84774.m00082

Species: T.vaginalis
Alias: 84774.m00082, TvagK0652
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK2

Sequence

Name Sequence Type Origin Length Description Download
84774.m00082.AA Protein None 347 None Fasta, JSON
84774.m00082.kin_dom Protein Kinase Domain None 307 None Fasta, JSON

Protein domain

Protein domains of 84774.m00082.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84774.m00082.AA DYRK 37-343 31 1.7e-68 233.87 In-house 1-320 (320) Show / Hide
Range on Protein: 37-343
Range on HMM: 1-320/320
Sequence Identity: 31% (103 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIVKLD-CSADYGAIEVNLNLKLQNLLTDEEKMNIVQMEGCFTYEGHAVIIYEILGQDMYSILQKNNFRPM
|. || .|.| |. |  ..| . |.. | ||..     .. . ||... |.. |   ...|...|.|  .|.. .|  |. | | .. |  | .|.|.. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKI-LEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGF

-NLKMIRLIFKDIAKACQALHKN-KLIHADSKPENI---SH-IKNTIISKLVDLGGIVEEEECLSGYFITRYYRAPEIVLSYPITTAADIWSLACTIAEL
 .|. .| . . | ..   |||| ..||.| |||||   ..  |.||  |..| |   .|.. .. |   |.|||||. | .|  .| |.||| |..|||
FSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLKQPRNKSTI--KVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAEL

ALGLPLFWAENENFMLRRMSRIIGEFPQEMLQNA--PLKDKFFENGTFIDESTWCAINNRPQHKT----------------HCTYPGVKSLDDFVVQGDP
 .| |||  |||. .|...  ..| .|..|....  . |.|||..       ..| . .......                .. .|| ...|..  . | 
FTGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC------FMYCECDEWTKQNKITDHYMTPKCHPTKRGQRRPPGRRNWDPRHQCDDH

NSALFWDLLKKMLVFDPKKRITAQEILQHPFI
   .| |..||.|..||.||||... ||||..
---QFKDFIKKCLQWDPHKRITPSQALQHPWF

Kinase 84774.m00082.AA CMGC 37-343 17 3.7e-59 192.63 In-house 1-513 (513) Show / Hide
Range on Protein: 37-343
Range on HMM: 1-513/513
Sequence Identity: 17% (91 aa)

YTLLEKLGSGNFADVYLAKD--------------DRYNQYYACKIVKLDCSADYGAI----------EVNLNLKLQNLLTDEE--------------KMN
|. ..|.|.| .. || ..|               ..|...| |..|..   . .|             .  .|.   | ...              . |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVQMEGCFTYEG-----------------HAVIIYEILGQDMYSILQKNNF-----RPMNL-------------KMIRLIF------KDIAKACQ--ALH
||..  .|....                 |  .. | ...| | ....|.|     |||.|              .|. ..      . | ..     .|
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCH

KNK--LIHADSKPENISHIKNTIIS-------------------KLVDLGGIVEEEEC------------------------LSGYFITRYYRAPEIVLS
...   || | |||||   .|.                      |. | |    ...                         .. |  ||.|||||| |.
SHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLG

YP----------ITTAADIWSLACTIAELALG--------LPLFWAENE-----------NFMLRRMSRIIGEFPQEMLQN-------APLKDKFFENGT
..           ||. |.||..| .||. .|         |||  ..|             .| .. ...| .. .|.|.       .. ......   
WKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNMIK

------------------FIDESTWCAINN---RPQHKTHCTYPGVKSLDD----------------FVVQGDPN----------SALFWDLLKKMLVFD
                  ...|. . .|..    |... .   . .. ...                . . .. .          . .. |||||||..|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSH-KFNHQFKRKCCDPQAIDLLKKMLQYD

PKKRITAQEILQHPFI
|.|||||...||||..
PDKRITAEQALQHPYF

Kinase 84774.m00082.AA S_TKc 37-343 20 2.4e-55 191.1 SMART 1-231 (231) Show / Hide
Range on Protein: 37-343
Range on HMM: 1-231/231
Sequence Identity: 20% (68 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIVKLDCSADYGAIEVNLNLKLQNLLTDEEKMNIVQMEGCFTYEGHAVIIYEILGQ---DMYSILQKNNFR
|..|.|.|.| |. ||.... . ....|.||.|     .    |...  |           |||.. ..|   .|  .. | ...   |......|.. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

P----MNLKMIRLIFKDIAKACQALHKNKLIHADSKPENI--SHIKNTIISKLVDLG--GIVEEEECLSGYFITRYYRAPEIVLSYPITT-AADIWSLAC
.    ..  ..| ... |..| . .|... || | |||||  ..       |. | |   ..      . .  |..|.|||..   . .. ..|.||. |
GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

TIAELALGLPLFWAENENFMLRRMSRIIGEFPQEMLQNAPLKDKFFENGTFIDESTWCAINNRPQHKTHCTYPGVKSLDDFVVQGDPNSALFWDLLKKML
...|.. | |.|.       . .| ..||                                                           |  ..|...|.|
ILYEMLCGYPPFP------QMQMMFKKIG-----------------------------------------------------------SPEAKDFIRKCL

VFDPKKRITAQEILQ-------HPFI
..||.||.|| |.||       ||..
QKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 84774.m00082.AA DYRK2 37-343 28 7.3e-53 170.08 In-house 1-318 (318) Show / Hide
Range on Protein: 37-343
Range on HMM: 1-318/318
Sequence Identity: 28% (93 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIV----KLDCSADYGAIEVNLNLKLQNLLTDEEKMNIVQMEGCFTYEGHAVIIYEILGQDMYSILQKNNF
|..|| .|.| |. |  . |  ..|. | |..    ..   |   ..|..   ..     |.  ||.| |   |.. .|  |  | |. ..|. . ||.|
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQA---YEEIRILHHIRRQDKDNT-MNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHF

RPMNLKMIRLIFKDIAKACQALHKNKLIHADSKPENI---SHIKNTIISKLVDLGGIVEEEE-CLSGYFITRYYRAPEIVLSYPITTAADIWSLACTIAE
   .|. .|   . | .. ..||||..||.| |||||   .. ...|  |..| |    | .  .  |  .|.|||||. |  .  .| |.||. |..||
QGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSGI--KVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAE

LALGLPLFWAENENFMLRRMSRIIGEFPQEMLQNA-----PLKDKFFE-------NGTFIDESTWCAINNRPQHKTHCTYPGVKSLDDFVVQGDPNSALF
|  | |||  ||||  .  |  ..|  |.......       .. ||.       . ||. . .  .  .... . .  .|| ||. ... ..  .. .|
LYTGYPLFPGENENDQFACMMEVLGMPPKKFFDTWFYIHCFRRKYFFNSHCFEWYC-TFMTDHSMEIPKHYKNRHGKRRPPGSKSWKSVLKGC--EDENF

WDLLKKMLVFDPKKRITAQEILQHPFI
 | .|. .. ||..|.|....|.||.|
IDFIKRCFEWDPSERMTPSQALKHPWI

Kinase 84774.m00082.AA DYRK1 37-343 30 3.3e-43 149.41 In-house 1-321 (321) Show / Hide
Range on Protein: 37-343
Range on HMM: 1-321/321
Sequence Identity: 30% (100 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIVKLDCS-ADYGAIEVNLNLKLQNLLTDEEKMNIVQMEGCFTYEGHAVIIYEILGQDMYSILQKNNFRPM
|     .| | |  |  | |    .| | ||.|   .  .   ||. | | | |    |.| .||.. . | .  |  ...|.|   .| .|.  .|| .
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRL-LELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGV

NLKMIRLIFKDIAKACQALHKNKL--IHADSKPENI--SHIKNTIISKLVDLGGIVEEEECLSGYFITRYYRAPEIVLSYPITTAADIWSLACTIAELAL
 | ..| . . ...|   .    |  || | |||||     |   | |..| |   . .. .  |   |.||.||..|  .  .| |.||| | . |.  
SLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLCNPKRSAI-KIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHT

GLPLFWAENENFMLRRMSRIIGEFPQEMLQNAPLKDKFFENGTFIDESTWCAINNRPQHKTHCTYPGVKSLDDF--VVQGDPNS-------------ALF
| |||   ||   . ..  ..|  |..|.. ||   |.||     .. ||    .| ..|.    |. . |..   |  | |..               |
GEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEK---DPDNTWYCKKTRDKKKH-YKEPCTRKLHEILGVETGGPGGRRKGEPGHSVEDYLKF

WDLLKKMLVFDPKKRITAQEILQHPFI
 ||.|.|| .|||.|||  ..|||.|.
KDLIKRMLQYDPKQRITPYYALQHSFF

Kinase 84774.m00082.AA HIPK 37-281 34 6e-42 129.58 In-house 1-248 (329) Show / Hide
Range on Protein: 37-281
Range on HMM: 1-248/329
Sequence Identity: 34% (86 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIVKLDCS-ADYGAIEVNLNLKLQNLLTDEEKMNIVQMEGCFTYEGHAVIIYEILGQDMYSILQKNNFRPM
|  || || | | .|  .     |   | || | . . |  | ||| .  .|...  ||  ...| .  ||  . |  ...|.| | .|  . .|.| |.
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADE--YHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPL

NLKMIRLIFKDIAKACQALHKNKLIHADSKPENISHIKNTIIS---KLVDLG--GIVEEEECLSGYFITRYYRAPEIVLSYPITTAADIWSLACTIAELA
 ||.|| | . ...|   | .  ||||| |||||  .  |      | .| |   .| .    . |   ||||||||.|  |.  . |.||| | |||| 
PLKHIRPILQQVLTALMKLKELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKV-VCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELF

LGLPLFWAENENFMLRRMSRIIGEFPQEMLQNAPLKDKFFENGTFIDESTW
|| ||.   .|    | ..   .   . .|. |  | .||.  . .. . |
LGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRPW

Kinase 84774.m00082.AA Pkinase 37-247 21 5.6e-35 124.77 Pfam 1-229 (293) Show / Hide
Range on Protein: 37-247
Range on HMM: 1-229/293
Sequence Identity: 21% (52 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIVKLDCSADYGAI-------EVNLNLKLQNLLTDEEKMNIVQMEGCFTYEGHAVIIYEILGQ-----DMY
|....|.|||.|. ||....  ... .|.||.|.. ... .         |. . ..|.         |||.. ..|....|  .. | ..      | .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF

SILQ---KNNFRPMNLKMIRLIFKDIAKACQALHKNKLIHADSKPENISHIKNTIIS----KLVDLGG--I--VEEEECLSGYFITRYYRAPEIVL-SYP
....   ...|  .  . .. ... |... . .|... || | |||||  |.|.       |. | |          . ....  |..|.|||... . .
DYISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI-LIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQY

ITTAADIWSLACTIAELALGLPLFWAE------NENFMLRR
.....|.||. |...|...| |.|. .      ....|..|
YGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICR

Kinase 84774.m00082.AA CLK 199-343 34 1.5e-30 88.22 In-house 210-350 (350) Show / Hide
Range on Protein: 199-343
Range on HMM: 210-350/350
Sequence Identity: 34% (51 aa)

TRYYRAPEIVLSYPITTAADIWSLACTIAELALGLPLFWAENENFMLRRMSRIIG-EFPQEMLQNAP---LKDKFF-ENGTFIDESTWCAINNRPQHKTH
|| |||||..|  .  .  |.|| .| . || .|  ||   ..   |  | || |  .|| | |       |.|.| .|..  |. .  ..  .      
TRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWMIQRTRRFKVKQKYFYHNRLDWDWHNSDGRYVMEN----

CTYPGVKSLDDFVVQGDPNSALFWDLLKKMLVFDPKKRITAQEILQHPFI
     .| |  .  . ||    . ||..||| .|| ||||....||||| 
-----CKPLKQYMDCKDPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF

Kinase 84774.m00082.AA CLK 98-169 32 1.2e-20 58.0 In-house 67-145 (350) Show / Hide
Range on Protein: 98-169
Range on HMM: 67-145/350
Sequence Identity: 32% (26 aa)

NIVQMEGCFTY-EGHAVIIYEILGQDMYSILQKNN------FRPMNLKMIRLIFKDIAKACQALHKNKLIHADSKPENI
....|. .| |  ||  |. |..|   |. . .||      ..|  .  || ... . .| . ||..||.| | |||||
HCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSNNSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENI

Kinase 84774.m00082.AA PRP4 154-271 34 1e-19 68.85 In-house 122-240 (320) Show / Hide
Range on Protein: 154-271
Range on HMM: 122-240/320
Sequence Identity: 34% (41 aa)

LHKNKLIHADSKPENISHIKNTIISKLVDLG--GIVEEEECLSGYFITRYYRAPEIVLSYPITTAADIWSLACTIAELALGLPLFWAENENFMLRRMSRI
| |.. .||| || ||    .. . |..| |  . ..|.| .  |   |.||||||.. .|   . |.|| .||..||. |  .|     | ||. .  .
LKKCNILHADIKPDNILVNESKNTLKMCDFGSASHIHENE-ITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMFPGKTNNHMLKLFMDY

IGEFPQEMLQNAPLKDKFFE
 | .|. |...  .||..|.
KGKMPNKMIRKGQFKDNHFD

Kinase 84774.m00082.AA Ciliate-E2-Unclassified 37-222 19 7.8e-19 61.98 In-house 1-256 (352) Show / Hide
Range on Protein: 37-222
Range on HMM: 1-256/352
Sequence Identity: 19% (50 aa)

YTLLEKLGSGNFADVYLAKD-DRYNQYYACKIVKLDCSADYGAIEVNLNLKLQNLLTDEEKM---------------------NIVQMEGCFTYEGHAVI
|......|.|.|..||.... . . |||| |. |   . .   |. .   ....... ..|.                     .|| |. ||. . .  |
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

IYEIL-GQDMYSILQKNNF---------------RPMNLKMIR-----LIFKDIAKACQALHKNK-LIHADSKPENISHIKNTI--ISKLVDLGGIVEEE
..| . |.|.  ...|...               .    . ..      .|. | .. . ||...  || | |||||   .|      |. |.| . . .
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

EC------------------LSGYFITRYYR----APEIVLSYPIT----TAADIWSL
..                  ..    | .|     |||.  .         ..|||||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSL

Kinase 84774.m00082.AA CDK 295-343 44 1.5e-18 55.77 In-house 248-284 (284) Show / Hide
Range on Protein: 295-343
Range on HMM: 248-284/284
Sequence Identity: 44% (22 aa)

TYPGVKSLDDFVVQGDPNSALFWDLLKKMLVFDPKKRITAQEILQHPFI
. |||..| |.            ||| |||..||||||.|.. ||||. 
NWPGVTKLPDY------------DLLNKMLCYDPKKRISAEQALQHPYF

Kinase 84774.m00082.AA Ciliate-E2 37-169 20 1e-17 57.34 In-house 1-192 (365) Show / Hide
Range on Protein: 37-169
Range on HMM: 1-192/365
Sequence Identity: 20% (39 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIVKLDCSADYG-----------AIEVNLNLKLQNLLTDEEKM----------------------NIVQME
| ...|.|.|||..||..|... .. .| || . . .  ..           |.... . ......  .  |                      ||..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

GCFT--YEGHAVIIYEILGQ-DMYSILQKN-NFR--------PMNLKMIRLIFKDIAK---------------ACQALHKNK-LIHADSKPENI
 ||    . .  .. | . . |.......|  .|        ....| |. |.| |..               | . ||...  || | |||||
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENI

Kinase 84774.m00082.AA Ciliate-E2 318-343 51 1.9e-13 42.5 In-house 335-365 (365) Show / Hide
Range on Protein: 318-343
Range on HMM: 335-365/365
Sequence Identity: 51% (16 aa)

DLLKK----MLVFDPKKRIT-AQEILQHPFI
||.||    ||. ||.|||| ...||.||..
DLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 84774.m00082.AA Ciliate-E2-Unclassified 318-343 57 4.5e-12 38.18 In-house 327-352 (352) Show / Hide
Range on Protein: 318-343
Range on HMM: 327-352/352
Sequence Identity: 57% (15 aa)

DLLKKMLVFDPKKRITAQEILQHPFI
|||.|||. .|.||||...||.||..
DLLQKMLKKNPNKRITFEQILNHPWF

Kinase 84774.m00082.AA PRP4 316-343 67 2.9e-11 37.54 In-house 293-320 (320) Show / Hide
Range on Protein: 316-343
Range on HMM: 293-320/320
Sequence Identity: 67% (19 aa)

FWDLLKKMLVFDPKKRITAQEILQHPFI
| ||| |.|. |||||||  | |.||||
FKDLLDKCLMLDPKKRITCNEALKHPFI

Kinase 84774.m00082.AA Pkinase 318-343 57 4.8e-11 40.15 Pfam 268-293 (293) Show / Hide
Range on Protein: 318-343
Range on HMM: 268-293/293
Sequence Identity: 57% (15 aa)

DLLKKMLVFDPKKRITAQEILQHPFI
|..|..| .|||||.||..|||||..
DFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 84774.m00082.AA CDK 198-241 38 8.4e-11 30.63 In-house 181-230 (284) Show / Hide
Range on Protein: 198-241
Range on HMM: 181-230/284
Sequence Identity: 38% (19 aa)

ITRYYRAPEIVL-SYPIT--TAADIWSLACTIAELAL---GLPLFWAENE
.|. |||||. | |   .  |. |.||. | .||...   . |||  ..|
VTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSE

Kinase 84774.m00082.AA HIPK 316-343 53 4.3e-09 24.25 In-house 302-329 (329) Show / Hide
Range on Protein: 316-343
Range on HMM: 302-329/329
Sequence Identity: 53% (15 aa)

FWDLLKKMLVFDPKKRITAQEILQHPFI
| ..||||.. |..||||  | |.|||.
FVHVLKKMCTWDAHKRITPCEALNHPFV

Kinase 84774.m00082.AA CDK 37-71 32 4.5e-07 18.51 In-house 1-40 (284) Show / Hide
Range on Protein: 37-71
Range on HMM: 1-40/284
Sequence Identity: 32% (13 aa)

YTLLEKLGSGNFADVYLAKDDRYN-----QYYACKIVKLD
|  |||.| | .. || |.| . .     |..| | ....
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRME

Kinase 84774.m00082.AA TyrKc 37-343 16 3e-06 -121.6 SMART 1-280 (280) Show / Hide
Range on Protein: 37-343
Range on HMM: 1-280/280
Sequence Identity: 16% (59 aa)

YTLLEKLGSGNFADVYLAKDDRYNQYYACKIVKLDCSADYGAIEVNLNLKLQ---NLLTDE--EKMNIVQMEGCFTYE-------GHAVIIYEILGQ-DM
 ||..|||.|.|  ||... .   .  | | .| |.              .    ....    .  |||.. |. | .       .   |. |     | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

YSILQKNNFRPMNLKMIRLIFKDIAKACQALHKNKLIHADSKPENISHIKNTII-------SKLVDLG---GIVEEEECL-----SGY--FITRYYRAPE
 . |.|.  .  ..|    .  .||. .. ||....|| |    |.   .| ..       |. .. .   | ....        .|   .  | . |||
KDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-ESKDYYRKKEHKGGKTMLPIRWM-APE

IVLSYPITTAADIWSLACTIAELA-LGLPLFWA------ENENFMLRRMSRIIGEFPQE---MLQNAPLKDKFFENGTFIDESTWCAINNRPQHKTHCTY
    .  ||. |.||   .. |.  .| .  .       .|.  . . ...   . |..   |                                     
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------------

PGVKSLDDFVVQGDPN-SALFWDLLKKMLVFDPKKRITAQEILQHPFI
        |     .  ..   .. |.   .||..| | .||  | ..
--------F-----VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF

Kinase 84774.m00082.AA CLK 37-69 32 1.1e-05 12.19 In-house 1-34 (350) Show / Hide
Range on Protein: 37-69
Range on HMM: 1-34/350
Sequence Identity: 32% (11 aa)

YTLLEKLGSGNFADVYLAKDDRY-NQYYACKIVK
|. . .||.| |  |.  .| .. ..|.| ||..
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIR

Kinase 84774.m00082.AA Ciliate-E2 199-222 33 0.002237 7.43 In-house 250-282 (365) Show / Hide
Range on Protein: 199-222
Range on HMM: 250-282/365
Sequence Identity: 33% (11 aa)

TRYYRAPEIVL---------SYPITTAADIWSL
| .| ||||.          . . ....|||||
TPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSL

Kinase 84774.m00082.AA PRP4 37-68 30 0.051172 3.28 In-house 1-33 (320) Show / Hide
Range on Protein: 37-68
Range on HMM: 1-33/320
Sequence Identity: 30% (10 aa)

YTLLEKLGSGNFADVYLAK-DDRYNQYYACKIV
|    . |.| |. |  ..  .| |.  | ||.
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKII