Gene 92477.m00178 (T.vaginalis)

92477.m00178

Species: T.vaginalis
Alias: TvagK0751, 92477.m00178
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMK-Tvag2

Sequence

Name Sequence Type Origin Length Description Download
92477.m00178.AA Protein None 347 None Fasta, JSON
92477.m00178.kin_dom Protein Kinase Domain None 270 None Fasta, JSON

Protein domain

Protein domains of 92477.m00178.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 92477.m00178.AA S_TKc 54-323 23 4.1e-55 190.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-231/231
Sequence Identity: 23% (66 aa)

YKFINEIGSGALSRVYQIVSLKDNEILAAKVYDNQRISRPTLTGEDPPYVSIQRELDIMAKLDHRYVISLIDAFNDENTNSLIIIIPFAPL--GNVKTLL
|.....||.|| ..||. .  |...| | |. .                 .|.||..|. | .| ... |.|.| |   ..| ..  ...   |......
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYI

DKRA-------LNSDQLNACFHQVAIALAYMHSMNVVHRDIKPENMLAFTEDYFAITDLSVSQEVESDETMVMDIKGSPAFLSPEECAGTEFIPKPADVW
.||        ..  .    ..|.. ||.|.||....|||.|||| |  .     |.|  .. ..       . . |.| ...|| .    . ....|.|
KKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWW

AYGISLFSCYFGYFPFSIDECDGLPIGNTILMVTEKLNEKELNIPDGTSSDLIDLLTHVLDKDPTKRYTFEQIAN-------HSFF
. |. |. .. || ||.           .. |. .|.           |....|.. . |.|||.||.|  .. .       | .|
SCGCILYEMLCGYPPFP-----------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Pkinase 92477.m00178.AA Pkinase 54-323 20 1.6e-47 169.01 Pfam 1-293 (293) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-293/293
Sequence Identity: 20% (64 aa)

YKFINEIGSGALSRVYQIVSLKDNEILAAKVYDNQRISRPT------LTGEDPPYVSIQRELDIMAKLDHRYVISLIDAFNDENTNSLIIIIPFAPLG--
|...  ||||. ..||. .  ....| | |. . ....         |           .|. ||..|.| ... |.|.| |   ... .. .... |  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----------SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLY

--NVKTLLD---KRAL--NSDQLNACFHQVAIALAYMHSMNVVHRDIKPENMLAFTEDYF----AITDLSVSQEV-ESDETMVMDIKGSPAFLSPEECAG
    ....    ....    ...  .. |.. .|.|.|||...|||.|||| |   ...      |.|  ..  . .   .  ... |.| ...|| . |
VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

TEFIPKPADVWAYGISLFSCYFGYFPFSIDECDGLPIGNTILMVTEKLNEKELNIPDGTS---------------------SDLIDLLTHVLDKDPTKRY
 . .....|.|..|. |.  ..|..||. ..| . .  .. . . ..  ...|  .  ..                     ....|...  |.|||.||.
GQYYGPKVDMWSCGCILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP

TFEQIANHSFF
|.||| .| .|
TAEQILQHPWF
Kinase 92477.m00178.AA CAMK 59-323 17 1.7e-46 147.41 In-house 1-425 (425) Show / Hide 
Range on Protein: 59-323
Range on HMM: 1-425/425
Sequence Identity: 17% (74 aa)

EIGSGALSRVYQIVSLKDN------------EILAAKVYDNQR--------------ISRPTLTG-----EDPPYVSIQRELDIMAK-------LDHRYV
..|.|. . |.  .  ...            .  |.|..| ..              |.  .  .     ..    ...||..|| |       |||. .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLIDAFNDEN---------TNS---------LIIII---PFAPLG------------NVK---------TLLDKRALNSDQLNACFHQVAIALAYMHSM
|.|.... |..         | |         ....     ... |            . .          . ... .. ..   .|.|.. |..|.||.
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSH

NVVHRDIKPENMLAFTED----------------Y-FAITDLSVSQEVESDE-----------------------TMVMDIKGSPAFLS-PEECAG----
|.||||.|||| |  . .                .   |.|   .......|                        .  .  |.|.. . ||   |    
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------TEFIPKPADVWAYGISLFSCYFGYFPF------SIDECDGLPIGNTILMVTEKLNEKELN-IPDGTSS-----------------------
          . .....|.|. |. |. .  ||.||      .| | |. .||...    ||  . . . .|.  |                        
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-DE-WIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQ

DLIDLLTHVLDKDPTKRYTFEQIANHSFF
. .||. . | .||.||.| ||. || ..
ECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 92477.m00178.AA Ciliate-E2 54-323 19 1.8e-43 147.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-365/365
Sequence Identity: 19% (74 aa)

YKFINEIGSGALSRVYQIVSLKDNEILAAKV-------------YDNQRISRPTLTGEDPPYVS----IQRELD----------IMAKLDHRYVISLIDA
||||. ||.|. . ||.    |...  | |.             .... .   ..   .  ...    | ||..          |. .|.| ..| ....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FNDENTNSLIIIIPFAPLGNVKTLLDKRALNS----------DQLNAC--FHQVA---------------IALAYMHSMN-VVHRDIKPENMLAFTEDYF
| ....|.. ..  ..  |. . .. .. ...          .   ..  . |..                || |.|| | ..|||||||| |       
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

AITDLSVSQEVESDET---------MVMDIK-----------------------GSPAFLSPEECAGTEF--------IPKPADVWAYGISLFSCYFGYF
 |.|.  |...  |.          . |. |                       |.| ...||   | .           . .|.|. |. |. . ||..
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFSIDECDGLPIGNTILMVTEKLNEK-ELNIP------------------DGTSSDLIDLLTH----VLDKDPTKRYT-FEQIANHSFF
||                  .. ... ....|                  .  | . .||.       |.||| ||.| .||| || .|
PF------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 92477.m00178.AA CAMKK 54-323 18 1.8e-39 122.66 In-house 1-396 (396) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-396/396
Sequence Identity: 18% (75 aa)

YKFINEIGSGALSRVYQIVSLKD-NEILAAKVYDN----QRISRPTLTGEDPPYV-----------------SIQRELDIMAKLDHRYVISLIDAFNDEN
|... |||.|.   | . ..  | .   | |...     ..  . . .  ||| .                  ...|. || |..| ... |.   .|..
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIKIFNKKYVFKKLKKKQQFYRDPPKRMTNMNQNGEMQMMNPFDCVYQEIAIMKKCNHPNIVKLYEVIDDPQ

TNSLIII-IPFAPLGNVKTLLDKRA--------------------------LNSDQ---------------------LNACFHQVAIALAYMH-SMN---
 ... .. . .. .| .. . ..                            ....|                     .   | ... .| |.| . .   
NDKIYMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACS

----------------VVHRDIKPENMLAFTED---YFAITDLSVSQEVESDETMVMD-----------IKGSPAFLSPEECAG-TE-------------
                ..||||||.| |   |.    . |.| .||...|...  . .           . | |||. || |    .             
YIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAPELCSKENQKENYNGYKYRFRF

-FIPKPADVWAYGISLFSCYFGYFPFSIDECDGLPIGNTILMVTE---KLNEKELNIPD-------------GTSSDLIDLLTHVLDKDPTKRYTFEQIA
 .  |.||.|| |..|.   ||  ||         ..|...   .   |  ....  |.               | ||.||..  |.|.|||| | .|| 
IYCGKAADIWALGVTLYCFVFGKCPF---------WHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEKNPTKRITIPQIK

NHSFF
.| ..
VHPWV
Kinase 92477.m00178.AA AGC 54-323 17 5.8e-36 89.21 In-house 1-395 (395) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-395/395
Sequence Identity: 17% (73 aa)

YKFINEIGSGALSRVYQIVSLK-----DN-EILAAKVYDNQR--------ISRPTLTG-------EDPPYVSIQRELDIMAKLD----------HRYVIS
..|.  || |. ..||.    .     |. .. | || . ..          . |.|               ...| .|..|..          | ....
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGY------VWEERNILEKCNHTHNHPIKSHHPFIVK

-LIDAFNDENTNSLIIIIPFAP--------LGNVKTLLDKR------ALNSDQLNACFHQ-------VAIALAYMHS-MNVVHRD-IKPENMLAFTEDYF
 |  .| |.. . | ..  ..|         |   ..| ..       .. ..    . .       .. || |.|| |...||| .||||.|   . . 
ILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHI

AITDLSVSQEVESDE--------------------------------------------------TMVMDIKG--SPAFLSPEECAGTEFIPKPADVWA-
 .||   . |. .|.                                                   .   . |  .| ...||         |..| |. 
KLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSF

-YGISLFSCYFGYFPFSIDECD---GLPIGNTILMVTEKLN-----EKELNIP----------DGTSSDLIDLLTHVLDKDPTKRYT----------FEQ
 .|. ..   .|| ||. |. .     |  |   |    .|     .... .|          .  |... ||... | |||.|| .          .|.
GLGCLMYEMLTGYPPFYGDNPQENRH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEE

IANHSFF
| || .|
IKNHPWF
Kinase 92477.m00178.AA Ciliate-E2-Unclassified 54-323 19 1.6e-35 120.68 In-house 1-352 (352) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-352/352
Sequence Identity: 19% (73 aa)

YKFINEIGSGALSRVYQIVSLKDN------EILAAKVYDNQRI----------------------SRPTLTGEDPPYVSIQRELD-IMAKLDHRYVISLI
||.|  ||.|. . ||. .  |..      ..  ...|. . |                      .             ...... |.  ..| ... ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRK-------------YNKIMQQILLNHPHPFIVKMF

DAFNDENTNSLIIIIPFAPLGNVKTLLDK------------------RALNSDQLN-----ACFHQVAIALAYMHSMN-VVHRDIKPENMLAFTED----
..|.|...  ..|.  ... |. .  . |                  . .   |         | |.  .| |.|. | ..|||||||| | |...    
YCFQDKQN--IYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENIL-FDNNGKNY

YFAITDLSVSQEVESD---------------ETMVMDIKGSPAFLS---PEECAGTEFIP----KPADVWAYGISLFSCYFGYFPFSIDECDGLP-----
|  |.|.. | . ...               . |  .. |.| ...   . |. . .       . .|.|. |. |. . |||.||.   |.        
YIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQ

-IGN--TILMVTEKLNEKELN--------IPDGTSSDLIDLLT----HVLDKDPTKRYTFEQIANHSFF
 | |  ..... .. ..|...        ||.. |   .|...      |.|.| ||.||||| || .|
WI-NNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 92477.m00178.AA LKB 104-323 27 2.3e-31 90.41 In-house 46-265 (265) Show / Hide 
Range on Protein: 104-323
Range on HMM: 46-265/265
Sequence Identity: 27% (63 aa)

SIQRELDIMAKLDHRYVISLIDAFNDENTNSLIIIIPFAPLGNVKTLLD---KRALNSDQLNACFHQVAIALAYMHSMNVVHRDIKPENMLAFTEDYFAI
....|. |. .. || || ||| |. |    . ..  .   | .  .||   .. .   | .. | |   .. |.||  |||.|||| |.|  ..    |
NVKKEIQILKRMHHRHVIQLIDVFYNEEKQKMYMVMEYCVCGTMQEMLDMQPCKRMPIWQAHFYFCQLCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKI

TDLSV---SQEVESDETMVMDIKGSPAFLSPEECAG--TEFIPKPADVWAYGISLFSCYFGYFPFSIDECDGLPIGNTILMVTEKLNEKELNIPD--GTS
 |. |   ..  . |..      |||||  ||   |  . | .  .|.|. |. |.    | .||.         |  ..   |     .. .|      
CDFGVAEQLHHFQRDDCCTT-SQGSPAFQPPECANGNHDTFSGFKVDIWSMGVTLYNMTTGKYPFE---------GDNMYKLFENIGKCQWEMPCWYDCD

SDLIDLLTHVLDKDPTKRYTFEQIANHSFF
 || .|..  |..|. || . .|| .|. |
KDLQNLIKGMLQYDHNKRFSCHQIMHHPWF
Kinase 92477.m00178.AA ULK 54-323 20 3e-31 106.39 In-house 1-329 (329) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-329/329
Sequence Identity: 20% (67 aa)

YKFINEIGSGALSRVYQIVSLKD----NEILAAKVYDNQRISRPTLT--GEDPPYVSIQRELDIMAKLD--------HRYVISLIDAFNDENTNSLIIII
|  ....|.|.  .||.    |.    ||. |.|. | | ...      | .    ....| .|| ||.        | ... |.| |.. | | . || 
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEG-QYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

PFAPLGNVKTLLDKRA-----------LNSDQLNACFHQVAIALAYMHSMNVVHRDIKPENMLAFTEDYFA-------------ITDLSVSQEVESD---
 . . |. .... |.            |. ..    |.| . .. ..|..|..||||||.| |  ...                |.|   .. |..|   
EYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNIL-IHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNME

--ETMVMD----IKGSPAFLSPEECA----GTEFIPKPADVWAYGISLFSCYFGYFPFSIDECDGLPIGNTILMVTE------KLNEKELNIPDG-----
   .| .     ..|.| . .|.       . ..  . .|.|  |. .. . .|. ||.      . . . .  .        . . . |..|.      
QQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQ

TSSDLIDLLTHVLDKDPTKRYTFEQIANHSFF
 |....||.   | .|...| ..|.. || .|
ISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 92477.m00178.AA ULK 54-323 18 3.8e-31 107.79 In-house 1-324 (324) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-324/324
Sequence Identity: 18% (63 aa)

YKFINEIGSGALS-RVYQIVSLKD---NEILAAKVYD--NQRISRPTLTGEDPPYV--------SIQRELDIMAKLD------HRYVISLIDAFNDENTN
|  ....|.|.    ||.    |.   |.. |.|. |  .....         ..         ....|  || ||.      | ... |.| |.. | |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKK---------KNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHN

SLIIIIPFAPLGNVKTLLDKRA----------LNSDQLNACFHQVAIALAYMHSMNVVHRDIKPENMLAFTEDYFA-------------ITDLSVSQEVE
 . ||  . . |. .... |.           |. ..    |.| . .. ..|..|..||||||.| |  ...                |.|   .. |.
NIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNIL-IHNGQPKTDSKKVHPNGVLKIADFGFAKHVD

SDE---TMVMDIK------GSPAFLSPEECA----GTEFIPKPADVWAYGISLFSCYFGYFPFSIDECDGLPIGNTILMVTEK------LNEKELNIPD-
...   .| . ..      |.| . .|.       . ..  . .|.|  |. .. . .|. ||. .    . ..  . ..  .       . . ...|. 
NNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKP

----GTSSDLIDLLTHVLDKDPTKRYTFEQIANHSFF
      |....||.   | .|...| ..|.| || .|
PKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 92477.m00178.AA STE 54-323 17 3.4e-27 93.15 In-house 1-359 (359) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-359/359
Sequence Identity: 17% (67 aa)

YKFINEIGSGALSRVYQIVSLK---------------DNEILAAKVYD------------NQRISRPTLTGEDPPYVSIQRELDIMAKLD--HRYVISLI
...| .||.||   ||. .  |                .|| | |. .            | . .  . .  .    .|..|..|| |..  | ...  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQEN-Q-E--LENKNHEEMQQILKEIKIMKKCNHMHPNIVKYY

DAFNDE-----NTNSLIIIIPFAPLGNVKTLLD---KRALN------------SDQLNACFHQVAIA-LAYMHSMNVVHRDIKPENMLAFTEDYFAITDL
... .|     | ..| |.  . . | .  ...   ..  .             .|. .  .|.  . |.| ||....|||||| | |        ..| 
GCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDF

SVSQEVESD-------------ETMV-M--DIKGSPAFLSPEECAGTEFIPK------PADVWAYGISL-------FSCYFGYFP---FSID-------E
 |.  ....             |||. .   . |.| . .||   . .   .       .|.|  |. .         .  .. .   | |        .
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQ

CDGLPIGNTILMVTEKLNEKELNIPDGTS-------------------SDLIDLLTHVLDKDPTKRYTFEQIAN--HSFF
           ..   .|..   .|| .|                   ....| . . |.||| || | .|  .  |.|.
---------FEQL-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 92477.m00178.AA CAMKL 54-189 22 1.8e-24 74.85 In-house 1-157 (297) Show / Hide 
Range on Protein: 54-189
Range on HMM: 1-157/297
Sequence Identity: 22% (36 aa)

YKFINEIGSGALSRVYQIVS-LKDNEILAAKVYDNQRIS-RPTLTGEDPP------YVSIQRELDIMAKLD---HRYVISLIDAFNDENT----NSLIII
|... ..| |. . |   .  .  .|  | |..| ..|. .|  .  ...         |.||  || .|.   |  .|.| . . ....    . . ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

IPFAPLGN--VKTLLDKR-----ALNSDQLNACFHQVAIALAYMHSMNVVHRDIKPEN
   .. |.      ..|.      .  ..    | |.  |..|.||...|||||||||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPEN
Kinase 92477.m00178.AA CAMKL 221-323 27 1.5e-19 58.96 In-house 195-297 (297) Show / Hide 
Range on Protein: 221-323
Range on HMM: 195-297/297
Sequence Identity: 27% (30 aa)

GSPAFLSPEECAG--TEFIPKPADVWAYGISLFSCYFGYFPFSIDECDGLP----IGNTILMVTEKLNEKELNIPDGTSSDLIDLLTHVLDKDPTKRYTF
|||.. .|| ..|  .... ...|.|. |. |.   .||.||   ..| ..      .  |.  ..   .. .|.   | |..||. . | ..|.||.| 
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPF---DDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTI

EQIANHSFF
.|| || ..
HQIMNHPWM
Kinase 92477.m00178.AA TyrKc 54-323 20 1.1e-12 -17.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 54-323
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

YKFINEIGSGALSRVYQIVSLKDNEILAAKVYDNQRISRPTLTGEDPPYVSIQRELDIMAKL--DHRYVISLIDAFNDE-----NTNSLIIIIPFAPLGN
 ... ..|.||  .||. .     .  | |.  .                 . ||. || ||  .|  .. |. .  ..         | |.  ..|.|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGD

VKTLLDKRA--LNSDQLNACFHQVAIALAYMHSMNVVHRDIKPENMLAFTEDYFAITDLSVSQEVESD-------ETMVM----DIKG-SPAF-LSPEEC
 |  | |.   |. ..|    .|.|   .| ||.|..|||.   | |   .    |.|   | ....|       .. ..    . |.  |   ..||  
LKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

AGTEFIPKPADVWAYGISL---FSCYFGYFPFSIDECDGLPIGNTILMVTEKLNEK-ELNIPDG--------TSSDLIDLLTHVLDKDPTKRYTFEQIAN
   .| .|  |||..|. .   |.  .|  | . ..    .. |. ..  |.. .   . .|.          .... .. .   . || .| ||..|  
NYGKFTTK-SDVWSFGVCMWEIFT--YGQQPYPGMIQQ--MMSNQEVI--EYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--

HSFF
|..|
HECF
Kinase 92477.m00178.AA Pkinase_Tyr 107-185 26 2.4e-08 28.88 Pfam 52-137 (270) Show / Hide 
Range on Protein: 107-185
Range on HMM: 52-137/270
Sequence Identity: 26% (23 aa)

RELDIMAKL-DHRYVISLIDAFN-DENTNSLIIIIPFAPLGNVKTLLDKR-----ALNSDQLNACFHQVAIALAYMHSMNVVHRDI
||. || .| .|  ...|. .   ..  |...|. ...|.|. .. | |.     .|.  .|    .|.| ...| .|.| .|||.
REAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL