Gene 94489.m00120 (T.vaginalis)
94489.m00120
Species: T.vaginalis
Alias: 94489.m00120, TvagK0876
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 94489.m00120.AA | Protein | None | 952 | None | Fasta, JSON |
| 94489.m00120.kin_dom | Protein Kinase Domain | None | 180 | None | Fasta, JSON |
Protein domains of 94489.m00120.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 94489.m00120.AA | VPS15 | 104-272 | 28 | 5.3e-17 | 55.46 | In-house | 96-296 (296) | Show / Hide |
Range on Protein: 104-272
Range on HMM: 96-296/296
Sequence Identity: 28% (58 aa)
TMVEKQWIAYQVCIILLRLHQSG-LYHSDLKPSNIFVSDSFFTYVTDLAPYKPETISPNRMNLYYHFFTTSSTSGYYLAPERFT---NEQKKIDM-----
.| || ||| | . | .| .| | |.|..|| |. . | || |..|| . . || ||. |.||||| . . .
QMIEKKWIAFQTLCALEQCHKQGNVCHGDIKSENILVTSWNWCYLTDFACFKPCYLPEDNPADFTFFFDTSRRRTCYIAPERFVSNTEQDQDSNNGNMRD
-------------------KAADLFSLGCVLYFIFSDG-KHLFDVMSGLKYGCGEDTI--SDKLSKVADEKMRNLIKSLISLD-ITKRLEAENMILQSFS
.| | ||.|||. .| .| .|| . .|| || . . | ||. |||....| | ||...| . . .
IHTDSIDRQQNPWLFGELTPAMDIFSAGCVIAELFCEGDQPPFDYSQLCKYRSGEYHPNREQIMEKIQDEHIRNLCHHMIQKDNPMKRMSCEEYLNKWRG
E
F
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| S_TKc | 94489.m00120.AA | S_TKc | 7-271 | 17 | 1.6e-13 | 21.47 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 7-271 Range on HMM: 1-231/231 Sequence Identity: 17% (51 aa) ITDYKHLESGTFFMVFQGKIQN--SNVVLKAYEYTAEIISLEEAKRSLDFFTKLEEYSLNLPGIVKYTDLKCEGTTAFLIRPKFQT---SLEDLLVFQEP . ... .|.| |.... . | .| | ..| .. | . | |||. | . . ... . .| |... . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR P-----ITMVEKQWIAYQVCIILLRLHQSGLYHSDLKPSNIFVSDSFFTYVTD--LAPYKPETISPNRMNLYYHFFTTSSTSGYYLAPERFTNEQKKIDM . .. . . ..||.| | .|. | | ||||.||.... ..| || || . .|.||| . . . HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------TTFCGTPWYMAPEVL-----GYGK KAADLFSLGCVLYFIFSDGKHLFDVMSGLKYGCGEDTISDKLSKVADEKMRNLIKSLISLDITKRLEAENMIL-------QSFS ...| |.||.|| .. |. .|. .... .|. .. ....|. . | .||. | . CKCDWWSCGCILYEMLC-GYPPFP---------QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 94489.m00120.AA | SCY1 | 179-271 | 18 | 3.8e-10 | 31.42 | In-house | 226-337 (337) | Show / Hide |
Range on Protein: 179-271 Range on HMM: 226-337/337 Sequence Identity: 18% (21 aa) YLAPERFTNEQ-----------KKIDMKAADLFSLGCVLYFIFSDGKHLFDVMSGL-----KYGCGEDTISDKLSKVADEKMRNL----IKSLISLDITK .|||| . . | | .. |.|.|||||. ..... .| ... | . .| .....| ... .. ... .. |.. |.|. WLAPEYIHEDQHTPASYNWGQEQKCTW-ASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWDHIPKELQEHLGHCYCHLLHQDPTC RLEAENMILQSFS | ...... .. RPDPQQFLQHCYF |
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| Kinase | 94489.m00120.AA | IRE | 179-264 | 25 | 4.6e-09 | 27.11 | In-house | 195-285 (292) | Show / Hide |
Range on Protein: 179-264 Range on HMM: 195-285/292 Sequence Identity: 25% (24 aa) YLAPERFTNEQKKIDMKAADLFSLGCVLYFIFSDGKHLFDVMSG-LKYGCGEDTIS-----DKLSKVADEK---MRNLIKSLISLDITKRLEAEN . .|| .. .| |. | ||.|||.|.... |.| | | |. ... |.|.. ... . ||.. |. | ||..... WHPPEMLQEFCQKRKTKSVDIFSMGCVFYYVMTNGQHPF----GNDKLHRQANILKGKYNLDQLKHHNHWHIVIACDLIHQMIHHDPQKRPTIKE |
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| Kinase | 94489.m00120.AA | Ciliate-E2 | 122-271 | 17 | 5e-08 | 23.62 | In-house | 176-365 (365) | Show / Hide |
Range on Protein: 122-271 Range on HMM: 176-365/365 Sequence Identity: 17% (37 aa) LHQSG-LYHSDLKPSNIFVSDSFFTYVTDLA-------PYKPETISPNRMNLYYHFF-TTSSTSG------------------YYLAPERFTNEQ----- ||. . | |.||.||.. ..|. ... .|. .....| . || |.| .|.||| . ... LHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQ -KKIDMKAADLFSLGCVLYFIFSDGKHLFDVMSGLKYGCGEDTISDKLSKVADEKMR---------------------NLIKS----LISLDITKRLE-A .| ...|..|||..||. . ||. | .. | .. . .... .||| .. | ||. . KQKGYDYKCDIWSLGVILYEMLF-GKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGW ENMILQSFS | . . EQILNHPWF |
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| Kinase | 94489.m00120.AA | Ciliate-E4 | 111-149 | 38 | 7.6e-08 | 22.74 | In-house | 112-150 (150) | Show / Hide |
Range on Protein: 111-149 Range on HMM: 112-150/150 Sequence Identity: 38% (15 aa) IAYQVCIILLRLHQSGLYHSDLKPSNIFVSDSFFTYVTD ||.. . | | ...| ||||||||....| . | IAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| Kinase | 94489.m00120.AA | C8 | 99-206 | 25 | 5.9e-07 | 20.31 | In-house | 116-226 (226) | Show / Hide |
Range on Protein: 99-206 Range on HMM: 116-226/226 Sequence Identity: 25% (29 aa) QEPPITMVEKQWIAYQVCIILLRLHQSGLYHSDLKPSNIFVSDSFFTY----VTDLAPYKPETISPNRMNLYYHFFTTSSTSGYYLAPERFTN--EQKKI .. ... .|. || |. . .|. | |.||.|. | . |.. ..| |. . ... | | . |.||| . .| |. KQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFG--FASQVSKNKSHIQSKKMNTCGTWA-YFAPEIEKKQDNQYKQ DMKAADLFSLGCVL . ||||.| || YRIQSDLFSVGLVL |
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| Kinase | 94489.m00120.AA | Ciliate-E1 | 13-200 | 17 | 2e-06 | 17.2 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 13-200 Range on HMM: 1-202/202 Sequence Identity: 17% (37 aa) LESGTFFMVFQGKIQNSN-----VVLKAYEYTAEIISLEEAKRSLDFFTKLEEYSLNLPGIVKYTDLKCEGTTAFLIRPKFQTSLEDLL---------VF ...| |..||..|.||.| ... ... . ..... .. . . | . .. |..| ... ....... .. .. | . IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC QEPPITMVEK--QWIAYQVCIILLRLHQSGLYHSDLKPSNIFVSDSFFTYVTDLAPYKPETISPNR--MNLYYHFFTTSSTSGYYLAPERFT------NE |. . . .. |..| | ||| ...|.|.||.|| .... || .. . .| .. . || || . |. QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC-------DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNK QKKIDMKAADLF ..||..| |.. NQKINYK-SDIY |
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| Kinase | 94489.m00120.AA | Ciliate-E3 | 111-142 | 34 | 9e-06 | 14.29 | In-house | 108-139 (202) | Show / Hide |
Range on Protein: 111-142 Range on HMM: 108-139/202 Sequence Identity: 34% (11 aa) IAYQVCIILLRLHQSGLYHSDLKPSNIFVSDS |. |. .. .|. . |||.||.|| |. . ICIQIIQGMIAIHEKNIIHSDIKPDNILVDKN |
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| Kinase | 94489.m00120.AA | IKS | 122-143 | 36 | 9e-06 | 13.32 | In-house | 169-190 (360) | Show / Hide |
Range on Protein: 122-143 Range on HMM: 169-190/360 Sequence Identity: 36% (8 aa) LHQSGLYHSDLKPSNIFVSDSF || .|. | |.||.|. . .. LHHIGIIHRDIKPPNCLIHQPY |
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| Kinase | 94489.m00120.AA | CLK | 109-156 | 39 | 1e-05 | 12.35 | In-house | 117-164 (350) | Show / Hide |
Range on Protein: 109-156 Range on HMM: 117-164/350 Sequence Identity: 39% (19 aa) QWIAYQVCIILLRLHQSGLYHSDLKPSNIFVSDSFFTYVTDLAPYKPE . .||| | . || .| | |||| || .|| ||.. .|... RHMAYQLCEAVKFLHDMKLTHTDLKPENICFVDSRFTHFDCTFKYNHK |
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| Kinase | 94489.m00120.AA | IRE | 122-141 | 45 | 0.01207 | 4.5 | In-house | 132-151 (292) | Show / Hide |
Range on Protein: 122-141 Range on HMM: 132-151/292 Sequence Identity: 45% (9 aa) LHQSGLYHSDLKPSNIFVSD ||... | |||| || ... LHSQNIVHRDLKPHNILIHM |
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| Kinase | 94489.m00120.AA | IKS | 196-209 | 42 | 0.12675 | 0.22 | In-house | 270-283 (360) | Show / Hide |
Range on Protein: 196-209 Range on HMM: 270-283/360 Sequence Identity: 42% (6 aa) AADLFSLGCVLYFI ..|..||| ..||. KCDMWSLGMICYFM |
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