Gene 92921.m00337 (T.vaginalis)
92921.m00337
Species: T.vaginalis
Alias: TvagK0494, 92921.m00337
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 92921.m00337.AA | Protein | None | 226 | None | Fasta, JSON |
| 92921.m00337.kin_dom | Protein Kinase Domain | None | 72 | None | Fasta, JSON |
Protein domains of 92921.m00337.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 92921.m00337.AA | CK1 | 1-133 | 48 | 1.2e-57 | 197.03 | In-house | 137-271 (271) | Show / Hide |
Range on Protein: 1-133 Range on HMM: 137-271/271 Sequence Identity: 48% (66 aa) MIGN-SRSPHTLALIDFGLSTSFCDIITKIHIPLREGKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVPLINGQSLSTAVSEIKQ ..| . |.. .|||||. . |. |. ||| ||.|.|.||.| |||| | ||| |||||||||.|.|.|| .||||||.. . . .|.|. LMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDMESLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKM STPIEELCYD-LPEEFGMFLQEVRALQFEEEPNYV |||.|.|| . .|.|| |.|. .| |.|||.|.| STPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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| Kinase | 92921.m00337.AA | CK1-Unclassified | 1-107 | 53 | 4.9e-52 | 151.87 | In-house | 136-244 (244) | Show / Hide |
Range on Protein: 1-107 Range on HMM: 136-244/244 Sequence Identity: 53% (58 aa) MIG-NSRSPHTLALIDFGLSTSFCDI-ITKIHIPLREGKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVPLINGQSLSTAVSEIK ..| . |.. .|||||| . |. |. ||| ||.|.|.||.| |||| | ||| |||||.|||.|.|||| ||||||||. | . |.| LMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLESLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMK QSTPIEELC .|||.|.|| MSTPVEQLC |
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| Kinase | 92921.m00337.AA | CK1-A | 1-135 | 48 | 1.8e-45 | 157.42 | In-house | 127-261 (261) | Show / Hide |
Range on Protein: 1-135 Range on HMM: 127-261/261 Sequence Identity: 48% (66 aa) MIGNSRSPHTLALIDFGLSTSFCDIITKIHIPLREGKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVPLINGQSLSTAVSEIKQS ..| | | ||||||. . |. |..||| || | |.|| | |||| | ||| ||||||||..|...|| .|.|||| . . . .|| | | LMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNRGKLPWQGMKAMTKKQKYEKISEKKMS TPIEELCYDLPEEFGMFLQEVRALQFEEEPNYVKY ||||.|| | || |... .|.|.|||.|.|. TPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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| Kinase | 92921.m00337.AA | CK1-D | 1-135 | 43 | 1.1e-44 | 154.82 | In-house | 127-261 (261) | Show / Hide |
Range on Protein: 1-135 Range on HMM: 127-261/261 Sequence Identity: 43% (59 aa) MIGNSRSPHTLALIDFGLSTSFCDIITKIHIPLREGKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVPLINGQSLSTAVSEIKQS ..| . .. .|||||. . | |. ||| || |.| || | |||| | ||| |||||.||| |.|.|| .|||||| . .. . ..| | | LMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICEKKMS TPIEELCYDLPEEFGMFLQEVRALQFEEEPNYVKY |.|..|| .|.|| .. .| |.|.. |.|. TKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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| Kinase | 92921.m00337.AA | CK1-G | 5-135 | 44 | 1.6e-41 | 138.44 | In-house | 134-266 (266) | Show / Hide |
Range on Protein: 5-135 Range on HMM: 134-266/266 Sequence Identity: 44% (59 aa) SRSPHTLALIDFGLSTSFCDIITKIHIPLREGKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVPLINGQSLSTAVSEIKQSTPIE .. .|.. .||||. . | || ||| || ||| || | ||| | | | |||||||.| . .||. |||||| | . . |..|.|| NKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMYFLRGSLPWQGLKADNNKERYQKIGDTKRKTNIE ELCYD--LPEEFGMFLQEVRALQFEEEPNYVKY || .||.|. .|. || |.|.|.| | DLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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| Kinase | 92921.m00337.AA | CK1 | 1-135 | 28 | 8.8e-41 | 139.97 | In-house | 164-339 (339) | Show / Hide |
Range on Protein: 1-135 Range on HMM: 164-339/339 Sequence Identity: 28% (50 aa) MIGN-------------SRSPHTLALIDFGLST-SFCDI-----------ITKIHIPLRE---GKSLVG-TTRSASINVHNGIEYSRRDDMESLAYILIY ..| .. ... .||||.. ..| |..|.| || |...| |.| .|||.|.|.| .||||..|..| ||. CMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIE FMKGS--LPWQNVPLING-------QSLSTAVSEIKQSTPIEELCYD-----LPEEFGMFLQEVRALQFEEEPNYVKY ..||. |||||. . . .| | |||.. || .|.|| .... .|.|.....|.| . WLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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| Kinase | 92921.m00337.AA | TTBKL | 1-143 | 24 | 1.4e-23 | 76.55 | In-house | 134-288 (288) | Show / Hide |
Range on Protein: 1-143
Range on HMM: 134-288/288
Sequence Identity: 24% (41 aa)
MIGNSRS----PHTLALIDFGLSTSFCDI----------ITKIHIPLRE---GKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVP
..|.. . ... |||||.. . . ..... . |. .. |||| .|.|.|.. | .| ||. |. |..|....| |||.|.
CWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNMHDRKEQGRHDDLWSWMYMIIELHCG-LPWTNM-
LINGQSLSTAVSEIKQSTPIEELCYD------LPEEFGMFLQEVRALQFEEEPNYVKYREMVRNLF
. . . |... | |..| .| ||..| . .|.|.. ..|.| ||....|
-----EDKMEIEHMKKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDY----EMIYECF
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| Kinase | 92921.m00337.AA | TTBK | 13-135 | 32 | 3.1e-16 | 53.91 | In-house | 142-257 (257) | Show / Hide |
Range on Protein: 13-135 Range on HMM: 142-257/257 Sequence Identity: 32% (40 aa) LIDFGLSTSFCDIITKIHIPLREGKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVPLINGQSLSTAVSEIKQSTPIEELCYDLPE ..|||| . . | || || | |||| | | |.||. || |.|. |..| ||| . . | |.|. | ..|. MLDFGLARQYTNACGEVRPP-REVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKDKD------QVGEMKEKYDHRMLLKHCPH EFGMFLQEVRALQFEEEPNYVKY || .|.. .. |..|. |.|. EFHQFMDHIKSLNYEDRPDYQLI |
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| Kinase | 92921.m00337.AA | Worm6 | 2-135 | 21 | 4.3e-15 | 50.86 | In-house | 137-279 (279) | Show / Hide |
Range on Protein: 2-135 Range on HMM: 137-279/279 Sequence Identity: 21% (31 aa) IGN-----SRSPHTLALIDFGLST--SFCDIITKIHIPLR-EGKSLVGTTRSASINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNVPLINGQS-LST || .. ||. ..|||.. .|. ... .. | . .||.| |... |.|.| .|.||.|| | .. . .| |||... . . . IGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNEL-RTPRWTACGFRGTVRYAPLACHKGQEQCRKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKK AVSEIKQSTPIEELCYDLPE-EFGMFLQEVRALQFEEEPNYVKY . .... ... | || .. . ......|.| . WCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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| Kinase | 92921.m00337.AA | VRK | 47-82 | 38 | 4.5e-07 | 19.18 | In-house | 208-243 (284) | Show / Hide |
Range on Protein: 47-82 Range on HMM: 208-243/284 Sequence Identity: 38% (14 aa) SINVHNGIEYSRRDDMESLAYILIYFMKGSLPWQNV |. |.| ||| | |.|.| ... |.||| .. SMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWMDC |
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