Gene 85874.m00030 (T.vaginalis)
85874.m00030
Species: T.vaginalis
Alias: TvagK0385, 85874.m00030
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 85874.m00030.AA | Protein | None | 398 | None | Fasta, JSON |
| 85874.m00030.kin_dom | Protein Kinase Domain | None | 189 | None | Fasta, JSON |
Protein domains of 85874.m00030.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PH | 85874.m00030.AA | PH | 6-101 | 34 | 1.2e-23 | 85.86 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 6-101 Range on HMM: 1-82/82 Sequence Identity: 34% (33 aa) VLKEGWATKCGGFWKTWHRRWFVLTGNILEYSKQPGVTPQGSINLNETGTISYAPDCKKQPALQIVCPDRTYYMVPDTPQEVDDWIDALNKAKQSE |.|||| .|.. .|..|||||... | | |.. .|.|||.|.. |.. | ...|.. |||||. ....| ..|..|..|| .. VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P------CFEIHH-DRTYYFQCESEEEMQEWMQAIQKAIHNN |
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| PH | 85874.m00030.AA | PH | 6-99 | 40 | 4.4e-22 | 82.26 | Pfam | 1-92 (92) | Show / Hide |
Range on Protein: 6-99 Range on HMM: 1-92/92 Sequence Identity: 40% (38 aa) VLKEGWATKCGGFWKTWHRRWFVLTGNILEYSKQPGVTPQGSINLNETGTISYAPDCKKQPALQIVCPDR-TYYMVPDTPQEVDDWIDALNKAKQ | |||| .| | ..|.|..|||||..| | | | .. .|.|||.|.. .. ..|| |.. .||.. || ||| ....| .||..|...| VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR |
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| Kinase | 85874.m00030.AA | Ciliate-E2-Unclassified | 167-315 | 17 | 4.1e-11 | 34.83 | In-house | 79-300 (352) | Show / Hide |
Range on Protein: 167-315
Range on HMM: 79-300/352
Sequence Identity: 17% (39 aa)
KIPYVCPLVDVVQDENCIMFISEP-RPSSLDQVLKAKPT------------------TPVLAD-----SIFTEILEGLRSLHQLG-FIYGDFHISNVLID
. |.. .... ||...| .. | . .| | .| ... | | .| .||.|| .||. . .|. | .|.|.|
PHPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFD
YQG---HVSLSIPGFVLKPNPN---------------QERY------LSYL----SPQILNDEKPSSR----SDMWAACIMLFYIYTGYVPYVSSTIPS-
.| .. .. |. |.. | |... ..|. .| .| .... . .|.|. . |... .|| |. . . .
NNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQH
---------------LKEEQKQ
|....||
QQLITQWINNAYRKQLYQNIKQ
|
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| S_TKc | 85874.m00030.AA | S_TKc | 113-354 | 17 | 5e-11 | -15.26 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 113-354 Range on HMM: 1-231/231 Sequence Identity: 17% (46 aa) YAIIRYVYHGLHSSILEVRDTLTNRTYIAKRYSTEGLGNQTDELDRYRRELMGKKIPYVCPLVDVVQDENCIMFISEPRPS---SLDQVLKAKP------ | |.| . .| .. .|.. |.| . |. . . |.. .. . |... | || || ... .. | . .| ...| .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -TTPVLADSIFTEILEGLRSLHQLGFIYGDFHISNVLIDYQGHVSLSIPGFVLKPNPNQERY---LSYLSPQILNDEKPSS-RSDMWAACIMLFYIYTGY .. | ... .|...| .|..|.|. | .|.|.| |. .. |. . . . |..| .| . . ..|.|. ..|. ..|| PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGY VPYVSSTIPSLKEEQKQPIKYPSLIPSETQKRLKSWL---DPDSREELKVGTDMH-------LPNY |. ... |. |. | . . . ||. | . . .. | PPFP-----QMQMMFKKIG-------SPEAKDFIRKCLQKDPEKR--PTA-EALQDEWDIKCHPWF |
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| Kinase | 85874.m00030.AA | Ciliate-E2 | 212-321 | 15 | 1.8e-10 | 32.13 | In-house | 165-309 (365) | Show / Hide |
Range on Protein: 212-321 Range on HMM: 165-309/365 Sequence Identity: 15% (25 aa) IFTEILEGLRSLHQLG-FIYGDFHISNVLIDYQGHVSLSIPGFVL--KPNPNQERYL-------------------------------------SYLSPQ ....|...|..||. . |. | .|.|. . | | | | ........ |..|. YIACIILALEYLHSKNNIIHRDIKPENILF-------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPE ILNDEK---------PSSRSDMWAACIMLFYIYTGYVPYVSSTIPSLKEEQKQPIKYPS ||| .| . .|.|.. ..|.. .|. |. ... ....|..|. ILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF-------QQQIKQCKIDFPC |
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| Kinase | 85874.m00030.AA | ULK | 267-324 | 18 | 1.8e-09 | 29.84 | In-house | 213-291 (324) | Show / Hide |
Range on Protein: 267-324 Range on HMM: 213-291/324 Sequence Identity: 18% (15 aa) YLSPQILN----DEKPS-SRSDMWAACIMLFYIYTGYVPYVSSTIPSLKE---------------EQKQPIKYPS--LIP | .||||. .... . .|.| ...... .|..|..|. . .... ...|||..|. .| YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDP |
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| Kinase | 85874.m00030.AA | ULK | 267-324 | 15 | 8.1e-09 | 27.01 | In-house | 217-297 (329) | Show / Hide |
Range on Protein: 267-324 Range on HMM: 217-297/329 Sequence Identity: 15% (13 aa) YLSPQILN----DEKPS-SRSDMWAACIMLFYIYTGYVPYVSSTIPSLK-----EE-----------QKQPIKYP---SLIP | .||||. .... . .|.| ...... .|..|.... . ... .. .|||...| . .. YMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ |
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| Kinase | 85874.m00030.AA | AGC | 215-246 | 31 | 1.7e-08 | 16.52 | In-house | 154-194 (395) | Show / Hide |
Range on Protein: 215-246 Range on HMM: 154-194/395 Sequence Identity: 31% (13 aa) E-------ILEGLRSLHQ-LGFIYGD-FHISNVLIDYQGHV | |. .| .||. .|.|. | |.|.| .||. EMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHI |
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| Kinase | 85874.m00030.AA | Delta | 214-301 | 30 | 1.5e-07 | 23.33 | In-house | 107-200 (259) | Show / Hide |
Range on Protein: 214-301 Range on HMM: 107-200/259 Sequence Identity: 30% (29 aa) TEILEGLRSLHQLGFIYGDFHISNVLIDYQGHVSLSIPGFVLKPNPNQERYLS-------YLSPQILNDEKPSSRSDMWAACIMLFYIYTGYVPY .||. ||. ||. | || | . |||.|..||. . | | | ..| | |..| |. .| . | |. .... . | |. CEIICGLQFLHKKGIIYRDLKLDNVLLDCDGHIKIADFGMC-KENMYGEKKASTFCGTPDYIAPEIIKGQKYNHSVDWWSFGVLMYEMLIGQSPF |
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| Kinase | 85874.m00030.AA | RSK-Unclassified | 215-249 | 37 | 5.7e-07 | 17.37 | In-house | 109-143 (283) | Show / Hide |
Range on Protein: 215-249 Range on HMM: 109-143/283 Sequence Identity: 37% (13 aa) EILEGLRSLHQLGFIYGDFHISNVLIDYQGHVSLS |. | || ..||| | |.. .. ||| |. EVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLT |
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| Kinase | 85874.m00030.AA | RSKL | 215-248 | 37 | 1e-06 | 10.57 | In-house | 281-315 (436) | Show / Hide |
Range on Protein: 215-248 Range on HMM: 281-315/436 Sequence Identity: 37% (13 aa) EILEGLRSLHQLG-FIYGDFHISNVLIDYQGHVSL |.. | .||. | | .|.. | |.| .|| | EMVVALHALHAEGHVICRDLNPDNILLDQKGHIQL |
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| Kinase | 85874.m00030.AA | Iota | 214-248 | 45 | 7e-06 | 15.01 | In-house | 107-141 (271) | Show / Hide |
Range on Protein: 214-248 Range on HMM: 107-141/271 Sequence Identity: 45% (16 aa) TEILEGLRSLHQLGFIYGDFHISNVLIDYQGHVSL .|| | ||. | || | . |||.| .||. | AEICLALNFLHERGIIYRDLKLDNVLLDHEGHIKL |
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| Kinase | 85874.m00030.AA | Ciliate-E2b | 212-248 | 29 | 0.000173 | 9.74 | In-house | 107-143 (272) | Show / Hide |
Range on Protein: 212-248 Range on HMM: 107-143/272 Sequence Identity: 29% (11 aa) IFTEILEGLRSLHQLGFIYGDFHISNVLIDYQGHVSL .. .|. .|. ||... ||.| .|...|..|.. | YIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKL |
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| Kinase | 85874.m00030.AA | Ciliate-E2b | 267-301 | 30 | 0.000224 | 9.39 | In-house | 171-210 (272) | Show / Hide |
Range on Protein: 267-301 Range on HMM: 171-210/272 Sequence Identity: 30% (12 aa) YLSPQILN----DEKP-SSRSDMWAACIMLFYIYTGYVPY |. |.|.. |. . .|.|. |.|. . ||||. YMAPEIIQSLQPGGKGYTYKVDIWSVGICLYEFMCGYVPW |
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