Gene GL50803_11355 (G.lamblia)
GL50803_11355
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_11355.AA | Protein | None | 1412 | None | Fasta, JSON |
| GL50803_11355.kin_dom | Protein Kinase Domain | None | 213 | None | Fasta, JSON |
Protein domains of GL50803_11355.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | GL50803_11355.AA | Trio | 234-259 | 53 | 1.4e-09 | 20.07 | In-house | 233-258 (258) | Show / Hide |
Range on Protein: 234-259 Range on HMM: 233-258/258 Sequence Identity: 53% (14 aa) DFIDKLLVEDDRIRPTATEALQNPKF .|| |.|.|| . ||.| |.||.| | HFICKVLQEDPWKRPCASECLQHPWF |
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| Kinase | GL50803_11355.AA | MLCK | 229-259 | 51 | 2.2e-08 | 17.68 | In-house | 227-257 (257) | Show / Hide |
Range on Protein: 229-259 Range on HMM: 227-257/257 Sequence Identity: 51% (16 aa) SEEIADFIDKLLVEDDRIRPTATEALQNPKF |.| |||..|||.| . |.||.|.|| | . SDEAKDFISRLLVKDKEKRMTAHECLQHPWL |
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| Kinase | GL50803_11355.AA | CAMK | 223-259 | 24 | 1.9e-07 | 19.31 | In-house | 381-425 (425) | Show / Hide |
Range on Protein: 223-259 Range on HMM: 381-425/425 Sequence Identity: 24% (11 aa) DLRSNYSEE--------IADFIDKLLVEDDRIRPTATEALQNPKF . .. |.| |.| |.|. | |.|....|. | . EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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| Kinase | GL50803_11355.AA | CK2 | 229-259 | 45 | 4.3e-07 | 16.41 | In-house | 258-288 (288) | Show / Hide |
Range on Protein: 229-259 Range on HMM: 258-288/288 Sequence Identity: 45% (14 aa) SEEIADFIDKLLVEDDRIRPTATEALQNPKF ..|. ||.||.|. | | || ||.. | | HPEAIDFLDKMLRYDHQERITAKEAMEHPYF |
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| Kinase | GL50803_11355.AA | DAPK | 226-259 | 50 | 9.5e-07 | 14.29 | In-house | 231-264 (264) | Show / Hide |
Range on Protein: 226-259 Range on HMM: 231-264/264 Sequence Identity: 50% (17 aa) SNYSEEIADFIDKLLVEDDRIRPTATEALQNPKF |. ||. ||| .||| | . |.||.|.|| | SCTSEHAKDFIRRLLVKDPEKRMTAEECLQHPWI |
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| S_TKc | GL50803_11355.AA | S_TKc | 8-259 | 15 | 2e-06 | -82.99 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 8-259 Range on HMM: 1-231/231 Sequence Identity: 15% (44 aa) ITNLGALK----SSCYIMKESSPALVHTQLIPTDLMPDKAVWMMRCVIEHFSVASSPFLVDIKTVAAPYAGVIKFREKWY----------VGT---SLRS . | . ...| .. . .. . . .. .. |. ..|. . .. ... .|.. YEILRKIGKGAFGKVYKCRHKK---------------TGRIVAIKIIK-------EHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFD VLQTQVASGTR--FSESTIWRLAYGILKALAFMHTPSSSVQKLTGQYCFVHGHITPDTVFLSTNQMPRIGSLHCCTLTSCCLPNAETGGRFKPYLPLDID ... . |.| |.| ......| |..||...| . ..| . |. ..|.. |. ... . YIKKRGRHGLRFPFPE-HARFYMYQICCALEYCH-----------SHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------TTFC SSIF---PPLITPGYEP-LVDIWSLGILLLQACA---------VPRGDLRSNYSEEIADFIDKLLVEDDRIRPTATEALQ-------NPKF . . | .. || . .|.||.|..| .. . .. |.| |||.|.|. | . |||| |||| | | GTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | GL50803_11355.AA | STE | 204-259 | 18 | 3e-06 | 18.42 | In-house | 249-359 (359) | Show / Hide |
Range on Protein: 204-259 Range on HMM: 249-359/359 Sequence Identity: 18% (21 aa) VDIWSLGILL-------LQACAVPRG---------------------------DLRS-------------------NYSEEIADFIDKLLVEDDRIRPTA .||||||... . . | . ..|.| |||.| |. | . |||| CDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTA TEALQ--NPKF .. |. | . SQLLKSEHPFI |
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| Kinase | GL50803_11355.AA | NEK | 226-259 | 27 | 8e-06 | 16.94 | In-house | 251-286 (286) | Show / Hide |
Range on Protein: 226-259 Range on HMM: 251-286/286 Sequence Identity: 27% (10 aa) SN--YSEEIADFIDKLLVEDDRIRPTATEALQNPKF |. ||.. ..| ..| | ||.... |..| SHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI |
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| Kinase | GL50803_11355.AA | RAD53 | 229-259 | 41 | 1.2e-05 | 12.18 | In-house | 275-305 (305) | Show / Hide |
Range on Protein: 229-259 Range on HMM: 275-305/305 Sequence Identity: 41% (13 aa) SEEIADFIDKLLVEDDRIRPTATEALQNPKF ||| .|.|...|. | |.|. |||. | . SEEAKDLIKWMLCVDPEKRYTIDEALNHPWM |
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| Kinase | GL50803_11355.AA | Ciliate-E2 | 227-259 | 31 | 9.3e-05 | 12.24 | In-house | 328-365 (365) | Show / Hide |
Range on Protein: 227-259 Range on HMM: 328-365/365 Sequence Identity: 31% (12 aa) NYSEEIADFIDK----LLVEDDRIRPT-ATEALQNPKF . |.| |.| | .|. | |.| . ..|..| | KWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | GL50803_11355.AA | PAKB | 229-259 | 38 | 0.000521 | 10.71 | In-house | 222-252 (252) | Show / Hide |
Range on Protein: 229-259 Range on HMM: 222-252/252 Sequence Identity: 38% (12 aa) SEEIADFIDKLLVEDDRIRPTATEALQNPKF | . .|.|..|| | | || | |. | . SPRLREFLDRMLVRDPNQRWTAQELLRHPFL |
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| Kinase | GL50803_11355.AA | Pkinase | 217-259 | 25 | 0.002044 | 13.16 | Pfam | 228-293 (293) | Show / Hide |
Range on Protein: 217-259 Range on HMM: 228-293/293 Sequence Identity: 25% (17 aa) CAVPRGDLRSNYS-----------------------EEIADFIDKLLVEDDRIRPTATEALQNPKF | . ...|..... || |||...| | ||||...|| | | CRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | GL50803_11355.AA | CAMK | 198-213 | 50 | 0.003514 | 5.3 | In-house | 309-324 (425) | Show / Hide |
Range on Protein: 198-213 Range on HMM: 309-324/425 Sequence Identity: 50% (8 aa) PGYEPLVDIWSLGILL |.| | .|.||.|..| PYYGPKCDMWSCGVIL |
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| Kinase | GL50803_11355.AA | RAD53 | 199-213 | 53 | 0.004007 | 4.57 | In-house | 217-231 (305) | Show / Hide |
Range on Protein: 199-213 Range on HMM: 217-231/305 Sequence Identity: 53% (8 aa) GYEPLVDIWSLGILL || . ||.||.| .| GYTKKVDCWSMGCIL |
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| Kinase | GL50803_11355.AA | PAKB | 200-214 | 60 | 0.004203 | 7.39 | In-house | 172-186 (252) | Show / Hide |
Range on Protein: 200-214 Range on HMM: 172-186/252 Sequence Identity: 60% (9 aa) YEPLVDIWSLGILLL |.. ||||||||... YGTEVDIWSLGIMVI |
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| Kinase | GL50803_11355.AA | NEK | 98-122 | 36 | 0.007688 | 6.3 | In-house | 107-131 (286) | Show / Hide |
Range on Protein: 98-122 Range on HMM: 107-131/286 Sequence Identity: 36% (9 aa) SGTRFSESTIWRLAYGILKALAFMH .|. |.|..||. . ...|| .|| KGKYFEEEQIWDWFIQMCLALKYMH |
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| Kinase | GL50803_11355.AA | Ciliate-E2 | 199-213 | 60 | 0.008448 | 5.42 | In-house | 272-286 (365) | Show / Hide |
Range on Protein: 199-213 Range on HMM: 272-286/365 Sequence Identity: 60% (9 aa) GYEPLVDIWSLGILL || .||||||..| GYDYKCDIWSLGVIL |
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| Kinase | GL50803_11355.AA | STE | 85-122 | 26 | 0.053036 | 3.01 | In-house | 121-169 (359) | Show / Hide |
Range on Protein: 85-122 Range on HMM: 121-169/359 Sequence Identity: 26% (13 aa) GTSLRSVLQ-TQVASG---------TRFSESTIWRLAYGILKA-LAFMH | ||..... . . .||.|| | . .. |||. |.. | GGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLH |
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| Kinase | GL50803_11355.AA | Pkinase | 198-213 | 50 | 0.322083 | 5.39 | Pfam | 187-202 (293) | Show / Hide |
Range on Protein: 198-213 Range on HMM: 187-202/293 Sequence Identity: 50% (8 aa) PGYEPLVDIWSLGILL ..| | ||.||.|..| QYYGPKVDMWSCGCIL |
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| Pkinase | GL50803_11355.AA | Pkinase | 83-122 | 23 | 0.355133 | 5.24 | Pfam | 81-125 (293) | Show / Hide |
Range on Protein: 83-122 Range on HMM: 81-125/293 Sequence Identity: 23% (11 aa) YVGT-----SLRSVLQTQVASGTRF--SESTIWRLAYGILKALAFMH |.. .| ....| ....| || .. . .| ||..|...| YCEGGLYVMDLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCH |
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| Ank | GL50803_11355.AA | Ank | 374-394 | 33 | 0.004928 | 15.2 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 374-394 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) AGMSALMLAAIYNQAEMVHLL |...|.||......|.| .| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_11355.AA | Ank | 509-541 | 33 | 0.001012 | 17.68 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 509-541 Range on HMM: 1-33/33 Sequence Identity: 33% (11 aa) VGETCLHKAARLGYAKIVEILAPYEANIACRDS |.|.|| |.| |....|. | . |.. .| DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_11355.AA | Ank | 586-605 | 20 | 13.678185 | 2.78 | Pfam | 1-20 (33) | Show / Hide |
Range on Protein: 586-605 Range on HMM: 1-20/33 Sequence Identity: 20% (4 aa) KKTTPLIAAVLSKDINIIRL ||| |... ....... DGFTPLHLACRCGHTEVVKM |
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| Ank | GL50803_11355.AA | Ank | 617-637 | 33 | 0.011593 | 13.86 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 617-637 Range on HMM: 1-21/33 Sequence Identity: 33% (7 aa) DGYTALMHAVLTNQLSAVILL ||.|.|. |.. .... | .| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_11355.AA | Ank | 651-671 | 38 | 0.205061 | 9.36 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 651-671 Range on HMM: 1-21/33 Sequence Identity: 38% (8 aa) EGLTSLWLAYLQGNSAIVRLL .| | | || . |. .|..| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_11355.AA | Ank | 991-1016 | 30 | 0.00238 | 16.34 | Pfam | 1-25 (33) | Show / Hide |
Range on Protein: 991-1016 Range on HMM: 1-25/33 Sequence Identity: 30% (8 aa) NGTTALMLAVAMNSLTLVRLLVGEKG .| |.|.||. .... |..|.. .| DGFTPLHLACRCGHTEVVKMLLQ-HG |
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| Ank | GL50803_11355.AA | Ank | 1094-1113 | 40 | 45.363277 | 0.9 | Pfam | 4-23 (33) | Show / Hide |
Range on Protein: 1094-1113 Range on HMM: 4-23/33 Sequence Identity: 40% (8 aa) TALGFAAYRGATRIVQSLLG |.| |...| |..|. ||. TPLHLACRCGHTEVVKMLLQ |
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| Ank | GL50803_11355.AA | Ank | 1123-1144 | 45 | 0.000177 | 20.41 | Pfam | 1-22 (33) | Show / Hide |
Range on Protein: 1123-1144 Range on HMM: 1-22/33 Sequence Identity: 45% (10 aa) NHRTPLMLAAITGHLATIKLLL . .|||.||.. ||. .|.|| DGFTPLHLACRCGHTEVVKMLL |
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| Ank | GL50803_11355.AA | Ank | 1154-1186 | 33 | 0.000381 | 19.21 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 1154-1186 Range on HMM: 1-33/33 Sequence Identity: 33% (11 aa) DGYTALAIATYHGHSDVVEFLFPYEAHICTKTG ||.|.| .| ..|| .||..| . | .. .. DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_11355.AA | Ank | 1294-1314 | 47 | 8.4e-05 | 21.57 | Pfam | 1-21 (33) | Show / Hide |
Range on Protein: 1294-1314 Range on HMM: 1-21/33 Sequence Identity: 47% (10 aa) CGRTALMIAAACNHTACVQML .|.|.|..|. |.|| .|.|| DGFTPLHLACRCGHTEVVKML |
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| Ank | GL50803_11355.AA | Ank | 1261-1293 | 24 | 0.02852 | 12.45 | Pfam | 1-33 (33) | Show / Hide |
Range on Protein: 1261-1293 Range on HMM: 1-33/33 Sequence Identity: 24% (8 aa) QGTTLLMYCCKRNLHSFVDVLVRRKKGLGLQDH | | |.. |... .. | |. . . .|| DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD |
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| Ank | GL50803_11355.AA | Ank | 1325-1350 | 30 | 10.005448 | 3.27 | Pfam | 1-25 (33) | Show / Hide |
Range on Protein: 1325-1350 Range on HMM: 1-25/33 Sequence Identity: 30% (8 aa) YRTTALISATKSGAYEAAELLLDEAG . |.| | ..| .| ...||. .| DGFTPLHLACRCGHTEVVKMLLQ-HG |
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| Ank | GL50803_11355.AA | Ank | 1355-1384 | 20 | 37.949519 | 1.18 | Pfam | 1-29 (33) | Show / Hide |
Range on Protein: 1355-1384 Range on HMM: 1-29/33 Sequence Identity: 20% (6 aa) GDYTALYYAVGECHNDRLIELLLPYEASIC .|.| .|. . . ...|| . |... DGFTPLHLACRCG-HTEVVKMLLQHGADVN |
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