Gene 86168.m00004 (T.vaginalis)

86168.m00004

Species: T.vaginalis
Alias: 86168.m00004, TvagK0891
External Links:
Annotation:

Classification

Group: Other
Family: Other-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
86168.m00004.AA Protein None 199 None Fasta, JSON
86168.m00004.kin_dom Protein Kinase Domain None 181 None Fasta, JSON

Protein domain

Protein domains of 86168.m00004.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 86168.m00004.AA ULK 96-196 29 1.4e-18 61.57 In-house 132-254 (329) Show / Hide 
Range on Protein: 96-196
Range on HMM: 132-254/329
Sequence Identity: 29% (36 aa)

ALHIAKHILCGLYQLYSHGYIWLDCNPRNILMSDN------------MIPQFTDIGNASKVDNSNELQDIDKNKTI-----CTPLYAAPEVILYY----K
|... |.|| |.  |..|..|  |  | |||....            ..   .| | | .|||.|. |.. .  .      .|||| ||...       .
AIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKP

AS-YKSDIFSWGVLLYQLLTQKY
 . ||.||.| |...|..|. |.
YYDYKCDIWSLGCIFYEMLYGKP
Kinase 86168.m00004.AA Ciliate-E2-Unclassified 7-196 21 6.5e-17 55.21 In-house 1-268 (352) Show / Hide 
Range on Protein: 7-196
Range on HMM: 1-268/352
Sequence Identity: 21% (57 aa)

IDDFSFIGNGSEGSVYRIDEDN-----AIKILKKPDQITLETQKTIYDELSKE--EICYI------------------IPSYDVLYINDSFG------LT
      ||.|. |.||.  ...     |.|..||  ..    ...   |.. |  |.. .                  .|.  ...  . |       . 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MKFFPY-NLETLINE-------------------GISIRDAL-----HIAKHILCGL-YQLYSHGYIWLDCNPRNILMSDNM---IPQFTDIGNASKVDN
| .... .|.  |..                    .. . |.     .....||.|| |  .... |  |  | |||...|.    .  .| |...| ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

SNELQDI-----------DKNKTIC-TPLYA----APEVILY--YKAS--YKSDIFSWGVLLYQLLTQKY
.|. .             .. .|.| || |     ||||.    |  |  ||.||.| ||.||..|...|
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYY
Kinase 86168.m00004.AA ULK 96-196 29 2.7e-15 50.76 In-house 128-250 (324) Show / Hide 
Range on Protein: 96-196
Range on HMM: 128-250/324
Sequence Identity: 29% (36 aa)

ALHIAKHILCGLYQLYSHGYIWLDCNPRNILMSDN------------MIPQFTDIGNASKVDNSNELQDIDKNKTI-----CTPLYAAPEVILYY----K
|... |.|. |.  |..|..|  |  | |||....             .   .| | | .||| |. |.. .         .|||| ||...       .
AIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKP

AS-YKSDIFSWGVLLYQLLTQKY
 . ||.||.| |...|..|. ||
YYDYKCDIWSLGCIFYEMLYGKY
Kinase 86168.m00004.AA Ciliate-E1 13-182 20 2.8e-15 46.54 In-house 1-202 (202) Show / Hide 
Range on Protein: 13-182
Range on HMM: 1-202/202
Sequence Identity: 20% (42 aa)

IGNGSEGSVYRI--DEDN----AIKILKKP---DQITLETQKTIYDELSKEEI--CYIIPSYDVLYINDSFGL--TMKFFPYNLETLIN-----------
|||||.. |...  ...|    |.|| .     .|.... ..  |... |  .  ||||  .|...| .. .    . .  ..|.  ..           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

--EGISIRDA--LHIAKHILCGLYQLYSHGYIWLDCNPRNILMSDNMIPQFTDIGNAS---KVDNSNELQDIDKNKTICTPLYAAPEV--ILYYKASYKS
  . ..  .   ..|..... || .|.... | .| .| ||| ... . ...|.| ..   . .|..  ..  ...  ... |  ||.  .  .| .|||
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKS

DIF
||.
DIY
Kinase 86168.m00004.AA Ciliate-E2 13-196 20 1.1e-14 46.75 In-house 7-294 (365) Show / Hide 
Range on Protein: 13-196
Range on HMM: 7-294/365
Sequence Identity: 20% (61 aa)

IGNGSEGSVYRI--DED--------------------------NAIKILKKPDQITLETQKTIYDELS------KE----EIC---YIIPSYDVLY--IN
||.|. ||||.   ...                           |.||.|| . . ..  . |. |.       .|    |.    .||  |.. .   .
IGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDD

DSFGLTMKFFPY-NLETLINEG-------------ISIRDALHIAKHILC---------------GLYQLYSHG-YIWLDCNPRNILMSDNMIPQFTDIG
... | | .. . .|. .|..              .... ...| |.||                .|  | | .  |  |  | |||.     .  .| |
NNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFG

NASKVDNSNE---------LQDIDK-------------------NKTICTPLYAAPEVILYYK---------ASYKSDIFSWGVLLYQLLTQKY
.. |.|..|.         .    |                   | ...|| | |||.. . |          .||.||.| ||.||..|. |.
LSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP
Kinase 86168.m00004.AA AGC 124-193 20 9.1e-12 25.2 In-house 185-300 (395) Show / Hide 
Range on Protein: 124-193
Range on HMM: 185-300/395
Sequence Identity: 20% (24 aa)

NILMSDNMIPQFTDIGNASKVDNSNELQ---------------------------------------------DIDKNKTIC---TPLYAAPEVILYYKA
|||. ..     || | . .. |..| .                                             . |...|.|   || | |||..     
NILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----Y

SYKSDIFS--WGVLLYQLLT
..  |. |   |.|.|..||
GKACDWWSFGLGCLMYEMLT
Kinase 86168.m00004.AA TKL 121-195 20 1.6e-11 37.78 In-house 167-286 (364) Show / Hide 
Range on Protein: 121-195
Range on HMM: 167-286/364
Sequence Identity: 20% (24 aa)

NPRNILMSDNMI--------------PQFTDIGNASKVDNSNELQDID--------------KNKTIC-TPLYAAPEVILY----------------YKA
...|||  .|.               .  .| | .  ...|.. .|.               .. |.| || . ||||.                  ...
KSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEY

SYKSDIFSWGVLLYQLLTQK
| |.|..|.|..|. .|| .
SEKCDVYSFGIVLWEILTRC
Kinase 86168.m00004.AA DRAK 89-193 29 2.1e-10 27.98 In-house 94-196 (259) Show / Hide 
Range on Protein: 89-193
Range on HMM: 94-196/259
Sequence Identity: 29% (32 aa)

EGISIRDALHIAKHILCGLYQLYSHGYIWLDCNPRNILMSDNMIPQ---FTDIGNASKVDNSNELQDIDKNKTICTPLYAAPEVILYYKASYKSDIFSWG
|... .|. .. . || |.. | .   . ||  | |||..   .       | | . .. |. |. .|       || | |||.  |   .   |. | |
ECFCEKDVQRCMRQILEGVHYLHQRNIVHLDLKPQNILLTSEYPEDDIKICDFGMSRYICNGEEVREI-----MGTPDYVAPEILNYDPITMATDMWSIG

VLLYQLLT
|| | .||
VLTYVMLT
Kinase 86168.m00004.AA Pkinase 90-195 30 2.5e-10 37.59 Pfam 102-209 (293) Show / Hide 
Range on Protein: 90-195
Range on HMM: 102-209/293
Sequence Identity: 30% (35 aa)

GI--SIRDALHIAKHILCGLYQLYSHGYIWLDCNPRNILMSDNMIP----QFTDIGNASKVDNSNELQDIDKNKTIC-TPLYAAPEVIL-YYKASYKSDI
..  | ... .... ||.||. ..|.| |  |  | |||...|. .      .| | | ..|    .     ..|.| || |.|||||. . . ..|.|.
CFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

FSWGVLLYQLLTQK
.| |..||..|. .
WSCGCILYEMLCGR
Kinase 86168.m00004.AA SAK 94-193 32 2.7e-10 31.0 In-house 100-195 (254) Show / Hide 
Range on Protein: 94-193
Range on HMM: 100-195/254
Sequence Identity: 32% (33 aa)

RDALHIAKHILCGLYQLYSHGYIWLDCNPRNILMSDNMIPQFTDIGNASKVDNSNELQDIDKNKTIC-TPLYAAPEVILYYKASYKSDIFSWGVLLYQLL
..| |. ..|. |.  | ||| .  |    |||.. .|  .  | | |...   .|     |  |.| || | .||..       .||..| | .|| ||
EEARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHE-----KHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLL

T
.
I
Kinase 86168.m00004.AA Ciliate-E3 119-192 30 6.1e-10 27.48 In-house 128-202 (202) Show / Hide 
Range on Protein: 119-192
Range on HMM: 128-202/202
Sequence Identity: 30% (25 aa)

DCNPRNILMSDNM---IPQFTDIGNASKVDNSNELQDIDK--NKTI---CTPLYAAPEVILYYKASYKSDIFSWGVLLYQLL
| .| ||| . |    | .. | | . .  .       .|  . |    .||.|||||.  . . |  ||. | |. . || 
DIKPDNILVDKNNNQLIIKICDFGESKQLRK-------NKGHTHTQYQGWTPFYAAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase 86168.m00004.AA S_TKc 7-197 20 1.5e-09 -37.07 SMART 1-231 (231) Show / Hide 
Range on Protein: 7-197
Range on HMM: 1-231/231
Sequence Identity: 20% (53 aa)

IDDFSFIGNGSEGSVYRIDEDN-----AIKILKKPDQITLETQKTIYDE---LSKEEICYIIPSYDVLYINDSFGLTMKFFPY---NLETLINEG-----
 .    || |. |.||.  . .     ||||.|          ..|. |   |.|    .|.  ||| .  |.. . | . .    .| ..| .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ISIRDALHIAKHILCGLYQLYSHGYIWLDCNPRNILMSDNMIPQFTDIGNASKVDNSNELQDIDKNKTICTPLYAAPEVILYYKASY-KSDIFSWGV
   ..  .| .... |.|.|  . ||| |  |  | |||...      .| | | ..           .  . || | ||||.   . .. |.|. | |.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

LLYQLLT-------------------------------------------------QKYA
.|| .|.                                                   . 
ILYEMLCGYPPFPQMQMMFKKIGSPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase 86168.m00004.AA Pkinase 7-23 41 7.479254 0.56 Pfam 1-17 (293) Show / Hide 
Range on Protein: 7-23
Range on HMM: 1-17/293
Sequence Identity: 41% (7 aa)

IDDFSFIGNGSEGSVYR
.   . || || |.||.
YHIGRKIGSGSFGCVYK