Gene 84085.m00082 (T.vaginalis)

84085.m00082

Species: T.vaginalis
Alias: 84085.m00082, TvagK0873
External Links:
Annotation:

Classification

Group: Other
Family: VPS15

Sequence

Name Sequence Type Origin Length Description Download
84085.m00082.AA Protein None 994 None Fasta, JSON
84085.m00082.kin_dom Protein Kinase Domain None 196 None Fasta, JSON

Protein domain

Protein domains of 84085.m00082.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 84085.m00082.AA S_TKc 23-294 17 4.6e-12 0.04 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-294
Range on HMM: 1-231/231
Sequence Identity: 17% (52 aa)

LQVARSLFDGTFMLSFLVNDKKSNSEFVVKCYKIPDNDAQYKDVRAASLEAIGKSQKIFENLVKNKSTLRGNLDIQYFVTNNAAYLVRPYMPL---DLVS
 .. | .  |.|   ... .||.. .. .|. |           . .  |    ..   .|.|| . . .           .  |.|  |..    || .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------EHIRREIQILKK-HHPNIVKLYDVFQD----------DHLYMVMEYCDGDLGDLFD

RMDDFPK------LTFYDQLWISYQLVRSVFSLHSHEIYHGAIKPENVLLSDRFEVNLSD-----HSPYKPDFLRVNQPNFYMHYFSCFGCAYLAPERLI
.... ..      ..  .   . ||... .  .||| | |  .||||.||..  .. ..|     .                  .  |    |.||| | 
YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----------------TTFCGTPWYMAPEVL-

ENESSPNIDMYASDYFSLGCVLYYIFTDGNHLFDFGTLVQYKNGEKDFTEKVNKVTDPNMRKLIELLISIDTKDRFSAMQNYQ--------SYF
        .  ..|  |.||.||  .. |  .|.    . .|.             .| .. .|. .   | ..| .| .  |         .|
------GYGKCKCDWWSCGCILYEMLC-GYPPFP-QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84085.m00082.AA VPS15 222-300 30 4.4e-11 34.7 In-house 218-296 (296) Show / Hide 
Range on Protein: 222-300
Range on HMM: 218-296/296
Sequence Identity: 30% (25 aa)

DYFSLGCVLYYIFTDG-NHLFDFGTLVQYKNGE-KDFTEKV-NKVTDPNMRKLIELLISID-TKDRFSAMQNYQSYFPQWMSI
| ||.|||.  .|..| . .||.  |  |..||  .. |.. .|  |.. | |.  .| .|    | |. .    |  .| ..
DIFSAGCVIAELFCEGDQPPFDYSQLCKYRSGEYHPNREQIMEKIQDEHIRNLCHHMIQKDNPMKRMSCEE----YLNKWRGF
Kinase 84085.m00082.AA C8 135-230 28 9.1e-09 26.68 In-house 128-226 (226) Show / Hide 
Range on Protein: 135-230
Range on HMM: 128-226/226
Sequence Identity: 28% (29 aa)

ISYQLVRSVFSLHSHEIYHGAIKPENVL----LSDRFEVNLSDHSPYKPDFLRVNQPNFYMHY-FSCFGCAYLAPERLIENESSPNIDMYASDYFSLGCV
|  |.. .|  .|...| |  |||.| |     .  ||. |.|      .... |.  .. .  ..|   ||.||| . ...    .    || ||.| |
IAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFG--FASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLV

L
|
L
Kinase 84085.m00082.AA CMGC 107-169 22 1e-08 23.82 In-house 131-223 (513) Show / Hide 
Range on Protein: 107-169
Range on HMM: 131-223/513
Sequence Identity: 22% (21 aa)

YLVRPYMPLDLVSRMDDFPK----------------------------LTFYDQLWISYQLVRSVF--SLHSHE--IYHGAIKPENVLLSDRFEV
|||  ||. ||   ... ..                            ..  .   ..||. |..    .|||   | |  .||||.|.... |.
YLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCEL
Kinase 84085.m00082.AA Ciliate-E2 135-286 14 1.6e-08 25.33 In-house 150-356 (365) Show / Hide 
Range on Protein: 135-286
Range on HMM: 150-356/365
Sequence Identity: 14% (35 aa)

ISYQLVR---------------SVFSLHSHE-IYHGAIKPENVLLSDRFEVNLSDHSPYKPDFLRVNQPNFYMHYFSCFG--------------------
|..|...                . .|||   | |  |||||.|.                               . ||                    
IMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKW

-------------------------CAYLAPERLIENESSPNIDM--------YASDYFSLGCVLYYIFTDGNHLFDFGTLVQYKNGEKDFTEK------
                         ... ...   |. .. ..|         |..|..|||..||.  . |.. |    . | |... || ..      
YMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF-GKPPF----QQQIKQCKIDFPCPEWQKDT

--------VNKVTDPNMRKLIEL----LISIDTKDRFS-A
         .|  ....  ||      ..  | . |.. .
QCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGW
Kinase 84085.m00082.AA Ciliate-E4 135-173 28 2e-08 24.7 In-house 112-150 (150) Show / Hide 
Range on Protein: 135-173
Range on HMM: 112-150/150
Sequence Identity: 28% (11 aa)

ISYQLVRSVFSLHSHEIYHGAIKPENVLLSDRFEVNLSD
| .... .   | .  |.|| .|| |..... |.| . |
IAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD
Kinase 84085.m00082.AA Ciliate-E1 135-224 23 4.1e-08 23.0 In-house 114-202 (202) Show / Hide 
Range on Protein: 135-224
Range on HMM: 114-202/202
Sequence Identity: 23% (21 aa)

ISYQLVRSVFSLHSHEIYHGAIKPENVLLSDRFEVNLSDHSPYKPDFLRVNQPNFYMHYFSCFGCAYLAPERLIENESSPNIDMYASDYF
| .||.  .  ||.. |.|. |||.|.| ..  . ...|..  |   .  ||   | .| ... . .   . .  ..  .... | || .
IIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKNQKINYKSDIY
Kinase 84085.m00082.AA Ciliate-C8 142-230 26 4.1e-08 25.53 In-house 131-238 (238) Show / Hide 
Range on Protein: 142-230
Range on HMM: 131-238/238
Sequence Identity: 26% (29 aa)

SVFSLHSHEIYHGAIKPENVLLSDR----FEVNLSD---------HSPYKPDFLRVNQPNFYMHYFS-----CFGCAYLAPERLIENE-SSPNIDMYA--
||  || ..| |  |||.| |...     ... |.|          |  . .  ..   .|   .       |   .| |||  .|.. |  . | .   
SVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPE--VEKKQSRIQSDIFSKK

SDYFSLGCVL
|| .|.| ||
SDSYSVGLVL
Kinase 84085.m00082.AA Ciliate-A5 146-231 28 5.4e-07 20.37 In-house 115-209 (275) Show / Hide 
Range on Protein: 146-231
Range on HMM: 115-209/275
Sequence Identity: 28% (27 aa)

LHSHEIYHGAIKPENVLLSDRFEVNLSDHSPYKPDFLR---VNQPNFYMHYFSCFGCAYLAPERLIENESS-------PNIDMYASDYFSLGCVLY
|.. .|.|| |.| |..|..  .| | |..  | ||.      ....| |  |     ||.|. ..  .         |. . | || |.|| ...
LQQNNICHGDIRPQNICLTQDGQVKLMDMNESK-DFFYQINWSSYKQYQHHMSTENKQYLSPMQWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICL
Kinase 84085.m00082.AA Ciliate-C3 132-174 37 5.9e-07 21.31 In-house 98-140 (140) Show / Hide 
Range on Protein: 132-174
Range on HMM: 98-140/140
Sequence Identity: 37% (16 aa)

QLWISYQLVRSVFSLHSHEIYHGAIKPENVLLSDRFEVNLSDH
.| || |..  .  || | | || ||..|.|.  . |. . | 
KLQISKQILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
Kinase 84085.m00082.AA VPS15 134-182 32 1e-06 19.02 In-house 102-151 (296) Show / Hide 
Range on Protein: 134-182
Range on HMM: 102-151/296
Sequence Identity: 32% (16 aa)

WISYQLVRSVFSLHSHE-IYHGAIKPENVLLSDRFEVNLSDHSPYKPDFL
||  |.   .  .|  . . ||.||.||.|..    . |.|  ..|| .|
WIAFQTLCALEQCHKQGNVCHGDIKSENILVTSWNWCYLTDFACFKPCYL
Kinase 84085.m00082.AA IRE 222-241 60 3e-06 17.35 In-house 214-233 (292) Show / Hide 
Range on Protein: 222-241
Range on HMM: 214-233/292
Sequence Identity: 60% (12 aa)

DYFSLGCVLYYIFTDGNHLF
| ||.|||.||..| |.| |
DIFSMGCVFYYVMTNGQHPF
Kinase 84085.m00082.AA Pkinase 201-294 17 0.0009 14.42 Pfam 177-293 (293) Show / Hide 
Range on Protein: 201-294
Range on HMM: 177-293/293
Sequence Identity: 17% (21 aa)

YLAPERLIENESSPNIDMYASDYFSLGCVLYYIFTDGNHLFDFGT---------LVQYKNGEKDFTEKVNKVTD-------------------PNMRKLI
|.||| .     . . . ...| .|.||.||. .. |. .|. |           . ........ .   .  .                   ......|
YMAPEVIR----GGQYYGPKVDMWSCGCILYEMLC-GRPPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

ELLISIDTKDRFSAMQNYQS-YF
. ..  | |.| .|.|  |. .|
KWCLCKDPKKRPTAEQILQHPWF
Kinase 84085.m00082.AA IRE 146-173 30 0.001156 8.09 In-house 132-167 (292) Show / Hide 
Range on Protein: 146-173
Range on HMM: 132-167/292
Sequence Identity: 30% (11 aa)

LHSHEIYHGAIKPENVLLSD--------RFEVNLSD
|||. | |  .||.|.| ..        . .. .||
LHSQNIVHRDLKPHNILIHMNRPNQHGENNRFMISD
Pkinase 84085.m00082.AA Pkinase 97-173 23 0.284599 5.58 Pfam 66-155 (293) Show / Hide 
Range on Protein: 97-173
Range on HMM: 66-155/293
Sequence Identity: 23% (21 aa)

IQYFVTNNAAYLVRPYMPLDLVSRMDDF--------PKL--TFYDQLWISYQLVRSVFSLHSHEIYHGAIKPENVLLSDRFEV----NLSD
. .| ...  |.| .|.. .|   || |         ..  .  .   . ||..| .  .||. | |  .||||.|.... ..     ..|
YDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICD
WD40 84085.m00082.AA WD40 844-877 16 0.615703 1.69 SMART 1-46 (46) Show / Hide 
Range on Protein: 844-877
Range on HMM: 1-46/46
Sequence Identity: 16% (8 aa)

SANINYPCR------YVTNVKKSPYG-------TFICVCDDN-AFIYD
. .  . ..      .|| |. .| |        ... . |.   |.|
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
WD40 84085.m00082.AA WD40 946-985 18 4e-05 24.26 SMART 1-46 (46) Show / Hide 
Range on Protein: 946-985
Range on HMM: 1-46/46
Sequence Identity: 18% (9 aa)

PEGYTRGLHGHTS--RVTAAWLSDND------DLFVTGDESGVINFWS
.   .. ..|||.  .||.   ....      .....|.  | | .|.
T-KCVHTFKGHTGNSWVTCVCWHPDGGSDDYPNYLASGS-DGTIRIWD
WD40 84085.m00082.AA WD40 947-985 22 8.4e-05 16.44 Pfam 1-39 (39) Show / Hide 
Range on Protein: 947-985
Range on HMM: 1-39/39
Sequence Identity: 22% (9 aa)

EGYTRGLHGHTSRVTAAWLSDN-DDLFVTGDESGVINFWS
   .. . |||. ||.   ...   ....| . | |  |.
WKCKHTF-GHTHWVTCCAWHPDMGHYLASGSRDGTIRIWD