Gene TVAG_127400 (T.vaginalis)

TVAG_127400

Species: T.vaginalis
Alias: TVAG_127400, TvagK1048
External Links:
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
TVAG_127400.AA Protein None 298 None Fasta, JSON
TVAG_127400.kin_dom Protein Kinase Domain None 102 None Fasta, JSON

Protein domain

Protein domains of TVAG_127400.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc TVAG_127400.AA S_TKc 6-287 18 7.6e-09 -47.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 6-287
Range on HMM: 1-231/231
Sequence Identity: 18% (58 aa)

EILEPPIGGGFEGKVYLTKSGK-----VVKIMADVPENFKSAYRQFLLTDFFEKCYTNPPFAHIFELSTSNGKIKLKMEKYYK---DLSARMKT------
  .  .|| |  ||||. .  |      .||.       ....|   .     ..     .  .|.     ... . ||       ||  ..|       
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---ITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPELSKGWFDV-MNYVYSLGVIFLE
   ..  .| ..| ||....  . ..  .  |||| |||..    | ..|||.  .|         ||     |  ||.    ..     ..|.|.|. |
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYE

MLHHGKI--KEKSLEYIKQLQKGEEEKPASHESNDKSQSQSNNNNEETAYDEMLTETIEHFKKNPYAIEFNDISDEEKEFITFCIS-DFEGRYTFEEAQN
||  |.        . .|..                                                     |.| |.||  |   | | |.|  || .
MLC-GYPPFP-QMQMMFKKIG----------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

--------EFK
        .. 
DEWDIKCHPWF
Kinase TVAG_127400.AA GEK 108-141 47 3e-06 16.36 In-house 113-146 (269) Show / Hide 
Range on Protein: 108-141
Range on HMM: 113-146/269
Sequence Identity: 47% (16 aa)

ISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGS
|  .  |.||  |.|| |.|   .| | | ||||
IDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFGS
Kinase TVAG_127400.AA MEK5 104-188 33 4e-06 18.17 In-house 102-184 (254) Show / Hide 
Range on Protein: 104-188
Range on HMM: 102-184/254
Sequence Identity: 33% (29 aa)

IFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPE-LSKGWFDVMNYVYSLGVIFLEM
|  |.  | .|  .  | || |.| | .| | | |||    | .   .   |..    |  || .|   . .   |.|||. |.||
IVKGLNYLWNLKIMHRDVKPSNMLVNTQGQIKLCDFGVSTQLVNSITR---TYIGTNAYMAPERISGDQYGIHSDVWSLGIFFMEM
Kinase TVAG_127400.AA Ciliate-A2 77-140 30 5e-06 17.33 In-house 76-148 (272) Show / Hide 
Range on Protein: 77-140
Range on HMM: 76-148/272
Sequence Identity: 30% (22 aa)

KMEKY-YKDLSARMK-----T--ITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGS-IFLTDFG
.|||. ...|.   .     .  | .  ...|  || ..|  |   .||. ||...||| . ..  | | |||
QMEKCPECSLQDWIDKFQNQQKFIPDHQFVHFACQILDAIEYLHNKNYVLRDLSLRNILIDQDNQIIKLCDFG
Kinase TVAG_127400.AA PLK1 84-167 33 5e-06 15.43 In-house 88-170 (253) Show / Hide 
Range on Protein: 84-167
Range on HMM: 88-170/253
Sequence Identity: 33% (28 aa)

DLSARMKTITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPEL
.|  | |.||  ..  .| ||  |.  | ... .  ||| ||.  | |  . . |||   .. | || |. |      |  ||.
ELHKRRKAITEPECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKC-EYDGERKKTLCGTPNYIAPEV
Kinase TVAG_127400.AA AMPK 92-140 34 5e-06 13.83 In-house 97-145 (254) Show / Hide 
Range on Protein: 92-140
Range on HMM: 97-145/254
Sequence Identity: 34% (17 aa)

ITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFG
.. ..| .|. || ||.. . ..  |  |||| |.| ... .| . |||
LQEREACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFG
Kinase TVAG_127400.AA RSK-Unclassified 90-140 29 1.3e-05 13.07 In-house 96-146 (283) Show / Hide 
Range on Protein: 90-140
Range on HMM: 96-146/283
Sequence Identity: 29% (15 aa)

KTITRDDAYKFMDQIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFG
| .. ||.  ..  .      |  .. .. |||| ||.    | . ||||.
KCFCEDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFD
Kinase TVAG_127400.AA SGK 117-140 54 1.3e-05 12.83 In-house 147-170 (283) Show / Hide 
Range on Protein: 117-140
Range on HMM: 147-170/283
Sequence Identity: 54% (13 aa)

VFQDLKPGNILCNIHGSIFLTDFG
.. |||| |||    | . |||||
IYRDLKPENILLDHQGHCCLTDFG
Kinase TVAG_127400.AA Ciliate-E1 103-166 29 1.5e-05 14.53 In-house 117-180 (202) Show / Hide 
Range on Protein: 103-166
Range on HMM: 117-180/202
Sequence Identity: 29% (19 aa)

QIFSGISMLIDLEYVFQDLKPGNILCNIHGSIFLTDFGSGVFLTEIDGKRQFTFMTNKIYTDPE
|.. |...| ..   ..|.|| ||| |  |   ..||| . || . . . .  .   . |  ||
QLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPE
Kinase TVAG_127400.AA STE7-Unclassified 120-140 57 3.2e-05 14.46 In-house 145-165 (301) Show / Hide 
Range on Protein: 120-140
Range on HMM: 145-165/301
Sequence Identity: 57% (12 aa)

DLKPGNILCNIHGSIFLTDFG
|.||||||.|  | . ..|||
DIKPGNILVNSKGQVKICDFG
Kinase TVAG_127400.AA CDK7 120-140 52 4.4e-05 9.02 In-house 127-147 (288) Show / Hide 
Range on Protein: 120-140
Range on HMM: 127-147/288
Sequence Identity: 52% (11 aa)

DLKPGNILCNIHGSIFLTDFG
|||| | | |. | . ..|||
DLKPNNLLMNENGQLKIADFG