Gene 83641.m00129 (T.vaginalis)

83641.m00129

Species: T.vaginalis
Alias: TvagK0526, 83641.m00129
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
83641.m00129.AA Protein None 308 None Fasta, JSON
83641.m00129.kin_dom Protein Kinase Domain None 189 None Fasta, JSON

Protein domain

Protein domains of 83641.m00129.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83641.m00129.AA Ciliate-E2 38-255 16 1.8e-15 49.57 In-house 58-358 (365) Show / Hide 
Range on Protein: 38-255
Range on HMM: 58-358/365
Sequence Identity: 16% (51 aa)

KLLKIFNRELLTNSELQP---ELDKELKLAQSLISRGLPTVEKVFQ--DHKYDVIVMEDLPNGNLKDYLKVK-----------KNMLYNDKIKLCIRILN
. ......|.  . |...    . .|... ..| .  .     .||  | ..  .||| .  |.|.||.| .           |..  .  ...   ||.
NQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQ

---------------GIICLHEHG-MNHGCLNPDNIYFDSFGNPKLIGYGL--HVKDQSTELS-----------------------------------NL
               ..  ||. .   |  . |.|| |     .|.|  ||   ..|.. . .                                   ..
GFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTP

IYRAPEEVK--------LQRRNNKEADMWSFGLVSHQIVANSFPFIVDDAQQYIKTLITGQQISLISVGGILD-------------------KIVER---
 | ||| ..        .| . ....|.||.| . .. . . .||            |  ..|.. .   ..|                    .  .   
GYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGK

-CLDPDPNTRITSDGARE
 .|. ||. |||  |. .
RMLQKDPEKRIT--GWEQ
Kinase 83641.m00129.AA Ciliate-E2-Unclassified 78-249 18 2.6e-14 46.08 In-house 89-342 (352) Show / Hide 
Range on Protein: 78-249
Range on HMM: 89-342/352
Sequence Identity: 18% (48 aa)

VFQDHKYDVIVMEDLPNGNLKDYLKVKKN----------------MLYNDKIK------LCIRILNGI-ICLHEHGMNHGCLNPDNIYFDSFG---NPKL
.||| ..  |||| ...|.|..|.| .|.                ..   ..|      ..  ||.|.  . |...  |  . |.|| ||. |   ..|.
CFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI

IGYGL----------HVKD------------QSTELSNLIYR----APEEVKLQRRNN---KEADMWSFGLVSHQIVANSFPFI-VDDAQ----------
|..|.            ..            ..|   ...|     |||  . |  ..   ...|.||.| . .... . .||   .. |          
IDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWIN

------QYIKTL-----------------ITGQQISLISVGGILDKIVERCLDPDPNTRIT
      .| . .                 .  ... .|.      ..  ..|. .|| |||
NAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFIN------DLLQKMLKKNPNKRIT
S_TKc 83641.m00129.AA S_TKc 3-257 20 3.7e-13 16.11 SMART 1-231 (231) Show / Hide 
Range on Protein: 3-257
Range on HMM: 1-231/231
Sequence Identity: 20% (55 aa)

NAFPEHLGNYNINKVITSDGIIQYAFATNEITYADKLLKIFNRELLTNSELQPELDKELKLAQSLISRGLPTVEKVFQDHKYDVIVMEDLPN--GNLKDY
  . ...|     ||     .           .| | .|               . .|... ..     . .   |||| ..  .||| ...  |.|.||
YEILRKIGKGAFGKVYKCRHKK------TGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

LKVKKN------MLYNDKIKLCIRILNGIICLHEHGMNHGCLNPDNIYFDSFGNPKLIGYGLHVKDQSTELSNLIYRAPEEVKLQRRNNK-EADMWSFGL
.| ..       .   .  ...  |....  .|.||  |  | |.|| .|.  . |..  ||  .  .|    . |.||| .      .| ..|.||.| 
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

VSHQIVANSFPFIVDDAQQYIKTLITGQQISLISVGGILDKIVERCLDPDPNTRITSDGARE---------MF
.    ..   ||   . |. .| .              .| ....||. ||. |.|   | .          |
ILYEMLCGYPPFP--QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83641.m00129.AA TKL 87-257 16 7.3e-13 42.66 In-house 115-364 (364) Show / Hide 
Range on Protein: 87-257
Range on HMM: 115-364/364
Sequence Identity: 16% (41 aa)

IVMEDLPNGNLKDYLKVKKNMLYNDKIKLCIRILNGIICLHEHG--------MNHGCLNPDNIYFDSFGN--------------PKLIGYGLHV-KDQST
||||  |.|.| .||        . ...... |  |.  || ..        . |  |...||  |. ..              .|.  .||   ..||.
IVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSG

------------------------ELSNLIYRAPEEVKLQRRNNKEA---------------DMWSFGLVSHQIVANSFPF---IVDDAQ------QYIK
                        .  .. . |||  . |  ... .               |..|||.|   |..   |.     .. .      ....
NMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFM

TLITGQQISLIS--------------VGGILDKIVERCLDPDPNTRITSDGAREMF
  .  ..  .|               .   . |. ..| |.||. | . .   . .
MVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 83641.m00129.AA MELK 12-220 23 1.1e-12 39.39 In-house 1-215 (254) Show / Hide 
Range on Protein: 12-220
Range on HMM: 1-215/254
Sequence Identity: 23% (52 aa)

YNINKVITSDGIIQYAFATNEITYADKLLKIFNRELLTNSELQPELDKELKLAQSLISRGLPTVEKVFQDHKYDVIVMEDLPNGNLKDYLKVKKNMLYND
|.. . | . |  .  .|.  .|     .|| ... |  ..| | .  |.   ..|  . .  .  . . ..   .|||  | |.. ||. .... | ..
YEVHDEIGTGGFAKVKLACHILTNQMVAIKIMDKNQLG-HDL-PRVKTEMDALKNLRHQHICQLYHYIETEDKIFMVMEYCPGGEMFDYI-IRQDRLEEE

KIKLCIR-ILNGIICLHEHGMNHGCLNPDNIYFDSFGNPKLIGYGLHVKDQSTELSN--------LIYRAPEEVKLQRRNNKEADMWSFGLVSHQIVANS
  .   | |.  |  .|  |  |  | |.|. ||   . ||| .||  | .              . | ||| .. ..    |||.|| |..   ..   
ETRHFFRQIVSAIAYVHSQGYAHRDLKPENLLFDEDHHLKLIDFGLCAKTKGRKDYHNLQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGF

FPFIVDDAQQYIKTLITG
 ||  |  .   | .. |
LPFDDDNMMIMYKKIMSG
Kinase 83641.m00129.AA Ciliate-E3 59-141 30 5.4e-10 27.66 In-house 51-134 (202) Show / Hide 
Range on Protein: 59-141
Range on HMM: 51-134/202
Sequence Identity: 30% (26 aa)

KELKLAQSLISRGLPTVEKVFQDHKYDV--IVMEDLPNGNLKDYLKVKKNMLYNDKIKLCIRILNGIICLHEHGMNHGCLNPDNI
.| ...|.. |  .  ..... | .. .  ||.|   ||.|. |.| . |   |  ...|| |. |.| .||    |. ..||||
QEFQNCQQINSQNVVKCHDQYYDQQNKMIFIVQEYCSNGDLYHYIK-QQNKTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNI
Kinase 83641.m00129.AA TKL-Unique 87-194 23 3.6e-07 21.54 In-house 77-217 (290) Show / Hide 
Range on Protein: 87-194
Range on HMM: 77-217/290
Sequence Identity: 23% (34 aa)

IVMEDLPNGNLKDYLK----------VKKNMLYNDKIKLCIRILNGIICLHEHG--MNHGCLNPDNIYFDSF-----GNPKLIGYGLHVKDQSTE----L
|||| .| |.| |.|            .... .. ..|. |.|  | . ||  .  . |. | . |.. |..      | |... || .| .|..    .
IVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGL-SKFNSKINKMTN

SNL------------IYRAPEEVKL--QRRNNKEADMWSFGLV
...            ...|||. .     ...| .| .||| |
NEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEK-SDVYSFGIV
Kinase 83641.m00129.AA TBCK 86-157 32 1e-06 19.92 In-house 53-131 (346) Show / Hide 
Range on Protein: 86-157
Range on HMM: 53-131/346
Sequence Identity: 32% (26 aa)

VIVMEDLPNGNLKD----YLKVKKNMLYNDKIKLCIRILNGIICLHEHGMNHGCLNPDNIYFDSFG----NPKLIGYGLH
..|||.. . || |    |.| ..    .        || |.  .| |.. |. | |.||| |. |      || .|||.
IVVMEHYKM-NLEDQIEIYAKRHTPKDCSQILCIYYQILCGLSYMHKHHIVHRFLHPHNIYLDDNGNQKLHVKLANYGLY
Kinase 83641.m00129.AA Ciliate-E1 94-193 18 1.1e-05 15.05 In-house 80-202 (202) Show / Hide 
Range on Protein: 94-193
Range on HMM: 80-202/202
Sequence Identity: 18% (23 aa)

NGNLKDYLK-------------VKKNMLYNDKIKLCIRILNGIICLHEHGMNHGCLNPDNIYFDSFGNPKLI--GYGLHVKDQSTELS-----NLIYRAP
. .|||||.              ....    |... .... |.| || ..  |....|.|| ....|| ..   | ..  | .... .        |. |
CCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPP

EEVK---LQRRNNKEADMWSFGL
|...   ..  .|.. ...|   
EQYNCPEQEHNKNQKINYKSDIY
Kinase 83641.m00129.AA TyrKc 18-257 19 0.000902 -161.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 18-257
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

ITSD--------GIIQYAFATNEITYADKLLKIFNRELLTNSELQPELDKELKLAQSL--------ISRGLPTVE--KVFQDHKYDVIVMEDLPNGNLKD
|| .        |..  . ..  |. | | ||            . .. .|...  .|           |  | .  . |   .   ||||  |.|.|||
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN-FMYIEPLMIVMEYMPHGDLKD

YLKVKKN-MLYNDKIKLCIRILNGIICLHEHGMNHGCLNPDNIYFDSFGNPK--------LIGYG-------LHVKDQSTELSN--LIYR--APEEVKLQ
||. ...     |... |. | .|   ||...  |  |   |.  .. .  |         |. .          . .... ..  | .|  |||     
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NY

RRNNKEADMWSFGLVSHQIVAN-SFPFIV-----DDAQQYIKTLITGQQISLISV----------GGILDKIVERCLDPDPNTRITSDGAREMF
.. . . | |||| .   |  .   |         ..|. |. . .|                    . . | ..| . ||. | |    .| |
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase 83641.m00129.AA Ciliate-B1 235-258 41 0.001838 8.12 In-house 267-290 (290) Show / Hide 
Range on Protein: 235-258
Range on HMM: 267-290/290
Sequence Identity: 41% (10 aa)

IVERCLDPDPNTRITSDGAREMFE
| . || |||. |||.|   .  .
IQKYCLQPDPENRITIDQIIDRLM
Kinase 83641.m00129.AA NZAK 170-199 43 0.002672 6.37 In-house 238-266 (329) Show / Hide 
Range on Protein: 170-199
Range on HMM: 238-266/329
Sequence Identity: 43% (13 aa)

YRAPEEVKLQRRNNKEADMWSFGLVSHQIV
| |||  .. | | |  | ||||..  |..
YMAPENKNNHRINEK-SDVWSFGCTVWQMF
Kinase 83641.m00129.AA NZAK 81-161 30 0.004968 5.45 In-house 73-156 (329) Show / Hide 
Range on Protein: 81-161
Range on HMM: 73-156/329
Sequence Identity: 30% (26 aa)

DHKYDVIVMEDLPNGNLKDYL-KVKKNMLYND--KIKLCIRILNGIICLHEHGMNHGCLNPDNIYFDSFGNPKLIGYGLHVKDQ
|  |  |.|| .  ||| ..| . ||   ...   ||.   |  ..  || |.  |  . . |.  |  .| ||| .|  . .|
DDNYHCIYMEWMEGGNLTQFLMNDKKQLRFKEHRIIKMIADIAETMSYLHKHHIIHRDIKSNNVILDFNKNLKLIDFGSSIIQQ
Kinase 83641.m00129.AA Ciliate-B1 87-143 34 0.012549 5.16 In-house 94-151 (290) Show / Hide 
Range on Protein: 87-143
Range on HMM: 94-151/290
Sequence Identity: 34% (20 aa)

IVMEDLPNGNLKDYLKV-KKNMLYNDKIKLCIRILNGIICLHEHGMNHGCLNPDNIYF
|.||   .|.| .|.    .|..   ..  || | .||. ||.|.  |  | |.||..
IIMEYCEQGDLYNYIYNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILI
Kinase 83641.m00129.AA Pkinase 234-260 24 0.012908 10.33 Pfam 268-293 (293) Show / Hide 
Range on Protein: 234-260
Range on HMM: 268-293/293
Sequence Identity: 24% (7 aa)

KIVERCLDPDPNTRITSDGAREMFET--I
.....||..||. |.|   |.. ..   .
DFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 83641.m00129.AA Pkinase 170-205 30 0.051671 8.2 Pfam 177-212 (293) Show / Hide 
Range on Protein: 170-205
Range on HMM: 177-212/293
Sequence Identity: 30% (11 aa)

YRAPEEVKLQRRNNKEADMWSFGLVSHQIVANSFPF
|.||| .. ..   ...||||.|.. .. .   .||
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF
Kinase 83641.m00129.AA Ciliate-E3 172-199 35 0.106 1.43 In-house 175-202 (202) Show / Hide 
Range on Protein: 172-199
Range on HMM: 175-202/202
Sequence Identity: 35% (10 aa)

APEEVKLQRRNNKEADMWSFGLVSHQIV
|. |.  |    || |. | | |  |..
AAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase 83641.m00129.AA Pkinase 78-130 22 2.834923 2.05 Pfam 68-128 (293) Show / Hide 
Range on Protein: 78-130
Range on HMM: 68-128/293
Sequence Identity: 22% (14 aa)

VFQDHKYDVIVMEDLPNG----NLKDYLK--VKKNM--LYNDKIKLCIRILNGIICLHEHG
.|.|...  .||| ...|     |.||..   ....   ... .. .  || |.  .|..|
WFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMG