Gene 93440.m00433 (T.vaginalis)
93440.m00433
Species: T.vaginalis
Alias: TvagK0497, 93440.m00433
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
93440.m00433.AA | Protein | None | 592 | None | Fasta, JSON |
93440.m00433.kin_dom | Protein Kinase Domain | None | 230 | None | Fasta, JSON |
Protein domains of 93440.m00433.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 93440.m00433.AA | CK1-Unclassified | 9-241 | 51 | 2.7e-155 | 461.74 | In-house | 1-244 (244) | Show / Hide |
Range on Protein: 9-241 Range on HMM: 1-244/244 Sequence Identity: 51% (125 aa) YILQQKIGQGSFGQIYIAIDKDTGERYAVKVEDNNVSVPQLLFEARIYQIMAGST-------NIPRLFYQAED--FDRNVIVIELLGNSLEGLLTKCNRH | . .||||||||.|| .|...|.| .|.|.|..|. |||..||.|.|.. . .||.... . . | |..| .||| ||| |. .||| YRVIEKIGQGSFGEIYKCINMQTNEEVAIKLEKKNSKHPQLCYEAKIMQYLQNGHNCDNFIKGIPKMYWCGQEEQGDYNIMVMDLLGPSLEDLFNMCNRK MSVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMG-KGNCANKLYIIDYGLAKRYRDQ-NTHQHIKFSSGKSLTGTARYASINALAGYEQSRRDDIE |.||| |.|.|||. ....|.||.||||.|||||.|| |. ....||||.||.|||.| .|..|| . .|.|||||||||||| |.||||||| | FSLKTVLMIADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKHIPYRENKNLTGTARYASINAHLGIEQSRRDDLE GLAYVLIYLCKGSLPWMGIDAKDRKEKYAKICESKRKTSPEVLC |.|||||. ||||||..| |...|||| || | | |..| || SLGYVLIYFLKGSLPWQNIKANNKKEKYEKIMEMKMSTPVEQLC |
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Kinase | 93440.m00433.AA | CK1 | 9-267 | 51 | 7e-153 | 514.2 | In-house | 1-271 (271) | Show / Hide |
Range on Protein: 9-267 Range on HMM: 1-271/271 Sequence Identity: 51% (139 aa) YILQQKIGQGSFGQIYIAIDKDTGER--YAVKVEDNNVSVPQLLFEARIYQIMAG------STNIPRLFYQAED--FDRNVIVIELLGNSLEGLLTKCNR | . .||||||||.|| .|. ..||. .|.|.|.|. |||..||.||.|. | . .||.. . . . | |..|..||| ||| |. .||| YRVGRKIGQGSFGDIYLGINMTNGEENHVAIKLEKNKSKHPQLHYEAKIYKILQGHNCDNQCHGIPHMYWCGQEEQGDYNIMVMDLLGPSLEDLFNFCNR HMSVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGK-GNCANKLYIIDYGLAKRYRDQNTHQHIKFSSGKSLTGTARYASINALAGYEQSRRDDIE . |.|||.|.|.|||. ....|.||.||||.|||||.|| |. ....||||.|||||||| .||||| . .|.|||||||||||. |.||||||| | KFSLKTVLMIADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDME GLAYVLIYLCKGSLPWMGIDAKDRKEKYAKICESKRKTSPEVLCQG-LPSVFAQFLVMARGLSFEQEPDYV |.|||.|...|||||.|. |. .|.|| ||.| |..|..|.||.| .|. ||..| .|.|.||..||| SLGYVLMYFLRGSLPWQGLKANTKKQKYEKIMEKKMSTPVEQLCKGNFPNEFAMYLNYCRQLHFEEKPDYM |
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Kinase | 93440.m00433.AA | CK1-D | 9-269 | 50 | 4.4e-117 | 395.28 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 9-269 Range on HMM: 1-261/261 Sequence Identity: 50% (132 aa) YILQQKIGQGSFGQIYIAIDKDTGERYAVKVEDNNVSVPQLLFEARIYQIMAGSTNIPRLFYQAEDFDRNVIVIELLGNSLEGLLTKCNRHMSVKTVCML | . ||| ||||.|| . |.| |.|.| ||| .|...|..| | ||.. . .. | ||.|..||| ||| | |.|. |.||| || YRIGRKIGSGSFGDIYHGTNIQTNEEVAIKLECIKTKHPQLHIESKFYKMMQGGIGIPEIRWCGQEGDYNVMVMDLLGPSLEDLFNYCHRKFSLKTVLML AEQMITSVQFFHSKNYIHRDLKPDNFVMGKGNCANKLYIIDYGLAKRYRDQNTHQHIKFSSGKSLTGTARYASINALAGYEQSRRDDIEGLAYVLIYLCK |.|||. ... |..|.||||.|||||.|| | | ||||.|||||||| .||||| . |.||||||||||| | |||||||.| | |||.| .. ADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTHQGIEQSRRDDLESLGYVLMYFNR GSLPWMGIDAKDRKEKYAKICESKRKTSPEVLCQGLPSVFAQFLVMARGLSFEQEPDYVTY ||||| |. | ...|| .||| | .|. ..||.|.|| |.|.. .| | |.. |||. GSLPWQGLKAATKRQKYERICEKKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL |
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Kinase | 93440.m00433.AA | CK1-A | 9-269 | 50 | 2.7e-114 | 386.01 | In-house | 1-261 (261) | Show / Hide |
Range on Protein: 9-269 Range on HMM: 1-261/261 Sequence Identity: 50% (133 aa) YILQQKIGQGSFGQIYIAIDKDTGERYAVKVEDNNVSVPQLLFEARIYQIMAGSTNIPRLFYQAEDFDRNVIVIELLGNSLEGLLTKCNRHMSVKTVCML | | .||| |||| ||..| || |.|.| |.. |||..||..|.|..| ||.. . .. | ||.|..||| ||| | |.|. ..||| || YRLVRKIGSGSFGDIYLGINITNGEEVAIKMESNKARHPQLIYEAKVYRILQGCVGIPHMRWYGCEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLML AEQMITSVQFFHSKNYIHRDLKPDNFVMGKGNCANKLYIIDYGLAKRYRDQNTHQHIKFSSGKSLTGTARYASINALAGYEQSRRDDIEGLAYVLIYLCK |.|||. . . | ||.||||.|||||.|| | |||..||.||||.|||..|.|||.. | |||||||||||| | |||||||.| ..||..| . ADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESMGYVMMYFNR GSLPWMGIDAKDRKEKYAKICESKRKTSPEVLCQGLPSVFAQFLVMARGLSFEQEPDYVTY |.||| |. |. .| || || | | |. |.||.| |. |. .. .|.| ||..|||. GKLPWQGMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL |
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Kinase | 93440.m00433.AA | CK1 | 9-269 | 30 | 8.20000000001e-106 | 357.84 | In-house | 1-339 (339) | Show / Hide |
Range on Protein: 9-269 Range on HMM: 1-339/339 Sequence Identity: 30% (106 aa) YILQQKIGQGSFG-QIYIA-----IDKDTG-----ERYAVKVEDNNVS--VPQLLFEARIYQI--------------------MAGSTNIPRLFYQAEDF . . .|||.|.|| ||| . .|.... |.||.||| .. .|||. |...|.. . |. .... | |. WKVVKKIGEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKVEPKKSMGQHPQLMEEYQMYKKLQGGKKWKASILKHKHFCKKHCGCPHPCMYWYHGEED DRN-VIVIELLGNSLEGLLT---KCNRHMSVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGK------GNCAN--------KLYIIDYGLAK-RY |.. ..|..||| .|| |. |||..|.||. |.|.||. .... |....||||.|||||.|| |. . ..|.||.|.|. .| DYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKH-HHEWNNEHRQVYMIDFGMARRKY RDQ-----------NTHQHIKFSS---GKSLTG-TARYASINALAGYEQSRRDDIEGLAYVLIYLCKGS--LPWMGIDAKDR-------KEKYAKICESK || .|.||. . . |...| ||||.|||. | ||.||||.. ..|.||.. ||. |||........ |.||..| | | RDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCHLGKEQGRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKK RKTSPEVLCQG-----LPSVFAQFLVMARGLSFEQEPDYVTY .|... || . .|. | ... . |.|... .||| MSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI |
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Kinase | 93440.m00433.AA | CK1-G | 9-269 | 45 | 4.9e-97 | 328.68 | In-house | 1-266 (266) | Show / Hide |
Range on Protein: 9-269 Range on HMM: 1-266/266 Sequence Identity: 45% (120 aa) YILQQKIGQGSFGQIYIAIDKDTGERYAVKVEDNNVSVPQLLFEARIYQIMAGST-NIPRLFYQAEDFDRNVIVIELLGNSLEGLLTKCNRHMSVKTVCM | ||| |.|| .. ..| |.| | ||| | | |.|..| .||. .| |..|..||| ||| | |.|. ||||||| YRVGKKIGCGNFGELFEGKNMYNNEHVAIKFEPMKSRAPQLHDEYRFYKILNGCPEGIPQVYYFGQCGKYNIMVMDLLGPSLEDLFDWCDRKFSVKTVCM LAEQMITSVQFFHSKNYIHRDLKPDNFVMGK--GNCANKLYIIDYGLAKRYRDQNTHQHIKFSSGKSLTGTARYASINALAGYEQSRRDDIEGLAYVLIY .| |||. .. ||.. | || ||||| |. . .....|||.|.|| |.| .| ||| . ||||||||| ||| | |||||||.| | . .| VAIQMIHRMEYVHSHHLIYRDVKPDNFLIGRPSNKDQHVIHIIDFGMAKQYIDPETKQHIPYREHKSLTGTARYMSINTHLGREQSRRDDMEALGHMFMY LCKGSLPWMGIDAKDRKEKYAKICESKRKTSPEVLCQG--LPSVFAQFLVMARGLSFEQEPDYVTY ||||| | | ||.| || . |||| .|.|||. .| ||..| .| |.|. .||| FLRGSLPWQGLKADNNKERYQKIGDTKRKTNIEDLCQNNAFPEQFATYLRYVRRLDFFECPDYDYL |
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Kinase | 93440.m00433.AA | Worm6 | 9-269 | 24 | 1.5e-48 | 167.64 | In-house | 1-279 (279) | Show / Hide |
Range on Protein: 9-269 Range on HMM: 1-279/279 Sequence Identity: 24% (69 aa) YILQQKIGQGSFGQIYIAIDKDTGE--RYAVKVED--NNVSVPQLLFEARIYQIMAGST--NIPRLFYQAEDFDR--NVIVIELLGNSLEGLLTKC-NRH . . .|||.|.|| .| . ||.... ..|.|.| | . ..| .|. . . . . . .... .. . | | ||..|.| .|. | . .|. WKVTKKIGEGGFGAVYKVEDKSDKKKKQFAMKCEKQMENMKRQMLKMECMVLKAVKHHKCRHFCKIEDRGKVDNRGFNYIVMTLVGKNLWDLRKNRPDRK MSVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGK-----GNCANKLYIIDYGLAK--RYRDQNT-HQHIKFSSGKSLTGTARYASINALAGYEQS .|. | .|.|.. ... |. .||||.|| || | | ..|..|.|... .|..... .. . . || |||.... | ||. FSMGTGLKIAIQCLEAIEDLHNCGFIHRDVKPGNFCIGRYQMKEDNEHHTIYMLDFGMCRRKKYCNKGNELRTPRWTACG-FRGTVRYAPLACHKGQEQC RRDDIEGLAYVLIYLCKGSLPWMGIDAKDRKE-KYAKICESKRKTSPEVLCQGLPS-VFAQFLVMARGLSFEQEPDYVTY |.||.|. |... . .| |||......|..| . ... .|.. . . .. | | . . ..|.. .||| . RKDDCESWFYMMVEMIVGCLPWRHMKDHDHVEKHKKWCRRRTRAPMMRMFFGPCPKEEFNDIMDYIDQYSYWDRPDYKFI |
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Kinase | 93440.m00433.AA | TTBKL | 9-273 | 25 | 1.5e-45 | 151.75 | In-house | 1-288 (288) | Show / Hide |
Range on Protein: 9-273 Range on HMM: 1-288/288 Sequence Identity: 25% (76 aa) YILQQKIGQGSFGQIYIAIDKDT-GERYAVKVEDNNVSVPQ--LLFEARIYQIMA--GSTNIPRLFYQAEDFDRNVIVIELLGNSLEGLL-TKCNRH-MS . ...||.| |||.| ..|. . ....|.|.| | . . .|. . .. ||. .|.. .. . | | .| .|.| .| | . .|.. .| WMIVKMIGEGGFGQVYHVWDMKDKKDCAAMKEEKNRLEGGDSRMKMEVHVLMKLQPNGSPHFPKCHCSGKRKDYNFMVMTLCGPNLQDLRKMMPNKKRFS VKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGKGNC----ANKLYIIDYGLAKRYR----------DQNTHQHIKFSS---GKSLTGTARYASINA . |. .. | . ... |.. .||||.|| |...| . .|.||.|.|..|. .|. .. . . .. || ||.|.|. DGTWSRIGIQCLYALKQMHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGEWNGPIHENKWMMRRPRNFRHKAPFRGTTRYCSPNM LAGYEQSRRDDIEGLAYVLIYLCKGSLPWMGIDAKDRKEKYAKICESKRKTSPEVLCQG------LPSVFAQFLVMARGLSFEQEPDYVTYRSLF ...||.| ||. . |..|.| .| ||| ... |.. |. |.... |.|... .|| |. | . | |.. ..||| . .| HDRKEQGRHDDLWSWMYMIIELHCG-LPWTNMEDKMEIEHM------KKNMKDEDLFKDMPRDHDCPSEFCKFMKHLRSLRYYDRPDYEMIYECF |
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Kinase | 93440.m00433.AA | Pkinase | 9-228 | 24 | 8.1e-37 | 131.27 | Pfam | 1-230 (293) | Show / Hide |
Range on Protein: 9-228 Range on HMM: 1-230/293 Sequence Identity: 24% (58 aa) YILQQKIGQGSFGQIYIAIDKDTGERYAVKVEDNNVSVP----QLLF--EARIYQIMAGSTNIPRLFYQAEDFDRNVIVIELLGN-----SLEGLLT-KC | . .|||.||||. |....|.||...|||. . . ... |..| . . .. || ||.. || |. .| |.... .| ... . YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR NRHM--SVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMG-KGNCANKLYIIDYGLAKRYRDQNTHQHIKFSSGKSLTGTARYASINALA-GYEQSR .. . | ..... . |.. ... ||.. |||||||.|. . .|... .. |.| |||| .. . . | ....|| .|.. . | . .. HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP RDDIEGLAYVLIYLCKGSLPWMGI----DAKDRKEKYAKI . |. .. .|.... | .|. | . | ......| KVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRI |
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Kinase | 93440.m00433.AA | TTBK | 78-269 | 34 | 1.4e-27 | 94.54 | In-house | 71-257 (257) | Show / Hide |
Range on Protein: 78-269 Range on HMM: 71-257/257 Sequence Identity: 34% (68 aa) NVIVIELLGNSLEGLLTKCNRHM-SVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGK-GNCANKLYIIDYGLAKRYRDQNTHQHIKFS-SGKSLT | .| .|.| .| | | | |. | | |.. |.. || . ||| || || ||. .| |..|.||| .| |.. . . NYMVMQLQGKNLADLRRKQPRGCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQY--TNACGEVRPPREVAGFR GTARYASINALAGYEQSRRDDIEGLAYVLIYLCKGSLPWMGIDAKDRKEKYAKICESKRKTSPEVLCQGLPSVFAQFLVMARGLSFEQEPDYVTY ||.||||||| | |.|| | |.|. .| ||| | || .. | | | .| . .|. | ||. . | .| |||. GTVRYASINAHRNREMGRHDDLWSLFYMLVEFVQGQLPWRKIKDKD------QVGEMKEKYDHRMLLKHCPHEFHQFMDHIKSLNYEDRPDYQLI |
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Kinase | 93440.m00433.AA | S_TKc | 9-291 | 18 | 3.4e-21 | 77.64 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 9-291 Range on HMM: 1-231/231 Sequence Identity: 18% (57 aa) YILQQKIGQGSFGQIYIAIDKDTGERYAVKVEDNNVSVPQLLFEARIYQIMAGSTNIPRLFYQAEDFDRNVIVIELLGN---SLEGLLTKCNRH-----M | . .|||.|.||. | ...|.||...|.|. . ... | .| . . || .|.. .| |. .| |.... .| .. |..|| . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF SVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGKGNCANKLYIIDYGLAKRYRDQNTHQHIKFSSGKSLTGTARYASINALAGYEQSR-RDDIEGL . ... .. |.. ... ||.. |||||||.| . . . |.| |||... ... || | . | .. . |. . PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL--------------TTFCGTPWYMAPEVL---GYGKCKCDWWSC AYVLIYLCKGSLPWMGIDAKDRKEKYAKICESKRKTSPEVLCQGLPSVFAQFLVMARGLSFEQEPDYVTYRSLFRNYFISQNWVYD---------YQ--- .|. .. | |. . .. . ||. . ... ||.. ...| | GCILYEMLCGYPPFP-----QMQMMFKKIG----------------------------------------SPEAKD-FIRKCLQKDPEKRPTAEALQDEW ----YDWS | DIKCHPWF |
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Kinase | 93440.m00433.AA | VRK | 80-214 | 32 | 1.7e-20 | 62.77 | In-house | 106-241 (284) | Show / Hide |
Range on Protein: 80-214 Range on HMM: 106-241/284 Sequence Identity: 32% (45 aa) IVIELLGNSLEGLLT-KCNRHMSVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGK-GNCANKLYIIDYGLAKRYRDQNTHQHIKFSSGKSLTGTA .|.. .| .|. .. .. | ||| || .|. . .. |...| | |.| | |. .| ... | .||||| || . | | . . || MVMPRFGRDLQKIYEDQNGHRFSMKTVLQLACRMLDVLEYLHENEYVHGDIKAANILLGFEKN-PDQVYLVDYGLAYRYCPNGKHRQYKEDPRRCHNGTC RYASINALAGYEQSRRDDIEGLAYVLIYLCKGSLPWM . |. | | ||| |.| |.| ... |.|||| EFTSMDAHKGCAPSRRSDLEILGYCMMMWLYGYLPWM |
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Kinase | 93440.m00433.AA | TTBK | 9-40 | 45 | 4.3e-07 | 21.15 | In-house | 1-33 (257) | Show / Hide |
Range on Protein: 9-40 Range on HMM: 1-33/257 Sequence Identity: 45% (15 aa) YILQQKIGQGSFGQIYIAIDKDTG-ERYAVKVE .|||.| || || | | . |. |.||| WKVVKKIGGGGFGEIYEAKDMINHHEQVAIKVE |
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Kinase | 93440.m00433.AA | TyrKc | 9-244 | 19 | 3e-06 | -121.9 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 9-244 Range on HMM: 1-280/280 Sequence Identity: 19% (56 aa) YILQQKIGQGSFGQIYIAIDKDTGERYAVKVEDNNVSVPQLLFEARIYQIM-AGSTNIPRLFYQAEDF-------DRNVIVIELLGN-SLEGLLTKCNRH | .|.| | ||..| .. | . |||. .. . .. |||| || ||. . . . || |. . .| | |. .. ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK MSVKTVCMLAEQMITSVQFFHSKNYIHRDLKPDNFVMGKGNCANKLYIIDYGLAKRYRDQ----NTHQHIKFSSGKSLT--GTARYASINALAGY----- ..|. . . | .. ||||.||||| | |... | | ||.. | .. .. ...|. | .. .. . LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK -----------------EQSRRDDIE---GLAYVLIYLCKGSLPWMGID--------AKDRKEKYAKIC----ESKRKTSPEVLCQGL .| ..|. . |. |. .| . . . | . | | ..| | |. .. . SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF |
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Kinase | 93440.m00433.AA | VRK | 9-40 | 40 | 0.000184 | 10.69 | In-house | 1-37 (284) | Show / Hide |
Range on Protein: 9-40 Range on HMM: 1-37/284 Sequence Identity: 40% (15 aa) YILQQKIGQGSFGQIYIAID---KDT--GERYAVKVE ..| .|||| || || | . | . . .| ||.| WRLGKPIGQGGFGCIYLASPNTCKPCEKDAQYVVKIE |