity: 25% (11 aa)

PRGMFQYG--KMLWYGT--G-VQKRD-QQT-AASYIKEAAARGY
| .....|   |...|   | | ..|  .  |. . . ||..|.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 841-876 25 1.5e-05 21.55 Pfam 1-43 (43) Show / Hide
Range on Protein: 841-876
Range on HMM: 1-43/43
Sequence Identity: 25% (11 aa)

SGAMLECS--NFLSNGM--G-VKK-D-LRK-AAYMCKLSAESGN
. |...     .. .|   | |.. | ..| |.|  ...|| |.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 805-840 28 2.3e-05 20.95 Pfam 1-43 (43) Show / Hide
Range on Protein: 805-840
Range on HMM: 1-43/43
Sequence Identity: 28% (13 aa)

LEAKYQCGNYLV---RGF--G-TKQ-D-LSK-AAIYFYDAAKNGH
  | |. | ..    .|   | ..| | . | |. ..  ||..||
P-AQYNLG-MYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 1018-1054 18 6.8e-05 19.38 Pfam 1-43 (43) Show / Hide
Range on Protein: 1018-1054
Range on HMM: 1-43/43
Sequence Identity: 18% (8 aa)

VDACIHYS--QLLATGW-EG-NQK-D-LQQ-SANYAKKAADLGN
. |.  .   ... .|   |   . | ... .. . .|||..|.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 946-981 20 9.5e-05 18.9 Pfam 1-43 (43) Show / Hide
Range on Protein: 946-981
Range on HMM: 1-43/43
Sequence Identity: 20% (9 aa)

CDGLSSYG--HFLAEGL--G-CNK-D-PVK-AAECFRAAALMGS
  .   .|  ... .|.  | . . | . | |..... || .|.
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 913-945 22 0.000147 18.28 Pfam 1-43 (43) Show / Hide
Range on Protein: 913-945
Range on HMM: 1-43/43
Sequence Identity: 22% (10 aa)

VKAMLAAA--YYMWT------VEK-D-LPK-ALKYYKMAADQQD
. |... .  |. ..      |.. | . | |...|..||.| .
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 770-804 15 0.081913 9.16 Pfam 1-43 (43) Show / Hide
Range on Protein: 770-804
Range on HMM: 1-43/43
Sequence Identity: 15% (7 aa)

INAMYEYALIL---AAE--S-NKY-S-AQQ-SAIYMKKAADKGH
  |.|......     .     .     .. .. ...|||..||
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH

Sel1 81037.m00072.AA Sel1 877-912 25 2.032923 4.53 Pfam 1-43 (43) Show / Hide
Range on Protein: 877-912
Range on HMM: 1-43/43
Sequence Identity: 25% (11 aa)

VEAMYTFANIV--KNGQ--G-VQS-N-SVD-AHSSFVLAADRGH
. |.|  . .    .||  | |   .     |   . .||..||
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH