Gene 83629.m00130 (T.vaginalis)

83629.m00130

Species: T.vaginalis
Alias: TvagK0779, 83629.m00130
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
83629.m00130.AA Protein None 315 None Fasta, JSON
83629.m00130.kin_dom Protein Kinase Domain None 123 None Fasta, JSON

Protein domain

Protein domains of 83629.m00130.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83629.m00130.AA CAMK 48-124 19 6.8e-20 60.14 In-house 202-336 (425) Show / Hide 
Range on Protein: 48-124
Range on HMM: 202-336/425
Sequence Identity: 19% (26 aa)

HRDLKPDNIVVDGDM-----------------IPHIIDWDDSTDRFSLS-------------------------ISERHGTIPFAA-PEIFSAQ------
||||||.|| .| ..                    |||.  ..  .. .                          ... || ...| ||... .      
HRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQ

---------RRCESDIFSFGAIMFNMITGRYPFYS
            ..|. | | |.. | .|..|||.
NATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYG
Kinase 83629.m00130.AA Ciliate-E2-Unclassified 1-124 23 5.1e-18 59.12 In-house 100-272 (352) Show / Hide 
Range on Protein: 1-124
Range on HMM: 100-272/352
Sequence Identity: 23% (41 aa)

MDYIPGITITKLIS--------GGCVGNRIKKLCML-----------EIFAAIASQL-TLMKEMEIKHRDLKPDNIVVDGDM---IPHIIDWDDST----
|.|..| .  . |.        |.  ....|. ...            .|| | . |  | ..  | |||.||.||..| ..    . |||.  |     
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------DRFSLSISERH----GTIPFA----APEIFSAQRRCE-----SDIFSFGAIMFNMITGRYPFYS
          ...  ....     ||. .     |||..  |   .     .||.|.| |.. |..|.||||.
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYD
Kinase 83629.m00130.AA Ciliate-E2 48-122 22 8.4e-17 54.19 In-house 184-296 (365) Show / Hide 
Range on Protein: 48-122
Range on HMM: 184-296/365
Sequence Identity: 22% (27 aa)

HRDLKPDNIVVDGDMIPHIIDWDDSTDRFSLSISERH---------------------------------GTIPFAAPEIFSAQRR----------CESD
|||.||.||..     . |||.  |..    .. ..|                                 || .. ||||.. .             ..|
HRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCD

IFSFGAIMFNMITGRYPF
|.|.| |.. |..|..||
IWSLGVILYEMLFGKPPF
Kinase 83629.m00130.AA Pkinase 48-125 28 8.5e-13 46.33 Pfam 131-215 (293) Show / Hide 
Range on Protein: 48-125
Range on HMM: 131-215/293
Sequence Identity: 28% (25 aa)

HRDLKPDNIVVDGDMIP----HIIDWDDST---DRFSLSISERHGTIPFAAPEI--FSAQRRCESDIFSFGAIMFNMITGRYPFYSA
||||||.|| .| .. .    .|.|.  .       .   . . ||....|||.  ..     ..|..|.| |.. |..|| ||...
HRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH
Kinase 83629.m00130.AA TKL 48-232 13 2.5e-10 33.4 In-house 163-364 (364) Show / Hide 
Range on Protein: 48-232
Range on HMM: 163-364/364
Sequence Identity: 13% (34 aa)

HRDLKPDNIVVDGDMI--------------PHIIDWDDSTDRF---SLSISE------------------RHGTIPFAAPEIFSAQRR------------
|||||..|| || ..               . | |   |.. .   . . ..                  . ||. . |||..  |              
HRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCK

-----CESDIFSFGAIMFNMITGRYPFY-SAYRTRAGL-------QSLADKFSELQLPNLAETLDVLAEFEQMDDSEQYNHWPTVVSYVEPILTELIKAG
       .|..||| ... ..|.. |.|   |... .           .||.  . .|.  ..                                     
GFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQN-------------------------------------

ARDDYIYNERFQNDPFNRKISELIELCCKQEPDGRITPEDLHDRI
    .      ..... . ...|.. |....|. | . ... .|.
---HH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 83629.m00130.AA CAMKL 85-122 38 2.3e-09 25.87 In-house 195-236 (297) Show / Hide 
Range on Protein: 85-122
Range on HMM: 195-236/297
Sequence Identity: 38% (16 aa)

GTIPFAAPEIFSA--QRRC--ESDIFSFGAIMFNMITGRYPF
|. |..|||||.   .. .  . || | | |...|..|..||
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF
Kinase 83629.m00130.AA AGC 85-124 36 1.8e-08 16.48 In-house 267-307 (395) Show / Hide 
Range on Protein: 85-124
Range on HMM: 267-307/395
Sequence Identity: 36% (16 aa)

G--TIPFAAPEIFSAQRRCESDIFS--FGAIMFNMITGRYPFYS
|  |  . ||||.      . |. |  .|..|. |.||. |||.
GPCTPEYMAPEIL---YGKACDWWSFGLGCLMYEMLTGYPPFYG
Kinase 83629.m00130.AA S_TKc 3-233 13 2.7e-08 -55.29 SMART 1-231 (231) Show / Hide 
Range on Protein: 3-233
Range on HMM: 1-231/231
Sequence Identity: 13% (42 aa)

YIPGITI-------------TK---------------------------------------------LISG--GCVGNRIKKLCM-----------LEIF
|  . .|             .|                                             ...|  | .  .|||                ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYM

AAIASQLTLMKEMEIKHRDLKPDNIVVDGDMIPHIIDWDDSTDRFSLSISERHGTIPFAAPEIFSAQRRC-ESDIFSFGAIMFNMITGRYPFYSAYRTRA
. |.. |  . .. | ||||||.|| .|      |.|   ..       .   ||  . |||..  .  . ..|. |.| |.. |..|. ||.       
YQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP-------

GLQSLADKFSELQLPNLAETLDVLAEFEQMDDSEQYNHWPTVVSYVEPILTELIKAGARDDYIYNERFQNDPFNRKISELIELCCKQEPDGRITPEDLH-
               .........                                                  .   ..|. |.. .|. |.| | |. 
---------------QMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQD

------DRIY
      .   
EWDIKCHPWF
Kinase 83629.m00130.AA RSK 85-124 33 1.1e-07 24.59 In-house 170-214 (278) Show / Hide 
Range on Protein: 85-124
Range on HMM: 170-214/278
Sequence Identity: 33% (15 aa)

GTIPFAAPEIFS-AQRRC----ESDIFSFGAIMFNMITGRYPFYS
.|| ..|||.   |....      |..|.|..|. | ||. ||..
YTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQG
Kinase 83629.m00130.AA MARK 85-122 40 3.7e-07 19.65 In-house 167-206 (262) Show / Hide 
Range on Protein: 85-122
Range on HMM: 167-206/262
Sequence Identity: 40% (16 aa)

GTIPFAAPEIFSAQRRC--ESDIFSFGAIMFNMITGRYPF
|| |..|||||. .. .  . || | | ... |..|..||
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPF
Kinase 83629.m00130.AA CAMK-Tt 85-122 42 6.6e-07 19.32 In-house 299-338 (396) Show / Hide 
Range on Protein: 85-122
Range on HMM: 299-338/396
Sequence Identity: 42% (17 aa)

GTIPFAAPEIFSAQR-RCES-DIFSFGAIMFNMITGRYPF
||. | |||||. .    |. |. | |.|.. |  |. ||
GTVAFSAPEIFNEDCCYDETIDMWSAGCILYTMLCGQEPF
Kinase 83629.m00130.AA Ciliate-E9 40-59 45 5.6e-05 11.43 In-house 127-146 (298) Show / Hide 
Range on Protein: 40-59
Range on HMM: 127-146/298
Sequence Identity: 45% (9 aa)

LMKEMEIKHRDLKPDNIVVD
. ..  | ||||||.|...|
MHQYQNICHRDLKPENMLID
Kinase 83629.m00130.AA Ciliate-E9 104-124 52 0.000127 10.27 In-house 207-227 (298) Show / Hide 
Range on Protein: 104-124
Range on HMM: 207-227/298
Sequence Identity: 52% (11 aa)

DIFSFGAIMFNMITGRYPFYS
|||| | | | |... ||| .
DIFSAGCILFMMVMNQYPFFH
Kinase 83629.m00130.AA CAMKL 48-68 47 0.000253 9.54 In-house 150-172 (297) Show / Hide 
Range on Protein: 48-68
Range on HMM: 150-172/297
Sequence Identity: 47% (11 aa)

HRDLKPDNIVVDGDM--IPHIID
|||.||.|| .| ..     |||
HRDIKPENILLDENGNNNIKIID
Kinase 83629.m00130.AA AGC 48-68 50 0.000263 5.46 In-house 177-198 (395) Show / Hide 
Range on Protein: 48-68
Range on HMM: 177-198/395
Sequence Identity: 50% (11 aa)

HRD-LKPDNIVVDGDMIPHIID
||| |||.||. | |   .. |
HRDYLKPENILLDEDGHIKLTD
Kinase 83629.m00130.AA MARK 48-62 53 0.000423 9.49 In-house 127-141 (262) Show / Hide 
Range on Protein: 48-62
Range on HMM: 127-141/262
Sequence Identity: 53% (8 aa)

HRDLKPDNIVVDGDM
|||.||.|| .| ..
HRDIKPENILIDENG
Kinase 83629.m00130.AA CAMK-Tt 30-61 43 0.004656 5.75 In-house 229-260 (396) Show / Hide 
Range on Protein: 30-61
Range on HMM: 229-260/396
Sequence Identity: 43% (14 aa)

IFAAIASQLTLMKEMEIKHRDLKPDNIVVDGD
||  | .    | |  . |||||| ||  . |
IFKQILDAIKYMHENYVCHRDLKPNNILCNED
Kinase 83629.m00130.AA RSK 48-57 80 0.015411 5.54 In-house 127-136 (278) Show / Hide 
Range on Protein: 48-57
Range on HMM: 127-136/278
Sequence Identity: 80% (8 aa)

HRDLKPDNIV
||||||.||.
HRDLKPENIL