Gene 88200.m00230 (T.vaginalis)

88200.m00230

Species: T.vaginalis
Alias: 88200.m00230, TvagK0592
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
88200.m00230.AA Protein None 383 None Fasta, JSON
88200.m00230.kin_dom Protein Kinase Domain None 289 None Fasta, JSON

Protein domain

Protein domains of 88200.m00230.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 88200.m00230.AA CDK 21-309 33 6.6e-98 313.83 In-house 1-284 (284) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-284/284
Sequence Identity: 33% (109 aa)

FTFVENIGKGTYATVSKCIDKATN-----KPVALKAIKKVT-----DEDGFTKTTLREIRLLQKLNHENIVKLQKVLICK-----------GTIYLVLEY
.  .| || |||..| |..|| |.     . |||| |.  .     ...||  |..||| ||..| |.|||||  | . |            ..|.| ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CQYDLSALLHRKNAPHLSERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNV-----LKLGDFGLARDIML-------NKRFTSKVITQWYRPP
. .||. ...           |||. .||.  | |.  ....||||||.|. |..| .     ||..||||||           |. .|..|.| |||.|
MDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

ELLFGCSEYG--IEVDIWSAACIFYEIIT---KKPLFYTQDTNNELAQLIRIFKICGMSEESRFMGYDLWRMIQPHLSQFPPPSNLKIYLEKTIPKNYHE
|||.|...|.   ..|.||. |||.|..|   .||||     ..|. || .||.|||   |.   |                                  
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLF---PGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY---------------------------

IINLLLAMLRFNPKKRPTPSAILD-QYF
  .||  || ..|||| . .. |. .||
--DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 88200.m00230.AA CMGC 21-309 21 1.2e-93 308.05 In-house 1-513 (513) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

FTFVENIGKGTYATVSKCIDKATNKP--------------VALKAIKKVTDEDGFTK----------TTLREIRLLQKLN-----------------HEN
.. .. ||.|||..| ||.|| ||..              ||.| ||..  ..   |          ..||||..|..||                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKLQKVLICKG-----------------TIYLVLEYCQYDLSALLHRKNAP-------HLSERF------------IKCIQ------FQLMVCLR--YL
||||. ..  |.                  .||| ||...||  ...... .       .|||              ||..       .|.  .|   |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

DTQR--VIHRDLKPANLFITENNVL--------------------KLGDFGLARDIMLNKR----------------------FTSKVITQWYRPPELLF
  ..  .|||||||.|. |..|. |                    |..|||||| .  ...                      .|. | | |||.||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GC---------SEYGIEVDIWSAACIFYEIITK--------KPLFYTQDT--------NNELAQLIRIFKICGMSE---------------ESRFMGYDL
|.          .|. ..|.||..|||.|..|.        |||| ...         .... || .|||..|.                 |  ....  
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

WRMIQPHLS---------QFP------------PPSNLKIYLEKTIPKNY-----------------------------------HEIINLLLAMLRFNP
    .....         ...             |   .. ... .|..                                    .. |.||  ||...|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

KKRPTPSAILD-QYF
.||.|.. .|.  ||
DKRITAEQALQHPYF
Kinase 88200.m00230.AA CDC2 21-309 34 7.8e-85 260.59 In-house 1-301 (301) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-301/301
Sequence Identity: 34% (107 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTDEDG--FTKTTLREIRLLQKLN-HENIVKLQKVLICKGTIYLVLEYCQYDLSALLHRKNAP--H
.. .| ||.|||  | ||.|. ||. |||| |.  ....|  .  |..||| .|..|. |.|||||. |...   .|.| ||. .||  .. ... .  |
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LSERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIMLNKR-FT--SKVITQWYRPPELLFGCSEYGIEVDIWSAACIFYEI
... ..| . .|.   . .. ..|..|||||| |..| .. ..|..||||||..  ..|  |    |.| |||.||.|.||. | ..||.||  |||.|.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---ITKKPLFYTQDTNNELAQLIRIFKICGMSEESRFMGYDLWRMIQPHLSQFPPPSNLKIYLEK-TIPK----NYHEIINLLLAMLRFNPKKRPTPSAI
   .||||||  .    |  || .||.| |   |. ..| .     ..   ...| ..|......   .|    . .| | ||  ||. .| || .  ..
FMDVTKKPLFHGD---SEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKP-QDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEA

LD-QYF
|.  ||
LQHPYF
Kinase 88200.m00230.AA S_TKc 21-309 27 1.1e-82 281.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-231/231
Sequence Identity: 27% (84 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTDEDGFTKTTLREIRLLQKLNHENIVKLQKVLICKGTIYLVLEYCQY---DLSALLHRKNAPH--
..... ||||....| ||..| |.. ||.| ||         ....|||..|.| .|.|||||  |    . .|.|.|||     ||  ...... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIMLNKRFTSKVITQWYRPPELLFGCSEYGI-EVDIWSAACIFYEI
  ..|  ....  |.   | |.  ...|||||||.|....|  ..|..|||||| .      |. . | ||..||.|     ||  ..|.||  ||.|| 
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

ITKKPLFYTQDTNNELAQLIRIFKICGMSEESRFMGYDLWRMIQPHLSQFPPPSNLKIYLEKTIPKNYHEIINLLLAMLRFNPKKRPTPSAILD------
.. .|.|.         |. ..||..|                                         .| ....  .|...|.||||   .|       
LCGYPPFP---------QMQMMFKKIG----------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

--QYF
  ..|
CHPWF
Kinase 88200.m00230.AA Pkinase 21-309 30 5.6e-75 260.19 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-293/293
Sequence Identity: 30% (95 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTDEDGFTKTTLR--EIRLLQKLNHENIVKLQKVLICKGTIYLVLEYCQY-----DLSALLHRKNA
..... ||.|....| ||..| |.| ||.| |||....... .| .|  ||.....|||.|||.|  .   |. ||.|.|||.      ||........ 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PHL--SERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVL----KLGDFGLARD--IMLNKRFTSKVITQWYRPPELLFGCSEYGIEVDIWSA
  .  ||. .|..  |.   | |.  ...|||||||.|..| .|...    |..|||||.   .  |  .|. . | ||..||.. |...|| .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

ACIFYEIITKKPLFYTQ-DTNNELAQLIRIFKICG---------MSEESRFMGYDLWRMIQPHLSQFPPPSNLKIYLEKTIPKNYHEIINLLLAMLRFNP
 ||.|| ....|.|. . .. | . |. .|..| |          ...|.|.     .                . ...  ..   | . ..  .|...|
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------------F-HWTF-HNWSEECKDFIKWCLCKDP

KKRPTPSAILDQ-YF
|||||.  ||   .|
KKRPTAEQILQHPWF
Kinase 88200.m00230.AA CDK7 21-239 37 9.3e-72 190.23 In-house 1-220 (288) Show / Hide 
Range on Protein: 21-239
Range on HMM: 1-220/288
Sequence Identity: 37% (85 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIK----KVTDEDGFTKTTLREIRLLQKLNHENIVKLQKVLICKGTIYLVLEYCQYDLSALLHRKNAPHL
.. .. || |..|||.|  |..|.. || | ||    .   .||   | .||| .|| . |.|.. |  ..  |  |.||... . ||      |    |
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSI-IL

SERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIML-NKRFTSKVITQWYRPPELLFGCSEYGIEVDIWSAACIFYEIITK
    || .  ..   | |.    . |||||| || . || .||..|||||| .   |. .|..|.| ||| ||||||   ||  ||.||  ||| | .  
TPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLR

KPLFYTQDTNNELAQLIRIFKICG
 | .  .   ... || |||.. |
VPYLPGD---SDIDQLTRIFQTLG
Kinase 88200.m00230.AA CDK5 21-309 36 7.3e-70 219.79 In-house 1-287 (287) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-287/287
Sequence Identity: 36% (107 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTDEDGFTKTTLREIRLLQKLNHENIVKLQKVLICKGTIYLVLEYCQYDLSALLHRKNAPHLSERF
.  .| || |||.|| |  .| |   |||| ..   .  |   | .||| ||. | |.||| |  |.     . || |.|  ||   .   |   .. . 
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG-EMDMHI

IKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIMLN-KRFTSKVITQWYRPPELLFGCSEYGIEVDIWSAACIFYEII-TKKPL
|| ...||.  | .   ..| |||||| || |  |  |||.||||||      . ... |.| |||||  |.|   |   .|.||. ||| |.. . .||
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPL

FYTQDTNNELAQLIRIFKICGMSEESRFMGYDLWRMIQPHLSQFPPPSNLKIYLEKTIPKNYHEIINLLLAMLRFNPKKRPTPSAILD-QYF
|     |..  || ||||| |   |..  .       .|   |.| . ...  ... .||   .  .||  ||..||..| .  | |  .||
F---PGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYP-MYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 88200.m00230.AA CRK7 21-239 34 1.5e-62 214.09 In-house 1-270 (343) Show / Hide 
Range on Protein: 21-239
Range on HMM: 1-270/343
Sequence Identity: 34% (95 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTD---EDGFTKTTLREIRLLQKLNHENIVKLQKVLICK----------GTIYLVLEYCQYDLSAL
.  .. || |||  | |  .| |.. |||| ..   .   ..||  |  |||..|. |||.|||.|  . . |          |..|.| ||   ||. |
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIVNLKEIVTDKQDASEFKKHKGSFYMVFEYMDHDLMGL

LHRKNAPHLSERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIMLNK---RFTSKVITQWYRPPELLFGCSEY--------
|  |   | |.  .||.  ||.  . |.  . ..|||.| .|. .  .  .|. ||||||    .     .| .||| |||||||| |  .|        
LESKEMHHFSHQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKE

------------------------------GIEVDIWSAACIFYEIITKKPLFYTQDTNNELAQLIRIFKICG
                              | |.|.||  ||. |  ||||.|     |||.|||  |.||||
LIRNIKSIQLSLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIF---QGNNEMAQLEKIYKICG
Kinase 88200.m00230.AA MAPK 21-300 30 8.7e-62 211.58 In-house 1-318 (328) Show / Hide 
Range on Protein: 21-300
Range on HMM: 1-318/328
Sequence Identity: 30% (100 aa)

FTFVENIGKGTYATVSKCIDKA------TNKPVALKAIKKVTDEDGFTKTTLREIRLLQKL-NHENIVKLQKVLICK-----------GTIYLVLEYCQY
.. ...||.| | .| ..|||       ..| ||.| | .. .   ..| |.|||.||. . .||||.||. ..  .            .||.| |... 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLSALLHRKNAPHLSERFIKCIQFQLMVC--LRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIMLN---------------KRFTSKVITQWYR
|| ..... .  .||.  |. . .|.     | |.   .||||||||.|. ..||  ||..|||||| |  .               .  |  | |.|||
DLHQIIKSQQ--PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYR

PPELLFG--CSEYGIEVDIWSAACIFYEIIT-KKPLFYTQDTNNELAQLIRIFKICGMSEESRF--MG-YDLWRMIQPHLSQFP-PPSNLKIYLEKTIPK
 ||....    .|   ||.||. ||| | .|  ||||     .. . |. .|....|. .|     .. ..  |     ..... .|   |. .|| .|.
APEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFP---GKDYIDQWNLIMEVLGTPSEEFIQCICMSEHARNY---IQSLGNLPKYPKKPWEKMFPN

----NYHEIINLLLAMLRFNPKKRPT
      .. |.||  || |.|.|| |
ANFNANPQAIDLLEKMLVFDPDKRIT
Kinase 88200.m00230.AA CDK10 21-309 35 4.5e-60 205.88 In-house 1-285 (285) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-285/285
Sequence Identity: 35% (105 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTDEDGFTKTTLREIRLLQKLNHENIVKLQKVLICK--GTIYLVLEYCQYDLSALLHRKNAPHLSE
|  .  .| |||  | .  |  ..  |||| ..   . ||     |||| || .. |||||.|. | . .    |.||..||  || .||     |  .|
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQP-FTE

RFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIML-NKRFTSKVITQWYRPPELLFGCSEYGIEVDIWSAACIFYEIITKKP
  .|||  |..  |.||  . .|||||| .|| .|..  .|. ||||||   .  |  | |..| ||| ||||.|| .    .|.| . ||  |.. .||
TQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKP

LFYTQDTNNELAQLIRIFKICGMSEESRFMGYDLWRMIQPHLSQFPPPSNLKIYLEKTIPKNYHEIINLLLAMLRFNPKKRPTPSAILD-QYF
|.     | |..|.  | .. |  .|. . |.    |.| .  .  |  |||   .  . .   ...|.|.    .||||| |    |. .||
LM---PGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFH-WLSQSGRRLLNFLFM---YNPKKRATAEECLESSYF
Kinase 88200.m00230.AA PITSLRE 21-309 35 1.7e-55 190.72 In-house 1-295 (295) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-295/295
Sequence Identity: 35% (108 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKV--TDEDGFTKTTLREIR-LLQKLNHENIVKLQKVLICKGT--IYLVLEYCQYDLSALLHRKN--A
|  .  |. |||  |..  || |.  |||| .|     . .||  | ||||  .|  |.|.|||..  ... .    ||.|.||   ||  |.   .   
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRN

PHLSERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIMLN-KRFTSKVITQWYRPPELLFGCSEYGIEVDIWSAACIFYEI
   ..  |||   ||     ..    ..||||| .|| .. . .||..||||||    . | .|. |.| ||| |||| || .|   ||.||  ||| |.
QPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEF

ITKKPLFYTQDTNNELAQLIRIFKICGMSEES---RFMGYDLWRMIQPHLSQFPPPSNLKIYLE--KTIPKNYHEIINLLLAMLRFNPKKRPTPS-AILD
||.||||     ..|. |. .|||  |   |.    .   ..|.|..  ... | ..||.      ..|  .  .   ||  || .|||.| | | |. .
ITMKPLF---QGKSEIDQINCIFKEMGTPTEKIWPGWTELPHWKMMNN-FPHYP-YNNLRKRFPAENHISDTGFD---LLNQMLTYNPKNRITASDALKH

QYF
 .|
PWF
Kinase 88200.m00230.AA PFTAIRE 21-309 33 2.4e-54 186.88 In-house 1-287 (287) Show / Hide 
Range on Protein: 21-309
Range on HMM: 1-287/287
Sequence Identity: 33% (99 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTDEDGFTKTTLREIRLLQKLNHENIVKLQKVLICKGTIYLVLEYCQYDLSALLHRKNAPHLSERF
.  .|  | |.|||| | | . ... |||| | .  .| |   |  ||  ||. | | ||| |  .   | |  .| || . ||.  . . .   .  . 
YEKLEKLGEGSYATVYKGISCINQQFVALKEI-RLQQEEGTPFTAIREASLLKNLKHANIVCLHDIIHTKETLTFVFEYVHTDLCQYMDKHPG-GMHPNN

IKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIML-NKRFTSKVITQWYRPPELLFGCSEYGIEVDIWSAACIFYEIITKKPLF
..   |||.  | |   .|| |||||| || |..   ||| ||||||      . . . |.| |||||  | |  ||  ..|.| . ||| | .. .|.|
VRLFLFQLLRGLSYCHQRRVLHRDLKPQNLLISHCGELKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTHLDMWGVGCIFVEMMWGQPAF

YTQDTNNELAQLIRIFKICGMSEESRFMGYDLWRMIQPHLSQ--FPPPSNLKIYLEKTIPKNYHEIINLLLAMLRFNPKKR-PTPSAILDQYF
    .  .  || .|||. |   | .. |       .||  .  |. | .|.  ...   ..  .  .|.  ||. .|..|  .  |.  .||
PGMKDITD--QLEKIFKVLGTPTEDTWPGVCHLPNYKPHWFRGRFYKPKKLCHQWPRI--YYIPHAEDLMMKMLQCEPRDRVSAQEAMQHPYF
Kinase 88200.m00230.AA Pkinase_Tyr 21-204 31 2.8e-20 69.32 Pfam 1-199 (270) Show / Hide 
Range on Protein: 21-204
Range on HMM: 1-199/270
Sequence Identity: 31% (63 aa)

FTFVENIGKGTYATVSKCIDK----ATNKPVALKAIKKVTDEDG-FTKTTLREIRLLQKL-NHENIVKLQKVLICK-GT--IYLVLEYCQY-DLSALLHR
 || . .|.| . .| |.. |     |. ||| | .|  ....  . .  .||.... .| .|.|||.|  | ... .   ||.|.||... ||   |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K--NAPHLSERFIKCIQFQLMVCLRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDI----ML-NKRFTSKVITQWYRPPELLFGCSEYGIEVDIW
.  . ..|.   . .. .|    . ||  .. |||||   |  .||||| | .||||||||        ||  .|.   |. .|| .. .  . .. |.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM-APECINYGK-FTTKSDVW

S
|
S
Kinase 88200.m00230.AA TyrKc 21-308 20 3.5e-15 22.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-308
Range on HMM: 1-280/280
Sequence Identity: 20% (67 aa)

FTFVENIGKGTYATVSKCIDKATNKPVALKAIKKVTDEDGFTKTTLREIRLLQKL--NHENIVKLQKVLICK-------GTIYLVLEYCQY-DLSALLHR
 |. . .| | . .| |.. |    .|| | .|. .      .  .||.|.. ||  .|.|||.|  | . .       . ...|.||. . ||   |..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KNAPHLSERFIKCIQFQLMVC--LRYLDTQRVIHRDLKPANLFITENNVLKLGDFGLARDIMLN-------KRFT------SK--VITQWYRPPELLFGC
.          . ..| . ..   .||  ...|||||   |  ..||.. | .||||.|||          .  .      .|  .   |. .|| .. .
HRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECINYG

SEYGIEVDIWSAACIFYEIITKKPLFYTQ-----DTNNELAQLIRIFKICGMSEE----SRFMGYDLWRMIQPHLSQFPPPSNLKIYLEKTIPKNYHEII
 .. .. |.||     .|| |     |        .| |. ....  .     ..    |                                .    |. 
-KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------------FVCCPDEMY

NLLLAMLRFNPKKRPTPSAILDQY
.. .   ...|..||| |.| .. 
QIMKQCWHEDPEDRPTFSEIHECF
Kinase 88200.m00230.AA CDK7 282-309 34 0.006033 3.2 In-house 260-288 (288) Show / Hide 
Range on Protein: 282-309
Range on HMM: 260-288/288
Sequence Identity: 34% (10 aa)

EIINLLLAMLRFNPKKRPTPSAILD-QYF
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DLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 88200.m00230.AA CRK7 282-309 41 0.006854 5.57 In-house 315-343 (343) Show / Hide 
Range on Protein: 282-309
Range on HMM: 315-343/343
Sequence Identity: 41% (12 aa)

EIINLLLAMLRFNPKKRPTPSAILD-QYF
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ECLDLLDKMLCLDPKKRFTAEECLQHDWF