Gene GL50803_10744 (G.lamblia)
GL50803_10744
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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GL50803_10744.AA | Protein | None | 1120 | None | Fasta, JSON |
GL50803_10744.kin_dom | Protein Kinase Domain | None | 254 | None | Fasta, JSON |
Protein domains of GL50803_10744.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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S_TKc | GL50803_10744.AA | S_TKc | 19-280 | 18 | 3e-11 | -12.03 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 19-280 Range on HMM: 1-231/231 Sequence Identity: 18% (53 aa) PELGPVVGSGYLGQVRTLTNSPGHITEEVRLDVLQESEKTSIRRILHLATTLSHPNIIPIESIFETSSVIYASMERPPC---TLETLIKEAKDSKRK--I |.. ..|.| |.|. .. ..| . .. .. .| | | ||||. . .|.. . .| || . .| ..||. . ... . YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK---EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF PSDTVLLAILQIAEAITYLH-------------------------GFATASGDTIKTSKVTYKALQPSNVFVGCNGCRFLISAIGICIEHEQTDTCFYSA | .. . ||..|. |.| |.|. . . | .| | PE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL--------------------------------------TTFCGTPWYMA PEILIHNRCSA-ASVMWSLGVITYELATGIRPNFRRTTDPRLVFVQDWKPDLILVRDKEIKKIIERLLVVTEEHRITAPELVN-LLRSNKHVAK ||.| . .. .||.|.| ||...| | .. ..| . ..| | .|...|.. |.|.|| |. . . ..| PEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | GL50803_10744.AA | Pkinase | 185-272 | 20 | 1e-10 | 38.95 | Pfam | 176-293 (293) | Show / Hide |
Range on Protein: 185-272 Range on HMM: 176-293/293 Sequence Identity: 20% (24 aa) FYSAPEILI-HNRCSAASVMWSLGVITYELATGIRPNFRRT-----TDPRLVFVQDWKPDLILVRD-----------------------KEIKKIIERLL .| |||.. .. . .. |||.|.| ||...| | |. |.. ..... .|.| .. .| |..|...| WYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR-PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCL VVTEEHRITAPELVNL--L . . |.||..... . CKDPKKRPTAEQILQHPWF |
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Kinase | GL50803_10744.AA | Ciliate-E2 | 186-270 | 18 | 2.8e-08 | 24.51 | In-house | 253-361 (365) | Show / Hide |
Range on Protein: 186-270 Range on HMM: 253-361/365 Sequence Identity: 18% (24 aa) YSAPEILI---------HNRCSAASVMWSLGVITYELATGIRPNFRRTTDPRLVFVQDWKPDLILVRDKEIK---------------------------- | ||||| ... . .. .|||||| ||. .| .| .. ...|. YMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECK KIIER----LLVVTEEHRIT-APELVN .| . .|.. .| ||| . .. | DLIKKFGKRMLQKDPEKRITGWEQILN |
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Kinase | GL50803_10744.AA | DRAK | 186-219 | 50 | 1.5e-07 | 18.89 | In-house | 167-200 (259) | Show / Hide |
Range on Protein: 186-219 Range on HMM: 167-200/259 Sequence Identity: 50% (17 aa) YSAPEILIHNRCSAASVMWSLGVITYELATGIRP | ||||| . . | ||| ||.|| . |.| | YVAPEILNYDPITMATDMWSIGVLTYVMLTHISP |
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Kinase | GL50803_10744.AA | SNRK | 186-274 | 32 | 2.1e-07 | 20.01 | In-house | 165-254 (254) | Show / Hide |
Range on Protein: 186-274 Range on HMM: 165-254/254 Sequence Identity: 32% (29 aa) YSAPEILIHNRCSAASV-MWSLGVITYELATGIRPNFRRTTDPRLVFVQDWKPDLILVRDKEIKKIIERLLVVTEEHRITAPELVNLLRS |||||||. | | .|||||| | | | | . | . | | . . .| . .|...|| ..| . |.|. YSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFQEANDSETLTMIMDCKYTVPDHVSDECRDLIQSMLVRDPKKRASLEEIVSHSWV |
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Kinase | GL50803_10744.AA | AGC | 183-219 | 43 | 8.6e-07 | 12.04 | In-house | 270-304 (395) | Show / Hide |
Range on Protein: 183-219 Range on HMM: 270-304/395 Sequence Identity: 43% (17 aa) TCFYSAPEILIHNRCSAASVMWS--LGVITYELATGIRP | | ||||| .. | || ||.. ||. ||. | TPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPP |
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Kinase | GL50803_10744.AA | Pkinase | 64-133 | 21 | 2e-06 | 23.97 | Pfam | 51-125 (293) | Show / Hide |
Range on Protein: 64-133 Range on HMM: 51-125/293 Sequence Identity: 21% (16 aa) LHLATTLSHPNIIPIESIFETSSVIYASMERPPCTLETLIKEA----KDSKRKI--PSDTVLLAILQIAEAITYLH ... |.||||. . .||... || || ...|. .. . ...... . ... ..||.... |.| IQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCH |
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Kinase | GL50803_10744.AA | MSK | 186-219 | 41 | 1.8e-05 | 14.47 | In-house | 171-209 (277) | Show / Hide |
Range on Protein: 186-219 Range on HMM: 171-209/277 Sequence Identity: 41% (16 aa) YSAPEILI----HNR-CSAASVMWSLGVITYELATGIRP | |||.| .. ..| .||||||.|.. || .| YMAPEMLRRGYAQDGGYDEACDWWSLGVILYTMLTGQVP |
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TyrKc | GL50803_10744.AA | TyrKc | 19-272 | 16 | 1.9e-05 | -134.39 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 19-272 Range on HMM: 1-280/280 Sequence Identity: 16% (52 aa) PELGPVVGSGYLGQVR--TLTNSPGHITEEVRLDV----LQESEKTSIRRILHLATTL--SHPNIIPIESIFETS-------SVIYASME--RPPCTLET .|| . |.| |.|. |.. ..| |.|. . ..| . . . | .||||. . . .. .. || . .. ITLGKKLGEGAFGEVYKGTWK-----------IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY LIKEAKDSKRKIPSDTVLLAILQIAEAITYLHGFATASGDTIKTSKVTYKALQPSNVFVGCNG-CRFLISAIGICIEHEQT----------------DTC | | .. .. .. | .|||. ||| .. | |. || |. .. || | . ... .. LRKHRPK----LCMKDLLSFCWQIACGMEYLHSK-----------NCIHRDLAARNCLVGENHTVK--ISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK -----FYSAPEILIHNRCSAASVMWSLGVITYELATGIRPNFRR-----TTDPRLV-FVQDW-KPDLILV--------RDKEIKKIIERLLVVTEEHRIT ||| . ..... .| || || .|. | . .. ... .|.. .. .|. .|... | | | TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPT APELVNLL |.. .. FSEIHECF |
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Kinase | GL50803_10744.AA | RTKK | 188-219 | 51 | 1.9e-05 | 14.21 | In-house | 186-218 (272) | Show / Hide |
Range on Protein: 188-219 Range on HMM: 186-218/272 Sequence Identity: 51% (17 aa) APEILIHNRCSAASVMWSLGVITYEL-ATGIRP .|| ||| | | || ||||. | . | || SPESLIHRRFSPASDVWSLGMTAWEICSNGQRP |
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Kinase | GL50803_10744.AA | CAMK | 70-133 | 16 | 2.8e-05 | 12.19 | In-house | 95-196 (425) | Show / Hide |
Range on Protein: 70-133 Range on HMM: 95-196/425 Sequence Identity: 16% (17 aa) LSHPNIIPIESIFE------------TSSV--------IYASM---ERPPCT------LETLIKE-----------AKDSKRKIPSDTVLLAILQIAEAI |.||||| . ..| | | .| | | . .. ... ...... . . . ||..|. LDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAV TYLH |.| HYCH |
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Kinase | GL50803_10744.AA | CAMK-Unique | 69-133 | 14 | 2.9e-05 | 13.11 | In-house | 72-174 (363) | Show / Hide |
Range on Protein: 69-133 Range on HMM: 72-174/363 Sequence Identity: 14% (15 aa) TLSHPNIIPIESI----FETSS---------------VIYASMERPPCT-LETLIKEA----------------KDSKRKIPS--DTVLLAILQIAEAIT ...|||||... . |... .| ||. .. | .| . |..... ... ......|. MVDHPNIIKLYDWNNPIFCDRKYPLCDLIIKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVA YLH |.| YMH |
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Kinase | GL50803_10744.AA | DAPK | 186-219 | 52 | 3e-05 | 10.09 | In-house | 172-205 (264) | Show / Hide |
Range on Protein: 186-219 Range on HMM: 172-205/264 Sequence Identity: 52% (18 aa) YSAPEILIHNRCSAASVMWSLGVITYELATGIRP | ||||. | | ||| ||||| . .|| | YVAPEIVNYEPLSLATDMWSIGVITYIMLSGISP |
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Kinase | GL50803_10744.AA | CAMK-Unique | 197-219 | 56 | 0.000122 | 11.02 | In-house | 270-292 (363) | Show / Hide |
Range on Protein: 197-219 Range on HMM: 270-292/363 Sequence Identity: 56% (13 aa) CSAASVMWSLGVITYELATGIRP || || ||||||.|....|. | CSPASDIWSLGVIMYYMLCGCPP |
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Kinase | GL50803_10744.AA | CAMK | 186-270 | 18 | 0.000258 | 9.02 | In-house | 285-421 (425) | Show / Hide |
Range on Protein: 186-270 Range on HMM: 285-421/425 Sequence Identity: 18% (25 aa) YSA-PEILIHNR--------------CSAASVMWSLGVITYELATGIRPNFRRTT-----------DPRLVFVQDWKPDLILVRDK-------------- | | ||.| .. .. .. |||.|||.| . .| | . ... | . | . .. YMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWD ------------EIKKIIERLLVVTEEHRITAPELVN | | | ..|.| |.|.|. . | DISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN |
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Kinase | GL50803_10744.AA | PSK | 70-93 | 41 | 0.001399 | 6.95 | In-house | 53-76 (258) | Show / Hide |
Range on Protein: 70-93 Range on HMM: 53-76/258 Sequence Identity: 41% (10 aa) LSHPNIIPIESIFETSSVIYASME ..||.|| . .|||.. .| || VRHPYIIQLMEVFETQDRVYMVME |
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Kinase | GL50803_10744.AA | PSK | 186-219 | 44 | 0.002924 | 5.91 | In-house | 166-199 (258) | Show / Hide |
Range on Protein: 186-219 Range on HMM: 166-199/258 Sequence Identity: 44% (15 aa) YSAPEILIHNRCSAASVMWSLGVITYELATGIRP | |||.|. . || .|||.| | || | YIAPEVLLRKPYTQSVDMWAVGVIAYILMSGIMP |
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Kinase | GL50803_10744.AA | Ciliate-E2 | 49-133 | 18 | 0.07387 | 2.14 | In-house | 52-177 (365) | Show / Hide |
Range on Protein: 49-133 Range on HMM: 52-177/365 Sequence Identity: 18% (23 aa) LDVLQESEKTSIRRILHLAT----------------TLSHPNIIPIESIFE--TSSVIYASMERPPC-TLETLIKEAKDSKRKIPS-------DTVLLAI . ....... .| ...|. .|.||||| . |. . . || || .|. .||. | .. .... .. . MKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIM LQIAE---------------AITYLH ||.. |. ||| KQILQGFKTKAEFYIACIILALEYLH |
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Ank | GL50803_10744.AA | Ank | 364-385 | 36 | 0.001065 | 17.6 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 364-385 Range on HMM: 1-22/33 Sequence Identity: 36% (8 aa) IGRTALMRAADKGDAEMVRLLI |.|.|. |. .|..|.|..|. DGFTPLHLACRCGHTEVVKMLL |
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Ank | GL50803_10744.AA | Ank | 405-428 | 37 | 0.014776 | 13.48 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 405-428 Range on HMM: 1-24/33 Sequence Identity: 37% (9 aa) QNRTALMGAAVNGHLEAVRALLDY .|.|. |. .||.| |. ||.. DGFTPLHLACRCGHTEVVKMLLQH |
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Ank | GL50803_10744.AA | Ank | 436-462 | 48 | 0.000102 | 21.27 | Pfam | 1-25 (33) | Show / Hide |
Range on Protein: 436-462 Range on HMM: 1-25/33 Sequence Identity: 48% (13 aa) DGLTALMLATCNGHTEAARILVEKEHG || |.|.|| ..|||| .. |.. || DGFTPLHLACRCGHTEVVKMLLQ--HG |
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Ank | GL50803_10744.AA | Ank | 498-526 | 31 | 0.000144 | 20.73 | Pfam | 1-29 (33) | Show / Hide |
Range on Protein: 498-526 Range on HMM: 1-29/33 Sequence Identity: 31% (9 aa) NGWTALMRAAEKGYKKLIRLLLQLEAKIH .|.|.|. |...|... ...||| | .. DGFTPLHLACRCGHTEVVKMLLQHGADVN |
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Ank | GL50803_10744.AA | Ank | 467-497 | 18 | 0.000376 | 19.23 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 467-497 Range on HMM: 1-33/33 Sequence Identity: 18% (6 aa) EGWSALMYAAESNQVDIAQLLLN--TEKALQNS .|...|..|...........||. . .|. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Ank | GL50803_10744.AA | Ank | 529-550 | 40 | 0.000335 | 19.41 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 529-550 Range on HMM: 1-22/33 Sequence Identity: 40% (9 aa) HGLTALMYSAWSGHSEIVALLL .| |.|.. . .|| |.| .|| DGFTPLHLACRCGHTEVVKMLL |
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Ank | GL50803_10744.AA | Ank | 560-590 | 33 | 7.2e-07 | 29.04 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 560-590 Range on HMM: 1-33/33 Sequence Identity: 33% (11 aa) DGWTALMYAAYNGHSDVVQILMD--TEKRAVNK ||.|.|..|...|| .||. |.. . |... DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Ank | GL50803_10744.AA | Ank | 591-621 | 36 | 5.3e-05 | 22.3 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 591-621 Range on HMM: 1-33/33 Sequence Identity: 36% (12 aa) DGRSALMRAAENGHTEAVRLLVG--QEKGIQDN ||...|. |...|||| |..|.. . .||. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Ank | GL50803_10744.AA | Ank | 622-645 | 25 | 0.084428 | 10.75 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 622-645 Range on HMM: 1-24/33 Sequence Identity: 25% (6 aa) NGLSSMMYAVWNNYTDIVEVLHDH .| . ..|. ...|..|. | .| DGFTPLHLACRCGHTEVVKMLLQH |
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Ank | GL50803_10744.AA | Ank | 653-673 | 33 | 0.296957 | 8.78 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 653-673 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) EGWTALLYAIDKKNTDAVQIL .|.|.| .|. . .|. |. | DGFTPLHLACRCGHTEVVKML |
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Ank | GL50803_10744.AA | Ank | 684-705 | 27 | 16.991725 | 2.44 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 684-705 Range on HMM: 1-22/33 Sequence Identity: 27% (6 aa) GNHTALEYALQSGYSDAIRILL |.| .| ..|. . .. || DGFTPLHLACRCGHTEVVKMLL |
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Ank | GL50803_10744.AA | Ank | 714-735 | 36 | 0.000508 | 18.76 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 714-735 Range on HMM: 1-22/33 Sequence Identity: 36% (8 aa) LGRTALMRAADRGDTDMVSLLI |.|.|. |. .|.|..|..|. DGFTPLHLACRCGHTEVVKMLL |
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Ank | GL50803_10744.AA | Ank | 755-775 | 42 | 1.531925 | 6.21 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 755-775 Range on HMM: 1-21/33 Sequence Identity: 42% (9 aa) CYRTALMGAVANGHTASVKIL . .|.|. |. .||| || | DGFTPLHLACRCGHTEVVKML |
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Ank | GL50803_10744.AA | Ank | 817-846 | 36 | 4.2e-05 | 22.65 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 817-846 Range on HMM: 1-33/33 Sequence Identity: 36% (12 aa) SGRTALMLAAQNGSYEVATILLD---SERALTD |.|.|.||...|..||.. ||. . | .| DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Ank | GL50803_10744.AA | Ank | 786-816 | 21 | 0.001484 | 17.08 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 786-816 Range on HMM: 1-33/33 Sequence Identity: 21% (7 aa) DGWTALMVAACINNAEAAAILVG--KERCIRTS ||.|.|..|.. ...| . |.. . .... DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Ank | GL50803_10744.AA | Ank | 848-871 | 25 | 9.446981 | 3.36 | Pfam | 1-24 (33) | Show / Hide |
Range on Protein: 848-871 Range on HMM: 1-24/33 Sequence Identity: 25% (6 aa) SARTATMTAAWTNYPEIVNILLKY .|. . |. ...|.| ||.. DGFTPLHLACRCGHTEVVKMLLQH |
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Ank | GL50803_10744.AA | Ank | 879-900 | 50 | 0.000146 | 20.71 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 879-900 Range on HMM: 1-22/33 Sequence Identity: 50% (11 aa) DGWTALMCAAVQGHVEPLKLLL ||.|.|..|. ||.| .|.|| DGFTPLHLACRCGHTEVVKMLL |
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Ank | GL50803_10744.AA | Ank | 910-942 | 30 | 7.3e-05 | 21.79 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 910-942 Range on HMM: 1-33/33 Sequence Identity: 30% (10 aa) DGWTALMLAANNSHAEATRLLMTCPEELQASES ||.|.|.||. . |.| ..|. . .. | DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Ank | GL50803_10744.AA | Ank | 971-993 | 30 | 0.05793 | 11.34 | Pfam | 1-23 (33) | Show / Hide |
Range on Protein: 971-993 Range on HMM: 1-23/33 Sequence Identity: 30% (7 aa) RGRTALMIAAENDWPEVLVPLID |.|.|..|.... .||. |.. DGFTPLHLACRCGHTEVVKMLLQ |
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Ank | GL50803_10744.AA | Ank | 1002-1022 | 47 | 0.025262 | 12.64 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1002-1022 Range on HMM: 1-21/33 Sequence Identity: 47% (10 aa) DGCTALMLAGRNGSLESARIL ||.|.|.|| |.|..| .. | DGFTPLHLACRCGHTEVVKML |
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Ank | GL50803_10744.AA | Ank | 1033-1063 | 30 | 0.000112 | 21.13 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 1033-1063 Range on HMM: 1-33/33 Sequence Identity: 30% (10 aa) NGQTALMEAAKGGYPDVVQVLVE--YEKCLQDA .|.|.|. |.. |...||. |.. . ..|| DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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Ank | GL50803_10744.AA | Ank | 1064-1084 | 42 | 0.000226 | 20.03 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1064-1084 Range on HMM: 1-21/33 Sequence Identity: 42% (9 aa) DGNTALMVAVAEGCQDVVEIL ||.|.|..|. |. .||. | DGFTPLHLACRCGHTEVVKML |
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Ank | GL50803_10744.AA | Ank | 1095-1112 | 38 | 60.038757 | 0.46 | Pfam | 1-18 (33) | Show / Hide |
Range on Protein: 1095-1112 Range on HMM: 1-18/33 Sequence Identity: 38% (7 aa) AGQTALDLARSSGREEML |.|.| || ..|..|.. DGFTPLHLACRCGHTEVV |