Gene 96732.m00510 (T.vaginalis)

96732.m00510

Species: T.vaginalis
Alias: TvagK0833, 96732.m00510
External Links:
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
96732.m00510.AA Protein None 658 None Fasta, JSON
96732.m00510.kin_dom Protein Kinase Domain None 241 None Fasta, JSON

Protein domain

Protein domains of 96732.m00510.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96732.m00510.AA SCY1 21-214 17 1.7e-15 50.15 In-house 1-269 (337) Show / Hide 
Range on Protein: 21-214
Range on HMM: 1-269/337
Sequence Identity: 17% (47 aa)

WKVHSAVKKSTQEKVCLWQLDIE--TLKSKVKSQATIDTYVKNCLSGLQMQKRLLHPHILKILE-INEQSPALSFASEPVETCITLDTRLS--RD-----
||.|...||.| ... ..  |.   . ..| .   .|.. .|.  . |   ||| ||.||.... ..| .  ...|.|..  . .|.. |.  ..     
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRL---KRLRHPNILQYIHPLEESKDCMMYATEEI--FQPLENVLKKWDNKKSCQ

-----------------------------EILYLAKQLCETLEFLHNSAKIAHLCLSPDSLCLTSDFSVKLTN---------FTWACQIA--EDEKSVLV
                             |. .   |. . | ||||.....|. ..|.|  .. . . |.           ..  |.|   ... . . 
TQKTQDVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFP

LKPS-----------------SSPLNVPSSFMSPEQFNS-------------KNVTLKSDVFSFSSLICSLIAG
...                  ..|.  ..... ||.. .               .| .||.||.. ||.....|
CQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNG
Kinase 96732.m00510.AA S_TKc 22-260 16 1.9e-11 -9.16 SMART 14-220 (231) Show / Hide 
Range on Protein: 22-260
Range on HMM: 14-220/231
Sequence Identity: 16% (42 aa)

KVHSAVKKSTQEKVCLWQLDIETLKSKVKSQATIDTYVKNCLSGLQMQKRLLHPHILKILEINEQSPALSFASEPVET-------CITLDTR------LS
||. ...|.|...| . ...                  .. .. .|. |.  ||.| |.... .    | .  | ...        |    |      ..
KVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

RDEILYLAKQLCETLEFLHNSAKIAHLCLSPDSLCLTSDFSVKLTNFTWACQIAEDEKSVLVLKPSSSPLNVPSSFMSPEQFNSKNVTL-KSDVFSFSSL
  .. ....|.|. ||..|.  .| |  | |. . |..   .|.. |  |.|.              . . .   .|.|| .     .  |.|. |.  .
E-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

ICSLIAGRTIYECPNINTDSLIPRTIEDDTREALAACFDDDPNDRPSFSELKK
.  ...|.. ..  ....   . .   .. .. .  |.. ||..||.  |. .
LYEMLCGYPPFP--QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQ
Kinase 96732.m00510.AA TKL 115-262 13 2.5e-08 26.11 In-house 137-364 (364) Show / Hide 
Range on Protein: 115-262
Range on HMM: 137-364/364
Sequence Identity: 13% (30 aa)

LAKQLCETLEFLHNSAK-------IAHLCLSPDSLCLTSDFS--------------VKLTNFTWACQIAEDEKSVLVLKP---------SSSPLNVPS--
.|.. .  ...||..         |.|  | .. . . ...               .|.. |  .  . .....    .          ... .. .   
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT

-SFMSPEQFNSK----------------NVTLKSDVFSFSSLICSLIAGRTIYECP---------------NINTDSLIPRTIE------------DDT-
  .|.|| .. .                  . |.||.||  ... ...... |...                .. |   . .|             .|. 
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCP

---REALAACFDDDPNDRPSFSELKKCT
   .. .  | | ||..||||.|..|  
PSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 96732.m00510.AA NZAK 184-262 26 4e-06 16.02 In-house 238-329 (329) Show / Hide 
Range on Protein: 184-262
Range on HMM: 238-329/329
Sequence Identity: 26% (24 aa)

FMSPEQFNSKNVTLKSDVFSFSSLICSLIAG---RTIYEC---------PNINTDSLIPRTIEDDTREALAACFDDDPNDR-PSFSELKKCT
.| ||  |   .. ||||.||  ..  .. .    |||           . .|    ||  . |  .. .  |.| ||. |   ||..    
YMAPENKNNHRINEKSDVWSFGCTVWQMFGYNPPNTIYSPKEMASMVSDQKFNYIPQIPFHVPDKMKDFITQCWDIDPKKRPKDFSHMIEKL
Kinase 96732.m00510.AA TyrKc 43-262 18 1.1e-05 -130.86 SMART 1-280 (280) Show / Hide 
Range on Protein: 43-262
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

ETLKSK---------VKSQATIDTYVKNCLSGLQMQ---------KRL--LHPHILKILEINEQS-------PALSFASEPVETCITLDTRL-------S
 ||. |         .| ...|.  || . ..  ..         ..|   ||.|.... .  |.       . |    | ..    |. .|       .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRKHRPKLC

RDEILYLAKQLCETLEFLHNSAKIAHLCLSPDSLC----------LTSDFSVKLTNFTWACQIAED----EKSVLVLKPSSSPLN--VPSSFMSPEQFNS
 .. |. . | ..  |.||              .           ..... || . |  .  | .|    | .    | ...  .  .|   |.|| .| 
MKDLLSFCWQIACGMEYLHSK-----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

KNVTLKSDVFSFSSL---ICSL------------IAGRTIYECPNINTDSLIPRT--------IEDDTREALAACFDDDPNDRPSFSELKKCT
.  | ||||.||  .   |...            .  . ..|.        .|            |.  .    | . ||.|||.|||...| 
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 96732.m00510.AA STE-Unique 217-264 20 2.4e-05 14.31 In-house 569-616 (616) Show / Hide 
Range on Protein: 217-264
Range on HMM: 569-616/616
Sequence Identity: 20% (10 aa)

IYECPNINTDSLIPRTIEDDTREALAACFDDDPNDRPSFSELKKCTGI
|.  |. . . .||     ...... .|.. .|..||| ..| . .  
IHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase 96732.m00510.AA Pkinase 22-134 20 2.9e-05 19.72 Pfam 14-131 (293) Show / Hide 
Range on Protein: 22-134
Range on HMM: 14-131/293
Sequence Identity: 20% (26 aa)

KVHSAVKKSTQEKVCLWQLDIETLKSKVKSQAT-IDTYVKNCLSGLQMQKRLLHPHILKILEINEQSPALSFASEPVET---CITLD--------TRL--
.|  ...|.|...|.. ... .. ||... ... .        | .|. ||| ||.|...... | .. . .  | .|    .. |         ...  
CVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYF

SRDEILYLAKQLCETLEFLHNSAKIAH
| .|.   ..|... ||..|.  .| |
SEWECKFYMYQILRGLEYCHS-MGIIH
Kinase 96732.m00510.AA SLK 101-155 36 3.5e-05 13.3 In-house 88-141 (259) Show / Hide 
Range on Protein: 101-155
Range on HMM: 88-141/259
Sequence Identity: 36% (20 aa)

ITLDTRLSRDEILYLAKQLCETLEFLHNSAKIAHLCLSPDSLCLTSDFSVKLTNF
. |.  |  | | |..|..||.|..|| | |. |  |    . .| |  |.|  |
VELEHPLTEDQIQYVCKHMCEALNWLH-SNKVIHRDLKAGNILMTMDGDVRLADF
Kinase 96732.m00510.AA TK 244-262 47 4.3e-05 12.18 In-house 468-486 (486) Show / Hide 
Range on Protein: 244-262
Range on HMM: 468-486/486
Sequence Identity: 47% (9 aa)

CFDDDPNDRPSFSELKKCT
|.. ||.|||.||.|... 
CWHYDPEDRPTFSQLHEQL
Kinase 96732.m00510.AA Axl 235-260 42 4.5e-05 13.65 In-house 242-267 (267) Show / Hide 
Range on Protein: 235-260
Range on HMM: 242-267/267
Sequence Identity: 42% (11 aa)

DDTREALAACFDDDPNDRPSFSELKK
|.  . .  |.. || ||||||.|..
DELYDLMYQCWEADPKDRPSFSVLRE
Kinase 96732.m00510.AA Fer 229-263 22 0.000106 12.06 In-house 248-283 (283) Show / Hide 
Range on Protein: 229-263
Range on HMM: 248-283/283
Sequence Identity: 22% (8 aa)

IPRTIEDDTREALA-ACFDDDPNDRPSFSELKKCTG
.|    .. .. ..  |.. ||.|||...|....  
MPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase 96732.m00510.AA Ciliate-E2 106-204 16 0.000113 11.94 In-house 141-282 (365) Show / Hide 
Range on Protein: 106-204
Range on HMM: 141-282/365
Sequence Identity: 16% (24 aa)

RLSRDEILYLAKQLCE---------------TLEFLHNSAKIAHLCLSPDSLCLTSDFSVKLTNFTWACQIAEDEKSVLVLKPSSSPLNVPS--------
...  ||.|. ||...                ||.||.  .| |  . |. . .     .|.. |  . .. .|..  .  |. .  .   .        
YFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPG

------------------SFMSPEQFNSKN---------VTLKSDVFSF
                   .|.|| .|.|.          . |.|..|.
YMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL
Kinase 96732.m00510.AA RIPK 244-262 52 0.002997 6.89 In-house 272-290 (290) Show / Hide 
Range on Protein: 244-262
Range on HMM: 272-290/290
Sequence Identity: 52% (10 aa)

CFDDDPNDRPSFSELKKCT
| . ||||||.| | .  |
CWQQDPNDRPCFQECEEWT
Kinase 96732.m00510.AA Pkinase 184-260 13 0.007373 11.19 Pfam 177-289 (293) Show / Hide 
Range on Protein: 184-260
Range on HMM: 177-289/293
Sequence Identity: 13% (15 aa)

FMSPEQFN-SKNVTLKSDVFSFSSLICSLIAGRTIYE-C----PNINTDSLIPRTIE-------------------------------DDTREALAACFD
.|.||  . ..  . |.|..|.  ..  .. ||...  .    . .. . .| |. .                               .. .. .  |..
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

DDPNDRPSFSELKK
 ||..||.. ....
KDPKKRPTAEQILQ
Kinase 96732.m00510.AA RIPK 183-219 34 0.010479 5.01 In-house 187-229 (290) Show / Hide 
Range on Protein: 183-219
Range on HMM: 187-229/290
Sequence Identity: 34% (15 aa)

SFMSPEQFN---SKN---VTLKSDVFSFSSLICSLIAGRTIYE
|.| || |.   .|    || |.|| ||  ..  . ...  ||
SYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYE
Kinase 96732.m00510.AA STE-Unique 110-167 27 0.015891 4.11 In-house 403-466 (616) Show / Hide 
Range on Protein: 110-167
Range on HMM: 403-466/616
Sequence Identity: 27% (18 aa)

DEILYLAKQLCETLEFLHNSAK--IAHLCLSPDSLCLTSDF-----SVKLTNFTWACQIAEDEKS
.|......|. | ||.|| | .  | |  | |.   ...|      .||. .|  | . ..|...
TEVIWYTYQILEGLEYLH-SQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHATCCQPDHFE
Kinase 96732.m00510.AA Fer 185-205 33 0.036006 3.32 In-house 185-205 (283) Show / Hide 
Range on Protein: 185-205
Range on HMM: 185-205/283
Sequence Identity: 33% (7 aa)

MSPEQFNSKNVTLKSDVFSFS
..|| ....  . |.||.||.
LAPETWQTGIYSPKTDVWSFG