Gene GL50803_90575 (G.lamblia)
GL50803_90575
Group:
Other
Family:
Other-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| GL50803_90575.AA | Protein | None | 847 | None | Fasta, JSON |
| GL50803_90575.kin_dom | Protein Kinase Domain | None | 222 | None | Fasta, JSON |
Protein domains of GL50803_90575.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | GL50803_90575.AA | FGFR | 455-489 | 45 | 6.9e-08 | 22.92 | In-house | 1-37 (293) | Show / Hide |
Range on Protein: 455-489 Range on HMM: 1-37/293 Sequence Identity: 45% (17 aa) LTLTELLGAGAFGKVFAADAL--HSARPGHLVKVAVK ||| . || |.||.| | | .|| . ..|||| LTLGKMLGEGCFGQVWMAEAKGIDCDRPEKEITVAVK |
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| Kinase | GL50803_90575.AA | BUB | 554-618 | 25 | 3.2e-07 | 21.72 | In-house | 91-156 (311) | Show / Hide |
Range on Protein: 554-618 Range on HMM: 91-156/311 Sequence Identity: 25% (17 aa) VMEYI-PGVTLFELCKQCYDRVERGLTCLPENVILWISYLMIKTVKTFHEANIVHTDIKVDNWLIT .|||. . || ... .. . ..| ... ... | |.|. |.. |.| ||| || ... WMEYHIDYGTLLDVINHMKEKAQVNNKVMHEYWVMFFCCQMLKMVEHLHRCEIIHGDIKPDNFMLM |
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| Kinase | GL50803_90575.AA | UTK | 455-489 | 37 | 3.9e-07 | 20.45 | In-house | 1-35 (296) | Show / Hide |
Range on Protein: 455-489 Range on HMM: 1-35/296 Sequence Identity: 37% (13 aa) LTLTELLGAGAFGKVFAADALHSARPGHLVKVAVK . | ..||.|||| |. |.. . . .. ...|||| VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVK |
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| Pkinase_Tyr | GL50803_90575.AA | Pkinase_Tyr | 455-489 | 34 | 5.5e-07 | 24.29 | Pfam | 1-34 (270) | Show / Hide |
Range on Protein: 455-489 Range on HMM: 1-34/270 Sequence Identity: 34% (12 aa) LTLTELLGAGAFGKVFAADALHSARPGHLVKVAVK .|. . ||.||||.|. . . .. ..|||| ITFGKKLGEGAFGEVYKGTWKG-DPDNTKIPVAVK |
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| Kinase | GL50803_90575.AA | S_TKc | 455-808 | 12 | 8.8e-07 | -77.43 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 455-808
Range on HMM: 1-231/231
Sequence Identity: 12% (44 aa)
LTLTELLGAGAFGKVFAADALHSARPGHLVKVAVKFFTRKKDSISVEIGEHAVCAISTSFLREIYSLSALTLRLADSLSDCLYTRFIASIVNNQGLGAFV
.. ...| ||||||. . . .||.| ...||| |. ... .... . .|
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-------------------EHIRREIQILKK---------HHPNIVKLYDVFQD--DHLYMV
MEYIPG--VTLFELCKQCYDRVERGLTCLPENVILWISYLMIKTVKTFHEANIVHTDIKVDNWLITISTDPTLLSFLKGKEEKGKTNVDQRVAACPTVKH
|||..| .||.. |.. . | .|| .. . | ... .. |. .|.| |.| .| |..
MEYCDGDLGDLFDYIKKRGRHGLR--FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------------------------------
ETQSCSSKTEKHVTPKLEADFGFADESGFLVPVACDFGKAIDASLFTLNDVPVQFHYTSMSVVTPC----PIVEKHWLY-EPDYSGIASCIWYMIIGTSV
. |. .|||.| . . ..|| .. .. . . | . ... |. |
-------------HIKI-CDFGLARQL-------------------------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPP
KASDLSVHRVDGERTVEVSLPSKRYWRHVDLFTSLLSQLFSFSTDTCGSYSMQRQ-----RLSDFT
. ... .. . . . ....... . . . | .. .
FP--------QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | GL50803_90575.AA | Fer | 455-489 | 39 | 2e-06 | 17.87 | In-house | 1-38 (283) | Show / Hide |
Range on Protein: 455-489 Range on HMM: 1-38/283 Sequence Identity: 39% (15 aa) LTLTELLGAGAFGKVFAAD-ALHSARPGHLVK--VAVK ||.. || ||||.|. . .|. ... .|. |||| VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVK |
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| Kinase | GL50803_90575.AA | Ciliate-B3 | 585-617 | 42 | 2e-06 | 20.15 | In-house | 1-33 (69) | Show / Hide |
Range on Protein: 585-617 Range on HMM: 1-33/69 Sequence Identity: 42% (14 aa) VILWISYLMIKTVKTFHEANIVHTDIKVDNWLI . | ......| || || | |||||| |. FALKHFHQVVEKIKILHEKNICHCDIKVDNILV |
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| Kinase | GL50803_90575.AA | PDGFR | 455-489 | 45 | 7e-06 | 14.43 | In-house | 1-35 (358) | Show / Hide |
Range on Protein: 455-489 Range on HMM: 1-35/358 Sequence Identity: 45% (16 aa) LTLTELLGAGAFGKVFAADALHSARPGHLVKVAVK | . ||.|||||| | | . . ||||| LQFGKTLGSGAFGKVVEATAYGLSKSQAVMKVAVK |
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| Kinase | GL50803_90575.AA | Ciliate-C3 | 587-628 | 38 | 8e-06 | 17.24 | In-house | 99-140 (140) | Show / Hide |
Range on Protein: 587-628 Range on HMM: 99-140/140 Sequence Identity: 38% (16 aa) LWISYLMIKTVKTFHEANIVHTDIKVDNWLITISTDPTLLSF | || ... . || |||| |||. | || . .. | LQISKQILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF |
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| Kinase | GL50803_90575.AA | TK | 455-489 | 22 | 9e-06 | 14.55 | In-house | 1-58 (486) | Show / Hide |
Range on Protein: 455-489 Range on HMM: 1-58/486 Sequence Identity: 22% (13 aa) LTLTELLGAGAFG---KVFAA--------------------DALHSARPGHLVKVAVK .|| . ||.|.|| .|. . .. . | ..|||| ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVK |
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| Kinase | GL50803_90575.AA | Ciliate-A9 | 455-472 | 33 | 4.9e-05 | 6.98 | In-house | 1-18 (392) | Show / Hide |
Range on Protein: 455-472 Range on HMM: 1-18/392 Sequence Identity: 33% (6 aa) LTLTELLGAGAFGKVFAA . . . .| ||||.|. . FEPIKIIGEGAFGCVIQC |
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| Kinase | GL50803_90575.AA | STE | 455-472 | 44 | 0.002353 | 7.85 | In-house | 1-18 (359) | Show / Hide |
Range on Protein: 455-472 Range on HMM: 1-18/359 Sequence Identity: 44% (8 aa) LTLTELLGAGAFGKVFAA ... | .| ||||.|. | WEGIEKIGKGAFGTVYKA |
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| Kinase | GL50803_90575.AA | Pkinase | 553-614 | 22 | 0.006686 | 11.34 | Pfam | 77-138 (293) | Show / Hide |
Range on Protein: 553-614 Range on HMM: 77-138/293 Sequence Identity: 22% (15 aa) FVMEYIPGV----TLFELCKQCYDRVERGLTCLPENVILWISYLMIKTVKTFHEANIVHTDIKVDN .|||| .| ||.. . . ..... ..|... . | ... .. |. .|.| |.| .| MVMEYCEGGLYVMDLFDYIST---WRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPEN |
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| Kinase | GL50803_90575.AA | Pkinase | 455-502 | 18 | 0.00709 | 11.25 | Pfam | 1-43 (293) | Show / Hide |
Range on Protein: 455-502 Range on HMM: 1-43/293 Sequence Identity: 18% (9 aa) LTLTELLGAGAFGKVFAADALHSARPGHLVKVAVKFFTRKKDSISVEI ... . .|.|.||.|. . . . .|||| . ..... .... YHIGRKIGSGSFGCVYKCHHKGTGK-----IVAVKIIKKRHEKSWKDQ |
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| Kinase | GL50803_90575.AA | STE | 554-611 | 27 | 0.007259 | 6.1 | In-house | 115-179 (359) | Show / Hide |
Range on Protein: 554-611 Range on HMM: 115-179/359 Sequence Identity: 27% (18 aa) VMEYIPGVTLFELCKQCYDRVERGL------TCLPENVILWISYLMIKT-VKTFHEANIVHTDIK .|||..| .| .. |..| . .. ...||..| .| . .| . |. .|.| ||| CMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIK |
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