Gene GL50803_15548 (G.lamblia)
GL50803_15548
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_15548.AA | Protein | None | 1066 | None | Fasta, JSON |
| GL50803_15548.kin_dom | Protein Kinase Domain | None | 315 | None | Fasta, JSON |
Protein domains of GL50803_15548.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | GL50803_15548.AA | Trio | 794-888 | 26 | 1.4e-09 | 20.07 | In-house | 93-191 (258) | Show / Hide |
Range on Protein: 794-888 Range on HMM: 93-191/258 Sequence Identity: 26% (27 aa) SERRIRVFIRSLLQAINFLYSNDTKLIHRDLRPNQIWVKKNSNGDPVAKIYHMGFMYPLSAN--EPMEHNTI---WVAPEVVCG-GIDTKSDIWSVGTLT .|. ...... .|.|.. | .. .| |..| . . . | | || |. .|. || .| . .|||.. | ... .||||.| || CESEVKTYMWQMLEAVHYLHNC--HILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQLWPHKVEPQHHQYGNPEFMAPEIIQGNPVSYGTDIWSIGVLT F . Y |
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| S_TKc | GL50803_15548.AA | S_TKc | 661-1055 | 12 | 1.6e-09 | -37.27 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 661-1055
Range on HMM: 1-231/231
Sequence Identity: 12% (51 aa)
YDAGLK-------SVMAAICTTFPPVAVIKNRFIILPQKTKITAGYGFSTKMPKTNSFNVMLPAWDLLQHTVLSAKIFPMTLSGKQFLRVYRQLSHRGIL
|. . | .|. .. . . || .... | |. | |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------------------------------------EHIRREIQILKK----HHPNIV
SFVGCGTAINNAFYVFTESPPK--IKLSRVFQYDEE-ALQLFRSERRIRVFIRSLLQAINFLYSNDTKLIHRDLRPNQIWVKKNSNGDPVAKIYHMGFMY
. .. . .|...| . | .. . |. .| ..| ... ...|.... |. . ||||| | | . . . || |.
KLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE------HIKICDFGLAR
PLSANEPMEHNTIWVAPEVVCGGIDT-KSDIWSVGTLTFRLLETLVNLHQGRRGHNLNNLFCPSFADISKVPSFAPGSGERSLLVANNSSVIYQMMLMSS
| . ..||||. | .. |.|.||.| . . .| . . ... .|
QL---TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLC-GYPPFP-----QMQMMFKKIG-----------------------------------
DKVEVAPNRYAVYTVKNCDAAIEKAKVPWSMRRAYFASTGILPWYDLNYAKPGAQKEECGNLDTFFETAIYSQIISANAVDFIKRCWTFNLDLRWSPELM
| | |||..|.... . |..
---------------------------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA
LT-------HPWL
|. |||.
LQDEWDIKCHPWF
|
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| Kinase | GL50803_15548.AA | CAMK-Tt | 1024-1055 | 50 | 4.8e-09 | 26.85 | In-house | 365-396 (396) | Show / Hide |
Range on Protein: 1024-1055 Range on HMM: 365-396/396 Sequence Identity: 50% (16 aa) ISANAVDFIKRCWTFNLDLRWSPELMLTHPWL || .| | ||.| | | . | |. || |||. ISEEAKDLIKKCLTINPEQRIKPDQMLQHPWI |
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| Kinase | GL50803_15548.AA | STE | 1020-1055 | 26 | 5.6e-08 | 24.38 | In-house | 322-359 (359) | Show / Hide |
Range on Protein: 1020-1055 Range on HMM: 322-359/359 Sequence Identity: 26% (10 aa) YSQIISANAVDFIKRCWTFNLDLRWSPELMLT--HPWL |. | . |||..| . . . |.... .| ||.. YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | GL50803_15548.AA | CMGC | 1014-1055 | 21 | 8.8e-07 | 17.32 | In-house | 460-513 (513) | Show / Hide |
Range on Protein: 1014-1055 Range on HMM: 460-513/513 Sequence Identity: 21% (12 aa) FFETAIYSQ---------------IISANAVDFIKRCWTFNLDLRWSPELMLTHPWL | . || . .. |.|..|.. ... | |...| | ||.. F-NW-IY-EEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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| Kinase | GL50803_15548.AA | CDK4 | 1021-1055 | 20 | 4e-06 | 16.89 | In-house | 256-290 (290) | Show / Hide |
Range on Protein: 1021-1055 Range on HMM: 256-290/290 Sequence Identity: 20% (7 aa) SQIISANAVDFIKRCWTFNLDLRWSPELMLTHPWL .. .. . |..... ..|...| | . | ||.. CPHMCKQGDDLLQKMLCYNHHKRMSAYQCLQHPYF |
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| Kinase | GL50803_15548.AA | Ciliate-E2-Unclassified | 866-891 | 41 | 6e-06 | 16.68 | In-house | 234-264 (352) | Show / Hide |
Range on Protein: 866-891 Range on HMM: 234-264/352 Sequence Identity: 41% (13 aa) APEVVCG-GID----TKSDIWSVGTLTFRLL |||| .| . | |.||||.| . . .| APEVLQGQNYDHSKAYKCDIWSLGVILYEML |
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| Kinase | GL50803_15548.AA | CAMK-Unique | 1015-1055 | 37 | 8e-06 | 14.96 | In-house | 321-363 (363) | Show / Hide |
Range on Protein: 1015-1055 Range on HMM: 321-363/363 Sequence Identity: 37% (16 aa) FETAIYSQI--ISANAVDFIKRCWTFNLDLRWSPELMLTHPWL |.. .. || .| ||.|.| | .| ||| . | |.|. FDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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| Kinase | GL50803_15548.AA | STE | 864-884 | 50 | 1.2e-05 | 16.06 | In-house | 228-255 (359) | Show / Hide |
Range on Protein: 864-884 Range on HMM: 228-255/359 Sequence Identity: 50% (14 aa) WVAPEVVCG-------GIDTKSDIWSVG | ||||. . | |||.||||.| WMAPEVIQQNGQGRDKGYDTKCDIWSLG |
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| Kinase | GL50803_15548.AA | STE20 | 1025-1055 | 25 | 1.9e-05 | 16.24 | In-house | 258-288 (288) | Show / Hide |
Range on Protein: 1025-1055 Range on HMM: 258-288/288 Sequence Identity: 25% (8 aa) SANAVDFIKRCWTFNLDLRWSPELMLTHPWL | . ||...| . . . |.... .|.||.. SPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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| Kinase | GL50803_15548.AA | DYRK | 1029-1055 | 40 | 2e-05 | 16.59 | In-house | 294-320 (320) | Show / Hide |
Range on Protein: 1029-1055 Range on HMM: 294-320/320 Sequence Identity: 40% (11 aa) VDFIKRCWTFNLDLRWSPELMLTHPWL .||||.| ... . |..|. | |||. KDFIKKCLQWDPHKRITPSQALQHPWF |
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| Kinase | GL50803_15548.AA | CAMK | 1024-1055 | 25 | 3e-05 | 12.09 | In-house | 386-425 (425) | Show / Hide |
Range on Protein: 1024-1055 Range on HMM: 386-425/425 Sequence Identity: 25% (10 aa) ISAN--------AVDFIKRCWTFNLDLRWSPELMLTHPWL || . . |.|... . . . |.. | | |||. ISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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| Kinase | GL50803_15548.AA | Pkinase | 1024-1055 | 37 | 4.9e-05 | 18.89 | Pfam | 262-293 (293) | Show / Hide |
Range on Protein: 1024-1055 Range on HMM: 262-293/293 Sequence Identity: 37% (12 aa) ISANAVDFIKRCWTFNLDLRWSPELMLTHPWL .| .. ||||.|.... |...| | |||. WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | GL50803_15548.AA | STE20 | 864-884 | 48 | 5.2e-05 | 14.58 | In-house | 188-214 (288) | Show / Hide |
Range on Protein: 864-884 Range on HMM: 188-214/288 Sequence Identity: 48% (13 aa) WVAPEVVCG------GIDTKSDIWSVG | ||||... | |.|.||||.| WMAPEVIQCMEGPDKGYDYKCDIWSLG |
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| Kinase | GL50803_15548.AA | CMGC | 796-826 | 27 | 6.4e-05 | 11.08 | In-house | 170-212 (513) | Show / Hide |
Range on Protein: 796-826 Range on HMM: 170-212/513 Sequence Identity: 27% (12 aa) RR----IRVFI------RSLLQAIN--FLYSNDTKLIHRDLRP || |. |. . .|.... .. |.. . ||||| | RRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKP |
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| Kinase | GL50803_15548.AA | DYRK | 796-826 | 35 | 0.000136 | 13.4 | In-house | 103-132 (320) | Show / Hide |
Range on Protein: 796-826 Range on HMM: 103-132/320 Sequence Identity: 35% (11 aa) RRIRVFIRSLLQAINFLYSNDTKLIHRDLRP ...|.|....|... ||..| ..|| || | NLVRKFAQQILTCLKFLHKNE-NIIHCDLKP |
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| Kinase | GL50803_15548.AA | CAMK | 865-888 | 25 | 0.000226 | 9.21 | In-house | 286-325 (425) | Show / Hide |
Range on Protein: 865-888 Range on HMM: 286-325/425 Sequence Identity: 25% (10 aa) VA-PEVVCG---------------GIDTKSDIWSVGTLTF .| |||. | ... |.|.||.| ... MAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILY |
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| Kinase | GL50803_15548.AA | Ciliate-E2-Unclassified | 1021-1055 | 30 | 0.000675 | 9.43 | In-house | 314-352 (352) | Show / Hide |
Range on Protein: 1021-1055 Range on HMM: 314-352/352 Sequence Identity: 30% (12 aa) SQIISANAVDFIK----RCWTFNLDLRWSPELMLTHPWL ....| .| |||. .. |.. | ..| | |||. PKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | GL50803_15548.AA | CAMK-Unique | 865-892 | 23 | 0.001157 | 7.74 | In-house | 242-288 (363) | Show / Hide |
Range on Protein: 865-892 Range on HMM: 242-288/363 Sequence Identity: 23% (11 aa) VAP--------------EVVC-GGIDTKS----DIWSVGTLTFRLLE .|| ||. ..| .. |||| | ... .|. MAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLC |
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| Kinase | GL50803_15548.AA | Pkinase | 794-824 | 29 | 0.001515 | 13.62 | Pfam | 106-134 (293) | Show / Hide |
Range on Protein: 794-824 Range on HMM: 106-134/293 Sequence Identity: 29% (9 aa) SERRIRVFIRSLLQAINFLYSNDTKLIHRDL ||. .. ... .|.......|. . ||||| SEWECKFYMYQILRGLEYCHSM--GIIHRDL |
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| Kinase | GL50803_15548.AA | CAMK | 794-826 | 33 | 0.003185 | 5.44 | In-house | 177-207 (425) | Show / Hide |
Range on Protein: 794-826 Range on HMM: 177-207/425 Sequence Identity: 33% (11 aa) SERRIRVFIRSLLQAINFLYSNDTKLIHRDLRP .|| | ..| ...|.... |.. .|||| | TEREARRYFRQICSAVHYCHSHN--IVHRDLKP |
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| Kinase | GL50803_15548.AA | CDK4 | 794-831 | 36 | 0.003603 | 6.48 | In-house | 108-143 (290) | Show / Hide |
Range on Protein: 794-831 Range on HMM: 108-143/290 Sequence Identity: 36% (14 aa) SERRIRVFIRSLLQAINFLYSNDTKLIHRDLRPNQIWV .. |. . || .. || |. ||||| | | | PPCTIKHMMHQLLRGVDFLHSH--RIIHRDLKPQNILV |
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| Kinase | GL50803_15548.AA | Ciliate-E2-Unclassified | 794-827 | 23 | 0.003651 | 6.85 | In-house | 136-173 (352) | Show / Hide |
Range on Protein: 794-827 Range on HMM: 136-173/352 Sequence Identity: 23% (9 aa) SERRIR-----VFIRSLLQAINFLYSNDTKLIHRDLRPN .|. .. ... .||....| .. . ||||. |. TEQQAKYKKAKFYFAQILQGLEYLHHKN-NIIHRDIKPE |
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| Kinase | GL50803_15548.AA | CMGC | 866-884 | 33 | 0.011063 | 3.6 | In-house | 293-322 (513) | Show / Hide |
Range on Protein: 866-884 Range on HMM: 293-322/513 Sequence Identity: 33% (10 aa) APEVVCGGI-----------DTKSDIWSVG |||. .| .|. |.|||| APEILLGWKHYTNHNYSMHYTTPIDMWSVG |
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| Kinase | GL50803_15548.AA | CAMK-Unique | 794-824 | 33 | 0.015714 | 3.94 | In-house | 153-183 (363) | Show / Hide |
Range on Protein: 794-824 Range on HMM: 153-183/363 Sequence Identity: 33% (11 aa) SE--RRIRVFIRSLLQAINFLYSNDTKLIHRDL || . .. ...||.|.... |.| .|||| SERCWDTCFIMQCLLSAVAYMHSQD--IVHRDL |
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| Kinase | GL50803_15548.AA | Trio | 1024-1055 | 31 | 0.038008 | 0.58 | In-house | 227-258 (258) | Show / Hide |
Range on Protein: 1024-1055 Range on HMM: 227-258/258 Sequence Identity: 31% (10 aa) ISANAVDFIKRCWTFNLDLRWSPELMLTHPWL .| ||..||. | . . | |||. VSQNAKHFICKVLQEDPWKRPCASECLQHPWF |
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| Kinase | GL50803_15548.AA | Pkinase | 864-884 | 39 | 0.042779 | 8.49 | Pfam | 177-199 (293) | Show / Hide |
Range on Protein: 864-884 Range on HMM: 177-199/293 Sequence Identity: 39% (9 aa) WVAPEV-V-CGGIDTKSDIWSVG ..|||| . ....|.|.||.| YMAPEVIRGGQYYGPKVDMWSCG |
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| Kinase | GL50803_15548.AA | STE | 794-826 | 32 | 0.078537 | 2.4 | In-house | 149-180 (359) | Show / Hide |
Range on Protein: 794-826 Range on HMM: 149-180/359 Sequence Identity: 32% (11 aa) SERRIRVFIRSLLQA-INFLYSNDTKLIHRDLRP .| |....|..|.. ..| |. ||||. | PESQIAYICRQILKGLLYYLHSHH--IIHRDIKP |
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