Gene 95540.m00051 (T.vaginalis)

95540.m00051

Species: T.vaginalis
Alias: 95540.m00051, TvagK0739
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: CDC15

Sequence

Name Sequence Type Origin Length Description Download
95540.m00051.AA Protein None 862 None Fasta, JSON
95540.m00051.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 95540.m00051.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95540.m00051.AA STE 35-282 29 7.6e-101 341.33 In-house 1-359 (359) Show / Hide 
Range on Protein: 35-282
Range on HMM: 1-359/359
Sequence Identity: 29% (109 aa)

LKK-EELGSGAFGVVYAAFDQ------ETSKT---------VAIKCLI-------------------NNEAIEDFQEELTLLKRLK--HPSIVPYLDSFK
... |..|.||||.|| | .       .| ..         .||| .                    |.| ......|. ..|...  || || |.... 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DS------NGALHIVMEYAENGSLLDVIK-TYGPLN-------------EMICSIYVVQILQG-LEYLHNQSIIHRDIKAANVLMQGDNCKLADFGLALD
.       .. |.|.||| ..||| |.|| .||...             | . .....|||.| |.|||.. |||||||.||.|.    .||.|||..  
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

LDK----------------YGHTLRESAGSPYWMAPEVING------DPVDTKCDIWSIGATVHELLVGKPPLWDLAPMPAMFQIA--------------
|..                 .      .|.| |||||||..      .. ||||||||.| |. |.. ||||. |. || |||.|.              
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCI

---GPRDIPI-----------------PARFSPDCKEFLQLCLNKNPKLRPDAKQLLA--HKWL
   .|  .|                  | ..||..|.|...||.|.|. ||.|.|||   |...
VNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
S_TKc 95540.m00051.AA S_TKc 34-282 35 5.3e-97 329.48 SMART 1-231 (231) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-231/231
Sequence Identity: 35% (93 aa)

FLKKEELGSGAFGVVYAAFDQETSKTVAIKCLINNEAIEDFQEELTLLKRLKHPSIVPYLDSFKDSNGALHIVMEYAEN--GSLLDVIKTYGP------L
. . ...|.||||.|| . . .| . ||||..      |... |. .||. .|| || ..|.| |  . |..||||...  |.|.|.|| .|.      .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGDNCKLADFGLALDLDKYGHTLRESAGSPYWMAPEVINGDPVDT-KCDIWSIGATVHELLVGK
.|  .  |. ||...|||.|.. |||||.| .|.|.   . |..|||||  |       .   |.|..|||||.   . .. |||.||.| .. |.|.|.
PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY

PPLWDLAPMPAMFQIAGPRDIPIPARFSPDCKEFLQLCLNKNPKLRPDAKQLLA-------HKWL
|| .    | .||.. |          ||..|.|.. ||.|.|. || | ..|.       | |.
PPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95540.m00051.AA STE11 34-282 36 6.4e-91 308.37 In-house 1-303 (303) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-303/303
Sequence Identity: 36% (110 aa)

FLKKEELGSGAFGVVYAAFDQETSKTVAIK----CLINN------EAIED------FQEELTLLKRLKHPSIVPYLDSFKD--SNGALHIVMEYAENGSL
. |.| .|.||||.||....  | . .|.|    . .|.      . ...      .|||. |.| |.|. || |...  .  .|. . | ||| ..|||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

LDVIK-TYGP--LNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGDNC--KLADFGLALDLDKYG-HTLRESA---------GSPY--------
 ....  .||  ..||  ..|. |||.|| ||| . |||||||.||.|.  |..  |||||| |  | . . .|   ..         |.||        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WMAPEVINGDP---VDTKCDIWSIGATVHELLVGKPPLWDLA--PMPAMFQIA-G-PRDIPIPARFS------PDCKEFLQLCLNKNPKLRPDAKQLLAH
|||||||.. .    ..|.||||.|.|| | . ||||  ..   .| ||| |. |    .||| ..|      ..|..||..|. ..|| || | ||| |
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

KWL
...
PFI
Kinase 95540.m00051.AA STE20 34-282 38 2.8e-89 302.92 In-house 1-288 (288) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-288/288
Sequence Identity: 38% (111 aa)

FLKKEELGSGAFGVVYAAFDQETSKT----VAIKCLINNEA------IEDFQEELTLLKRLKHPSIVPYLDSFKDS---NGALHIVMEYAENGSLLDVIK
. . |..|.|..|.|| | . .| .     |||| .  ...      .|| | |   .|..||| || |..|.  .   .  | ||||| . |||.|..|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---TYG------PLNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGD-NCKLADFGLALDLDK-----YGHTLRESAGSPYWMAPEVING----
   . |      |.||   .    ..||||.|||.. ||||||||.|.|.  | ..||||||.. .|.|      . .     |.|||||||||..    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-DPVDTKCDIWSIGATVHELLVGKPPLWDLAPMPAMFQIA----GPRDIPI--PARFSPDCKEFLQLCLNKNPKLRPDAKQLLAHKWL
  . |.|||||| | |  |.. |.||. |. || |||.|.    .| .     | ..||. ..|. .||.|.|. || |.||| |...
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 95540.m00051.AA Dicty2 34-282 44 6.1e-89 301.78 In-house 1-264 (264) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-264/264
Sequence Identity: 44% (119 aa)

FLKK-EELGSGAFGVVYAAFDQETSKTVAIKCL--------INNEAIEDFQEELTLLKRLKHPSIVPYLDSFKDSNGALHIVMEYAENGSLLDVIKTYGP
..   | .| ||||.|| . . ||   ||||          | .| .     |  |||.|.|. || |... . .|  | |..|| ||||| ..|| .|.
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETEN-HLYIILEYIENGSLSKIIKKFGC

LNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGDNC----KLADFGLALDLD-KYGHTLRESAGSPYWMAPEVINGDP--VDTKCDIWSIGATV
. |  |.||. |.|.||.||| | .||||||||| |   ..     |||||| |  .| .        .| |||||||||  .     |.||||| | |.
FPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTI

HELLVGKPPLWDLAPMPAMFQIAGPRDIPIPARFSPDCKEFLQLCLNKNPKLRPDAKQLLAHKWL
 ||| | || |||.||.||| .      |.|   ||.|| ||. | .| | .|..||||| |.|.
IELLTGNPPYWDLNPMHAMFRMVQDDHPPLPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase 95540.m00051.AA Pkinase 34-282 33 8.1e-88 302.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-293/293
Sequence Identity: 33% (98 aa)

FLKKEELGSGAFGVVYAAFDQETSKTVAIKCLINNEAIEDFQE------ELTLLKRLKHPSIVPYLDSFKDSNGALHIVMEYAENG----SLLDVIK--T
. ... .|||.||.|| . .. |.|.||.|..   .. .....      |. ..|||.|| || ..|.| | .. ...||||.|.|    .| |.|.   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWR

YGPL--NEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQ-GDNC----KLADFGLALDL-DKYGHTLRESAGSPYWMAPEVIN-GDPVDTKCDIWS
.|..   |  |  |. |||.||||.|...|||||.| .|.|.   ...    |..|||||  .    .. .   .|.|..||||||. | . ..|.|.||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGATVHELLVGKPPLWDL------APMPAMFQIAG-PRDIPIPARFS-------------------PDCKEFLQLCLNKNPKLRPDAKQLLAHKWL
.| ...|.| |.|| ..        .|  ...| | | . ..|   |                   ..||.|.  ||.|.|| || |.|.| |.|.
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95540.m00051.AA YSK 34-282 42 8.4e-83 249.08 In-house 1-257 (257) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-257/257
Sequence Identity: 42% (111 aa)

FLKKEELGSGAFGVVYAAFDQETSKTVAIKCL---INNEAIEDFQEELTLLKRLKHPSIVPYLDSF-KDSNGALHIVMEYAENGSLLDVIKTY--GPLNE
| | |  | | ||.|| . |. | ..|||| .      . ||| | | . |  .. | |  |. |. ||.   | |.|||   ||.|| .|    |.. |
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDT--KLWIIMEYCGGGSCLDLMKPKYVGQFDE

MICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGD-NCKLADFGLALDLDKYGHTLRESAGSPYWMAPEVING--DPVDTKCDIWSIGATVHELLVGK
.  .|    ||.||.||| .  |||||||||||.. . . ||.||| |  .      .   .|.|||||||||    .  |.| ||||.| |  |.. | 
KYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGE

PPLWDLAPMPAMFQIAGPRDIP--IPA-RFSPDCKEFLQLCLNKNPKLRPDAKQLLAHKWL
||. |. || .|| |  | . |       .|   |||  .||||.|. || ||.|| ||  
PPYCDYHPMRVMFLI--PKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 95540.m00051.AA CAMK 39-282 19 2.9e-76 245.09 In-house 1-425 (425) Show / Hide 
Range on Protein: 39-282
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

ELGSGAFGVVYAAFDQETS------------KTVAIKC-----LINNE-------------------------AIEDFQEELTLLKR-------LKHPSI
.||.|.||.|. ... .|             . ||||      | ...                           . .. |. ..|.       |.|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VPYLDSFKD-----------SNGA--------LHIVM---EYAENG----SLLDVIKTYGP---------------LNEMICSIYVVQILQGLEYLHNQS
.  .. . |           .           ...||   ||...|     |.| |.  |.               ..|  .. |. ||.....|.|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKAANVLMQGD------------------NCKLADFGLALDLDK-----------------------YGHTLRESAGSPYWMA-PEVING-----
|.|||.|  |.|.. .                  | |..|||.|  .|.                       .|. .... |.|. || |||.||     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------DPVDTKCDIWSIGATVHELLVGKPPLWDLAPM------------PAMFQ--IAGPRDIPIPA----------------------RFSPDCK
         .... |||.||.|     .|.|.|| ..   .            . .|.  ..|  | | |                        .|..||
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

EFLQLCLNKNPKLRPDAKQLLAHKWL
 ... .|...|. |. ..| |.|.|.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 95540.m00051.AA STE11-Unclassified 34-282 32 9.9e-76 257.9 In-house 1-308 (308) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-308/308
Sequence Identity: 32% (101 aa)

FLKKEELGSGAFGVVYAAFDQETSKTVAIKCLIN------NEAIEDF-----QEELTLLKRLKHPSIVPYLDSFK--DSNGALHIVMEYAENGSLLDVIK
. | | .|.|.|| || ... .| . .|.| .        .|....      |.|...|| | |. || |.. ..  .... . |.||| ..||.   ..
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYG-CEIHKHEDCINIFMEYMPGGSIWSMLN

TYGPLNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGD-NCKLADFGLAL----------------DLDKYGHTLRESA---------GSPY--
 ||...||  ..|. |||.||.||| ..|||||||.||.|  .| .|||.|||.|                 . | |  .. .           |.||  
KYGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQP

-WMAPEVIN---GDPVDTKCDIWSIGATVHELLVGKPPLWDLAP---MPAMF-QIAGPRDIPIPARFS-----------PDCKEFLQLCLNKNPKLRPDA
 |||||||.    .  ..| ||||.| || |   ||.|  .. .   | |..  ..  . ..|| . |           ..||.||..|.  .|| ||.|
FWMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTA

KQLLAHKWL
 ||| |...
NQLLQHPFI
Kinase 95540.m00051.AA PAKA 34-282 37 1.8e-67 230.5 In-house 1-260 (260) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-260/260
Sequence Identity: 37% (97 aa)

FLKKEELGSGAFGVVYAAFDQETSKT--VAIK--CLINNEAIEDFQEELTLLKRLKHPSIVPYLDSFKDSNGALHIVMEYAENGSLLDVIKTYG-----P
. . |..| || | || | . .| ..  ||||   . |.  .|    |. ..|  ||. || |.||..  .  | .|||| | |.| |||. .      .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVMKECKHKNIVNYIDSYLV-DDELWVVMEYMEGGCLTDVITQCCNIQCNY

LNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGD-NCKLADFGLALDLDKYGHTLRESAGSPYWMAPEVINGDPVDTKCDIWSIGATVHELLVG
..| . .  . ..|||||..|....||||||  |.|.  | . |..||| .  | .         | |||||||||..   | | ||||.|  . |.. |
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

KPPLWDLAPMPAMFQIA--GPRDIPIPARFSPDCKEFLQLCLNKNPKLRPDAKQLLAHKWL
 ||  .  |  ||. ||  |  ||  |...|.. ..|| .||..... |..|..||.|  |
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 95540.m00051.AA ULK 34-282 27 3.1e-67 229.67 In-house 1-324 (324) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-324/324
Sequence Identity: 27% (91 aa)

FLKKEELGSGAFG-VVYAAFDQET---SKTVAIKCLI-------NNE-----AIEDFQEELTLLKRLK---HPS--IVPYLDSFKDSNG-ALHIVMEYAE
. ....||.|.|| .|| .....|    . ||.|.         .||     ... .. |  ..| ||   ||   || ..| |..||   . |.||| .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGSLLDVIKTYGP---------LNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGDN-------------CKLADFGLALDLD------KYGHT
 | | . ||....         |.|... ..  ||..|. .||.. ||||||| .| |.  ..             .|.||||.|  .|         .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

LR-ESA---GSPYWMAPEVINGD----PVD-TKCDIWSIGATVHELLVGKPP--LWDLAPMPA------------MFQIA-GPRDIPIPA---RFSPDCK
.  |     |.|. |||....|     | .  ||||||.|   .|.| ||.|   |   .               ...|   | ..|.|     .||.||
CVNE-KRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

EFLQLCLNKNPKLRPDAKQLLAHKWL
.... .| ...| | .  ....|.|.
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 95540.m00051.AA ULK 34-282 26 3.3e-67 229.59 In-house 1-329 (329) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-329/329
Sequence Identity: 26% (89 aa)

FLKKEELGSGAFGVVYAAFDQET----SKTVAIKCLI----NNEAIED--------FQEELTLLKRLK--------HPSIVPYLDSFKDSNG-ALHIVME
. ....||.|.||.|| .....|     . ||.| .     |..  |.        .. |  ..|.||        || || ..| |..||   . |.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAENGSLLDVIKTYGP----------LNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGDN-------------CKLADFGLALDLDKY---GH
| . | | . ||....          |.|... ..  |||.|. .|| . ||||||| .|.|.  ..             .|.||||.|  .|.      
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

TLRESA------GSPYWMAPEVINGD----PVD-TKCDIWSIGATVHELLVGKPP--LWDLAPMPAMFQIAGPRD----------IPIPAR-------FS
 .          |.|. |||....|     | .  ||||||.|   .|.|.||||   |   .   ....   ..          .|.  .       .|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PDCKEFLQLCLNKNPKLRPDAKQLLAHKWL
|.||.... .| ...| | .  .|..|.|.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 95540.m00051.AA Pkinase_Tyr 34-279 30 2.6e-36 123.6 Pfam 1-269 (270) Show / Hide 
Range on Protein: 34-279
Range on HMM: 1-269/270
Sequence Identity: 30% (84 aa)

FLKKEELGSGAFGVVYAAFDQ----ETSKTVAIKCL--INNEA---IEDFQEELTLLKRL-KHPSIVPYLDSFKDSNGA--LHIVMEYAENGSLLDVIKT
  . ..||.||||.|| .       .|  .||.|.|     .    .||| .|. ..| | .|| || ..    |  .   . |||||...|.|||  ..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

Y----GPLNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQ-GDNCKLADFGLALDL---DKYGHTLRESAGSPY-WMAPEVINGDPVDTKCDIWS
     .||.      . .|| .|.|||... .||||. | |.|   .  .| .||||| |.   | | .. |...  |  |||||.||     || |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

IGATVHELLV-GKPP-LWDLAPMPAMFQI--AGPRDIPIPARFSPDCKEFLQLCLNKNPKLRPDAKQLLAH
 | .  |..  |. |  ... .   . .|   | |  |.|   ...  . ...| ...|. ||  .... .
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR-MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQ
Kinase 95540.m00051.AA TyrKc 34-282 26 1.1e-35 125.78 SMART 1-280 (280) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-280/280
Sequence Identity: 26% (77 aa)

FLKKEELGSGAFGVVYAAFDQETSKTVAIKCLINNEAIEDFQEELTLLKRL--KHPSIVPYLDSFKDSN------GALHIVMEYAENGSLLDVIKTYGP-
  ....||.||||.|| .       .||.|.| ..  .||| .|. ....|  .|| ||  .    ..       . | |||||...|.|.| .. ..| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LNEMICSIYVVQILQGLEYLHNQSIIHRDIKAANVLMQGDN-CKLADFGLALDLDKY------GHTLRESA--GSP-----YWMAPEVINGDPVDTKCDI
|.      . .|| .| |||| . .||||. | |.|   .. .| .||||. |.. .      . . | .   |.       |||||.||     || |.
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

WSIGATVHELL-VGKPPLWD-----LAPMPAMFQIAGPRDIPIPAR--------FSPDCKEFLQLCLNKNPKLRPDAKQLLAHKWL
|| | .  |..  |..| ..     . .  .. ..   .  |.|.          ...  .  . | . .|. ||  ...  |. .
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF