Gene 96017.m00044 (T.vaginalis)
96017.m00044
Species: T.vaginalis
Alias: TvagK0510, 96017.m00044
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 96017.m00044.AA | Protein | None | 379 | None | Fasta, JSON |
| 96017.m00044.kin_dom | Protein Kinase Domain | None | 124 | None | Fasta, JSON |
Protein domains of 96017.m00044.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 96017.m00044.AA | CK1 | 4-174 | 60 | 4.3e-116 | 392.0 | In-house | 99-271 (271) | Show / Hide |
Range on Protein: 4-174 Range on HMM: 99-271/271 Sequence Identity: 60% (104 aa) NQQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIGT-GKKSNLIYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHLGIEQSRRDD |...|||||| ||| |. |.|.|...||||||||.|||.|. ||... .|.|||||.|.|||.||..||||| .| |.|| || ||||||||||||||| NRKFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD LESLGYVLVYLLKGQLPWQGIQSENLKQKYEKIGEKKMTTSFDMLCQD-LPEEFIKYFEIVRALDFAQEPPYS .|||||||.|.|.|.|||||.. .. |||||||.||||.|. ..||.. .|.||. |....| |.|...| | MESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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| Kinase | 96017.m00044.AA | CK1-Unclassified | 4-148 | 64 | 3.3e-114 | 338.44 | In-house | 98-244 (244) | Show / Hide |
Range on Protein: 4-148 Range on HMM: 98-244/244 Sequence Identity: 64% (95 aa) NQQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIG-TGKKSNLIYLIDFGLSKKYRDP-KTKEHIPYRGDKELVGTSRYVSINTHLGIEQSRRD |...|||||| ||| | |.|.|...||||||||.|||.| .||... .|.|||||||.|.|. ||..||||| .| |.|| || |||.|||||||||| NRKFSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRD DLESLGYVLVYLLKGQLPWQGIQSENLKQKYEKIGEKKMTTSFDMLC |||||||||.|.|||.||||.|. .| |.||||| |.||.|. ..|| DLESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC |
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| Kinase | 96017.m00044.AA | CK1-D | 6-176 | 60 | 6.5e-92 | 311.66 | In-house | 91-261 (261) | Show / Hide |
Range on Protein: 6-176 Range on HMM: 91-261/261 Sequence Identity: 60% (104 aa) QLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIGTGKKSNLIYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHLGIEQSRRDDLES . ||||||. ||| || |.|.| | ||||||||.|||.| ||. |..|.|||||.|.|||..|..||||| .|.| || || |||||.|||||||||||| KFSLKTVLMLADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLES LGYVLVYLLKGQLPWQGIQSENLKQKYEKIGEKKMTTSFDMLCQDLPEEFIKYFEIVRALDFAQEPPYSQL |||||.| .| |||||.. . .||||.| |||| |. | ||. .|.|| .|.. .| | | . | |. | LGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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| Kinase | 96017.m00044.AA | CK1-G | 4-176 | 51 | 6.1e-89 | 301.6 | In-house | 90-266 (266) | Show / Hide |
Range on Protein: 4-176 Range on HMM: 90-266/266 Sequence Identity: 51% (91 aa) NQQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIG--TGKKSNLIYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHLGIEQSRRD . . |.|||.. | | | ...|.|..| | ||.||.||||| |. ..|..||||. |.|.||.|| ||||| | | || || ||||||| |||||| DRKFSVKTVCMVAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRD DLESLGYVLVYLLKGQLPWQGIQSENLKQKYEKIGEKKMTTSFDMLCQD--LPEEFIKYFEIVRALDFAQEPPYSQL |.|.|| . | | |.||||| .|.|..|.|||..| | . ||| .||.| .| ..|| ||| .| | | DMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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| Kinase | 96017.m00044.AA | CK1-A | 4-176 | 57 | 5.9e-87 | 295.18 | In-house | 89-261 (261) | Show / Hide |
Range on Protein: 4-176 Range on HMM: 89-261/261 Sequence Identity: 57% (100 aa) NQQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIGTGKKSNLIYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHLGIEQSRRDDL . . ..||||. ||| | | |.||. ||||||||.|||.|.|. | ..||||||.|||||..|..||||| ||.|.|| || ||| |||||||||||. KRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDM ESLGYVLVYLLKGQLPWQGIQSENLKQKYEKIGEKKMTTSFDMLCQDLPEEFIKYFEIVRALDFAQEPPYSQL ||.|||..| .|.|||||.. . ||||||| ||||.|. ..||. | || |.. .|.| | ..| | | ESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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| Kinase | 96017.m00044.AA | CK1 | 4-176 | 40 | 7.3e-84 | 284.91 | In-house | 126-339 (339) | Show / Hide |
Range on Protein: 4-176 Range on HMM: 126-339/339 Sequence Identity: 40% (87 aa) NQQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIGT------GKKSN--------LIYLIDFGLSK-KYRDP-----------KTKEHIPYRG- |. .|.||.| |.| . ..|||...||||||||.||..| ||. . .|.||||... ||||. ||..|.|.| NRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREH --DKELVG-TSRYVSINTHLGIEQSRRDDLESLGYVLVYLLKGQ--LPWQGIQSENL-------KQKYEKIGEKKMTTSFDMLCQD-----LPEEFIKYF | ..| | ||.|||.|||.||.|||||.|..|.|...|||. ||||.. .|. |.|||.| |||| |.|. || .|.|| |.. KKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIM EIVRALDFAQEPPYSQL ...|.|.. .|.| . KYIRSLKYYDRPDYEMI |
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| Kinase | 96017.m00044.AA | TTBKL | 23-180 | 28 | 3.4e-46 | 153.98 | In-house | 115-288 (288) | Show / Hide |
Range on Protein: 23-180 Range on HMM: 115-288/288 Sequence Identity: 28% (52 aa) IQYMHERHFIHRDIKPENFLIGTGKK----SNLIYLIDFGLSKKYRDP----------KTKEHIPYRG---DKELVGTSRYVSINTHLGIEQSRRDDLES ...||. |||||.|| |. .| .. . ..||||||....|... ..... . | .. || ||.|.| |.. ||.| ||| | LKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWS LGYVLVYLLKGQLPWQGIQSENLKQKYEKIGEKKMTTSFDMLCQD------LPEEFIKYFEIVRALDFAQEPPYSQLRQIF . |....|..| |||... .. ..|...|. .. . |..| .| || | .. .|.|.....|.|. ....| WMYMIIELHCG-LPWTNMEDK------MEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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| Kinase | 96017.m00044.AA | Worm6 | 2-176 | 28 | 2.3e-36 | 127.13 | In-house | 96-279 (279) | Show / Hide |
Range on Protein: 2-176 Range on HMM: 96-279/279 Sequence Identity: 28% (53 aa) RHNQQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIGT-----GKKSNLIYLIDFGLSK--KYRDPKTKEHIPYR-GDKELVGTSRYVSINTHL | .. .|. | | | | . |. .| .|||||.|| || || ... ||..|||... ||.. ... . | | . . .|| || ... | RPDRKFSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTP-RWTACGFRGTVRYAPLACHK GIEQSRRDDLESLGYVLVYLLKGQLPWQGIQSENLKQ-KYEKIGEKKMTTSFDMLCQDLPE-EFIKYFEIVRALDFAQEPPYSQL |.||.|.||.|| |..| ...|.|||... .. .. .... .. . . |. . | || . .... ... .| | .. GQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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| Kinase | 96017.m00044.AA | TTBK | 5-176 | 36 | 1.6e-30 | 105.1 | In-house | 92-257 (257) | Show / Hide |
Range on Protein: 5-176 Range on HMM: 92-257/257 Sequence Identity: 36% (63 aa) QQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIG-TGKKSNLIYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHLGIEQSRRDDL . || | | | . |. |. | |||||| || .| . .. . .|..|||| .| . | | | || || ||| |. | |.||| GCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACG-EVRPPREVAGFRGTVRYASINAHRNREMGRHDDL ESLGYVLVYLLKGQLPWQGIQSENLKQKYEKIGEKKMTTSFDMLCQDLPEEFIKYFEIVRALDFAQEPPYSQL || |.|| ..||||| | | | ...|| | || ...|.|| . . .. |... | | . WSLFYMLVEFVQGQLPWRKI-----KDK-DQVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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| Kinase | 96017.m00044.AA | Pkinase | 23-139 | 24 | 5.3e-26 | 93.02 | Pfam | 121-234 (293) | Show / Hide |
Range on Protein: 23-139 Range on HMM: 121-234/293 Sequence Identity: 24% (31 aa) IQYMHERHFIHRDIKPENFLIGTGKKSNL---IYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHL-GIEQSRRDDLESLGYVLVYLLKGQL ..|.|.. .||||.||||.|| .. .. . ..||||.|... . ... . ..||..|.. .. | . ... | |.| .| ..| |.. LEYCHSMGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRP PWQGI----QSENLKQKYEKIGEKK |..| . .|....|.... PFPGHCWHDN-HDQMQMICRIMGPP |
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| Kinase | 96017.m00044.AA | Dual | 1-114 | 33 | 4.1e-21 | 67.62 | In-house | 102-217 (282) | Show / Hide |
Range on Protein: 1-114 Range on HMM: 102-217/282 Sequence Identity: 33% (39 aa) MR--HNQQLSLKTVLIFADQAICLIQYMHERHFIHRDIKPENFLIGTGKKSNLIYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHLGIEQS .| . ||| . . | | . ||. | ..||.||| || .| | . .|. ||.. .|| ||..|.| . | |. || .. . .| RRKYIMGQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHRTARKKVKMYGCGRYACRACMMQKDQG RRDDLESLGYVLVYLL | ||||. | . .|. RKDDLECWIYMVFDLM |
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| Kinase | 96017.m00044.AA | S_TKc | 1-190 | 12 | 5e-06 | -88.07 | SMART | 18-231 (231) | Show / Hide |
Range on Protein: 1-190 Range on HMM: 18-231/231 Sequence Identity: 12% (36 aa) MRHNQ------------------------------------------------Q--LSLKTVLI----------FADQAICLI--------QYMHERHFI ||. . .|.... | .. . .|.|....| CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGII HRDIKPENFLIGTGKKSNLIYLIDFGLSKKYRDPKTKEHIPYRGDKELVGTSRYVSINTHLGIEQSR-RDDLESLGYVLVYLLKGQLPWQGIQSENLKQK |||.|||| |. . | ..||||.... . ..|| |.. .. . | |.| .| .| |. |.. .... HRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMM YEKIGEKKMTTSFDMLCQDLPEEFIKYFEIVRALDFAQEPPYSQLRQIFRECFL------------K-------HDFV ..||| ...... | |. . | .. FKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF |
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