Gene 82048.m00056 (T.vaginalis)

82048.m00056

Species: T.vaginalis
Alias: 82048.m00056, TvagK0830
External Links:
Annotation:

Classification

Group: Other
Family: SCY1

Sequence

Name Sequence Type Origin Length Description Download
82048.m00056.AA Protein None 774 None Fasta, JSON
82048.m00056.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 82048.m00056.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82048.m00056.AA SCY1 29-280 16 1.5e-31 106.52 In-house 1-337 (337) Show / Hide 
Range on Protein: 29-280
Range on HMM: 1-337/337
Sequence Identity: 16% (57 aa)

WKVHSAVNKTTHDRVSLWLIDQE-------KITAEIQDQAVRDKYLSGSLAGIQKLRKLRHPHLLKILEVQESTSS-LGFASEPISSSLQTLIGSLNGDD
||.|... |.|  ..|..  |         .  .|.......        . ...| .||||..|..... | ..  . .|.|.|...| .. . .  . 
WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLK--------KQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKK

A------------------------------SYIC---FQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFN---------FDWSVPINGTKDINL
                               ...|   ||. ||..|||| ..|.|..|.||.||...| . |..          .|  ..| .  . ..
SCQTQKTQDVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMP

PFTQYFT------------------EITYPPLPYSSPEVVQC-------------RQSTCLADVFSFALVFYECISGKPLLLCKDKRE--------YDIG
.| ....                     .|.. .. ||..               .  |. .|.||. .. .....|| .. .. .           . .
WFPCQEWREMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWN

RNPILSISGIGTNYMNL----FRGCLNIDASTRPDFTNILESEAF
.  . . . |  .. ..      . |. |.  |||. ..|... |
AMSHCWWDHIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF
S_TKc 82048.m00056.AA S_TKc 17-280 18 5.2e-14 28.51 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-280
Range on HMM: 1-231/231
Sequence Identity: 18% (53 aa)

YDNVNPIFTIGYWKVHSAVNKTTHDRVSLWLIDQEKITAEIQDQAVRDKYLSGSLAGIQKLRKLRHPHLLKILEVQESTSSLGFASEPISS---SLQTLI
|. ...|   .. ||. ...| |. .| .  |.                     .  || |.| .||.. |...| .. ..| .  | ..    .| ..|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYI

GS---------LNGDDASYICFQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFNFDWSVPINGTKDINLPFTQYFTEITYPPLPYSSPEVVQCRQ
 .         ..  .| ... |...|....|.. .  |  . || |.|||   .|.  |  .  .              | .   |  | .|||.   .
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTP-WYMAPEVL---G

STC-LADVFSFALVFYECISGKPLLLCKDKREYDIGRNPILSISGIGTNYMNLFRGCLNIDASTRPDFTNILE-------SEAF
 ..  .|. |.  ..||...|.|.    ... ... .              .. |.||. | . ||    .|.        . |
YGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82048.m00056.AA TKL 124-278 14 6.6e-13 42.83 In-house 137-364 (364) Show / Hide 
Range on Protein: 124-278
Range on HMM: 137-364/364
Sequence Identity: 14% (34 aa)

ICFQLADAMQFLHNNAK-------MAHLGISPEAIFLDENLS--------------VKLFNFDWSVPINGTKDINLPF----------TQYFTEITYP-P
.. . | .|..||..         ..|  . .. |..|||.               .|.  |  |  ...... |             ..  | .|    
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT

LPYSSPEVVQ----------------CRQSTCLADVFSFALVFYECISGKPLLLCKDKR------------EYDI--GRNPILS-----------ISGIG
. . .||| .                ... .  .||.||..|..|......   . . .            ....  |. | .             . . 
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCP

TNYMNLFRGCLNIDASTRPDFTNILESE
. . .|   | . |.. || |. ||.  
PSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 82048.m00056.AA TKL-Unique 127-225 19 4.7e-09 28.25 In-house 118-225 (290) Show / Hide 
Range on Protein: 127-225
Range on HMM: 118-225/290
Sequence Identity: 19% (22 aa)

QLADAMQFLHNNAK-MAHLGISPEAIFLDEN-----LSVKLFNFDWSVPINGTKDINLPFTQY-----FTEITYPPLPYSSPEVVQC--RQSTCLADVFS
. |..| .||.. . ..|. . . .. .|.|     ...|.  |  . ... .|... ...        |.....   ...|||      | .. .||.|
DIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDF--GLSKFNSKINKMTNNEHKGTRNQTRCGSF--RWMAPEVLRMNFCQYSEKSDVYS

FALVFYECISGK
|. | .|....|
FGIVLWEIATRK
Kinase 82048.m00056.AA Ciliate-E2 77-280 15 7.9e-09 26.42 In-house 86-365 (365) Show / Hide 
Range on Protein: 77-280
Range on HMM: 86-365/365
Sequence Identity: 15% (45 aa)

LRKLRHPHLLKILEVQE--STSSLGFASEPISS-SLQTLIG--------------SLNGDDASYICFQLAD---------------AMQFLHNNAKMAHL
|..| ||...|. |. .  ..... .  | ..  .|. .|               ...   ..||  |...               |...||.. .  | 
LEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHR

GISPEAIFLDENLSVKLFNFDWS-----VPINGTK---DINLPFTQYFTEITYP----------------PLPYSSPEVVQCRQ---------STCLADV
 | || |..     .|.  |  |       .|.|.     ...| .. |..|.                  ..| .||...  .          .  .|.
DIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDI

FSFALVFYECISGKPLLLCKDKREYDIGRNPILSISGIG---------TNY----------MNLFRG----CLNIDASTRPD-FTNILESEAF
.|.  ..||...|||         ...  .  ....            ...          ..|..     .|. | . |.. .  ||. . |
WSLGVILYEMLFGKPPF-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 82048.m00056.AA Ciliate-E6 124-164 34 3e-06 16.29 In-house 58-97 (154) Show / Hide 
Range on Protein: 124-164
Range on HMM: 58-97/154
Sequence Identity: 34% (14 aa)

ICFQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFNF
.| ||. |.. || . .  .  |... ||||.|. .|.  |
FCCQLFHAVEYLHSK-NYVLQNITLKNIFLDKNMNIKICDF
Kinase 82048.m00056.AA HH498 196-225 32 8e-06 14.01 In-house 193-223 (284) Show / Hide 
Range on Protein: 196-225
Range on HMM: 193-223/284
Sequence Identity: 32% (10 aa)

SPEVVQ-CRQSTCLADVFSFALVFYECISGK
.|||   | . .  .||||.|.. .|  ...
APEVFSQCQKYSIKVDVFSYAMCIWEMHTRE
Kinase 82048.m00056.AA CAMK 77-164 17 1e-05 13.6 In-house 85-240 (425) Show / Hide 
Range on Protein: 77-164
Range on HMM: 85-240/425
Sequence Identity: 17% (28 aa)

LRK-------LRHPHLLKILEVQES-----------TSS---------LGFAS---EPISS-----SLQTLI------------------GSLNGDDASY
..|       |.||...|..|| |.           | |         . .     | .|       |   |                  | .. ..|..
MKKLQGIGNKLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARR

ICFQLADAMQFLHNNAKMAHLGISPEAIFLDEN-----------------LSVKLFNF
.  |...|....|..   .|. . || | ||.|                   .|.  |
YFRQICSAVHYCHSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF
Kinase 82048.m00056.AA Ciliate-C1 127-156 43 1.7e-05 9.64 In-house 137-165 (328) Show / Hide 
Range on Protein: 127-156
Range on HMM: 137-165/328
Sequence Identity: 43% (13 aa)

QLADAMQFLHNNAKMAHLGISPEAIFLDEN
|| .. |..|.|   .|. . || |.||||
QLINVIQYIHQNN-ICHRDLKPENILLDEN
Kinase 82048.m00056.AA Ciliate-E2-Unclassified 121-161 24 4.1e-05 13.71 In-house 140-188 (352) Show / Hide 
Range on Protein: 121-161
Range on HMM: 140-188/352
Sequence Identity: 24% (12 aa)

AS-----YICFQLADAMQFLHNNAKMAHLGISPEAIFLDENL---SVKL
|.     ... |. .. ..|| . .  |  | || |..|.|     .|.
AKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI
TyrKc 82048.m00056.AA TyrKc 17-280 16 0.00052 -157.79 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-280
Range on HMM: 1-280/280
Sequence Identity: 16% (50 aa)

YDNVNPIFTIGYWKVHSAVNKTTHDRVSLWLIDQEKITA---EIQDQAVRDKYLSGSLAGIQKLRKL--RHPHLLKILEVQEST-------SSLGFASEP
      .    . .|. .. |               |.     ... |     .   .  .. ..||  .||...... |  .          |    | 
ITLGKKLGEGAFGEVYKGTWK---------------IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEY

IS-----SSLQTLIGSLNGDDASYICFQLADAMQFLHNNAKMAHLGISPEAIFLDENLSVKLFNFDWSVPINGT-KDINLPFTQYFTE----ITYPPLPY
 .     . |.   . |. .|  ..|.| |. |..|| . .  |  .    . ..||. ||   |  |  |    .      ..| .      .  .||.
MPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPI

--SSPEVVQCRQSTCLADVFSFALVFYECISG----KPL-----LLCKDKREYDIGRNPILSISG--------IGTNYMNLFRGCLNIDASTRPDFTNIL
   .||. . .  |   ||.||  . .|  .      |      .  .. .||   ..                 .   .. . | . |.. || |..| 
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-

ESEAF
  | |
-HECF
Kinase 82048.m00056.AA MLK 196-225 27 0.001246 8.62 In-house 201-233 (291) Show / Hide 
Range on Protein: 196-225
Range on HMM: 201-233/291
Sequence Identity: 27% (9 aa)

SPEVV---QCRQSTCLADVFSFALVFYECISGK
.|||    .| . .  .||.|...|..| ....
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase 82048.m00056.AA Pkinase 192-227 27 0.00512 11.75 Pfam 175-211 (293) Show / Hide 
Range on Protein: 192-227
Range on HMM: 175-211/293
Sequence Identity: 27% (10 aa)

LPYSSPEVVQ-CRQSTCLADVFSFALVFYECISGKPL
..| .|||.. ..  .  .|..|. ...|| ..|.|.
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase 82048.m00056.AA MLK 260-278 36 0.062196 2.65 In-house 273-291 (291) Show / Hide 
Range on Protein: 260-278
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CLNIDASTRPDFTNILESE
| | |.. ||.|  |..  
CWNQDPHKRPSFRQIVQHL
Kinase 82048.m00056.AA MLK 124-142 31 0.090937 2.07 In-house 129-147 (291) Show / Hide 
Range on Protein: 124-142
Range on HMM: 129-147/291
Sequence Identity: 31% (6 aa)

ICFQLADAMQFLHNNAKMA
...| | .|..||..|...
WALQCARGMHYLHSMAPKP
Kinase 82048.m00056.AA Ciliate-E2-Unclassified 255-280 26 0.148309 1.19 In-house 327-352 (352) Show / Hide 
Range on Protein: 255-280
Range on HMM: 327-352/352
Sequence Identity: 26% (7 aa)

NLFRGCLNIDASTRPDFTNILESEAF
.|.. .|. . . |..|  ||.   |
DLLQKMLKKNPNKRITFEQILNHPWF
Kinase 82048.m00056.AA TKL-Unique 252-278 33 0.192572 1.07 In-house 264-290 (290) Show / Hide 
Range on Protein: 252-278
Range on HMM: 264-290/290
Sequence Identity: 33% (9 aa)

NYMNLFRGCLNIDASTRPDFTNILESE
.| .| . | . | | || |..|... 
EYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 82048.m00056.AA Pkinase 77-138 12 3.314433 1.81 Pfam 54-127 (293) Show / Hide 
Range on Protein: 77-138
Range on HMM: 54-127/293
Sequence Identity: 12% (9 aa)

LRKLRHPHLLKILEVQESTSSLGFASEPISS-----SLQTLIG-----SL--NGDDASYICFQLADAMQFLHNN
...|.||. ...... |. ... .  |         .| ..|      ..    ...  .. |.. .....|..
MKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM
Kinase 82048.m00056.AA Pkinase 258-280 34 3.537425 1.71 Pfam 271-293 (293) Show / Hide 
Range on Protein: 258-280
Range on HMM: 271-293/293
Sequence Identity: 34% (8 aa)

RGCLNIDASTRPDFTNILESEAF
..||. | . || .. ||... |
KWCLCKDPKKRPTAEQILQHPWF