GL50803_4959

Species: G.lamblia
Alias: GL50803_4959, GK233
External Links: GiardiaDB ,
Annotation:

Classification

Group: Other
Family: Nek
Subfamily: Nek-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
GL50803_4959.AA Protein None 1044 None Fasta, JSON
GL50803_4959.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of GL50803_4959.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_4959.AA NEK2 11-275 28 8.6e-53 176.04 In-house 2-319 (319) Show / Hide
Range on Protein: 11-275
Range on HMM: 2-319/319
Sequence Identity: 28% (91 aa)

ESLEMCGRGLFGKINRVRIQETEEVYACMEIDYSIISTEERIRLKREIEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFTLGDLADVIRFYRKEHTQI
| |.  |.| ||..  ||  .. .. .  ||.|      |.  |  |. ||  | |  .|||   . | ...  |. ||.   |||. .|  .|||.. .
EVLYTIGNGSFGRCRKVRRKSDGKILVWKEICYGHMQEKECQMLVSECNILRQLKHPNIVRYYDWIIDRQNSTLYIVMEYCEGGDLSQMIKKCRKERQYM

EEDRIWRIFAQLLIAMEYCHS---------------VRKPN-AIHVGSIVHRNIIPSNIFVGEGDL----------------------------------
||  ||||..||..|   ||                 |...  .    | || | | |||  . .                                   
EEEFIWRIMFQLCTALQECHNGVELPTLTTIYDRMKPRIDGKHT----ILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMD

-----IKLGYFSLHQVLGSNSLIRDAES----PFYTAPEILQQLPYTEKADVWSLGCVVYELCTLRRPFIELEGESLVDVIMHNSYEPIMNEYSQELRDT
     .||| | |  .|   ..   | .    |.|  || .. ..| || |.||.||..||.|.|. ||       |   |    ...|   ||..| . 
YSQVVVKLGDFGLARMLNHDTSF--AHTFVGTPYYMSPEQMHGQKYNEKSDIWSVGCLIYEMCALHPPFQATNQAQLQEKIKQGHFRRIPYQYSRHLNEI

VSLMLSVDPNARPSAADLLGLPKF
...|. ||.  |||   .|. |  
IHFMINVDHYHRPSIEEILQHPQI

S_TKc GL50803_4959.AA S_TKc 10-275 27 4e-42 147.17 SMART 1-231 (231) Show / Hide
Range on Protein: 10-275
Range on HMM: 1-231/231
Sequence Identity: 27% (77 aa)

AESLEMCGRGLFGKINRVRIQETEEVYACMEIDYSIISTEERIRLKREIEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFTL--GDLADVIRFYRKEH
 | |.  |.| |||  ..|  .| ...|. .|.         ....|||.|| .  |...|..... .|   .  |. ||.     ||| |.|. .... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHG

TQ--IEEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGEGDLIKLGYFSLHQVLGSNSLIRDAESPFYTAPEILQQLPYTE-KADVW
..  . | .......|.. |.||||| .         |.|| . |.||.. |   ||.. | |  .|          .|.| |||.|   .|.  |.|.|
LRFPFPE-HARFYMYQICCALEYCHSHG---------IIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWW

SLGCVVYELCTLRRPFIELEGESLVDVIMHNSYEPIMNEYSQELRDTVSLMLSVDPNARPSAADLLG-------LPKF
|.||..||... . ||   . . . ..|.           |.|..| .. .| .||. ||.| ..|         | |
SCGCILYEMLCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase GL50803_4959.AA NEK 184-275 43 2.9e-36 125.35 In-house 188-286 (286) Show / Hide
Range on Protein: 184-275
Range on HMM: 188-286/286
Sequence Identity: 43% (43 aa)

PFYTAPEILQQLPYTEKADVWSLGCVVYELCTL--RRPF---IELEGESLVDVIMHN-SYEPIMNE--YSQELRDTVSLMLSVDPNARPSAADLLGLPKF
| | .||..|. ||..|.|.||||||.||.|||  ..||   . .  .||.  || .  |.||     |||.|.. .|.|| .||  |||. ..| .|  
PYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWD-MNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPFI





Kinase GL50803_4959.AA NEK10 63-264 31 7e-34 108.9 In-house 69-265 (279) Show / Hide
Range on Protein: 63-264
Range on HMM: 69-265/279
Sequence Identity: 31% (65 aa)

HLVHKHVVRYLESVYD-HEAKMSYLLMEHFTLGDLADVIRFYRKEHTQIEEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGEGDLI
.. |  .|||          .| |  ||      | . .   .  |   ||.|||..| |.. |. | |  ..        ||||   | ||  |. | .
QMRHPNIVRYYRTFVEPQNHRM-YIVMELIEGCPLYEHFNSMKEKHHHFEEERIWHMFIQMCLALRYLHKEKQ--------IVHRDLTPNNIMMGDKDRV

KLGYFSLHQVLG--SNSLIRDAESPFYTAPEILQQLPYTEKADVWSLGCVVYELCTLRRPFIELEGESLVDVIMHNSYEPIMN-EYSQELRDTVSLMLSV
    | | .  .  .  .   .    |  |||.| .|| ||||||. ||..|..|||. ||      .|   |    |.|.    .|...|.|..  |  
TITDFGLAKQKQPDPSKMTSVVGTILYSCPEIVQSEPYGEKADVWAFGCCLYQMCTLQPPFYSTNMLTLAMKIVEHFYDPVNEGMWSDDVRFTITRCLTP

DPNARP
||.|||
DPEARP

Kinase GL50803_4959.AA STE 10-275 20 1e-33 116.46 In-house 1-359 (359) Show / Hide
Range on Protein: 10-275
Range on HMM: 1-359/359
Sequence Identity: 20% (76 aa)

AESLEMCGRGLFGKINRVRIQ------ETEEV---------YACMEID---------------YSIISTEERIRLKREIEILPHLV--HKHVVRYLESVY
 | .|. |.| ||.  . .        .| ||         .|  ...               .... .||. ....||.|. ..   |...|.|. . .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

D----HEA-KMSYLLMEHFTLGDLADVIRFYR---KEHT-------QIEEDRIWRIFAQLLIA-MEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGEGDLI
.    |..    .. ||.   | | |.|. .    |...        ..|. | .|  |.| . ..| || .         |.|| | |.||..     .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---------IIHRDIKPANILL-----V

KLGYFSLHQVLGSN------------------SLIRDAESPFYTAPEILQQ------LPYTEKADVWSLGCVVYELCTLRRPFIE-LEGESLVDVIMH--
||  | .   | ..                      .. .| . |||..||       .|..|.|.|||||.. |..| . |. .    . .   ..   
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH

------------NSYEPIMN-------------------EYSQELRDTVSLMLSVDPNARPSAADLLG--LPKF
            .   |. .                   ..|.|..| ... |  ||| ||.| .||    | .
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI

Kinase GL50803_4959.AA Ciliate-E2 10-275 20 3.3e-32 107.87 In-house 1-365 (365) Show / Hide
Range on Protein: 10-275
Range on HMM: 1-365/365
Sequence Identity: 20% (81 aa)

AESLEMCGRGLFG-----KINRVRIQE------------------TEEVYACMEIDYS-IISTEERIRLKREIE----------ILPHLVHKHVVRYLES
 . ....|.| ||     |  .|. |.                  .   ||   .  . |....  |.. |||.          || .| |...... |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VYDHEAKMSYLLMEHFTLGDLADVIRFYRKEHTQI-------EEDRIWRIFAQLL---------------IAMEYCHSVRKPNAIHVGSIVHRNIIPSNI
 ..   .  || || .  ||| | |.  .| ....        |  | .|..|.|                |.||.||          .|.||.| |.||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKN--------NIIHRDIKPENI

FVGEGDLIKLGYFSL-----------HQVLGSNSLIRDAE------------------------SPFYTAPEILQQLP---------YTEKADVWSLGCV
..     ||.  | |            . .  . .. .                          .| | |||||.  .         |..|.|.||||..
LF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

VYELCTLRRPFIELEGESLVDVIMHNSYEPIMN-------------------------EYSQELRDTVSL----MLSVDPNARPS-AADLLGLPKF
 ||... ..||                .. |..                         . |||  |  .     || .||. |.. . ..|  | |
LYEMLFGKPPF----------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase GL50803_4959.AA NEK6 56-266 31 1.3e-31 101.09 In-house 48-252 (252) Show / Hide
Range on Protein: 56-266
Range on HMM: 48-252/252
Sequence Identity: 31% (67 aa)

REIEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFTLGDLADVIRFYRKEHTQIEEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFV
.||..|  | |..|..|..|  .       . .|    ||.. .|....|.   | |  ||. | ||  |.|  || |         ..|| | | |.|.
KEIDLLKQLNHPNVIKYYASFIENNELN--IVLELADAGDMSRMIKHFKKQKRLIPERTIWKYFVQLCSALEHMHSKR---------VMHRDIKPANVFI

GEGDLIKLGYFSLHQVLGSNSLIRDA--ESPFYTAPEILQQLPYTEKADVWSLGCVVYELCTLRRPFI--ELEGESLVDVIMHNSYEPIMNE-YSQELRD
     .|||   |     |.     .    |.| .|| ..   |  |.|.|||||..||.  |  ||    .   ||   | .  | |.  . ||..||.
TANGIVKLGDLGLGRFFSSKTTAAHSLVGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPADHYSEQLRQ

TVSLMLSVDPNARPSA
 |....  ||. ||  
LVCMCIHPDPEWRPDI

Kinase GL50803_4959.AA Ciliate-E2-Unclassified 11-275 19 1.2e-30 103.6 In-house 2-352 (352) Show / Hide
Range on Protein: 11-275
Range on HMM: 2-352/352
Sequence Identity: 19% (70 aa)

ESLEMCGRGLFGKINRVRIQETEEVY-------ACMEIDYSIISTEERIRLKREIEILPH----------------LVHKHVVRYLESVYDHEAKMSYLL
. .. .|.| |||. ...  ..   |         ....  .| ... . .  ..|.  .                | |.| ... .  ..   .  |. 
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MEHFTLGDLADVIRFYRK------------EHTQIEEDRIWR------IFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGEGD---LIKLGYF
|| .  ||| . |. . |            ....| ...  .      .|||.| . ||.|        | . |.||.| |.||.. ..     ||.  |
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLH--------HKNNIIHRDIKPENILFDNNGKNYYIKIIDF

SLHQ-----------------VLGSNSLIRDAESPFYT----APEILQQLPYT----EKADVWSLGCVVYELCTLRRPFI--------------------
..                   .. .. .   . .| |     |||.||.  |     .|.|.||||.. ||... ..||                     
GISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYR

-ELEGESLVDVIMHNSYEP--IMNEYSQELRDTVS----LMLSVDPNARPSAADLLGLPKF
 .|. . .   |  .....  |    |.|  | ..     || ..|| |... ..|  | |
KQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase GL50803_4959.AA NEK-Unclassified 58-275 29 1.2e-30 98.41 In-house 44-258 (258) Show / Hide
Range on Protein: 58-275
Range on HMM: 44-258/258
Sequence Identity: 29% (69 aa)

IEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFTLGDLADVIRFYRKEHTQIEEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGE
| ||  | | |.| | .| ..  ||. |   .    |.|   |.  ||    ..| || . . |.  |. | |. ||        |.||   |.|||  .
IIILSQLRHPHIVTYHDSFFE-NAKLFY-TQDYCDGGNLDRRIQKHRKKNEPFDEGRIMQWCIQMIMAVQYIHQ-RK--------IIHRDLKPQNIFLTD

GDLIKLGYFSLHQVLGSNSLIRDAE----SPFYTAPEILQQLPYTEKADVWSLGCVVYELCTLRRPFIELEGESLVDVIMH-----N----SYEPIMNEY
 |.. .| |    ..  .     |     .. . .||..|. || .. |||||||..||.||   ||  .   .. .| |      |      ||.   |
DDTVSMGDFGISRIM--DHTRDKARTCVGTMCWMSPEVCQDQPYNNRSDVWSLGCIIYEMCTCE-PF--FDTHNMGEVYMKIKQDDNRLEEALEPVSKTY

SQELRDTVSLMLSVDPNARPSAADLLGLPKF
|  | . .  ||  ... |||| ... ..  
STDLQQVIRFMLRRNFQQRPSATEIVEQDYI

Kinase GL50803_4959.AA NEK1 184-275 46 1.6e-30 103.14 In-house 185-276 (276) Show / Hide
Range on Protein: 184-275
Range on HMM: 185-276/276
Sequence Identity: 46% (43 aa)

PFYTAPEILQQLPYTEKADVWSLGCVVYELCTLRRPFIELEGESLVDVIMHNSYEPIMNEYSQELRDTVSLMLSVDPNARPSAADLLGLPKF
| |  ||| | .||. | |.|||||| |||||| .||       ||  |   .| || . ||.||.  || |....|  |||. ..|  |  
PYYLSPEICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKICQGTYPPIPPHYSYELQSLVSQMFKRNPRHRPSVNQILERPFI

Kinase GL50803_4959.AA NEK4 11-275 28 3.7e-27 94.65 In-house 2-257 (257) Show / Hide
Range on Protein: 11-275
Range on HMM: 2-257/257
Sequence Identity: 28% (77 aa)

ESLEMCGRGLFGKINRVRIQETEEVYACMEIDYSIISTEERIRLKREIEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFTLGDLADVIRFYRKEHTQI
. .   |.| .| .  || .     |    ..    | .||    .|...|  | |  .| | ||    . .. |  |     |||    .  ..    .
CHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDL--YRKLKQQKNQFL

EEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGEGDLIKLGYFSLHQVLG-SNSLIRD-AESPFYTAPEILQQLPYTEKADVWSLGC
||  .   | |  .|. | |  .         |.||     |||     .||.| | .  ||  .  . .     |.|  ||.    ||  | |.|||||
EEYQVVEWFVQIAMALQYMHEKH---------ILHRDLKTQNIFLTKKNIIKIGDFGISRVLNNHCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSLGC

VVYELCTLRRPFIELEGESLVDVIMHNSYEPIMNEYSQELRDTVSLMLSVDPNARPSAADLLGLPKF
 |||. ||.  |   .  ||.  |.     |.  .|||.| . |  ||.  |. |||  |..  |  
CVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI

Kinase GL50803_4959.AA Pkinase 183-275 26 2.2e-19 69.64 Pfam 174-293 (293) Show / Hide
Range on Protein: 183-275
Range on HMM: 174-293/293
Sequence Identity: 26% (32 aa)

SPFYTAPEILQ-QLPYTEKADVWSLGCVVYELCTLRRPFIEL------EGESLVDVIMH---NSYEPIMNEYS-----------------QELRDTVSLM
.|.| |||... . .|. |.|.||.||..||... | || .       .   ... ||.    . .|  .. |                 .|..| .. .
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

LSVDPNARPSAADLLGLPKF
| .||. ||.|...|  | |
LCKDPKKRPTAEQILQHPWF

Kinase GL50803_4959.AA NEK 11-164 27 1.9e-17 58.35 In-house 2-165 (286) Show / Hide
Range on Protein: 11-164
Range on HMM: 2-165/286
Sequence Identity: 27% (47 aa)

ESLEMCGRGLFGKINRVRIQETEEV-----YACMEIDYSIISTEERIRLK-REIEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFT-LGDLADV---I
| ... |.| |||  .|| .... .     |.  .|...  | .|.  .   |. || .| | ..|.| .| ....  . .  ||.    |||..    |
EIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKSI

RFYRKEHTQIEEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGE-GD---LIKLG
  ...... .||. ||..|.|...|. |.|. || .    . |.|| | |.|||    .    ..|.|
KKQKQKGKYFEEEQIWDWFIQMCLALKYMHD-RK-GP--QRKILHRDIKPQNIFLTKNNNDYHNVKIG

Kinase GL50803_4959.AA Pkinase 17-164 25 6.9e-17 60.79 Pfam 8-154 (293) Show / Hide
Range on Protein: 17-164
Range on HMM: 8-154/293
Sequence Identity: 25% (41 aa)

GRGLFGKINRVRIQETEEVYACMEIDYSIISTEERIRLKR--EIEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFTLG----DLADVIRFYRKEHTQI
|.| ||.  . . . |....|. .|... .. ...... |  ||.|. .| |...||......|   .  |. ||.   |    ||.|.|.   ..|. .
GSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIST--WRHGCF

--EEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVG-EGDL---IKLG
  .|. . ... |.| ..|||||          .|.|| . |.||..  .|..   .|..
YFSEWECKFYMYQILRGLEYCHSM---------GIIHRDLKPENILIDNNGHIDACVKIC

Kinase GL50803_4959.AA TyrKc 10-275 19 9.8e-15 15.57 SMART 1-280 (280) Show / Hide
Range on Protein: 10-275
Range on HMM: 1-280/280
Sequence Identity: 19% (59 aa)

AESLEMCGRGLFGKINRVRIQETEEVYACMEIDYSIISTEERIRLKREIEILPHL--VHKHVVRYLESVYDH-----EAKMSYLLMEHFTLGDLADVIRF
 . ... |.| ||.. . .    ..|   |  ...      |  . ||..|. .|   |...|| .  . ..     ...  ...||.  .||| | .| 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YRKEHTQIEEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVGEGDLIKLGYFSLHQVLGSN-------SLIR-----DAE--SP-FYT
.|..   .  .    .  |    ||| ||           ..|| .   |. |||.  .| . | |   ...        . .|     ..    |   .
HRPK---LCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APEILQQLPYTEKADVWSLGCVVYELCTL-RRPFIE-----LEGESLVDVIMHNSYEPIMNE--------YSQELRDTVSLMLSVDPNARPSAADLLGLP
||| ..   .|.| |||| | . .|..|.   |  .     .. . ..  ...  . |.. .         ..|. .  .     ||. ||. ...    
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HE

KF
.|
CF

Kinase GL50803_4959.AA NEK1 11-164 26 4e-07 20.93 In-house 2-163 (276) Show / Hide
Range on Protein: 11-164
Range on HMM: 2-163/276
Sequence Identity: 26% (45 aa)

ESLEMCGRGLFGKINRVRIQETEEVYACMEIDYSIISTEERIRLKREIEILPHLVHKHVVRYLESVYDHEAKMSYLLMEHFTLGDLADVIRFYRKEHTQI
. . . | | |||   |.  |   .|.  ||  .  . .|| . ..|  ||  . |  .|.| ||       . |  ||    |||.  |   .     .
HYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQKRKGKLF

EEDRIWRIFAQLLIAMEYCHSVRKPNAIHVGSIVHRNIIPSNIFVG--EGD---------------LIKLG
 || |   | |. .|. . |. .         | || | ..|||    ...               |.|||
SEDQIMHWFCQICLALNHIHDRK---------ILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLG

Kinase GL50803_4959.AA Pkinase_Tyr 187-216 40 2e-06 22.07 Pfam 181-210 (270) Show / Hide
Range on Protein: 187-216
Range on HMM: 181-210/270
Sequence Identity: 40% (12 aa)

TAPEILQQLPYTEKADVWSLGCVVYELCTL
.||| ..   .|.| |||| | . .|..|.
MAPECINYGKFTTKSDVWSFGVLMWEIFTY

Ank GL50803_4959.AA Ank 712-724 46 1.612193 6.13 Pfam 1-13 (33) Show / Hide
Range on Protein: 712-724
Range on HMM: 1-13/33
Sequence Identity: 46% (6 aa)

PGDTPLMLAVTKN
 |.|||.||. ..
DGFTPLHLACRCG

Ank GL50803_4959.AA Ank 740-761 27 0.002335 16.37 Pfam 1-22 (33) Show / Hide
Range on Protein: 740-761
Range on HMM: 1-22/33
Sequence Identity: 27% (6 aa)

YGRTALMRAAYHNNVPAVRLLV
.|.|.|. |......  |..|.
DGFTPLHLACRCGHTEVVKMLL

Ank GL50803_4959.AA Ank 771-791 33 0.001542 17.02 Pfam 1-21 (33) Show / Hide
Range on Protein: 771-791
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

DGNTALMFAVERENHACVSIL
||.|.|. |... .. .|. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_4959.AA Ank 802-824 26 0.004282 15.42 Pfam 1-23 (33) Show / Hide
Range on Protein: 802-824
Range on HMM: 1-23/33
Sequence Identity: 26% (6 aa)

TGLSALMRAACNGSPQIVELLCS
 | ..|. |...|....|..| .
DGFTPLHLACRCGHTEVVKMLLQ

Ank GL50803_4959.AA Ank 833-856 33 0.012596 13.73 Pfam 1-24 (33) Show / Hide
Range on Protein: 833-856
Range on HMM: 1-24/33
Sequence Identity: 33% (8 aa)

EGLTALMLAALAEDAKSVSILLKR
.| |.|.||..  ... |. ||..
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_4959.AA Ank 864-884 33 0.393267 8.34 Pfam 1-21 (33) Show / Hide
Range on Protein: 864-884
Range on HMM: 1-21/33
Sequence Identity: 33% (7 aa)

DGTSALLMATSTGNMNVIRQL
|| ..| .| . |...|.. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_4959.AA Ank 895-915 42 0.000289 19.64 Pfam 1-21 (33) Show / Hide
Range on Protein: 895-915
Range on HMM: 1-21/33
Sequence Identity: 42% (9 aa)

SGRTPLMVAAEMGHLEAARFL
 |.|||..|...||.| ...|
DGFTPLHLACRCGHTEVVKML

Ank GL50803_4959.AA Ank 926-946 47 2.7e-05 23.38 Pfam 1-21 (33) Show / Hide
Range on Protein: 926-946
Range on HMM: 1-21/33
Sequence Identity: 47% (10 aa)

DGETALMIASFHGHAEVARIL
||.|.|..|...||.||.. |
DGFTPLHLACRCGHTEVVKML

Ank GL50803_4959.AA Ank 957-980 33 0.000814 18.02 Pfam 1-24 (33) Show / Hide
Range on Protein: 957-980
Range on HMM: 1-24/33
Sequence Identity: 33% (8 aa)

DGWTAMMYAASFGHCSIIETLLRR
||.|. ..|.. || .... || .
DGFTPLHLACRCGHTEVVKMLLQH

Ank GL50803_4959.AA Ank 988-1018 27 0.000902 17.86 Pfam 1-33 (33) Show / Hide
Range on Protein: 988-1018
Range on HMM: 1-33/33
Sequence Identity: 27% (9 aa)

CGQTALMNAVANNQFEAVRLLVS--AEGTIKDA
.|.|.|. |. ... | |..|..  |.  ..| 
DGFTPLHLACRCGHTEVVKMLLQHGADVNAQDD

Ank GL50803_4959.AA Ank 1019-1039 23 1.409923 6.34 Pfam 1-21 (33) Show / Hide
Range on Protein: 1019-1039
Range on HMM: 1-21/33
Sequence Identity: 23% (5 aa)

SGKTALDQAIELNNADMIAFL
 | |.|  |.. ...... .|
DGFTPLHLACRCGHTEVVKML