Gene GL50803_16834 (G.lamblia)

GL50803_16834

Species: G.lamblia
Alias: GK077, GL50803_16834
External Links: GiardiaDB ,
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: CDC15

Sequence

Name Sequence Type Origin Length Description Download
GL50803_16834.AA Protein None 1837 None Fasta, JSON
GL50803_16834.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of GL50803_16834.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_16834.AA STE11 13-267 36 2.8e-99 336.11 In-house 1-303 (303) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-303/303
Sequence Identity: 36% (112 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKKK--AVDQGFIKE------VMSEINLLSKLNHSNIVKYRGCFL---EQNYLYIILELVDFGSL
...  .|||||| .| |. .  || ..| || | .. ..  . .. ....       ..||.|...||| |||.| || |   ......|..| .  |||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

QTLIK-QYDD--LGENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGL-CKLTDFGLSQRLQ-DVDPTVV-----------EGSPY--------
  ...  .    . |.|.  |. ||| ||.|||..||||.|||.||||. | |  |||.||| . ||. .   |              |.||        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WLAPEVINEEG---VSTKSDVWSLGATMIELLTKKPPFHNLTG--FAAMYNIATL--TEMPLPPNIS------PECADFLSCCFKIDPHERHSCAELLNH
| |||||..||    ..|.|.||||.|.|| .| |||.||..   .|||. |..   .  |.| ..|      .|| |||. ||..||..| . ..||.|
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PWL
|..
PFI
Kinase GL50803_16834.AA Dicty2 13-267 47 1.8e-98 333.42 In-house 1-264 (264) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-264/264
Sequence Identity: 47% (126 aa)

YTLH-CLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKKKAVDQGFIKEVMSEINLLSKLNHSNIVKYRGCFLEQNYLYIILELVDFGSLQTLIKQYDDL
|..    ||||||..| |. .  || ||| || .   ||.  .   .. .| ||.|| |||| ||||| .    .|.|||||| .  ||| . || .  .
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCF

GENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGL---CKLTDFGLSQRLQ----DVDPTVVEGSPYWLAPEVINEEG--VSTKSDVWSLGATM
 |  .  ||||.| || |||.||.|| |||||||| |  |     ||.|||    .     | . ||| | ||| |||||   |   .|..|.|||| |.
PESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVV-GTPYWMAPEVIQMSGNHCCTACDIWSLGCTI

IELLTKKPPFHNLTGFAAMYNIATLTEMPLPPNISPECADFLSCCFKIDPHERHSCAELLNHPWL
|||||  ||   |   .||. .      |||..|||||.|||  ||. || .| .  .||.|||.
IELLTGNPPYWDLNPMHAMFRMVQDDHPPLPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase GL50803_16834.AA S_TKc 13-267 32 6.7e-94 319.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKKKAVDQGFIKEVMSEINLLSKLNHSNIVKYRGCFLEQNYLYIILELVDF--GSLQTLIKQYDD
|... .||||||.||.|. .  ||  ||.|..              . ...||..|.| .| ||||. ..| . ..||...|..|   |.| ..||..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

------LGENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLSQRLQDVDPTVVEGSPYWLAPEVINEEGVST-KSDVWSLGATMI
      . | ....|.|||...|.|.|..|||| |.| .|||...    |..||||. .|     | . |.|...||||.   | .. |.|.||.| ...
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELLTKKPPFHNLTGFAAMYNIATLTEMPLPPNISPECADFLSCCFKIDPHERHSCAELLN-------HPWL
|.|. .|||.     ..|...            |||. ||.. |.. || .| .. |.|.       |||.
EMLCGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase GL50803_16834.AA STE 13-267 28 2.5e-93 316.34 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-359/359
Sequence Identity: 28% (106 aa)

YTLHCLIGKGAFAKVWKAADEV---------------TGGFVALKQLEPKGKKKAVDQ------------GFIKEVMSEINLLSKLN--HSNIVKYRGCF
...   |||||| .| ||..                 || ..| ||.. . ... . .              ..... ||....|.|  | ||||| ||.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

LEQ-------NYLYIILELVDFGSLQTLIK-QYDDLG-------------ENVVACYIYQILLG-LKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLS
.         ..|.|..|..| |||  .||  |  ..             |...|....||| | |.|||...||| |||.||||.     .||.|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

QRLQD-----------------V-DPTVVEGSPYWLAPEVINE------EGVSTKSDVWSLGATMIELLTKKPPFHNLTGFAAMYNIATL----------
 .|.|                 .   . . |.| | |||||.        | .||.|.|||| |.||..| |||.|... . ||..|..           
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----TEMPLPP-------------------NISPECADFLSCCFKIDPHERHSCAELLN--HPWL
     .  |||.                   . |||. ||.. |...||..| .  .||.  ||..
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase GL50803_16834.AA Pkinase 13-267 29 6.8e-86 296.45 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKKKAVDQGFIKEVMSEINLLSKLNHSNIVKYRGCFLEQNYLYIILELVDFG----SLQTLIK--
|...  ||.|.|..|.|. .  ||  ||.|... ...|. .||  ..   ||| .. .||| |||.....| . ...|...|... |    .| ..|.  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

QYDDL--GENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLC----KLTDFGLSQ---RLQDVDPTVVEGSPYWLAPEVIN-EEGVSTKSDVW
..  .   |... .|.|||| ||.|.|..|||| |.| .|||. . | .    |..||||.       .. .|.. |.|...|||||.  .. ..|.|.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGATMIELLTKKPPFHNL----TGFAAMYNIATLTEMPLPPNIS-----------------------PECADFLSCCFKIDPHERHSCAELLNHPWL
|.| ...|.|...||| .     .    |. |.   . ||. ...                       .|| ||...|.. ||..| .....|.|||.
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase GL50803_16834.AA STE20 13-267 33 9.7e-82 277.87 In-house 1-288 (288) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-288/288
Sequence Identity: 33% (97 aa)

YTLHCLIGKGAFAKVWKAADEVTGGF----VALKQLEPKGK---KKAVDQGFIKEVMSEINLLSKLNHSNIVKYRGCFLEQ----NYLYIILELVDFGSL
|.|   ||.|.. || || .  ||      || |... . .   .       ..... ||. .....| ||||| |..|      . |.|. |. . |||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-----DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSL

QTLIKQYDDLG---------ENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLSQRLQD-----VD-P-TVVEGSPYWLAPEVIN
. ..|..  .|         |  .|.  ...| ||.|||...||| ||||.|||.|..| .||.|||... |..      . .   . |.|||.|||||.
TDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQ

E-----EGVSTKSDVWSLGATMIELLTKKPPFHNLTGFAAMYNIATLTEMPL------PPNISPECADFLSCCFKIDPHERHSCAELLNHPWL
.      |  .|.|.|||| | ||... .||....  . ||. |.. .. |.      | . |||  ||.. |  .||..| .  .||.||..
CMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase GL50803_16834.AA STE11-Unclassified 13-267 34 4.2e-79 269.1 In-house 1-308 (308) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-308/308
Sequence Identity: 34% (106 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKK---KAVDQGFIKEVMSEINLLSKLNHSNIVKYRGCF--LEQNYLYIILELVDFGSLQTLIKQ
.    .||||.| .| |. .  || |.| ||.| ....   ... .  |.   .|...| .||| |||.| ||    ... ..|..| .  ||.  ... 
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

YDDLGENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLSQ-------------------RLQDVDPT--------VVEGSPY---
|  . |.| . |  ||| ||.|||..||||.|||.||||  . | |||||||..                      ... ..           |.||   
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

WLAPEVIN---EEGVSTKSDVWSLGATMIELLTKKPPFHNLTG---FAAMYNIATLTEMPLPPN------------ISPECADFLSCCFKIDPHERHSCA
| |||||.   ..| ..|||.|||| |.||  | |.|. |..     .|.. |.   . |  |.            ||.|| |||. ||.|||..| .  
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTAN

ELLNHPWL
.||.||..
QLLQHPFI
Kinase GL50803_16834.AA ULK 13-267 28 1.5e-68 234.03 In-house 1-324 (324) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-324/324
Sequence Identity: 28% (93 aa)

YTLHCLIGKGAFA-KVWKAADEVT---GGFVALKQLE-PKGKKKAVD---QGFIKEVMSEINLLSKLN---HSN--IVKYRGCFLEQ--NYLYIILELVD
| |.  .|||.|. || |. .. |   . .|| |. .  | .||  .   | ...  ..||... ||.   | |  |||.  .| ..  |..|||.|. .
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

FGSLQTLIKQYDDLGENV----------VACYIYQILLGLKYLHEQGIIHKDIKAANILMTS------------SGLCKLTDFGLSQRLQ------DVDP
 | |...||..  |.| .          .  ...||. |.|.||...||| ||| .|||..             .| .|..|||... ..      ..  
GGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

TVVE-----GSPYWLAPEVIN----EEGVS-TKSDVWSLGATMIELLTKKPP----FHNLT----GFAAM------YNIATLTEMPLPP---NISPECAD
| |      |.|.  ||....    ..  .  |.|.||||  . |.|. |.|    | ..         .      |   .  . |.||   .||||| |
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

FLSCCFKIDPHERHSCAELLNHPWL
........|. .| |  |..||||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase GL50803_16834.AA MEKK2 13-267 40 3.4e-65 222.9 In-house 1-262 (262) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-262/262
Sequence Identity: 40% (107 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKKKAVDQGFIKEVMSEINLLSKLNHSNIVKYRGCFLEQN--YLYIILELVDFGSLQTLIKQYDD
. .  |.|.||| .|.   |  ||  .| || .   .     .  .. .  ||.||  | |  ||.| ||  ...   | | .| .  ||..  .| |  
WRRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKE-VQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGGSVKDQLKAYGA

LGENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLSQRLQDVDPTV-----VEGSPYWLAPEVINEEGVSTKSDVWSLGATMIEL
| |.|   |  ||| |..|||.. |.|.||| ||||  |||  || ||| |.||| .   .     | | |||..||||| ||   | ||||.| |..|.
LTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTICMHITGMKSVTGTPYWMSPEVINGEGYGRKADVWSIGCTVVEM

LTKKPPFHNLTGFAAMYNIATL-TEMPLPPNISPECADFLSCCFKIDPHERHSCAELLNHPWL
||.|||. .    ||.. |||  |.  ||. .| .  |||  ||.    .| | .||| | . 
LTEKPPWAEYEAMAAIFKIATQPTNPQLPQHVSQHARDFLKRCFVEIKQDRPSAEELLRHHFV
Kinase GL50803_16834.AA ULK 13-267 28 9.2e-65 221.47 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-329/329
Sequence Identity: 28% (94 aa)

YTLHCLIGKGAFAKVWKAADEVT----GGFVALKQLEPK-GKKKAVD---QGFIKEVMSEINLLSKLN--------HSNIVKYRGCFLEQ--NYLYIILE
| |.  .|||.|.|| |. .. |    .  || |... .  ..|  .   | ... ...|| .. ||.        | ||||.  .| ..  |..|||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LVDFGSLQTLIKQYDDLGENV----------VACYIYQILLGLKYLHEQGIIHKDIKAANILMTSS------------GLCKLTDFGLSQRLQ-D-----
. . | |...||..  |.|..          .  ...||| |.|.||...||| ||| .|||..              | .|..|||... .. |     
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

VDPTVV--E---GSPYWLAPEVIN----EEGVS-TKSDVWSLGATMIELLTKKPP----FHNLTGFAAMYNIA-----------TLTEMPLP---PNISP
.  | |  .   |.|.  ||....    ..  .  |.|.||||  . |.|. |||    |  .     . .|            . .. | .   |.|||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

ECADFLSCCFKIDPHERHSCAELLNHPWL
|| |........|. .| |  ||.||||.
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase GL50803_16834.AA MEKK15 13-267 37 9.4e-64 218.12 In-house 1-264 (264) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-264/264
Sequence Identity: 37% (101 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLE-PKGKKKAVDQGFIKEVMSEINLLSKLNHSNIVKYRGCFLEQNYLYIILELVDFGSLQTLIKQYDDL
..   ..||||.  |.    . ||  .| || |  .  |.. .| . | .  |..||  | | ||| | |  ||.| . | .. |  ||.  .|  .  |
WKKGNILGKGAYGTVYCGLTN-TGQLIAVKQVELDEIDKEKAKQQYRK-LQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSISSIINRFGPL

GENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLSQRL--QDVDPTV------VEGSPYWLAPEVINEEGVSTKSDVWSLGATMI
 | |   |  ||| | .||||  ..|.||| .|... . |. || |||  .||  | .. |       . | |||.|||||.| |   |||.||.| |. 
DEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLCWQGINRTHSDMLKSMRGTPYWMAPEVIMETGYGRKSDIWSIGCTVF

ELLTKKPPFHNLTGFAAMYNIATL-TEMP-LPPNISPECADFLSCCFKIDPHERHSCAELLNHPWL
|. |.|||. ..   |||. | .    || ||   | . ..|   |   | ||| .  .|| ||..
EMATRKPPWADMDRMAAMFYIGAHRDPMPQLPVKFSEDARMFVRMCLTRDQHERPTASQLLKHPFI
Kinase GL50803_16834.AA Ciliate-E2-Unclassified 13-267 22 3.2e-60 206.37 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-352/352
Sequence Identity: 22% (81 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKKKAVDQGFIKEVMSEINLLSKLN-----------------HSNIVKYRGCFLE--QNYLYIIL
|...  ||.|.|.||.|. .. .. . |.|..  . ..|   . . .| | |.. . ...                 | ...... .. .  ....||..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELVDFGSLQTLIKQYDD-----------------LGENVVA-----CYIYQILLGLKYLHEQG-IIHKDIKAANILMTSSG---LCKLTDFGLSQRLQDV
|... |.|.  ||..                   . |. ..      |..|||.||.|||... ||| |||  |||....|    .|..|||.| ..|. 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---DPTV---------------VEGSPYWL----APEVINEEGVS----TKSDVWSLGATMIELLTKKPPFH--NLTG----------------FAAMYN
   | |                . |.|. .    ||||. ... .     |.|.||||  . |.|. ..||   | .                 .    .
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

IATLTEMPLPP-----NISPECADFLS----CCFKIDPHERHSCAELLNHPWL
   .   . |.     ..|||..||..    ...| .| .| .  ..|||||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase GL50803_16834.AA TyrKc 13-267 26 1.2e-42 148.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-267
Range on HMM: 1-280/280
Sequence Identity: 26% (78 aa)

YTLHCLIGKGAFAKVWKAADEVTGGFVALKQLEPKGKKKAVDQGFIKEVMSEINLLSKL--NHSNIVKYRGCFLEQ-------NYLYIILELVDFGSLQT
 ||   .| ||| .|.|.        || | | .           ... |.|.....||  .| |||.  |. ..|         |.|..|... |.|. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

LIKQYDD-LGENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLSQRLQDV------DPTVVE----GSP-----YWLAPEVINEE
 .. . . |       . .||  |  |||....|| |. | |.| .. . .| .|||||  . |       . . .     |.       |.|||.||. 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

GVSTKSDVWSLGATMIELLTK-KPPFHN-----LTGFAAMYNIATLTEMPLPPN--------ISPECADFLSCCFKIDPHERHSCAELLNHPWL
  .||||||| | .| |..|  ..|  .     .. . .. .. .   || |||         ..|  .  ..| . ||..| . .|.  |  .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_16834.AA Pkinase_Tyr 13-207 29 5.9e-39 132.55 Pfam 1-209 (270) Show / Hide 
Range on Protein: 13-207
Range on HMM: 1-209/270
Sequence Identity: 29% (63 aa)

YTLHCLIGKGAFAKVWKAADE----VTGGFVALKQLEPKGKKKAVDQGFIKEVMSEINLLSKL-NHSNIVKYRGCFL-EQNY--LYIILELVDFGSLQTL
 |.   .|.||| .|.|.        |.  || | | ..  ...    .... |.|......| .| |||.. |. . ..    .||..|..  |.| . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQN---CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

IKQY----DDLGENVVACYIYQILLGLKYLHEQGIIHKDIKAANILMTSSGLCKLTDFGLSQRL--QDVDPTVVEG---SPY-WLAPEVINEEGVSTKSD
 ..     . |      .. .||  |. ||.....|| |. | |.| |... .| .||||.  .   |   ... |    |  |.|||.||.   .||||
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSD

VWSLGATMIELLT
||| | .| |..|
VWSFGVLMWEIFT