Gene Haspin (Fruit Fly)

Haspin

Species: Fruit Fly
Alias: Haspin, SFO005
External Links: Flybase Link ,
Annotation: Drosophila polytene location: Unmapped,

Classification

Group: Other
Family: Haspin

Sequence

Name Sequence Type Origin Length Description Download
Haspin.AA Protein Various 566 None Fasta, JSON
Haspin.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 267 Kinase domain by global Sugen HMM Fasta, JSON
Haspin.NA RNA None 1843 None Fasta, JSON

Protein domain

Protein domains of Haspin.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase Haspin.AA Haspin 250-511 35 2.5e-112 379.47 In-house 1-264 (264) Show / Hide 
Range on Protein: 250-511
Range on HMM: 1-264/264
Sequence Identity: 35% (95 aa)

NTKKIGEGAYGEVFRCSRNQEVLKDHISDIVLKIIPLEGSTV-----INGEKQKTFSQILPEIIITKKMCSLRT-SKTNSTNGFVSIQKVSLVKGRYPPH
| ||||||.|||||.. .|.       .. |.||||...| .     ..||.|.|....|.||||.|||..|.. ...... .|.... |..|.|.....
NCKKIGEGCYGEVFSVTWNG-------KEVVMKIIPIHWSCCKYYGEYCGEHQQTNDEALNEIIIMKKMGKLSHRNMCPNFPNFCGMCVVTQVPGKCCKK

FIKLWEKYDNEKGSENDHPELFGDNQLFAVLELKFAGSDMANF--KFLNSEQSYYALQQIILALAVGEEEYQFEHRDLHLGNILIE-YTNKKHIVCTFKS
. |.|..|.....||||.|..|..|||. ...... |....||  ||.. .|... ..|..........|.||.|.|||.||.||. .|.||.. .|.. 
LNKMWDHYCYTHHSENDRPDFFKKNQLHIHWIMEYGGRPLDNFRWKFNTCNQCISIMCQLVMSMYIAKDEMQFWHNDLHWGNVLIKRKTKKKWLHYTMDG

SNLTLLSKGVNVTIIDYTLSRVTINDCCYFNDLSRDEELFQATGDYQYDVYRMMRNELRNNWSSFSPKTNI
 . .. |.||.|||||...||.  .......|...||..|.  .|||.||||.||.. ...|. ...|...
KTIKIKSHGVMVTIIDFCKSRCGKDNKKIYWDWKNDETMFEQFWDYQFDVYRDMRKNCQHFWFVHHAKNWK
Kinase Haspin.AA DUF3635 477-566 42 1.6e-50 175.82 Pfam 1-121 (121) Show / Hide 
Range on Protein: 477-566
Range on HMM: 1-121/121
Sequence Identity: 42% (51 aa)

EELFQATG---------DYQYDVYRMMRNELRN--NWSSFSPKTNIIWLSYVIVKVLDSVKYKSI---NTKVHRMYIDKI-----------KELKNIIMT
...||..|         |||.|.|||||..| |  .||.|.|.||..||.|.|.|.|...|.|||   ||...|||..||           |....|.|.
HDFFQGKGKSKINEYQYDYQFDIYRMMRKMLKNPICWSQFHPMTNVLWLHYLIHKLLHKMKFKSICTENTAAMRMYMKKIINHHLMDPARHKHFHQIFMS

FESAS--HCANYLFNL----N
|||||  ||..||||.    .
FESASIRHCQHYLFNWVRQMK
Kinase Haspin.AA Ciliate-A9 248-265 50 9.6e-08 13.6 In-house 1-18 (392) Show / Hide 
Range on Protein: 248-265
Range on HMM: 1-18/392
Sequence Identity: 50% (9 aa)

LLNTKKIGEGAYGEVFRC
... |.|||||.| |. |
FEPIKIIGEGAFGCVIQC
Kinase Haspin.AA CDC2 249-269 47 5e-06 13.84 In-house 2-22 (301) Show / Hide 
Range on Protein: 249-269
Range on HMM: 2-22/301
Sequence Identity: 47% (10 aa)

LNTKKIGEGAYGEVFRCSRNQ
   .||||| ||.|..|  .|
QKIEKIGEGTYGVVYKCKDMQ
Kinase Haspin.AA CMGC 248-265 55 1.4e-05 13.29 In-house 1-18 (513) Show / Hide 
Range on Protein: 248-265
Range on HMM: 1-18/513
Sequence Identity: 55% (10 aa)

LLNTKKIGEGAYGEVFRC
  . ||||||.||.|..|
YEIIKKIGEGTYGVVYKC
Kinase Haspin.AA Fer 248-264 52 2e-05 14.59 In-house 1-17 (283) Show / Hide 
Range on Protein: 248-264
Range on HMM: 1-17/283
Sequence Identity: 52% (9 aa)

LLNTKKIGEGAYGEVFR
   .||.||||.|||..
VTLGKKLGEGAFGEVYK
Kinase Haspin.AA STE 248-313 21 0.000139 12.25 In-house 1-85 (359) Show / Hide 
Range on Protein: 248-313
Range on HMM: 1-85/359
Sequence Identity: 21% (19 aa)

LLNTKKIGEGAYGEVFRCSRNQEVLKDHISD-----------IVLKIIPLEGSTVINGE----------KQKTFSQILPEIIITKKM
. . .|||.||.|.|... ..     .  ..           .  |...|| ..  . |           .. . ||| || | ||.
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKC
Kinase Haspin.AA Ciliate-C6 248-265 27 0.000175 11.81 In-house 1-18 (306) Show / Hide 
Range on Protein: 248-265
Range on HMM: 1-18/306
Sequence Identity: 27% (5 aa)

LLNTKKIGEGAYGEVFRC
..  ...|.|..|.|. |
INYRDSLGSGSFGQVYKC
Kinase Haspin.AA TK 248-265 38 0.000279 9.41 In-house 1-21 (486) Show / Hide 
Range on Protein: 248-265
Range on HMM: 1-21/486
Sequence Identity: 38% (8 aa)

LLNTKKIGEGAYG---EVFRC
.   ||.|||..|   ||...
ITLGKKLGEGQFGSFGEVYKG
Kinase Haspin.AA CDK 249-265 47 0.000295 9.34 In-house 2-18 (284) Show / Hide 
Range on Protein: 249-265
Range on HMM: 2-18/284
Sequence Identity: 47% (8 aa)

LNTKKIGEGAYGEVFRC
   .|||||.||.|...
EKLEKIGEGTYGVVYKA
Kinase Haspin.AA PDK1 250-265 43 0.00032 8.26 In-house 3-18 (307) Show / Hide 
Range on Protein: 250-265
Range on HMM: 3-18/307
Sequence Identity: 43% (7 aa)

NTKKIGEGAYGEVFRC
. | ||||.|..|...
FGKNIGEGSYSTVYLA
Kinase Haspin.AA S_TKc 248-514 12 0.000641 -119.44 SMART 1-231 (231) Show / Hide 
Range on Protein: 248-514
Range on HMM: 1-231/231
Sequence Identity: 12% (40 aa)

LLNTKKIGEGAYGEVFRCSRNQEVLKDHISDIVLKIIPLEGSTVINGEKQKTFSQILPEIIITKKMCSLRTSKTNSTNGFVSIQKVSLVKGRYPPHFIKL
    .|||.||.|.|..|  .            .|||.                                            .. ... |    |. .||
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-----------------------------------------EHIRREIQILKK-HHPNIVKL

WEKYDNEKGSENDHPELFGDNQLFAVLELKFA--GSDMANFKF---------LNSEQSYYALQQIILALAVGEEEYQFEHRDLHLGNILIEYTNKKHIVC
 . ...              . |. |.|.     |. .   |          ..  .  . ..||..||.   .  .. ||||   |||.        .|
YDVFQD--------------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE---HIKIC

TFKSSNLTLLSKGVNVT-------IIDYTLSR---------VTINDCCY----FNDLSRDEELFQATGDYQYDVYRMMRNELRNN----WSSFSPKT---
 | .. .    . . .|       ..    ..         ...  ...    |     ....|.  |    ..  ..|. |. .    ..     .   
DFGLARQL---TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG--SPEAKDFIRKCLQKDPEKRPTA-EALQDEW

---NIIWL
   .  |.
DIKCHPWF