94102.m00175

Species: T.vaginalis
Alias: 94102.m00175, TvagK0607
External Links:
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MAK

Sequence

Name Sequence Type Origin Length Description Download
94102.m00175.AA Protein None 359 None Fasta, JSON
94102.m00175.kin_dom Protein Kinase Domain None 280 None Fasta, JSON

Protein domain

Protein domains of 94102.m00175.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94102.m00175.AA RCK 4-283 52 3.4e-180 576.75 In-house 1-298 (298) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-298/298
Sequence Identity: 52% (155 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQRYTSWEECCQLKEVTSLRKIK-HQNVVRLLEVFREEE--HLFLVFELLHGSMYKSIRD---HDGPF
| .|. .|||..|.|.| .| |||..||||||||.. ||||| .|.|..||||.. | |.. |.||.|...  .|..|||..    |. ..|    . ..
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYL

SEAQ--VRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDG----------DTLKICDFGLAREIRSKPPYTEYVSTRWYRAPEIVLRHQFYNSPVDIWAA
.| |  ... |.|||.|| . |. ||||||.||||..  |          |..||.||||.||||||||||.|||||||||||. || ..||||.|||| 
PENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAV

GCIMAELFTSKPLFQGTSETDQLFKICSVLGTPGPGNWPDGAKLAQRLNIRLPSFAPTPLHTIIPNASPEAIELLTEMLQYDPAKRPSASKALQHPWF
||||.|| . .||| |.|| ||.||||.|.||| .  |||| |||. .|...|.  ..|| ..|||.|...|||...|||.|| ||..|..||||| |
GCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQHPYF

Kinase 94102.m00175.AA MAK 4-283 44 6.30000000001e-158 506.66 In-house 1-352 (352) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-352/352
Sequence Identity: 44% (157 aa)

YETIEVVGDGAFGTVLKCKN------------------------------RETGQLVAIKKMKQRYTSWEECCQLKEVTSLRKIK-HQNVVRLLEVFR--
| .|. .|||..|.|.. |                                .|| .||||.||. . ||||| .| || ||.|.. | |.|.|.||.|  
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

EEEHLFLVFELLHGSMYKSIRDHDG-PFSEAQVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDG------------------DTLKICDFGLAREIRS
|..||..||| .    | .. | |   |.|  .|  | ||| ||...|. |||||||||||..  |                  . .|| ||||||||||
ENDHLYFVFEYMKENLYQMMKDRDRRHFPEPVIRNIMYQILQGLAFMHKHGFFHRDMKPENIMCMGPTQYFEKEYMNQIGYQDNELIKIADFGLAREIRS

KPPYTEYVSTRWYRAPEIVLRHQFYNSPVDIWAAGCIMAELFTSKPLFQGTSETDQLFKICSVLGTPGPGN----------------WPDGAKLAQRLNI
||||| |||||||||||. ||   |.||.|.|| |||||||.| .||| |.|| ||.||||.|||||                    |||| .||  .| 
KPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQLAHMMNF

RLPSFAP---TPLHTIIPNASP-EAIELLTEMLQYDPAKRPSASKALQHPWF
|.|   |   .|| ..|||.|. .||||...|||.|| ||| |. ....|.|
RFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF

Kinase 94102.m00175.AA CMGC 4-283 26 7.4e-128 422.58 In-house 1-513 (513) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-513/513
Sequence Identity: 26% (136 aa)

YETIEVVGDGAFGTVLKCKN--------------RETGQLVAIKKMKQRYTSWEECC-----------QLKEVTSLRKIK-----------------HQN
|| |...| |..|.| ||..              .||...|||||.|..    |...            | |.  |....                 | |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVRLLEVFREEE-----------------HLFLVFELLHGSMYKSIRDHDG--------PFSEAQ------------VRFCM------KQILLGLQ--YV
.|.|...|. ..                 ||.||||..  . |. |... .        |.|| .            ... |      .||| ||   | 
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HRCG--FFHRDMKPENLLWDGDT---------------------LKICDFGLAR--EIRSKP--------------------PYTEYVSTRWYRAPEIVL
|. .  ..|||.||||.| . ..                     ||||||||||  ...|..                    |||.||.||||||||| |
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

RH---------QFYNSPVDIWAAGCIMAELFTS--------KPLFQGTSE-----------TDQLFKICSVLGTPG---------------PGNWPD---
.          . |..|.|.|..|||.||..|         ||||.| ||            ||||||. |||||                . .||.   
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

----------------------GAKLAQRLNIRLPSFAPTPLHTIIPN-----------------------------------ASPEAIELLTEMLQYDP
                      .|..... |.|.| . | |.. ..|.                                   ..|.||.||  ||||||
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

AKRPSASKALQHPWF
.||..|. |||||.|
DKRITAEQALQHPYF

Kinase 94102.m00175.AA CDK 4-283 34 2.2e-107 344.67 In-house 1-284 (284) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-284/284
Sequence Identity: 34% (112 aa)

YETIEVVGDGAFGTVLKCKNRETG-----QLVAIKKMK---QRYTSWE-ECCQ---LKEVTSLRKIKHQNVVRLLEVFREE-----------EHLFLVFE
|| .| .| |..|.| |.....||     |.||.|| .   .  .. | |      . |.. |... |.|.|.|..|.  .             |..|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEG-REEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

LLHGSMYKSIRDHDGPFSEAQVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDGDT------LKICDFGLAREIRS-------KPPYTEYVSTRWYRAP
 ..   .| ..          ..  |.|.| || | |. .. |||.|| |.| . .       ||| ||||||.  .         .||  | |.|||||
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

EIVLRHQFYN--SPVDIWAAGCIMAELFT---SKPLFQGTSETDQLFKICSVLGTPGPGNWPDGAKLAQRLNIRLPSFAPTPLHTIIPNASPEAIELLTE
|. |  . |.   |.|.|..|||.||.||    ||||.|.||.||||||. ..||| . |||.  ||                            .||  
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-------------------------DLLNK

MLQYDPAKRPSASKALQHPWF
||.|||.|| ||. |||||.|
MLCYDPKKRISAEQALQHPYF

Kinase 94102.m00175.AA S_TKc 4-283 33 3.8e-103 349.88 SMART 1-231 (231) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-231/231
Sequence Identity: 33% (98 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQRYTSWEECCQLKEVTSLRKIKHQNVVRLLEVFREEEHLFLVFELLHG---SMYKSIRDHDGP----
|| ....| ||||.| ||....||..||||..|        .  ..|.  |.| .| |.|.|..||.. .||..|.|.. |   .... |... ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FSEAQVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDGDTLKICDFGLAREIRSKPPYTEYVSTRWYRAPEIVLRHQFYNS-PVDIWAAGCIMAELFT
 |.| ..|| |.||...|.| |. |. ||| ||||.| |  ..|||||||||..      | .. |.||.|||..     |.  ..|.|. |||..|...
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLC

SKPLFQGTSETDQLFKICSVLGTPGPGNWPDGAKLAQRLNIRLPSFAPTPLHTIIPNASPEAIELLTEMLQYDPAKRPSASKALQ-------HPWF
 .|.|.   . ...||..                                        ||||....  .||.||.|||.| .|||       ||||
GYPPFP---QMQMMFKKIG---------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 94102.m00175.AA Pkinase 4-283 34 8.20000000001e-102 349.34 Pfam 1-293 (293) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-293/293
Sequence Identity: 34% (104 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQRYTSWEECCQLK---EVTSLRKIKHQNVVRLLEVFREEEHLFLVFELLHG-----SMYKSIR-DHD
|......| |.||.| ||... ||..||.|..| | ...... ..    |.  .....| |.|||...|... |. .|.|.. |     . .  |. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPF--SEAQVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWD--GDT---LKICDFGLARE--IRSKPPYTEYVSTRWYRAPEIVLRHQFYNSPVDIWAA
|.|  || ...|.|.||| ||.| |..|. |||.||||.| |  |..   .||||||||.   . ... .| .. |.||.|||... .| | ..||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCIMAELFTSKPLFQGT----SETDQLFKICSVLGTPGPGNWPDGAKLAQRLNIRLPSFAPTPLHTIIPNASPEAIELLTEMLQYDPAKRPSASKALQHP
|||..|... .|.|.|     .  ||...|| ..|.| . .||       .  .|    . . . |  .|.|.|...... .|..||.|||.|  .||||
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

WF
||
WF

Kinase 94102.m00175.AA CDC2 4-283 40 5.9e-99 304.78 In-house 1-301 (301) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-301/301
Sequence Identity: 40% (123 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQRYTSWE----ECCQLKEVTSLRKIK-HQNVVRLLEVFREEEHLFLVFELLHGSMYKSIR---DHDG
|. || .| | .| | |||...|.|.||.|| .  . . .    . . ..|   | ..| |.|.|.| .|. .   |..||| |.    |  .     . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTA-IREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNK

PFSEAQVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDGD-TLKICDFGLAREIRS-KPPYT--EYVSTRWYRAPEIVLRHQFYNSPVDIWAAGCIMAE
..... |.  |.||| |. . |. . .||| || |.| | . ..|| |||||| .   . .||    | |.||||||| |. ..|. |||.|. |||.||
HMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAE

L---FTSKPLFQGTSETDQLFKICSVLGTPGPGNWPDGAKLAQRLNIRLPSFAPTPLHTIIPN---------ASPEAIELLTEMLQYDPAKRPSASKALQ
.    | ||||.| || ||||||  .||||   .||.  .| .  .   | . |. | .|.||         . ||.|.|| .||||||.|| || .|||
MFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQL-PDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQ

HPWF
||.|
HPYF

Kinase 94102.m00175.AA CDK7 4-283 36 1.3e-95 255.05 In-house 1-288 (288) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-288/288
Sequence Identity: 36% (106 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMK---QRYTSWE--ECCQLKEVTSLRKIKHQNVVRLLEVFREEEHLFLVFELLHGSMYKSIRDHDGPFS
||.|. .| | |.|| |    .||| ||||| |    |       .   . |.  |. ..| ||. |. .|     . |||...   .   |.|    . 
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILT

EAQVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDGD-TLKICDFGLAREIRS-KPPYTEYVSTRWYRAPEIVLRHQFYNSPVDIWAAGCIMAELFTSK
 | .   |...|.|| | ||    |||.|| ||| . .  ||| |||||| . |    ||  | ||||||||       | . ||.|. |||.|||    
PAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRV

PLFQGTSETDQLFKICSVLGTPGPGNWPDGAKLAQRLNIRLPSFAP---TPLHTIIPNASPEAIELLTEMLQYDPAKRPSASKALQHPWF
| . |.|. ||| .|.. |||| . .||.  ...  . ..  .| .   |||. |   || ....|.  |.  .| || ... .|..| |
PYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFK--DFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF

Kinase 94102.m00175.AA MOK 4-283 36 3.8e-82 257.17 In-house 1-283 (283) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-283/283
Sequence Identity: 36% (104 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQRYTSWEECCQLKEVTSLRKIK-HQNVVRLLEVF--REEEHLFLVFELLHGSMYKSIRDHDGPFSEA
| .|  .|.|.|  |.| .    |.  | |.|||.. | |.  .|.|.  .|..  | |.. | ||   |    | |. ||.   .|  ||    . .. 
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDMNIYELIRGRRHYLPQK

QVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDGDTLKICDFGLAREIRSKPPYTEYVSTRWYRAPEIVLRHQFYNSPVDIWAAGCIMAELFTSKPLFQ
...  | |..  |. .|| | ||||.||||.|   | ||. |||  | . || |||||.||||||||| .|   .|   .|.|..||.  |.   .||| 
KIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQDHLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYEIASLHPLFP

GTSETDQLFKICSVLGTPGPGNWPDGAKLAQRLNIRLPSFAPTPLHTIIPNASPEAIELLTEMLQYDPAKRPSASKALQHPWF
|  | ||. ||  |.|||         . .  .|   |.     .  ..||... ..|.. .|  |||  | .| ...|||.|
GVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEKLTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF

Kinase 94102.m00175.AA CDK5 4-283 35 2.3e-80 253.58 In-house 1-287 (287) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-287/287
Sequence Identity: 35% (105 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQRYTSWEE---CCQLKEVTSLRKIKHQNVVRLLEVFREEEHLFLVFELLHGSMYKSIRDHDGPFSEA
|| .| .|.| .||| | .|.||. .||.|.   |  |  |   .  . |.  |. .||.|.|||  |   |  | |||| .   . | . .  |  . .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRV--RLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMH

QVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDGD-TLKICDFGLARE----IRSKPPYTEYVSTRWYRAPEIVLRHQFYNSPVDIWAAGCIMAELF-T
 ..  | | | ||.. |     |||.|| |||     .||  ||||||     .|    |.  | | |||.| . .  . |. ..|.| .|||.||.  .
IIKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRC---YSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANA

SKPLFQGTSETDQLFKICSVLGTPGPGNWPDGAKLAQRL--NIRLPSFAPTP-LHTIIPNASPEAIELLTEMLQYDPAKRPSASKALQHPWF
 .||| |....|||..|  ..|||   .||  .|| .       .|.. ... .  |.|. . .  .|| .|||..|..| || .||.||.|
GRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF

Kinase 94102.m00175.AA CDKL 4-217 43 4.2e-74 252.51 In-house 1-218 (286) Show / Hide
Range on Protein: 4-217
Range on HMM: 1-218/286
Sequence Identity: 43% (95 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQ-RYTSWEECCQLKEVTSLRKIKHQNVVRLLEVFREEEHLFLVFELLHGSMYKSIRDHDGPFSEAQV
||.. .|| |. |.|.||.|.||||.||||| |  ..   .    . |.  |.  ||.| | |.||||    |.||||    ..      .     | .|
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIKMLKQLKHENIVNLIEVFRRKRKLHLVFEYCDHTVLHELEEYPNGVDEHVV

RFCMKQILLGLQYVHRCGFFHRDMKPENLLWD--GDTLKICDFGLAREIRSKPP--YTEYVSTRWYRAPEIVLRHQFYNSPVDIWAAGCIMAELFTSKPL
|  | ||| .... |     ||| ||||.|     ...|.||||.|| . .||   ||.|| |||||||| ..    | .||||||.||.|||...  ||
RKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVMAEMIDGQPL

FQGTSETDQLFKICSVLGT
. | |. |||..|  .||.
WPGQSDIDQLYHIQKCLGP

Kinase 94102.m00175.AA MAPK 54-283 36 1.5e-71 244.0 In-house 58-328 (328) Show / Hide
Range on Protein: 54-283
Range on HMM: 58-328/328
Sequence Identity: 36% (100 aa)

LRKI-KHQNVVRLLEVFREE-----------EHLFLVFELLHGSMYKSIRDHDGPFSEAQVRFCMKQILLG--LQYVHRCGFFHRDMKPENLLWDGD-TL
|| . .| |...||..|. |           . . .|.|| .  ... |.  . | |.  ... | ||| |  |.| |  .  ||| ||.|.| . . .|
LRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMETDLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDL

KICDFGLAREIRSKPPY---------------TEYVSTRWYRAPEIVLR--HQFYNSPVDIWAAGCIMAELFT-SKPLFQGTSETDQLFKICSVLGTPGP
||||||||| | ..  .               ||||.||||||||| |    . |.  ||.|..|||.||. |  ||||.|..  ||...| .||||| .
KICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSE

GNW--PD-GAKLAQRLNIR--LPSFAPTPLHTIIPN----ASPEAIELLTEMLQYDPAKRPSASKALQHPWF
  .       . .. .  .  ||   . |.....||    |.|.|| ||  ||. || || ..  ||||| |
EFIQCICMSEHARNYIQSLGNLPKYPKKPWEKMFPNANFNANPQAIDLLEKMLVFDPDKRITVEEALQHPYF

Kinase 94102.m00175.AA TyrKc 4-283 22 1.7e-15 27.8 SMART 1-280 (280) Show / Hide
Range on Protein: 4-283
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

YETIEVVGDGAFGTVLKCKNRETGQLVAIKKMKQRYTSWEECCQ--LKEVTSLRKI--KHQNVVRLLEVFREE-------EHLFLVFELL-HGSMYKSIR
 . ... | ||||.| |.. .   . ||.|..|          .  ..|   ..|.  .|.|.|||. | ...       | |..|.|.  ||.  . .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

DHDGPFSEAQVRFCMKQILLGLQYVHRCGFFHRDMKPENLLWDGDT-LKICDFGLAREIRSK-------PPYT------EY--VSTRWYRAPEIVLRHQF
.| . .. ..    . ||  | .| |. .. |||    | | . .   ||.||||.|.| ..         |.      .   .  ||. |||   ..  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI-NYGK

YNSPVDIWAAGCIMAELFTS-KPLFQG-----TSETDQLFKICSVLGTPGPGN----WPDGAKLAQRLNIRLPSFAPTPLHTIIPNASPEAIELLTEMLQ
...  |.|. |  | |.||  ..   |      | .. . .. .    | | |                               . ...|  .. ..  .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------F-VCCPDEMYQIMKQCWH

YDPAKRPSASKALQHPWF
.||..||. |    |  |
EDPEDRPTFSEI--HECF

Kinase 94102.m00175.AA Pkinase_Tyr 4-125 25 2.1e-12 42.62 Pfam 1-136 (270) Show / Hide
Range on Protein: 4-125
Range on HMM: 1-136/270
Sequence Identity: 25% (34 aa)

YETIEVVGDGAFGTVLKCKNR----ETGQLVAIKKMKQRYTSWE--ECCQLKEVTSLRKI-KHQNVVRLLEVFR-EEEH--LFLVFELL-HGSMYKSIRD
 . ... | ||||.| |.. .    .|.. ||.|..|. ... .      ..|.  .... .|.|.|||. |   ..|.  ...|.|.  ||....  |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

H---DGPFSEAQVRFCMKQILLGLQYVHRCGFFHRD
|   ..|..  .      ||  |..| .. .. |||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRD

Kinase 94102.m00175.AA CDKL 242-283 30 7.2e-11 33.39 In-house 244-286 (286) Show / Hide
Range on Protein: 242-283
Range on HMM: 244-286/286
Sequence Identity: 30% (13 aa)

PTPLHTIIPNAS-PEAIELLTEMLQYDPAKRPSASKALQHPWF
. ||    ||.| ..|. ..  .|. ||..|........|| |
MEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF

Kinase 94102.m00175.AA MAPK 4-35 34 6.9e-10 30.15 In-house 1-38 (328) Show / Hide
Range on Protein: 4-35
Range on HMM: 1-38/328
Sequence Identity: 34% (13 aa)

YETIEVVGDGAFGTVLKCKNRETGQL------VAIKKM
|. .. .| ||.|.| ... ..|.|       |||||.
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKI

Kinase 94102.m00175.AA Pkinase_Tyr 134-194 32 0.002545 11.87 Pfam 146-209 (270) Show / Hide
Range on Protein: 134-194
Range on HMM: 146-209/270
Sequence Identity: 32% (22 aa)

DGDTLKICDFGLAREIRSKPPYTEYVST------RWYRAPEIVLRHQFYNSPVDIWAAGCIMAELFT
.. . ||||||||| | ..  |  ....      .|. |||       ...  |.|. |  | |.||
ENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWM-APECINYGK-FTTKSDVWSFGVLMWEIFT