Gene 92204.m00063 (T.vaginalis)
92204.m00063
Species: T.vaginalis
Alias: TvagK0972, 92204.m00063
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 92204.m00063.AA | Protein | None | 216 | None | Fasta, JSON |
| 92204.m00063.kin_dom | Protein Kinase Domain | None | 204 | None | Fasta, JSON |
Protein domains of 92204.m00063.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 92204.m00063.AA | Bud32 | 42-214 | 34 | 1.3e-53 | 169.6 | In-house | 67-269 (269) | Show / Hide |
Range on Protein: 42-214 Range on HMM: 67-269/269 Sequence Identity: 34% (71 aa) LDKMLRSDRIKSEARTNFRCMQLGVPTCPIVYIDPETSTLIMEEL---NG----GSLKQMIF--NCT---DHNDPKVIQALKEMGQIIATLHNNEILHGD || | . |.| |.| || .| . . .|... ..||.. | .|. | . | | | .. .|..|..|. .|.| |.||| LDQQLTKHRTKQEVRAMNRCRKAGICVPYVYFCDNYNHCIYMEYIEESPGGHGFYTVKNYIWQHQETQKEDQHDQCLREFCKKVGRQIGKMHWNHIIHGD LTTSNFMLH----DGK-----VRVIDFGLSFQSGLP-EDFAVDLYVMERAFNSSHPDKTD-----LLKIIFDSYT---EHCKKAPVILKRLKKVRSRGRK ||||| || | . . ||||||..| .. || .||||| |||| | || .. . .| |||. ||.. || |||| LTTSNMMLRHPYADWTKLYGQMHLIDFGLSYISNSVPEDKGVDLYVLERAFLSTHPKCEQKYNAWIFEHFMENYRKQDTKCKKFKAVLKKFNEVRLRGRK RSM |.| RTM |
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| Kinase | 92204.m00063.AA | Ciliate-E2 | 81-150 | 23 | 4.2e-13 | 41.32 | In-house | 111-203 (365) | Show / Hide |
Range on Protein: 81-150 Range on HMM: 111-203/365 Sequence Identity: 23% (23 aa) LIMEELNGGSLKQ-MIFNCT--------DHNDPKVIQALKEMGQII------------------ATLHNNE-ILHGDLTTSNFMLHDGKVRVIDFGLS |.|| ..||.|.. .. |.. | . .. .... | ||. ||.. |.| |. .| .. . .|||||| LVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----IKIIDFGLS |
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| Kinase | 92204.m00063.AA | Ciliate-E2-Unclassified | 81-150 | 21 | 4.8e-10 | 31.06 | In-house | 98-194 (352) | Show / Hide |
Range on Protein: 81-150 Range on HMM: 98-194/352 Sequence Identity: 21% (21 aa) LIMEELNGGSLKQMIFNCTD----------------HNDPKVIQ---ALKEMGQIIATL---HNNE-ILHGDLTTSNFMLHDG----KVRVIDFGLS ..|| ..||.|.|.| .. . . . .. |.. . ||. | | . |.| |.. .| ..... ....||||.| IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGIS |
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| Kinase | 92204.m00063.AA | TKL-Unique | 119-150 | 37 | 4.1e-08 | 24.9 | In-house | 125-164 (290) | Show / Hide |
Range on Protein: 119-150 Range on HMM: 125-164/290 Sequence Identity: 37% (15 aa) TLHNNE--ILHGDLTTSNFMLHDG------KVRVIDFGLS .||..| |.|.||..||| . . .....||||| YLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLS |
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| Kinase | 92204.m00063.AA | Dicty3 | 116-152 | 21 | 2.8e-07 | 19.89 | In-house | 123-187 (351) | Show / Hide |
Range on Protein: 116-152 Range on HMM: 123-187/351 Sequence Identity: 21% (14 aa) IIATLHNNE-ILHGDLTTSNFMLHDGK---------------------------VRVIDFGLSFQ ... .|.|. |.|.|... | || . . . .||||||.. TLNYIHKNCHIIHRDIKCDNIMLDNDEQHQCNNNNNKMSSTCRDIQCYYSNEINWKLIDFGLSKN |
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| S_TKc | 92204.m00063.AA | S_TKc | 3-215 | 13 | 3e-06 | -85.41 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 3-215
Range on HMM: 1-231/231
Sequence Identity: 13% (36 aa)
RENWVEIKRGAEASIWKMQLFG--KNCVAKVLEPKTWRAAPLDKMLRSDRIKSEARTNFRCMQLGVPTCPIVYIDPETSTLIMEELNG--GSLKQMIFNC
| .| .|| .. .| . . . . |.. ..|..| . . . .. |. | . ..|| ..| |.|...| ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR
TD------HNDPKVIQALKEMGQIIATLHNNEILHGDLTTSNFMLHDGKVRVIDFGLS-----------------FQSGLPEDF-AVD----------LY
. . .... . .. .|.. |.| || .| .| . . ..||||. . . .. ..| ..
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQLTTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML
VMERAFNSSHPDKTDLLKIIFDSYTEHCKKAPVILKRLKKVRS-----RGRK-------RSMV
. . | . ..|.| . | | | |.| . . .
CGYPPFP----QMQMMFKKIG----SPEAKD-FIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
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| Kinase | 92204.m00063.AA | TKL | 117-150 | 21 | 3e-06 | 18.29 | In-house | 145-201 (364) | Show / Hide |
Range on Protein: 117-150 Range on HMM: 145-201/364 Sequence Identity: 21% (12 aa) IATLHNNE--------ILHGDLTTSNFMLH-DGK--------------VRVIDFGLS .. ||... |.| ||...| ... ... . . ||||| MNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLS |
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| Kinase | 92204.m00063.AA | Ciliate-E8 | 120-150 | 44 | 7e-06 | 14.46 | In-house | 105-138 (138) | Show / Hide |
Range on Protein: 120-150 Range on HMM: 105-138/138 Sequence Identity: 44% (15 aa) LHNNEILHGDLTTSNFMLH---DGKVRVIDFGLS |||| | | |. | .. | |...|||| | LHNNNIIHCDFKLNNILVQRNDDTKIKIIDFGFS |
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| Kinase | 92204.m00063.AA | RAF | 105-149 | 34 | 1.1e-05 | 14.13 | In-house | 104-149 (282) | Show / Hide |
Range on Protein: 105-149 Range on HMM: 104-149/282 Sequence Identity: 34% (16 aa) KVIQALKEMGQIIATLHNNEILHGDLTTSNFMLHDG-KVRVIDFGL ..|. .. . | || .|.| || . | .||.. .|.. |||| WLIDISRQVCQGMDYLHAKNIIHRDLKSNNIFLHEDMTVKIGDFGL |
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| Kinase | 92204.m00063.AA | Ciliate-E2b | 120-150 | 34 | 1.1e-05 | 13.38 | In-house | 118-149 (272) | Show / Hide |
Range on Protein: 120-150 Range on HMM: 118-149/272 Sequence Identity: 34% (11 aa) LHNNEILHGDLTTSNFMLHD-GKVRVIDFGLS |||..|...|. .| |.. | .. ||.|.. LHNQNIIYRDIKPENIMVDHKGYMKLIDMGTA |
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| Kinase | 92204.m00063.AA | Ciliate-A1 | 117-150 | 40 | 1.4e-05 | 14.85 | In-house | 114-148 (301) | Show / Hide |
Range on Protein: 117-150 Range on HMM: 114-148/301 Sequence Identity: 40% (14 aa) IATLHNNEILHGDLTTSNFMLH-DGKVRVIDFGLS .| .| ||| || | ..| | | ..|.|.| YADIHDHNILHRDLKPQNILIHFDDKWKICDLGMS |
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