Gene 90925.m00094 (T.vaginalis)

90925.m00094

Species: T.vaginalis
Alias: TvagK0599, 90925.m00094
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK20

Sequence

Name Sequence Type Origin Length Description Download
90925.m00094.AA Protein None 324 None Fasta, JSON
90925.m00094.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of 90925.m00094.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90925.m00094.AA CDK 54-300 33 1e-93 300.18 In-house 57-284 (284) Show / Hide 
Range on Protein: 54-300
Range on HMM: 57-284/284
Sequence Identity: 33% (90 aa)

REIQALSVASHPNIVKLHEVVQVQ-----------PSISLVMEYLPYTLSQVVQLSILPEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGI-
|||  |    ||||||||.|.               ....|.||... |...          .| .|..|||||...|. .|.|||.||.|.|.| .|. 
REISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD--------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEV

----LKICDLGLCRILPEKLAGIGGVKTDDD-THAWTLQVGTSFYRAPELLLGDRGYG--EAVDTWAVGCVMAELLN---GKPLFNGQGDIEQLGFISGI
    ||| | || |.    .       .. . . . | .| |  |||||||||.. |.   ..| |.|||..||...   .|||| |. .|.||  |. |
KCGRLKIADFGLARAFGIPHQ------MS-EPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRI

LGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSPEAVDLFKQFIVYEPGQRISARNAMKHKWF
.|.|... |||...||.                          ||  .. .|.| .||||  |..|..|
CGTPTEDNWPGVTKLPDY-------------------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 90925.m00094.AA CMGC 8-300 21 1.8e-90 297.47 In-house 1-513 (513) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

YGNLTLIGEGRFSFVYKTQN--------------QMNSHLYAVKVMSPNSKIPEPSV----------AFYREIQALSVAS-----------------HPN
| ..  |||| .. ||| ..                .  ..|.| .. .   .|               .|||. |   .                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKLHEVVQVQP-----------------SISLVMEYLPYTLSQVVQ----------LSILPEAI------------VKGIM------LMLLRGLA--HL
||||.....                    .. ||.||....| |. .             |.|              .| .|       ..||||.  ..
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HELG--IIHRDIKPANLLMNPQ--------------------GILKICDLGLCRILPEKLAGIGGVKTD---------DDTHAWTLQVGTSFYRAPELLL
|  .  |||||.||.|.|.|..                    |.||||| ||.|.. .    ... ..          . ... | .| | .|||||.||
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GD---------RGYGEAVDTWAVGCVMAELLNG--------KPLFN-----------GQGDIEQLGFISGILGSPD---------------DKKWPGFSQ
|.         ..|....| |.|||..||...|        ||||            |. .|.||  |  .||.|.               ...||....
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

LPGSGQIL-------------------------FKEREPANIAELFPAWS-----------------------------------PEAVDLFKQFIVYEP
||.  . .                         |... | .. .|||  .                                   |.|.|| |.  .|.|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

GQRISARNAMKHKWF
 .||.|  |..| .|
DKRITAEQALQHPYF
Kinase 90925.m00094.AA S_TKc 8-300 27 2.3e-86 294.14 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-231/231
Sequence Identity: 27% (87 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSKIPEPSVAFYREIQALSVASHPNIVKLHEVVQVQPSISLVMEYLPY---TLSQVVQLSI-----
|  | .||.| |. ||| ..    ...|.|...           ..|||| |.   |||||||..| |   .. .||||..    .| .. .        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCRILPEKLAGIGGVKTDDDTHAWTLQVGTSFYRAPELLLGDRGYGE-A
  .||  .. .|  ....|...|..||||||.||.|.|..    .|||| ||.|.|                   | ..|| .|.|||.|    |||  .
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------------TTFCGTPWYMAPEVL----GYGKCK

VDTWAVGCVMAELLNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSPEAVDLFKQFIVYEPGQRISARNAMK
.| |..||...|.| |.|.|       |.  .  ..|                                    |||| |. ..  ...| .|..|  |..
CDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQ

-------HKWF
       | ||
DEWDIKCHPWF
Kinase 90925.m00094.AA CDK7 54-300 35 1.3e-77 206.17 In-house 51-288 (288) Show / Hide 
Range on Protein: 54-300
Range on HMM: 51-288/288
Sequence Identity: 35% (89 aa)

REIQALSVASHPNIVKLHEVVQVQPSISLVMEYLPYTLSQVVQLS--ILPEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCR
|||  |   .|.|.. |  .   . .|.||.....  |  |.  .  ||  | .| .|.|.|.|| ..|   | |||.|| |||||. |.||| | || |
REIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIKDKSIILTPAHIKAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLAR

ILPEKLAGIGGVKTDDDTHAWTLQVGTSFYRAPELLLGDRGYGEAVDTWAVGCVMAELLNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSGQ
  .                ..| || | .||||||| | | || .|| |.|||..|||.   | . |..|| ||  |  .|| | ...||. ....    
FYGS------------PNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAELMLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMM--DY

ILFKEREP---ANIAELFPAWSPEAVDLFKQFIVYEPGQRISARNAMKHKWF
| ||.  .       ..| | | ...|| .     .| .|.... . |.. |
IKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 90925.m00094.AA Pkinase 8-300 29 1.2e-76 265.79 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-293/293
Sequence Identity: 29% (93 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSKIPEPSVAFYR--EIQALSVASHPNIVKLHEVVQVQPSISLVMEYLPYTLSQVVQLS-------
|  .  ||.| |. ||| ... .....|||...  .. ..  ..  |  ||| .   .|||||.|.....  ..| .||||.. .|. |  |.       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

--IL--PEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGIL----KICDLGLCRILPEKLAGIGGVKTDDDTHAWTLQVGTSFYRAPELLLGD
   .  .|  .| .|. .||||...|. ||||||.||.|.|.. .| .    |||| ||.. .           .  .. ..|. .||..|.|||...|.
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------Y-NNS-MTTF-CGTPWYMAPEVIRGG

RGYGEAVDTWAVGCVMAELLNGKPLFNGQ----GDIEQLGFISGILGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSPEAVDLFKQFIVYEPG
..|| .|| |..||...|.|.|.|.| |.    . ..|.  |  |.| | .  ||  .  . .  . . . .     .. ..||.|. |. |  . . | 
QYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-F-HWTF-HNWSEECKDFIKWCLCKDPK

QRISARNAMKHKWF
.|..|. ...|.||
KRPTAEQILQHPWF
Kinase 90925.m00094.AA CCRK 8-300 42 1.1e-74 254.42 In-house 1-285 (285) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-285/285
Sequence Identity: 42% (126 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSKIPE--PSVAFYREIQALS-VASHPNIVKLHEVVQVQPSISLVMEYLPYTLSQVVQLSILP--E
|  |  ||||    |.| .      . |.| . .  .. .  |  |  |||.||  .     .|.| .|        || |..   |. ||  .  |  |
YCILDRIGEGAHGIVFKAKHVETGEIVALKKV-ALRRLDDGIPNQAL-REIKALQEIEDNQYVVQLKDVFPHGTGFVLVFEFMLSDLAEVVRHAQRPLAE

AIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCRILPEKLAGIGGVKTDDDTHAWTLQVGTSFYRAPELLLGDRGYGEAVDTWAV
| ||  |.|||.|.|| ||  |.|||.||||||.   | ||| | || |.             .|.   .| || | .||||||| | | | . || |||
AQVKSYMQMLLKGVAHCHENNIMHRDLKPANLLISESGHLKIADFGLARVF-----------SNDEGRQYTHQVATRWYRAPELLYGARQYDQGVDLWAV

GCVMAELLNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSPEAVDLFKQFIVYEPGQRISARNAMKHKWF
||.| ||||. |.| |. ||||| ..  ||| | .| ||.. .||   .| |||. |  . .. |  ||.|.|| |||.|| | |||.| .|. |..|
GCIMGELLNNSPIFPGENDIEQLCCVLRILGTPTPKVWPEMKDLPDYNKISFKEQPPMPLEQVVPDASPQALDLLKQFLVYPPRQRIAASQALLHQYF
Kinase 90925.m00094.AA CDC2 8-300 33 2.3e-70 215.28 In-house 1-301 (301) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-301/301
Sequence Identity: 33% (107 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSKIPE---PSVAFYREIQALSVAS-HPNIVKLHEVVQVQPSISLVMEYLPYTLSQVVQ----L-S
|  .  |||| .  ||| ...    . |.|     .   .   || |  |||  |     ||||||||.|.    .. .| ||| . | .         .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAI-REISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNK

ILPEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCRILPEKLAGIG-GVKTDDDTHAWTLQVGTSFYRAPELLLGDRGYGEAV
 .|...|| .|  .|.|....|  .|.|||.|| |.| . .| .|| | || |  .  .  .  .             | |  |||||.|||.. |  .|
HMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTE-----------HEVVTLWYRAPEILLGCKRYSTPV

DTWAVGCVMAEL---LNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPA---------WSPEAVDLFKQFIVYEP
| |..||..||.    . |||| |.  |.||  |  |||.|....||| .|||   .  | . .| .. ...|            ||..|| .| ..|.|
DMWSIGCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNT-FPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDP

GQRISARNAMKHKWF
 .||||. |..|..|
QKRISAKEALQHPYF
Kinase 90925.m00094.AA CDK5 8-300 33 2.9e-64 201.79 In-house 1-287 (287) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-287/287
Sequence Identity: 33% (101 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSK-IPEPSVAFYREIQALSVASHPNIVKLHEVVQVQPSISLVMEYLPYTLSQVVQ--LSILPEAI
|  .  |||| .  ||| .|.    ..| |    .|     || |  |||  |    |.||| || |.     . || |..   |          .  .|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAI-REICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHI

VKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCRILPEKLAGIGGVKTDDDTHAWTLQVGTSFYRAPELLLGDRGYGEAVDTWAVGC
.| .|. ||.|||  ||  . ||| || ||| | .|.||  | || |       ||  |..      ..  | |  ||.|  |.| . |   .| | .||
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAF-----GI-PVRC------YSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGC

VMAELL-NGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSG--QILFKEREPAN-IAELFPAWSPEAVDLFKQFIVYEPGQRISARNAMKHKWF
..||.  .|.||| | .. .||  |  |.|.|   |||. ..||        .  ...    ... |  . .  || .. ....| ||||| .|..| .|
IFAEMANAGRPLFPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 90925.m00094.AA CDK-Unclassified 8-300 28 2e-62 204.09 In-house 1-324 (324) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-324/324
Sequence Identity: 28% (95 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSKIP----------EPSVAFYREIQALSVASHPNIVKLHEVVQVQPSIS-------------LVM
|  .  .||| |  |.|   .  .   | |  . | |            .  .   |||  |    | || |. ...      |             .||
YRMQCKYGEGTFGCVCKAIDFQTQKHVAIKKIMVNNKKGNKCKHILPLLNSKITDQREISCLQNCNHMNIIKFMDMHYDHDRCSKNPYYDNLHPSFYMVM

EYLPYTL-----SQVVQLSILPEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQG-----ILKICDLGLCRILP---EKLAGIGGVKTDDDTHA
|| |||.     . .  ||      ..  |. .| |.| ||. .|.||||||.|..   ..     .||| | |. .        |   .. . ..    
EYMPYTWYNQLHNNRYNLSM---CQIRNFMHQMLEGIAYLHCNKIMHRDIKPQNIMITNNNSTVSPMLKIADFGQACFYMNCPPNLNYQTPADPMQ---Q

WTLQVGTSFYRAPELLLGDRGYGEAVDTWAVGCVMAELLNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSP
 . || |  |||||||.|.. |. .|| |..||..||.. |||.| |. .|||.. |...||.| .  ||  ...|. . |.||  .. .  ..||  . 
YSTQVSTRWYRAPELLFGSKCYDTGVDIWSFGCIYAEWFQGKPIFQGRTEIEQMHHIFKMLGTPCEDMWPDWRYMPDYCKIFFKYKQKFHWWNRFPKCKH

EA-VDLFKQFIVYEPGQRISARNAMKHKWF
.   ..  |  .| |  | ..  . .| ||
ASENNCEFQMVMYQPYNRWKCMEILQHPWF
Kinase 90925.m00094.AA PITSLRE 54-300 37 3.3e-62 212.97 In-house 49-295 (295) Show / Hide 
Range on Protein: 54-300
Range on HMM: 49-295/295
Sequence Identity: 37% (98 aa)

REIQALSVA-SHPNIVKLHEVV--QVQPSISLVMEYLPYTLSQVVQLSI-----LPEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKIC
|||. .  |  |||||.. |.|      .| .||||.   |  .            .  .|  |. |||| .|.| . |.||| | .|||.. .||||||
REINMILMALQHPNIVNVKEIVMGSNMDKIYMVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKIC

DLGLCRILPEKLAGIGGVKTDDDTHAWTLQVGTSFYRAPELLLGDRGYGEAVDTWAVGCVMAELLNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQ
| || |   .               . |. | |  ||||||||| . |  .|| | |||..||.. .||||.|...|.|.  |   .| |  | |||.. 
DFGLAREYGSP------------IKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSEIDQINCIFKEMGTPTEKIWPGWTE

LPGSGQIL-FKEREPANIAELFP---AWSPEAVDLFKQFIVYEPGQRISARNAMKHKWF
||..  .  |..  . |  ..||     |  . ||  |.  | | .||.|  |.|| ||
LPHWKMMNNFPHYPYNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASDALKHPWF
Kinase 90925.m00094.AA CDK10 8-300 35 4.7e-59 202.51 In-house 1-285 (285) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-285/285
Sequence Identity: 35% (106 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSKIPEPSVAFYREIQALSVASHPNIVKLHEVV--QVQPSISLVMEYLPYTLSQVVQLSILP--EA
.  |  .||| .  ||.        . |.| .  .       ..  |||. |    |.|||.|||||  |   || |||.|    |  ...    |  |.
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMPQPFTET

IVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCRILPEKLAGIGGVKTDDDTHAWTLQVGTSFYRAPELLLGDRGYGEAVDTWAVG
 || ||| .||||  ||.  .||||.| .||||  .| .|. | || |        .            | .. | .||||||||| |    |.| ||||
QVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPM------------TPKMVTLWYRAPELLLGCRTQTTAIDMWAVG

CVMAELLNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSPEAVDLFKQFIVYEPGQRISARNAMKHKWF
|...||| .|||. |. .| |.  |  .||.|... |||||.||  ..   |.    |. . |.  |     | .  ..|.| .|  | .... ..|
CILGELLVHKPLMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTLKKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase 90925.m00094.AA RCK 176-300 35 8.3e-37 114.11 In-house 174-298 (298) Show / Hide 
Range on Protein: 176-300
Range on HMM: 174-298/298
Sequence Identity: 35% (44 aa)

VGTSFYRAPELLLGDRGYGEAVDTWAVGCVMAELLNGKPLFNGQGDIEQLGFISGILGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSPEAVD
|.|  |||||.|| .  | . .| |||||.|.||   .|||.|.  | |.  |  ..|.|. | || ...|  . .. |   .. .. .|.|  |.....
VSTRWYRAPECLLRCTYYNSPMDIWAVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCKGMPLKQLIPNCSQDCIE

LFKQFIVYEPGQRISARNAMKHKWF
| .    . |  ||.|  | .|. |
LMEKMLQWDPQKRITAQQALQHPYF
Kinase 90925.m00094.AA RCK 54-151 37 6e-28 85.54 In-house 46-162 (298) Show / Hide 
Range on Protein: 54-151
Range on HMM: 46-162/298
Sequence Identity: 37% (44 aa)

REIQALSVAS-HPNIVKLHEVVQVQP--SISLVMEYLPYTLSQVVQL-----SILPEAI--VKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNP-----
|||..| . . ||||.||.||.....  . ..|.||.   |.|  .        |||    .| ||  .| ||||.|. |. |||.|| |.. ..     
REIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYF

----QGILKICDLGLCR
    |...||.| ||||
EDQDQDHIKIADFGLCR
Kinase 90925.m00094.AA TyrKc 8-300 21 3.1e-13 -8.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-300
Range on HMM: 1-280/280
Sequence Identity: 21% (70 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVMSPNSKIPEPSVAFYREIQALSVA--SHPNIVKLHEVVQVQ-------PSISLVMEYLPY-TLSQVVQL
   .  .||| |  ||| .        |||.. ...       .|.||.. ..    .|||||.|. |.  |       . . .|||| |.  | .  . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

SI--LPEAIVKGIMLMLLRGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCRILPEK-LAGIGGVKTDDDT-----HAWT-LQVGTSFYRAPELLL
.   |. .    ...   .| ..||. ..||||.   | | . ... ||.| ||.| . ..  .|   . .|  .     .. | | .      ||| . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG---ESKDYYRKKEHKGGKTMLPI---RWMAPECI-

GDRG-YGEAVDTWAVGCVMAELL-NGKPLFNG-----QGDIEQLGFISGI--LGSPDDKKWPGFSQLPGSGQILFKEREPANIAELFPAWSPEAVDLFKQ
 . | . .. | |. | .| |.. .|..   |       ..| . ..     .  |..   |  |                     |.  ..|  .. ||
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS---------------------FVCCPDEMYQIMKQ

FIVYEPGQRISARNAMKHKWF
   ..| .| . ..   |. |
CWHEDPEDRPTFSEI--HECF
Kinase 90925.m00094.AA Pkinase_Tyr 35-89 31 2e-07 25.78 Pfam 32-91 (270) Show / Hide 
Range on Protein: 35-89
Range on HMM: 32-91/270
Sequence Identity: 31% (19 aa)

AVKVMSPNSKIPE-PSVAFYREIQALSVA-SHPNIVKLHEVVQ-VQPS--ISLVMEYLPY
|||.. ...  ..  . .| ||.. ..   .|||||.|. |.   . .  | .|||| |.
AVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH
Kinase 90925.m00094.AA CDK7 8-37 36 3.5e-05 9.27 In-house 1-30 (288) Show / Hide 
Range on Protein: 8-37
Range on HMM: 1-30/288
Sequence Identity: 36% (11 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVK
|  . .|||| |  ||| . .      |.|
YEKIKHIGEGQFATVYKACDHQTGQIVAIK
Kinase 90925.m00094.AA Pkinase_Tyr 114-151 39 0.00479 10.94 Pfam 122-159 (270) Show / Hide 
Range on Protein: 114-151
Range on HMM: 122-159/270
Sequence Identity: 39% (15 aa)

RGLAHLHELGIIHRDIKPANLLMNPQGILKICDLGLCR
.|...|.. ..||||.   | | . ... |||| ||.|
KGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase 90925.m00094.AA RCK 8-39 31 0.019012 3.25 In-house 1-32 (298) Show / Hide 
Range on Protein: 8-39
Range on HMM: 1-32/298
Sequence Identity: 31% (10 aa)

YGNLTLIGEGRFSFVYKTQNQMNSHLYAVKVM
|  .. .|.| .. | | ||  .  ..| | |
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKM
Kinase 90925.m00094.AA CDK 8-37 31 0.048319 2.14 In-house 1-35 (284) Show / Hide 
Range on Protein: 8-37
Range on HMM: 1-35/284
Sequence Identity: 31% (11 aa)

YGNLTLIGEGRFSFVYKTQNQMNS-----HLYAVK
|  |  |||| .  ||| ... .      ...| |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALK