Gene GL50803_5811 (G.lamblia)
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_5811.AA | Protein | None | 416 | None | Fasta, JSON |
| GL50803_5811.kin_dom | Protein Kinase Domain | None | 263 | None | Fasta, JSON |
Protein domains of GL50803_5811.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | GL50803_5811.AA | RIO2 | 81-296 | 40 | 5.6e-72 | 244.74 | In-house | 1-211 (260) | Show / Hide |
Range on Protein: 81-296 Range on HMM: 1-211/260 Sequence Identity: 40% (89 aa) YALTYMGYDYLSLNVMKRRGVISAIGSRIGVGKEADVYMAMRPNGQYVVLKLHKLGRTSFKTAKTKRDYMGPRKSASWMYLSRLAAVREFGFMVALKERS | || ||||| | . | |. .| .||||| |.| ||. ...|.| ||||||.. | .|||. | ..||||||||.|. |. || .| .| YRLTNAGYDYLALKTLSSRQVVYSVGNQMGVGKESDIYKCSNENGNQFIMKFHRLGRTSFHNIKNNRDYHKHRHQYSWMYLSRLSAMKEYQFMDMLYKRN FPVPDPISINRHCVCMSYVEGIPMHAIKDIDIEAANLLAKDIHTQMVRMLRYGIVHGDCNEFNAIVQTSDP--ENCTPETTRVVIIDFPQVIQSIAPEAE |||| || ||| | |. ..| || .|. .| . . . ||. | .|.| |||| .. .| | ...||||| . ..|. FPVPKPIDYNRHIVVMELINGYPMCQIHHHDNPPY--VYDQCMCFIVRLANHGLIHCDFNEFNLMIDDNDHDENDCG-----FIMIDFPQMVSTQHQNAQ EQFNRDVMSVEGFFNRRF | ||| . || .|| WYFDRDVDCIHRFFMKRF |
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| Kinase | GL50803_5811.AA | RIO | 81-296 | 31 | 8.2e-55 | 186.38 | In-house | 1-234 (276) | Show / Hide |
Range on Protein: 81-296
Range on HMM: 1-234/276
Sequence Identity: 31% (75 aa)
YALTYMGYDYLSLNVMKRRGVISAIGSRIGVGKEADVYMAMRPNGQ-----------YVVLKLHKLGRTSFKTAKTKRD---YMGPRKS-ASWMYLSRLA
| .| .|... . | ||.. .| ||||||.|.| . ||. ...|.|..||||||. | .|| | | . ..|.|..||.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLW
AVREFGFMVALKERSFPVPDPISINRHCVCMSYVEG-------IPMHAIKDIDIEAANLLAKDIHTQMVRMLRYG-IVHGDCNEFNAIVQTSDP--ENCT
| |. .| .| ...||.| || .|| . |. .. || | . .|. . . |.|. . ||.| |||| .. .. |
AEKEMRNMKRLYQSGFPCPEPIDYKRHVLVMEFINHDQMPAPKYPMCQI--HEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCG
PETTRVVIIDFPQVIQSIAPEAEEQFNRDVMSVEGFFNRRF
...||||| . | |.. | ||. | || .||
-----FYMIDFPQMVEHDHPHALWYFRRDCKCVNMFFMKRF
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| Rio2_N | GL50803_5811.AA | Rio2_N | 18-99 | 47 | 1.2e-43 | 149.69 | Pfam | 1-84 (84) | Show / Hide |
Range on Protein: 18-99 Range on HMM: 1-84/84 Sequence Identity: 47% (40 aa) VDSLPPSYYRVLTAVEMGMKNHDYVPLNLVISLSGIR-HGSIPHIVQELLKIKLISH-IGAPIDGYALTYMGYDYLSLNVMKRR . .| . ..||||||||||.||..|| .|. ..|..| ||.. .....|.| ||||| ... |||.|||.||||| |. . .| MRYLSKEDFRVLTAVEMGMRNHEWVPTELIHQISRLRSHGGCHYRLSRLCKHKLISHVQNKKYDGYRLTYGGYDYLALHTFVKR |
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| Kinase | GL50803_5811.AA | RIO1 | 116-306 | 28 | 2.4e-43 | 135.67 | Pfam | 1-200 (200) | Show / Hide |
Range on Protein: 116-306 Range on HMM: 1-200/200 Sequence Identity: 28% (60 aa) DVYMAMR-PNGQ-YVVLKLHKLGRTSFKTAKTKRDYMGP----RKSASWMYLSRLAAVREFGFMVALKERSFPVPDPISINRHCVCMSYVE---GIPMHA .|| |. ..|. ....|....|.|.|| | .||| . .| |..|..| .|| ......|. .|.| || |||.. |... |.|. NVYHAYSMEDGKDECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAGVPCPKPIDWNRHVLVMEFIGDKDGWPAPR IKDID-------IEAANLLAKDIHTQMVRML-RYGIVHGDCNEFNAIVQTSDPENCTPETTRVVIIDFPQVIQSIAPEAEEQFNRDVMSVEGFFNRRFGA .|| . ||. .... |. .| ||. . |.|||| .|.| .| . ..|||.|| | |.| . ||. . || |.... LKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDG---------KPWIIDWPQAVEHDHPHALEFLERDCRNIINFFRRKGVD D-IVLPRYN . .. .|. ERVMDFREI |
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| RIO | GL50803_5811.AA | RIO | 75-314 | 26 | 6.6e-36 | 126.53 | SMART | 2-253 (253) | Show / Hide |
Range on Protein: 75-314 Range on HMM: 2-253/253 Sequence Identity: 26% (69 aa) GAPIDGYALTYMGYDYLSLNVMKRRGVISAIG--SRIGVGKEADVYMA----MRPNGQYVVLKLHKLGRTSFKTAKTKRDYMG--PRKS-----ASWMYL . ..|.... ..... |. | .||.|..|. |..||||.|| | ..|| ... | .....|.| |... | .| . ..|... KEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGGDFDKNGNECAVKIYRTSTTEF---KRMWRYIQGDFRFKHGYHHINWRKM SRLAAVREFGFMVALKERSFPVPDPISINRHCVCMSYVEG--IPMHAIKDIDIEAA------NLLAKDIHTQMVRMLRYG-IVHGDCNEFNAIVQ-TSDP .||.| .|| .. ..| .|.| || .|| . |..... .|. ||...| . ... ..| |..| . . .||.| .|.| .. | VRLWAEKEFRNLQRMYEAGVPCPKPIAWRRHVLVMEFIGDDGWPAPRLKDVEWEEWEMDFKWEYY-WQIMEYMRKMYHECHLVHADLSEYNMLYHDLEDE ENCTPETTRVVIIDFPQVIQSIAPEAEEQFNRDVMSVEGFFNRRFGADIVLPRYNEVMRQISE ..| |.|||..| . |...| . ||. . || || | | . |.| . | . NDCK-----VWIIDWSQSVECDHPMWLEFLERDIWNIINFF-RRKGVDCDDI-YREIFERITG |
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| Kinase | GL50803_5811.AA | Ciliate-C1 | 104-131 | 31 | 0.00092 | 5.03 | In-house | 2-30 (328) | Show / Hide |
Range on Protein: 104-131 Range on HMM: 2-30/328 Sequence Identity: 31% (9 aa) AIGSRIGVGKEADVYMAMRPNGQ-YVVLK |. || |. ..| . ||.| . .| KIMKTIGHGYTCKVFYCKMPNNQKVYAVK |
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