Gene 89692.m00436 (T.vaginalis)

89692.m00436

Species: T.vaginalis
Alias: 89692.m00436, TvagK1011
External Links:
Annotation:

Classification

Group: PKL
Family: RIO
Subfamily: RIO1

Sequence

Name Sequence Type Origin Length Description Download
89692.m00436.AA Protein None 465 None Fasta, JSON
89692.m00436.kin_dom Protein Kinase Domain None 248 None Fasta, JSON

Protein domain

Protein domains of 89692.m00436.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
RIO 89692.m00436.AA RIO 71-313 38 1.1e-87 298.57 SMART 1-253 (253) Show / Hide 
Range on Protein: 71-313
Range on HMM: 1-253/253
Sequence Identity: 38% (98 aa)

GKDMRRTEEQVLDNRTKVVLFKLLNRKILGDIE--GCISTGKEGNIYIGHRGESAPETWPEKFAIKIFKTCILKFKDRARYVTGEQRFQHHSKSKNSRKA
.|  ..| |.|.|.||. .|.|..||... .|   ||||||||.|.| .  |.. ..  ....|.||..| ...||...||..|..|| | .  .| || 
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKN--GNECAVKIYRTSTTEFKRMWRYIQGDFRFKHGYHHINWRKM

VVLWSEKEFRNLSRLHKNGVLCPEPLLVKHNIIFMELILNKNSPAPTLRLANLA--TKQFQ-DLYIDLAKTIRFMYHTCELVHADLSEYNLLVK------
| || |||||||.|... || ||.| ... ... ||.| ..  |||.|. ...   .. |   .| ..   .| ||| |.||||||||||.|..      
VRLWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDEN

GTSLYIIDVGQAVEIDNPNANQFLRNDICVITSFFKSRGVKTAP-LKLLFDFIVD
   ..|||..|.||.|.| . .||. || .|. ||. .||.. .  . .|..|..
DCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG
Kinase 89692.m00436.AA RIO1 80-307 44 4.2e-75 255.82 In-house 1-225 (225) Show / Hide 
Range on Protein: 80-307
Range on HMM: 1-225/225
Sequence Identity: 44% (103 aa)

QVLDNRTKVVLFKLLNRKILGDIEGCISTGKEGNIYIGHRGESAPETWPE--KFAIKIFKTCILKFKDRARYVTGEQRFQH-HSKSKNSRKAVVLWSEKE
||.| ||...|||.| | |. .| |||||||| | |       | ||  .    ||||.|| || |||| .|| || || | |.|. | || . .| |||
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVY------HASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKH-NPRKMIKIWAEKE

FRNLSRLHKNGVLCPEPLLVKHNIIFMELILNKNSPAPTLRLANLATKQFQ-DLYIDLAKTIRFMYHTCELVHADLSEYNLLVKGTSLYIIDVGQAVEID
.||| |.    . ||||. || |.  || |     .|| |  . .  .     .|  . .  | ||  | ||||||||||.|. .  ||.||| | || |
MRNLKRIYQSEIPCPEPIMVKSNVLMMEFIGKDGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHD

NPNANQFLRNDICVITSFFKSRGVKTAPLKLL
 | .  ||| |.  .  .|. ..| . |.  .
HPHSLEFLRMDCKNVNMYFMKHNVIIFPVRDI
Kinase 89692.m00436.AA RIO 79-310 32 8.4e-74 251.5 In-house 2-247 (276) Show / Hide 
Range on Protein: 79-310
Range on HMM: 2-247/276
Sequence Identity: 32% (81 aa)

EQVLDNRTKVVLFKLLNRKILGDIEGCISTGKEGNIYIGHRGESA-----PETWPEKFAIKIFKTCILKFKDRARYVTGEQRFQHHSKSKNSRKAVVLWS
||..| .|  ...|..|| ..  . .||..||| .||.   ..           |  .||||..| .. |||| .|. || .|.|     | |. . || 
EQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLWA

EKEFRNLSRLHKNGVLCPEPLLVKHNIIFMELILNKNSPAPTLRLANLA-TKQFQDLYIDLAKTIRFMYHTCELVHADLSEYNLLVKGTSL-------YI
|||.||..||...|  ||||...| ... ||.|     ||| . ....   ..   .| ..   .| .|. | |||.|..|.|.....  .       |.
EKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFYM

IDVGQAVEIDNPNANQFLRNDICVITSFFKSRGV-KTAPLKLLFDF
||. | ||.| |.|  ..| |.  .  ||. |.|  . |.  .|||
IDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRFVYEPFPEREMFDF
Kinase 89692.m00436.AA RIO1 113-307 34 1.2e-70 220.76 Pfam 1-200 (200) Show / Hide 
Range on Protein: 113-307
Range on HMM: 1-200/200
Sequence Identity: 34% (72 aa)

NIYIG---HRGESAPETWPEKFAIKIFKTCILKFKDRARYVTGEQRFQHHSKSKNSRKAVVLWSEKEFRNLSRLHKNGVLCPEPLLVKHNIIFMELIL-N
|.| .    .|.        ..|.||..| .. ||.. ||. ...|| |     | |. | .| |||||||.|... || ||.| ... ... ||.|   
NVYHAYSMEDGKD-------ECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDK

KNSPAPTLRLANLATK----QFQDLYIDLAK-TIRFMYHTCELVHADLSEYNLLVKGT-SLYIIDVGQAVEIDNPNANQFLRNDICVITSFFKSRGVK--
.  |||.|. ... ..    ... .| ..   ..| ||. |.|||.||||||.||     ..|||..||||.|.|.| .||. |.  |  ||. .||.  
DGWPAPRLKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVDER

TAPLKLL
..  . .
VMDFREI
Kinase 89692.m00436.AA RIO3 75-302 35 4.4e-51 170.2 In-house 1-233 (254) Show / Hide 
Range on Protein: 75-302
Range on HMM: 1-233/254
Sequence Identity: 35% (83 aa)

RRTEEQVLDNRTKVVLFKLLNRKILGDIEGCISTGKEGNIYIGH-----RGESAPETWPEKFAIKIFKTCILKFKDRARYVTGEQRFQHHSKSKNSRKAV
  | |. .| .|.....|..|  .|  | |||.||||  ..                 |   |||.||| . .||.| .|.  . ||.      | ||  
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGSMEDEKEDSKVIPTICAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIH

VLWSEKEFRNLSRLHKNGVLCPEPLLVKHNIIFMELILNKNSPAPTLRLANLATKQFQDLYIDLAKTIRFMYHTCELVHADLSEYNLLVKGTSLYIIDVG
 .|.|||  ||.|. . |. ||  .|.|. |. | .|     ||| |.   | ... .. | .  . .| .|| | ||||||||||.| .   ...||| 
RMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVWLIDVS

QAVEIDNPNANQFLRNDICVITSFFKSRGVKTA
|.||   |   .||  |   .. ||.  ||| |
QSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEA