Gene GL50803_16796 (G.lamblia)

GL50803_16796

Species: G.lamblia
Alias: GL50803_16796, GK044
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Bud32

Sequence

Name Sequence Type Origin Length Description Download
GL50803_16796.AA Protein None 251 None Fasta, JSON
GL50803_16796.kin_dom Protein Kinase Domain None 219 None Fasta, JSON

Protein domain

Protein domains of GL50803_16796.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_16796.AA Bud32 37-251 30 7.4e-49 154.14 In-house 3-267 (269) Show / Hide 
Range on Protein: 37-251
Range on HMM: 3-267/269
Sequence Identity: 30% (83 aa)

SLLF---------QGAEARIYS------------GTLSTSGK------DAIAKHRFPKEYRHPALDRQIRQRRTRAEARALEAAHAAGLAVPSVLYVDEP
..|          ||||||..              |    |.       .| |.|||| ||||.|| |.  .|| .|.||.  . .||..||.|. .|  
LELYKDVDIAPISQGAEARVFYTCYLTVSKQKVYTTCNFQGRAKDSHQQCIIKERFPKAYRHPQLDQQLTKHRTKQEVRAMNRCRKAGICVPYVYFCDNY

NGCIYMSWIRDS-------SVSTHLA--------DSTDLLFDEAFAKLVGSTIARLHMARIVHNDLTTSNLLYNRDERRL-------SVIDFGLASRSPI
|.||||  | .|        |   .         | .| .  | |.| || .|...|   |.| |||||| . .... ..         ||||| . |  
NHCIYMEYIEESPGGHGFYTVKNYIWQHQETQKEDQHDQCLRE-FCKKVGRQIGKMHWNHIIHGDLTTSNMMLRHPYADWTKLYGQMHLIDFGLSYISNS

TPETMAVDLYVFQRSILALCGPCPF------FETVLKFYVCYMDEHSGDKGQGQKILTQLEQVQGRGRKK
.||  .|||||  | .|     |.       ||.... |     . ..   . .  |. ...|  ||||.
VPEDKGVDLYVLERAFLSTHPKCEQKYNAWIFEHFMENY----RKQDTKCKKFKAVLKKFNEVRLRGRKR
Kinase GL50803_16796.AA TESK 150-196 35 3e-06 15.43 In-house 110-169 (292) Show / Hide 
Range on Protein: 150-196
Range on HMM: 110-169/292
Sequence Identity: 35% (21 aa)

LHMARIVHNDLTTSNLLYN-RDERRLSVI--DFGLA----------SRSPITPETMAVDL
|| . . | |||  | |   ||.. .. .  |||||            || |||.   |.
LHSKGVFHRDLTSKNCLVRQRDNNQYEAVVGDFGLARVLGCMPDPPPNSPRTPESPEPDI
Kinase GL50803_16796.AA CDC7 148-182 42 1e-05 11.47 In-house 122-156 (522) Show / Hide 
Range on Protein: 148-182
Range on HMM: 122-156/522
Sequence Identity: 42% (15 aa)

ARLHMARIVHNDLTTSNLLYNRDERRLSVIDFGLA
...|   |.| |   || |||| ...   .|||||
RHVHQFGIIHRDVKPSNFLYNRRTKKFLLVDFGLA
Kinase GL50803_16796.AA MSK 139-182 30 0.000109 11.77 In-house 107-151 (277) Show / Hide 
Range on Protein: 139-182
Range on HMM: 107-151/277
Sequence Identity: 30% (14 aa)

FAKLVGSTIARLHMARIVHNDLTTSNLLYNRD--ERRLSVIDFGLA
...|| . .  .|  .|.| ||   |.|.  .  .... .||||.|
MRELV-MAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFA
Kinase GL50803_16796.AA RSK 150-182 37 0.000112 13.44 In-house 120-154 (278) Show / Hide 
Range on Protein: 150-182
Range on HMM: 120-154/278
Sequence Identity: 37% (13 aa)

LHMARIVHNDLTTSNLLYNR--DERRLSVIDFGLA
||   |.| ||  .| ||.   .|... ..|||..
LHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFC
Kinase GL50803_16796.AA CMGC 150-182 25 0.000117 10.21 In-house 198-251 (513) Show / Hide 
Range on Protein: 150-182
Range on HMM: 198-251/513
Sequence Identity: 25% (14 aa)

LHMAR--IVHNDLTTSNLLYNRDERR-------------------LSVIDFGLA
.| ..  |.| ||  .|.| | . .                    | ..|||||
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase GL50803_16796.AA PSK 150-183 47 0.000136 10.24 In-house 112-147 (258) Show / Hide 
Range on Protein: 150-183
Range on HMM: 112-147/258
Sequence Identity: 47% (17 aa)

LHMARIVHNDLTTSNLLY--NRDERRLSVIDFGLAS
||  || | ||   ||||   ..| .. . |||||.
LHALRITHRDLKPENLLYYHPGNESKIMITDFGLAY
Kinase GL50803_16796.AA CK2 151-182 37 0.000184 8.4 In-house 112-143 (288) Show / Hide 
Range on Protein: 151-182
Range on HMM: 112-143/288
Sequence Identity: 37% (12 aa)

HMARIVHNDLTTSNLLYNRDERRLSVIDFGLA
|   |.| |   .| . .  .|.|..|| |||
HSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLA
Kinase GL50803_16796.AA Ciliate-E2 150-193 18 0.000217 10.96 In-house 176-255 (365) Show / Hide 
Range on Protein: 150-193
Range on HMM: 176-255/365
Sequence Identity: 18% (16 aa)

LHMAR-IVHNDLTTSNLLYNRDERRLSVIDFGLASRSPI-----------------------------------------TPETMA
||    |.| |.  .|.|.      . .|||||. .  .                                         ||. ||
LHSKNNIIHRDIKPENILF------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMA
Kinase GL50803_16796.AA GIN4 151-182 40 0.000269 9.16 In-house 151-182 (293) Show / Hide 
Range on Protein: 151-182
Range on HMM: 151-182/293
Sequence Identity: 40% (13 aa)

HMARIVHNDLTTSNLLYNRDERRLSVIDFGLA
|   |.| ||   |||  .  .|. . |||.|
HAFNICHRDLKPENLLLDHKYNRIKIADFGMA
S_TKc GL50803_16796.AA S_TKc 33-244 14 0.000435 -116.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-244
Range on HMM: 1-231/231
Sequence Identity: 14% (38 aa)

LDNCSLLFQGAEARIYSGTLSTSGKDAIAKHRFPKEYRHPALDRQIRQRRTRAEARALEAAHAAGLAVPSVLYVDE-PNGCIYMSWIRD--SSVSTHLAD
 .   .. .|| .. | ..   .|.    |                  ...| | . |.        .   ..| .  . .. |  .     .. ... .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK---HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKK

STD----LLFDEAFAKLVGSTIAR----LHMARIVHNDLTTSNLLYNRDERRLSVIDFGLASR---SPITPETMAVDLYVFQRSILA-------------
         |.|  |. .   |..    .|  .|.| ||  .|.| ..   .. ..||||| .      ||. ||  .     .                
RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQLTTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILY

--LCGPCPFFETVLKFYVCYMDEHSGDKGQGQ----KILT------------Q-------LEQV
  |||  ||  .. . .   .        ..     |.|.            |        . .
EMLCGYPPFP-QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF