Gene 85859.m00391 (T.vaginalis)

85859.m00391

Species: T.vaginalis
Alias: TvagK0996, 85859.m00391
External Links:
Annotation:

Classification

Group: Other
Family: WNK

Sequence

Name Sequence Type Origin Length Description Download
85859.m00391.AA Protein None 288 None Fasta, JSON
85859.m00391.kin_dom Protein Kinase Domain None 243 None Fasta, JSON

Protein domain

Protein domains of 85859.m00391.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85859.m00391.AA WNK 193-267 28 4.3e-12 35.27 In-house 186-261 (261) Show / Hide 
Range on Protein: 193-267
Range on HMM: 186-261/261
Sequence Identity: 28% (22 aa)

DIWSLGICLLELLTRETAYSEYRTPIELFDALTEYKLPESLNLVKNQAAVDLIKKCLTPPS-QRIQINELLSDSIF
|. . | |.||  | |. |||   .   .   |   .|.|.....|    ..| ||.      |  |..||..  |
DVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTQGIKPNSFQKIQNPEVKEIIEKCIRHNKEERPSIQQLLNHDFF
Kinase 85859.m00391.AA STE 178-267 18 1.3e-10 33.81 In-house 228-359 (359) Show / Hide 
Range on Protein: 178-267
Range on HMM: 228-359/359
Sequence Identity: 18% (24 aa)

YTAPERLKGTI----AQCN---DIWSLGICLLELLTRETAYSEYRTPIELFDAL-----------------TEYKLPESLN---------------LVKN
. |||....       ...   ||||||....|..| .  ....  .  .| ..                 .  .||. |                    
WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWS

QAAVDLIKKCLTP-PSQRIQINELLS--DSIF
.   | |.|||.  |..|   ..||.   . .
PEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 85859.m00391.AA Ciliate-E2 178-267 20 2e-10 32.0 In-house 253-365 (365) Show / Hide 
Range on Protein: 178-267
Range on HMM: 253-365/365
Sequence Identity: 20% (28 aa)

YTAPERLKGT----------IAQCNDIWSLGICLLELLTRETAYSEYRTPIELFDALTEYKLPESLNLVKN----------------------------Q
| ||| |.|                ||||||..| |.|. .. .                     ..  |.                            |
YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQ

AAVDLIKK----CLTP-PSQRIQ-INELLSDSIF
 . |||||    .|   |..||. ....|   .|
ECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
S_TKc 85859.m00391.AA S_TKc 11-267 15 2.2e-10 -24.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 11-267
Range on HMM: 1-231/231
Sequence Identity: 15% (44 aa)

FTKL--------AQVRSSQHDIVCSVGLDTELCVQIYWYTCLNDNLTQEDQTKAFYQLCEAKKINSPYLMNILDVSQTVKPPQFIVVTEAADS--PSLAT
...|        ..|.  .|        . .  . |             ....   |...    . |.. ...|| |.     . .|.| .|    .| .
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-----------EHIRREIQILKK---HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFD

HIRQLVAPP-----SDKTIIRWFKSLATAVQALHNSPMKITHGEVSLNNVYFRSTPSNLKLT-LPISTLSLRSVSNQALDIDS------YTAPERLKGTI
.|..   ..     .  .. .... .. |.. .|.   .| |  .   |. . .   ..|..   ....            ..      | ||| |    
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE---HIKICDFGLARQL-----------TTFCGTPWYMAPEVL--GY

AQ-CNDIWSLGICLLELLTRETAYSEYRTPIELFDALTEYKLPESLNLVKNQAAVDLIKKCLT-PPSQRIQINELLS-------DSIF
     |.||.|..| |.|.... ..   .. ..|. .              . | |.|.|||.  |..|. . |.|        .  |
GKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85859.m00391.AA TKL 178-214 29 7.8e-09 27.96 In-house 239-292 (364) Show / Hide 
Range on Protein: 178-214
Range on HMM: 239-292/364
Sequence Identity: 29% (16 aa)

YTAPERLKGTIAQCN-----------------DIWSLGICLLELLTRETAYSEY
. ||| |.|..  ..                 |..| ||.| |.|||.. |..|
WMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY
Kinase 85859.m00391.AA ULK 193-267 19 5.4e-08 24.53 In-house 234-324 (324) Show / Hide 
Range on Protein: 193-267
Range on HMM: 234-324/324
Sequence Identity: 19% (18 aa)

DIWSLGICLLELLTRETAYSEY-RTPI----ELFD-----ALTEYKLPESLNLVK-----NQAAVDLIKKCLTP-PSQRIQINELLSDSIF
||||||. . |.|. .. .... .. .    .| .      ..... |   ....      .   |||...|.  ...|| . |...  .|
DIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 85859.m00391.AA Ciliate-E2-Unclassified 178-267 23 5.6e-08 23.78 In-house 232-352 (352) Show / Hide 
Range on Protein: 178-267
Range on HMM: 232-352/352
Sequence Identity: 23% (28 aa)

YTAPERLKG-TIA----QCNDIWSLGICLLELLTRETAYSEYRTPI---------------ELFDALTE--YKLPESLN----LVKNQAAVDLIK----K
||||| |.|         . ||||||..| |.|. .  .. .   .               .|..   .  .. |.. .       .. | |.|.    |
YTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQK

CLTP-PSQRIQINELLSDSIF
.|   |..||.....|   .|
MLKKNPNKRITFEQILNHPWF
Kinase 85859.m00391.AA AGC 193-267 21 5.7e-07 12.5 In-house 285-395 (395) Show / Hide 
Range on Protein: 193-267
Range on HMM: 285-395/395
Sequence Identity: 21% (24 aa)

DIWS--LGICLLELLTRETA-YSE--------YRTPIELFDALTEY----KLPESLN----------LVKNQAAVDLIKKCLT-PPSQRIQ---------
|.||  ||... |.||  .  |..        .|.| |.|.   ..    . .. ..              . |.|||||.|.  |..|.          
DWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDK

-INELLSDSIF
 ..|. .   |
GAEEIKNHPWF
Kinase 85859.m00391.AA ULK 193-267 20 7.2e-07 20.1 In-house 238-329 (329) Show / Hide 
Range on Protein: 193-267
Range on HMM: 238-329/329
Sequence Identity: 20% (19 aa)

DIWSLGICLLELLTRETAYSEY-RTPI-----ELFDA-------LTEYKLPESLN---LVKNQAAVDLIKKCLTP-PSQRIQINELLSDSIF
||||||. . |.|. .. .... .. .     .|..            .|    .    .  .   |||...|.  ...|| . ||..  .|
DIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 85859.m00391.AA Pkinase 193-267 16 2e-06 24.19 Pfam 194-293 (293) Show / Hide 
Range on Protein: 193-267
Range on HMM: 194-293/293
Sequence Identity: 16% (17 aa)

DIWSLGICLLELLTRETAYS------EYRTPIELFDALTEYKLPESLNLVKN-------------------QAAVDLIKKCLTP-PSQRIQINELLSDSI
|.||.|. | |.|.... ..      . ........   . .|...     .                   ... |.||.||.. |..|. . ..| .  
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPW

F
|
F
Kinase 85859.m00391.AA Ciliate-D1 193-211 42 1.4e-05 19.58 In-house 1-19 (19) Show / Hide 
Range on Protein: 193-211
Range on HMM: 1-19/19
Sequence Identity: 42% (8 aa)

DIWSLGICLLELLTRETAY
||||.|. |.|.|. .. .
DIWSFGCILYEMLFGQPPF
Kinase 85859.m00391.AA MKC 193-208 62 1.4e-05 17.27 In-house 183-198 (260) Show / Hide 
Range on Protein: 193-208
Range on HMM: 183-198/260
Sequence Identity: 62% (10 aa)

DIWSLGICLLELLTRE
||||.||||||.. ..
DIWSFGICLLEMANGR
Pkinase 85859.m00391.AA Pkinase 64-137 15 3.085342 1.92 Pfam 55-131 (293) Show / Hide 
Range on Protein: 64-137
Range on HMM: 55-131/293
Sequence Identity: 15% (13 aa)

KKINSPYLMNILDVSQTVKPPQFIVVTEAADSP----SLATHIR----QLVAPPSDKTIIRWFKSLATAVQALHNSPMKITH
|..|.|.   ..|. ..  ..   .|.| ..      .|...|.      .   |......... .. ... .|.  |.| |
KRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHS--MGIIH