Gene 82181.m00150 (T.vaginalis)

82181.m00150

Species: T.vaginalis
Alias: TvagK0839, 82181.m00150
External Links:
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MOK

Sequence

Name Sequence Type Origin Length Description Download
82181.m00150.AA Protein None 451 None Fasta, JSON
82181.m00150.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of 82181.m00150.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82181.m00150.AA RCK 6-290 42 8.3e-136 433.54 In-house 2-298 (298) Show / Hide 
Range on Protein: 6-290
Range on HMM: 2-298/298
Sequence Identity: 42% (126 aa)

RIIAKLGEGSFAEVYKVKNPKTQQVFAIKRLKKRYRTIEEVNKLPEVQYLKALQGHPNIIKLYEVIYNSQDGYVALLFELMDVNLYEFVRD---NQKPCD
 ||..||.|.. .| | .| .|... |||..|......||...|.|.. |..|  |||||||.|||... ..  .. ||.|| |||.. .|    .|.  
QIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYLP

EKT--TLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKA--------TLELKLCDFGSTRAVSNSGPYTEYVSTRWYRAPECILTSGSYGREVDIWAVG
|..      .||.|..|..||... ||||.|||| |...         .  .|..|||. | . .  |||.||||||||||||.|... |   .||||||
ENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVG

CMLYELLTTRPLFPGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGKMLIYNPADRITAHDALLHPAF
|  ||| . ||||||  |||||  |... |||.   .....|  . |. | |||  .. | ..|| .|.....|| ||| ..|  ||||. || || |
CIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLAS-QMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF
Kinase 82181.m00150.AA MOK 6-290 44 7.50000000001e-117 367.9 In-house 2-283 (283) Show / Hide 
Range on Protein: 6-290
Range on HMM: 2-283/283
Sequence Identity: 44% (127 aa)

RIIAKLGEGSFAEVYKVKNPKTQQVFAIKRLKKRYRTIEEVNKLPEVQYLKALQGHPNIIKLYEVIYNSQDGYVALLFELMDVNLYEFVRDNQKPCDEKT
. | |.|||.|.|| |..  .  . .| |..|... .||.||.| |.| .. |. ||||..| ||..  . | .||. ||||.|.|| .|    .  .| 
KAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQKK

TLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVSNSGPYTEYVSTRWYRAPECILTSGSYGREVDIWAVGCMLYELLTTRPLF
  . .|||.|.|| ||   .||||||||| .. .    ||| |||| |.|    |||||.||||||||||.|| | |  ..|.|.|||. ||..  .|||
IMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDH--LKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLF

PGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGKMLIYNPADRITAHDALLHPAF
||  |.||||.|| ..|||   .||.|. |    ... || .    . |..| ... ....| ||  | | .||||| .. || |
PGVNEVDQISKIHDVMGTPCQKILNKFK-NQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase 82181.m00150.AA CMGC 5-290 22 6.1e-111 365.96 In-house 1-513 (513) Show / Hide 
Range on Protein: 5-290
Range on HMM: 1-513/513
Sequence Identity: 22% (117 aa)

IRIIAKLGEGSFAEVYKVKNPKTQ--------------QVFAIKRLKKRYRTIEEV----------NKLPEVQYLKALQ----------------GHPNI
  || |.|||....||| .. .|.              .. |||..|..  ....             | |...|| |.                 |.||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

IKLYEVIYNSQ---------------DGYVALLFELMDVNLYEFVRDNQK--------PCDEKT------------TLLLI------YQLLKALD--YMH
.|||...| ..               . .. | ||.|| .||.. ..||.        | .|                 ..      ||.|..|.  |.|
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

EKN--LFHRDVKPENCMVNKATLE-------------------LKLCDFGSTRAVSN----------------------SGPYTEYVSTRWYRAPECILT
 ..   .||| |||| ..|. .                     ||.||||. |....                      . |||.||.|||||||| .| 
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

S---------GSYGREVDIWAVGCMLYELLTT--------RPLFP-----------GKHEIDQISRIHNIVGTPSIALLNQ------FRKNPN-------
.         . |. ..|.|.|||...|..|         .||||           ||..|||. .| .. |||.  ....      | |...       
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIK

---------------------------TQISFSFPQRTPQDLHKIIPM-----------------------------------ASPETVDLMGKMLIYNP
                            |. ..||.. |.......|                                    ..|. .||. |||.|.|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

ADRITAHDALLHPAF
..|||| .|| || |
DKRITAEQALQHPYF
Kinase 82181.m00150.AA S_TKc 5-290 28 2.7e-89 303.86 SMART 1-231 (231) Show / Hide 
Range on Protein: 5-290
Range on HMM: 1-231/231
Sequence Identity: 28% (86 aa)

IRIIAKLGEGSFAEVYKVKNPKTQQVFAIKRLKKRYRTIEEVNKLPEVQYLKALQGHPNIIKLYEVIYNSQDGYVALLFELMDV---NLYEFVRDNQKP-
 .|. |.|.|.|..|||... ||....|||..|         . . |.| ||   .||||.|||.|...   ... . .|..|    .|... ...... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----CDEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVSNSGPYTEYVSTRWYRAPECILTSGSYGR-EVDIWAVGCML
     .| ..  ..||...||.|.|...  |||.|||| ....   ..|.||||. | .      | .. |.||.||| .    .||. ..|.|..||.|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

YELLTTRPLFPGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGKMLIYNPADRITAHDALL-------HP
||.|. .|.||      |. .. ...|                                     |||  |.. |.| ..|..|.|| .||        ||
YEMLCGYPPFP------QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHP

AF
 |
WF
Kinase 82181.m00150.AA Pkinase 5-290 28 2.1e-87 301.45 Pfam 1-293 (293) Show / Hide 
Range on Protein: 5-290
Range on HMM: 1-293/293
Sequence Identity: 28% (89 aa)

IRIIAKLGEGSFAEVYKVKNPKTQQVFAIKRLKKRYRTIEE-VNKLP--EVQYLKALQGHPNIIKLYEVIYNSQDGYVALLFELMDV-----NLYEFVR-
..|. |.|.|||..||| .. .|....|.|..||| .  .. ....   |.|..| | .||||..||.. ..  .... . .|...       |..... 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST

DNQKPC--DEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLEL----KLCDFGSTRA--VSNSGPYTEYVSTRWYRAPECILTSGSYGREVD
.....   .|..    .||.|..|.|.|...  |||.||||....  . ..    |.||||. .     |.. .| .. |.||.||| |...  ||..||
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

IWAVGCMLYELLTTRPLFPGK----HEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGKMLIYNPADRITAHD
.|..||.|||.|. ||.|||.    . .||. .| .| |.|      . . ...    .  . .  . . .  . .|.|  |.. ..| ..|..|.||..
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQ

ALLHPAF
.| || |
ILQHPWF
Kinase 82181.m00150.AA CDK 6-290 31 8.6e-87 277.7 In-house 2-284 (284) Show / Hide 
Range on Protein: 6-290
Range on HMM: 2-284/284
Sequence Identity: 31% (101 aa)

RIIAKLGEGSFAEVYKVKNPKTQ-----QVFAIKRLKKRYR-TIEEVNKLP-----EVQYLKALQGHPNIIKLYEVIYNSQ---------DGYVALLFEL
 ...|.|||....||| .. .|.     |. |.|...     . ||   .|     |. .|| |  ||||.||..|.. ..         .  . . || 
EKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

MDVNLYEFVRDNQKPCDEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATL----ELKLCDFGSTRAVS-------NSGPYTEYVSTRWYRAPE
||  |... .             ...|||..|.|.|...  ||| || | ..|.        ||. |||  || .       .. .||  | |.||||||
MDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPE

CILTSGSYG--REVDIWAVGCMLYELLT---TRPLFPGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGK
  | |  |.   ..|.|.||| ..|..|    .|||||. ||||. .| .| |||.      . | |.                           ||. |
LLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------DLLNK

MLIYNPADRITAHDALLHPAF
|| |.|. ||.| .|| || |
MLCYDPKKRISAEQALQHPYF
Kinase 82181.m00150.AA CDC2 8-290 34 8.1e-81 248.01 In-house 4-301 (301) Show / Hide 
Range on Protein: 8-290
Range on HMM: 4-301/301
Sequence Identity: 34% (105 aa)

IAKLGEGSFAEVYKVKNPKTQQVFAIKRLKKRYRTIEE---VNKLPEVQYLKALQGHPNIIKLYEVIYNSQDGYVALLFELMDVNLYEFVR-DNQ--KPC
| |.|||.. .||| |. .|.|. |.|. .  . . ..      . |  .||.|. ||||.|| .||..     . . || .| .| .. .  ..  |. 
IEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKNKHM

DEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVS-NSGPYT--EYVSTRWYRAPECILTSGSYGREVDIWAVGCMLYEL
.. .   ..||.|..... | .  .||| || |  ..|.   .|. |||  ||.. .. .||    | |.||||||  | .  |  .||.|..|| ..|.
PPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---LTTRPLFPGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPM---------ASPETVDLMGKMLIYNPADRITAHDALL
    | .|||.|. ||||. .|  |.|||.   ..   ..|  .   .||. .|||| ||.|.         . || .||  .||.|.|..||.| .|| 
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKN--TFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

HPAF
|| |
HPYF
Kinase 82181.m00150.AA MAK 6-224 37 2.6e-79 252.07 In-house 2-267 (352) Show / Hide 
Range on Protein: 6-224
Range on HMM: 2-267/352
Sequence Identity: 37% (100 aa)

RIIAKLGEGSFAEVYKVKN------------------------------PKTQQVFAIKRLKKRYRTIEEVNKLPEVQYLKALQGHPNIIKLYEVIYNSQ
 .| .|| |.. .| . |                                .|. . |||| || . . ||  .| ||  ||.|. ||||.|| ||| .| 
QMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDSE

DGYVALLFELMDVNLYEFVRDNQK-PCDEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKA----------------TLELKLCDFGSTRAVSNS
.    . || |  |||. . | ..    | .    .|| | .| .||. . |||| |||| |..                     .|. |||  | . . 
NDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRSK

GPYTEYVSTRWYRAPECILTSGSYGREVDIWAVGCMLYELLTTRPLFPGKHEIDQISRIHNIVGTP
 ||| |||||||||||  | |..|.  .|.|||||   || | ||||||  |||||  |  . |||
PPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTP
Kinase 82181.m00150.AA CDKL 7-290 35 5.9e-72 245.3 In-house 3-286 (286) Show / Hide 
Range on Protein: 7-290
Range on HMM: 3-286/286
Sequence Identity: 35% (102 aa)

IIAKLGEGSFAEVYKVKNPKTQQVFAIKRLKK-RYRTIEEVNKLPEVQYLKALQGHPNIIKLYEVIYNSQDGYVALLFELMDVNLYEFVRDNQKPCDEKT
...|.||||   |.| .|  |.|. |||. |  ..  ..  . . |.  || |  |.||  | ||    . .   | || .| .. .    ... .||. 
KLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLK-HENIVNLIEVFR--RKRKLHLVFEYCDHTVLHELEEYPNGVDEHV

TLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVSNSG-PYTEYVSTRWYRAPECILTSGSYGREVDIWAVGCMLYELLTTRPL
.   ..|.|||... |  |  |||.||||  .. .  ..||||||  |  ...|  ||.|| ||||||||  .   .|| .|||||.||.. |...  ||
VRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFARMLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPL

FPGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQ-RTPQDLHKIIPMAS-PETVDLMGKMLIYNPADRITAHDALLHPAF
.||. .|||  .|   .|.      . |.|||   .  .||.  ... | |  | .| ... |.| |.|  .|..|.|. ... || |
WPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNP-FFHGMKFPEIEHMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase 82181.m00150.AA ERK7 6-290 32 1.7e-70 240.3 In-house 2-292 (292) Show / Hide 
Range on Protein: 6-290
Range on HMM: 2-292/292
Sequence Identity: 32% (96 aa)

RIIAKLGEGSFAEVYKVKNPKTQQVFAIKRLKKRYR-TIEEVNKLPEVQYLKALQGHPNIIKLYEVIYNSQDGYVALLFELMDVNLYEFVRDNQKPCDEK
 |. .|| | .  | |.   .|.|| |.|.    .|  .       |. .|.....|||||.|..||  . |  . | || |.  |   .|   .   . 
EIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRADNDRDIYLVFEFMETDLHAVIR-KGNILKDI

TTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVSNSG-------PYTEYVSTRWYRAPECILTSGSYGREVDIWAVGCMLYE
     .||||.|. |||  |. |||.|| | ... .   .|.||||  | ...           |||| ||||||||  | |  | . || | .|| | |
HKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLD-SECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILGE

LLTTRPLFPGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGKMLIYNPADRITAHDALLHPAF
.|. .|.|||   ..|| .| .... |. . ..    .   ..  . .|. .. |....|..... .||. ..|..||  |.|| .|| ||  
MLRGKPMFPGTSTMNQIEKILETIPKPTQEDIEAIGSHYAWNMLEQMNQQKRKTLDQMMPQCCDDAIDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase 82181.m00150.AA MAPK 55-290 33 1.9e-69 237.03 In-house 58-328 (328) Show / Hide 
Range on Protein: 55-290
Range on HMM: 58-328/328
Sequence Identity: 33% (92 aa)

LKALQGHPNIIKLYEVIYNS-----QD----GYVALLFELMDVNLYEFVRDNQKPCDEKTTLLLIYQLLKA--LDYMHEKNLFHRDVKPENCMVNKATLE
|. . .|.|||||..... .      .      . . .|||. .|.   . .| | ...    ..||.|..  | |.|  |  ||| ||.|  ||.   .
LRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNE-NCD

LKLCDFGSTRAVSNSGPY---------------TEYVSTRWYRAPECILT--SGSYGREVDIWAVGCMLYELLT-TRPLFPGKHEIDQISRIHNIVGTPS
||.||||  | . ..  .               ||||.|||||||| .|   .  |   ||.|.||| . |.||  .||||||. |||. .| ...||||
LKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPS

IALLNQFR--KNPNTQISFS--FPQRTPQDLHKIIPM----ASPETVDLMGKMLIYNPADRITAHDALLHPAF
  ....    ... . |.    .|........|..|     |.|. .||. |||  .| .|||. .|| || |
EEFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 82181.m00150.AA p38 5-290 34 1.2e-62 212.87 In-house 1-289 (289) Show / Hide 
Range on Protein: 5-290
Range on HMM: 1-289/289
Sequence Identity: 34% (101 aa)

IRIIAKLGEGSFAEVYKVKNPKTQQV---FAIKRLKKRYRTIEEVNKL-PEVQYLKALQGHPNIIKLYEVIYN-----SQDGYVALLFELMDVNLYEFVR
 . .  .|.|.. .| |.   .|.|    .|||.| . . ...       |.  || .. | |.|.| .|        ..   | .  ..|.  |.  ..
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMR-HENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

DNQKPCDEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVSNSGPYTEYVSTRWYRAPECILTSGSYGREVDIWAVGCML
  |.  |..   .|.||.|..| | |  .  ||| || |  ||    ||.  |||  |.  ..   |.|| |||||||| .|  . |   |||| ||| .
-CQRLSDDHIQ-FLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDC-ELRILDFGLARHCDDE--MTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIM

YELLTTRPLFPGKHEIDQISRIHNIVGTPSIALLNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGKMLIYNPADRITAHDALLHPAF
 ||.| |.||||.  |||. || ...|||.  ...   .        | ||.. .|.|.. ..|.|  .||. |||.  |  |||| .|. || |
AELITGRTLFPGDDHIDQLQRIMKVCGTPDEEFWQKIQSEEARNYIQSYPQMPRRDFHHVFMGANPQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase 82181.m00150.AA Pkinase_Tyr 5-200 29 2e-16 56.23 Pfam 1-209 (270) Show / Hide 
Range on Protein: 5-200
Range on HMM: 1-209/270
Sequence Identity: 29% (64 aa)

IRIIAKLGEGSFAEVYKVKNP----KTQQVFAIKRLKKRYRTIE--EVNKLPEVQYLKALQGHPNIIKLYEVIYNSQDGY--VALLFELMDV-NLYEFVR
|... |||||.| |||| .      .|..  |.| ||  .   .      . |.. .| |  ||||..|| |.. .|..   . . .|.|   .|... |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT-DQGEPNQIYIVMEYMPHGDLLDYLR

DN---QKPCDEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVSNSGPYTEYVST-------RWYRAPECILTSGSYGRE
..   ..| . |. |   .|  |...| ..||. |||.   ||.|.. ..  | |||| .|..  .  |  |...       .|. ||||| ..  .  .
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE-NNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWM-APECINYGK-FTTK

VDIWAVGCMLYELLT
 |.|. |  ..|..|
SDVWSFGVLMWEIFT
Kinase 82181.m00150.AA TyrKc 5-290 23 1.1e-14 15.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 5-290
Range on HMM: 1-280/280
Sequence Identity: 23% (75 aa)

IRIIAKLGEGSFAEVYKVKNPKTQQVFAIKRLKKRYRTIEEVNKLPEVQYLKAL-QGHPNIIKLYEVIYNS-----QDGYVALLFELMDV-NLYEFVRDN
|. . ||||| | |||| .    .|| |.| ||.    .|.   . | . .. |   ||||..|| |.  .      .. . ...|.|.  .| .. |..
ITLGKKLGEGAFGEVYKGTWK--IQV-AVKMLKEDA--REDF--MREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

QKPCDEKTTLLLIYQLLKALDYMHEKNLFHRDVKPENCMVNKATLELKLCDFGSTRAVSNS------GPYT-------EY--VSTRWYRAPECILTSGSY
..    |. |   .|  .  .| |.||. |||    ||.|..     | .||| .|.. .       . |        .   .  ||. |||||   | .
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGKF

GREVDIWAVGCMLYELLTT-RPLFPG-----KHEIDQISRIHNIVGTPSIAL----LNQFRKNPNTQISFSFPQRTPQDLHKIIPMASPETVDLMGKMLI
  . |.|. | ...|..|   .  ||     .  .. | .. .    |  .                                 . ...|  ..| .   
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------------------------F-VCCPDEMYQIMKQCWH

YNPADRITAHDALLHPAF
..|.|| |  .   |  |
EDPEDRPTFSEI--HECF
Kinase 82181.m00150.AA MAK 239-290 33 1.5e-13 39.08 In-house 297-352 (352) Show / Hide 
Range on Protein: 239-290
Range on HMM: 297-352/352
Sequence Identity: 33% (19 aa)

QISFSFPQRTP---QDLHKIIPMASP-ETVDLMGKMLIYNPADRITAHDALLHPAF
.. | |||  |     | ..|| .|. . ..|| .|| ..|  | || ... .| |
MMNFRFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase 82181.m00150.AA MAPK 5-38 17 0.001683 7.71 In-house 1-40 (328) Show / Hide 
Range on Protein: 5-38
Range on HMM: 1-40/328
Sequence Identity: 17% (7 aa)

IRIIAKLGEGSFAEVYKVKNPK------TQQVFAIKRLKK
 .|. ..|.|..  | ...  .      ...  |||.. .
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISR