Gene GL50803_6700 (G.lamblia)

GL50803_6700

Species: G.lamblia
Alias: GL50803_6700, GK041
External Links: GiardiaDB ,
Annotation:

Classification

Group: CMGC
Family: RCK
Subfamily: MAK

Sequence

Name Sequence Type Origin Length Description Download
GL50803_6700.AA Protein None 397 None Fasta, JSON
GL50803_6700.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of GL50803_6700.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase GL50803_6700.AA RCK 4-296 41 2.3e-119 380.49 In-house 1-298 (298) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-298/298
Sequence Identity: 41% (127 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQKYKSWSECVTLKEVKSLIRMKEHPNIVKLMEVVRQKE--DLYFVFEYINSGNLFDFVVQQRSAGIK
|..|..|| | ||.| ||.  ..| .|||| ||||..|| ||  |.|.||| ... ||||.|| ||.|...   |||||||    ||. .   .   . |
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQKFYSWEECMNLREIKSLRKLNPHPNIIKLKEVIRDNDTYQLYFVFEYMDM-NLYQMMKDFKE-RRK

-ISELV--AKDLVRQILEGLEHIHRNNYMHRDLKCENILVSD-----DGTGTRCVKIADLGCAKSLLERPPHTVYVGTRWYRAVELFLKDSSYSAKNDIW
 ..| .   |  . ||| ||.|.|.....||||| |||....     .   .  .|||| | ...   .|| | ||.|||||| |. |..  |. . |||
YLPENQRSIKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIW

ACACILCEILLMKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPNVTEDCINLLSRMFEFDQNKRLSAQDCLRH
|  ||  |.  ..|||||.. || .. |.. .|.|. .||| || ||. ....||        .|  |.|| . |||.|.  |   | .|| .|| .|.|
AVGCIMYELYMLRPLFPGSSEIDQIFKICKVMGTPNKKDWPDGYKLASQMNFNFPQCK---GMPLKQLIPNCSQDCIELMEKMLQWDPQKRITAQQALQH

PWF
| |
PYF
Kinase GL50803_6700.AA MAK 4-296 34 5.4e-103 328.75 In-house 1-352 (352) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-352/352
Sequence Identity: 34% (124 aa)

YTVITELGSGNYGTVYKARE------------------------------NKKGTLVAIKHMKQKYKSWSECVTLKEVKSLIRMKEHPNIVKLMEVVR--
|..|. || | ||.| .|..                              .. | .|||| ||.|. || ||. | |||||  .. ||||||| ||.|  
YQMIKQLGDGTYGCVMLAKRQFPLSNILGKQHDIRGTLMDQPKNGHQNYIIDTGEKVAIKRMKKKFYSWEECMNLREVKSLKKLNAHPNIVKLKEVIRDS

QKEDLYFVFEYINSGNLFDFVVQQRSAGIKISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGT-----------------RCVKIADLG
  . |||||||.   ||.. .   .     ....  .  . ||| || ..|.... |||.| |||..    .|.                   .|||| |
ENDHLYFVFEYMKE-NLYQMMKDRDRRHFPEPVI--RNIMYQILQGLAFMHKHGFFHRDMKPENIMC----MGPTQYFEKEYMNQIGYQDNELIKIADFG

CAKSLLERPPHTVYVGTRWYRAVELFLKDSSYSAKNDIWACACILCEILLMKPLFPGANDIDMLNLITSTLGSPTRED----------------WPAGYA
 |  .  .|| | || |||||| |  |. ..||.  |.||  ||  |.  ..|||||.. || .  |.. ||.|...|                || || 
LAREIRSKPPYTDYVSTRWYRAPEVLLRSTYYSSPIDMWAVGCIMAELYTFRPLFPGSSEIDQIFKICQVLGTPKKDDDFVNTNHITAPPPGGFWPDGYQ

LAERIGYKFPRATQSRQEKLRYLFPNVTE-DCINLLSRMFEFDQNKRLSAQDCLRHPWF
||  ....||         |  | ||  . | | |.  | ..| |||  ||.|...|.|
LAHMMNFRFPQCVPPSIMPLKHLIPNCSQSDAIELMKDMLQWDPNKRPTAQQCCKYPYF
Kinase GL50803_6700.AA CMGC 4-296 20 8.7e-100 328.62 In-house 1-513 (513) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-513/513
Sequence Identity: 20% (108 aa)

YTVITELGSGNYGTVYKARE--------------NKKGTLVAIKHMKQKYKSWSECV-----------TLKEVKSLIRMK----------------EHPN
|..|  .|.| ||.|||.|               .. . .|||| .|..     ..            .| |.| | ...                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKLMEVVRQKE-----------------DLYFVFEYINSGNLFDFVVQQRS-----AGIKISELV------------AKDLV------RQILEGLE--H
|||| .... |.                 .||.||||.   .|...  ...       ... || .             | ..      .|||.||.  .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

IHRNN--YMHRDLKCENILVSDDGTG----------------TRCVKIADLGCAKSLLERP----------------------PHTVYVGTRWYRAVELF
.|...   .||||| ||||......                   ..||.| | |... ...                      |.| || |||||| |. 
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LKDSSYS---------AKNDIWACACILCEILLM--------KPLFPGAND-----------IDMLNLITSTLGSPT---------------REDWPA--
| .. |.          . |.|...||. |...         |||||| ..           ||.|..|  .||.||                |.||   
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

-----------------------GYALAERIGYKFPRATQSRQEKLRYLFPN--------------------------------VTEDCINLLSRMFEFD
                       .. .. ... .||.      ..|   .||                                 ....|.||..|...|
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

QNKRLSAQDCLRHPWF
 .||..|...|.||.|
PDKRITAEQALQHPYF
Kinase GL50803_6700.AA S_TKc 4-296 28 1.1e-89 305.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-231/231
Sequence Identity: 28% (88 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQKYKSWSECVTLKEVKSLIRMKEHPNIVKLMEVVRQKEDLYFVFEYINS--GNLFDFVVQQRSAG--
|... ..|.| .|.|||.|..| | .|||| .|        . ...|.. | .   ||||||| .| .  ..||.|.||..   |.|||. ..... |  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

IKISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRCVKIADLGCAKSLLERPPHTVYVGTRWYRAVELFLKDSSYSA-KNDIWACACI
 ...| .|. ...||...||..|... .||||| ||||...      ..||.| | |. |      | ..||.||.| |..    .|.  | |.|.| ||
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCI

LCEILLMKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPNVTEDCINLLSRMFEFDQNKRLSAQDCLR------
| | |  .|.||  ..  |...|                                            ..............| .||..| ..|.      
LYEMLCGYPPFP--QMQMMFKKIG-------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

-HPWF
 ||||
CHPWF
Kinase GL50803_6700.AA Pkinase 4-296 32 1.4e-89 308.68 Pfam 1-293 (293) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-293/293
Sequence Identity: 32% (100 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQKYKSWSECVTLK---EVKSLIRMKEHPNIVKLMEVVRQKEDLYFVFEYINSG----NLFDFVVQQR
|...  .|||..|.|||... . | .||.| .| . .......|.    |.. . |.  |||||.| .... | ..|.|.|| . |     |||..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

SAGIKI--SELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRCVKIADLGCAKS--LLERPPHTVYVGTRWYRAVELFLKDSSYSAKNDI
... ..  || ..|. ..|||.|||..|... .||||| ||||....|.   ||||.| |.||   .   .  |...||.||.| |. .... |. | |.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

WACACILCEILLMKPLFPGA----NDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPNVTEDCINLLSRMFEFDQNKRLSAQ
|.| ||| | |. .|.|||.    | .|.. .|  ..| |...|||  .    .   .. . .    . .. . .|..|.|. ........| .||..|.
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H----F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAE

DCLRHPWF
..| ||||
QILQHPWF
Kinase GL50803_6700.AA CDK 4-296 30 8.2e-83 264.76 In-house 1-284 (284) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-284/284
Sequence Identity: 30% (102 aa)

YTVITELGSGNYGTVYKARENKKG-----TLVAIKHMK------QKYKSWSECVTLKEVKSLIRMKEHPNIVKLMEVVRQK-----------EDLYFVFE
|  . ..| | ||.|||||  . |      .||.|  .      .. |    . .. |.. |  .  |||||||..|. .|             ||.|||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YINSG--NLFDFVVQQRSAGIKISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRC--VKIADLGCAKSLL-------ERPPHTVYVG
|.      . |                 | . .|.|.||...|.|. ||||||. |||....|. . |  .|||| | |.          .. . |  | 
YMDHDLKKYMD----------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVK-CGRLKIADFGLARAFGIPHQMSEPNRTYTHEVV

TRWYRAVELFLKDSSYS--AKNDIWACACILCEILL---MKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPNV
|.|||| || | .. ||     |.|.. ||. |...    |||||| ..|| | .|  ..|.|| ..||    | .                        
TLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY-----------------------

TEDCINLLSRMFEFDQNKRLSAQDCLRHPWF
     .||..|. .| .||.||...| ||.|
-----DLLNKMLCYDPKKRISAEQALQHPYF
Kinase GL50803_6700.AA CDC2 4-296 33 2.3e-67 205.93 In-house 1-301 (301) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-301/301
Sequence Identity: 33% (105 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQKYKSWSE---CVTLKEVKSLIRMKEHPNIVKLMEVVRQKEDLYFVFEYINSGNLFDFVVQQRSAGI
|. |  .| | || |||..... ...||.|  . .. .  .     ...|   |  .|.||||||| .|. |   || ||||..  .|  .  .. . . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDM-DLKKYMDMSIPKNK

KISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRCVKIADLGCAKSLLERPPHTVYV-G----TRWYRAVELFLKDSSYSAKNDIWAC
.... . |..  |||.|... |..  ||||||  |||....|.    .|||| | |.      |. .|  .    |.|||| |. | .. ||   |.|. 
HMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN----IKIADFGLARAFGI--PIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSI

ACILCEI---LLMKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYK--FPRATQSRQEKLRYLFPN---------VTEDCINLLSRMFEFDQ
 ||. |.      ||||.|   || |  |  .||.|. ..||  . | .   ||  |||    .. .|. ..||         .....| ||..|   | 
GCIFAEMFMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPD---YKNTFPRW---KPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDP

NKRLSAQDCLRHPWF
.||.||.. |.||.|
QKRISAKEALQHPYF
Kinase GL50803_6700.AA MOK 4-296 32 2.6e-66 206.67 In-house 1-283 (283) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-283/283
Sequence Identity: 32% (95 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQKYKSWSECVTLKEVKSLIRMKEHPNIVKLMEVV--RQKEDLYFVFEYINSGNLFDFVVQQRSAGIK
|  |  .| | .  | | .  . |   | | |||...|  .  .|.|.. . |.  ||||..| |||  |.  .|  . | .   |... .   |     
YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQAMRRLNPHPNILMLHEVVFDRKTGNLALICELMDM-NIYELIRGRR---HY

ISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRCVKIADLGCAKSLLERPPHTVYVGTRWYRAVELFLKDSSYSAKNDIWACACILCE
...   .  . |..  |.|.|||   ||| | ||||. .|      .|.|| |  .|   . |.| |. |||||| |  | |  |. . |.|.  |.  |
LPQKKIMHYMYQLCKSLDHMHRNGIFHRDVKPENILIKQD-----HLKLADFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGYYTYQMDMWSVGCVFYE

ILLMKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPNVTEDCINLLSRMFEFDQNKRLSAQDCLRHPWF
|. ..|||||.|..| .  |   .| |  .        .  . | ||    |  ||   | ||.|. |.... .|  .|   |..|.  ..||.|
IASLHPLFPGVNEVDQISKIHDVMGTPCQKILNKFKNQSRAMNYDFPFKKGSGIEK---LTPNLTKQCLEIMHKMCTYDPDERITAHQVIQHPYF
Kinase GL50803_6700.AA Ciliate-E2 4-296 20 5.4e-61 208.11 In-house 1-365 (365) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-365/365
Sequence Identity: 20% (84 aa)

YTVITELGSGNYGTVYKARENKKGTL------------------VAIKHMKQKYKSWSECVTLKEVKSLIRMKE----------------HPNIVKLMEV
| .|  .|.||.|.|||..  |.. .                  |.||    |... ..   .| .....| ..                ||||.|. |.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VR--QKEDLYFVFEYINSGNLFDFVVQQ---------RSAGIKISELVAKDLVRQILE---------------GLEHIHRNN-YMHRDLKCENILVSDDG
    ... .|.|.||.. |.|||.  ..           .  ...|  .|.. .|||.               .||..| .|  .|||.| ||||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

TGTRCVKIADLGCAKSLLERPP--------------------------------HTVYVGTRWYRAVELFLKDSS--------YSAKNDIWACACILCEI
     .||.|.| .| . .                                   .  ..||  | | | . . .         |. | |||.. .|| | 
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

LLMKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPN-----------------VTEDCINLLSR----MFEFDQ
|  || |                                          |  | |... .|.                 ....|..|...    |.. |.
LFGKPPF----------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDP

NKRLS-AQDCLRHPWF
.||.. ....| ||||
EKRITGWEQILNHPWF
Kinase GL50803_6700.AA CDKL 4-296 32 1.7e-56 191.69 In-house 1-286 (286) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-286/286
Sequence Identity: 32% (97 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQ-KYKSWSECVTLKEVKSLIRMKEHPNIVKLMEVVRQKEDLYFVFEYINSGNLFDFVVQQRSAGIKI
|  .  .| | ||.|.| |    |..||||  |  ..       .. |.| . ..  |.||| | || |.|  |. ||||.   .. . . ...  |  .
YEKLGKVGEGSYGVVMKCRNKETGQIVAIKKFKESEDDPMVKKIAMREIK-MLKQLKHENIVNLIEVFRRKRKLHLVFEYCDH-TVLH-ELEEYPNG--V

SELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVS-DDGTGTRCVKIADLGCAKSLLERPP--HTVYVGTRWYRAVELFLKDSSYSAKNDIWACACIL
 | | .  . |||..... | .|  ||| | ||||..  .|.    ||. | | |. .|. |    | || |||||| || ..| .|.   |||| .|..
DEHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQ----VKLCDFGFAR-MLAKPGEIYTDYVATRWYRAPELLVGDTQYGKPVDIWAIGCVM

CEILLMKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPNVT-EDCINLLSRMFEFDQNKRLSAQDCLRHPWF
 | .   ||.|| .||| | .|  .||  . .     .     .| |||     . | |.  .||.  .  ....  ... |  .|........|| |
AEMIDGQPLWPGQSDIDQLYHIQKCLGPLIPRHQEIFSKNPFFHGMKFPEIE--HMEPLEKRYPNKSNKKALDFMKKCLHMDPDERMTCEQLMHHPYF
Kinase GL50803_6700.AA CDK4 4-296 33 2.3e-56 191.85 In-house 1-290 (290) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-290/290
Sequence Identity: 33% (101 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQKYKSW---SECVTLKEVKSLIR---MKEHPNIVKLMEVVRQKEDLY------FVFEYINSGNLFDF
|  . |.|.| |||||.||  . |  || |  .   .         |. |. |..|    .|||||||||.|  . .          ||| .    | ..
YQCVAEIGEGAYGTVYRARDLHTGHFVALKQVRIPIGEEGGGMPMSTIREI-SVMRHLCQFEHPNIVKLMDVCHVMDTDRAEMKITMVFEHCDW-DLHTY

VVQQRSAGIKISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRCVKIADLGCAKSLLERPPHTVYVGTRWYRAVELFLKDSSYSAKND
  .    |  ...  .|.. .|.| |..  | .   ||||| .||||. ||.    ||.|| | |.        |  | | |||| |  |  |.|    |
LDKCPPPG--MPPCTIKHMMHQLLRGVDFLHSHRIIHRDLKPQNILVTSDGH----VKLADFGLARIYSFQMALTPVVVTLWYRAPEVLLQ-SYYNTPVD

IWACACILCEILLMKPLFPGANDIDMLNLITSTLGSPTREDWPAGYALAERIGYKFPRATQSRQEKLRYLFPNVTEDCINLLSRMFEFDQNKRLSAQDCL
.|. .||  |.   .|||.| .. | |  |    | |. .|||   .|.      ||   | .. ... . |   .  . || .|  ..  ||.||  ||
MWSVGCIFAEMYCRRPLFCGQSEKDQLHKIFDVMGLPPEDDWPRDVSLPWD---HFP---QRHPRPFKDFCPHMCKQGDDLLQKMLCYNHHKRMSAYQCL

RHPWF
 ||.|
QHPYF
Kinase GL50803_6700.AA CAMK 9-199 20 8.7e-53 168.04 In-house 1-324 (425) Show / Hide 
Range on Protein: 9-199
Range on HMM: 1-324/425
Sequence Identity: 20% (68 aa)

ELGSGNYGTVYKARENKKG------------TLVAIKHMKQKYKS-----------------------WSECVTLKEVKSLIR-MKE---------HPNI
.||.|..|.|..... . .            . |||| .. |  .                       | . ...|.|.. |. ||          ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKLMEVVRQ-------------------KEDLYFVF---EYINSG----NLFDFVVQQRSAG-----------IKISELVAKDLVRQILEGLEHIHRNNY
.|| ||                      ....|.|.   ||.  |     |||..|.... |            ...|  |. ..|||.......| .| 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDLKCENILVSDDGTGT-------------RCVKIADLGCAKSLLE------------------------RPPHTVYVGTRWYRA-VELFLK------
.|||||.||||..|.....               .||.| | |. . .                         .. . ..||  | |  |....      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------DSSYSAKNDIWACACIL
          |. | |.|.| .||
QNATDEEKPYYGPKCDMWSCGVIL
Kinase GL50803_6700.AA Pkinase_Tyr 4-154 30 8.1e-25 84.67 Pfam 1-156 (270) Show / Hide 
Range on Protein: 4-154
Range on HMM: 1-156/270
Sequence Identity: 30% (48 aa)

YTVITELGSGNYGTVYKAREN----KKGTLVAIKHMKQKYKSWS--ECVTLKEVKSLIRMKEHPNIVKLMEVVR-QKED--LYFVFEYINSGNLFDFVVQ
 | . .||.|..|.|||.. .    .... ||.| .|... .        ..|.| .  .  |||||.|. |.  |.|   .| |.||   |.| |.  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

QRSAGIKISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRCVKIADLG
.|. . ...     .  .|| .|.|. ...|. |||| . |.||..    ...|||.| |
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFG
Kinase GL50803_6700.AA TyrKc 4-296 20 1.3e-16 45.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 4-296
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

YTVITELGSGNYGTVYKARENKKGTLVAIKHMKQKYKSWSECVTLKEVKSLIRM-KEHPNIVKLMEVVRQK-------EDLYFVFEYINSGNLFDFVVQQ
 | . .||.|..|.|||.. .   . ||.| .|       .   ..| . . .  ..|||||.|  |..|.       | |. |.||   |.| |.    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

RSAGIKISELVAKDLVRQILEGLEHIHRNNYMHRDLKCENILVSDDGTGTRCVKIADLGCAKSLLER----PPHTVYV-----GTR------WYRAVELF
|     ..     .   || .| |..|..|. |||| . |.||....    .|||.| | .. . .       . .|.     |..      |. | | .
RPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECI

LKDSSYSAKNDIWACACILCEIL-LMKPLFPG-----ANDIDMLNLITSTLGSPTRED----WPAGYALAERIGYKFPRATQSRQEKLRYLFPNVTEDCI
 ... .. | |.|.    . ||. . ..  ||      ......... .    |  ..                                 |.  ...  
-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------FVCCPDEMY

NLLSRMFEFDQNKRLSAQDCLRHPWF
.. ..  ..| ..| . ...  |  |
QIMKQCWHEDPEDRPTFSEI--HECF
Kinase GL50803_6700.AA CAMK 264-296 36 2.7e-14 41.75 In-house 393-425 (425) Show / Hide 
Range on Protein: 264-296
Range on HMM: 393-425/425
Sequence Identity: 36% (12 aa)

NVTEDCINLLSRMFEFDQNKRLSAQDCLRHPWF
.|...|..|...| . | .||.....||.|||.
FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM