Gene SAK (Fruit Fly)

SAK

Species: Fruit Fly
Alias: SAK, SAK/PLK, SFO199, CG7186
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 78D5,

Classification

Group: Other
Family: PLK
Subfamily: SAK

Sequence

Name Sequence Type Origin Length Description Download
SAK.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 254 Kinase domain by global Sugen HMM Fasta, JSON
SAK.AA Protein Various 769 None Fasta, JSON

Protein domain

Protein domains of SAK.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SAK.AA SAK 14-267 74 2.9e-197 661.62 In-house 1-254 (254) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-254/254
Sequence Identity: 74% (188 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTET
|.|||||||||||.||.|.|.||||.||||||||||.|.||...|||.|||||..|||||.|.||..|.|.||||||||..||||.||||.|..|||||.
YQVQHLLGKGGFACVYRAKCIHTHQEVAIKMIDKKLMQKTGMVQRVRNEVEIHCQLKHPSILELYNYFEDNNYVYLVLEMCHNGEMHRYMKHRMRPFTEE

EAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVGRPPF
||.....|.|.|.||||||.|||||..|||.||.|.||.||||||||||||.|.|.|.||||||||||||...||.|||..||||.||||||||.|||||
EARHFMHQIVIGMLYLHSHGIMHRDLTLSNILLTRDMHCKIADFGLATQLKMPHEKHYTMCGTPNYISPEIATRTAHGLQSDVWSLGCMLYTLLIGRPPF

ETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFM
.||||..|||||.|.|||||||||.||||||.|.|.|.|||||||..|||||||
DTDAVKNTLNKVMMAEYIMPAHLSMEAQDLIHKMLRKNPHERITLSTVLCHPFM
Kinase SAK.AA PLK 14-267 47 4.8e-172 564.44 In-house 1-258 (258) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-258/258
Sequence Identity: 47% (123 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTET
||..|.||||||| .|.....||.| .|||...|.|.| ... ....||.|||..|.||.......||.|...||.|||..||..|..|....|...||.
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

EAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVV--SRTSHGLPADVWSVGCMLYTLLVGRP
|. ... |.| ||.|||.|.|.|||. |.||.|...|||||.||||||.|....||..|||||||||.|||.  ... |.. .|.||.||..||||.|.|
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFETDAVQSTLNKVVMSEYIMPAH--LSYEAQDLINKLLKKLPHERITLEAVLCHPFM
||||..|..|...... .|..|.|  .|.||.|||.|.|.. |.||.|....|.|||.
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF
Kinase SAK.AA Aur 14-267 37 4.6e-114 302.33 In-house 1-257 (257) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-257/257
Sequence Identity: 37% (96 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIA-RPFTE
 |.. .|||| |  || ||  .||. .|.|...|. |.  ..   .|.|..|.|.|.|| .|..|..|.|....||.|| | .||| ..    . . |.|
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

TEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSR-EMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVGRP
 .|| . .|.  .| |.|| ||.||||   |.||.  .  .||.||| ...  .  .| ||.|||  |..||.|.. .|.   |.|..| ..| |..|.|
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPN-NNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCP

PFET-DAVQSTLNKVV-MSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFM
|||  .  . |. ..  . .. .| |.| ||.|||.|.|.. |..|.||. .. ||..
PFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI
Kinase SAK.AA AGC 14-267 22 1.6e-106 275.86 In-house 1-395 (395) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-395/395
Sequence Identity: 22% (89 aa)

YEVQHLLGKGGFATVYKARCLHTH------QDVAIKMIDKKL-IQGTG--LTNRVRQE------------VEIHSRLK----------HPSVLQ-LYTFF
.|.  ..|||.| .|| .|  ...      .  |.|...||  |. .      ..  |             .| ....          || . . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDANY--VYLVLELAH---------NG-ELHRYMNH--IARPFTETEAASILKQ-------VVAGLLYLHS-HNIMHRD-ISLSNLLLSREMHVKIADFG
|| ..  .|.|.|..           | ||. .. .    . |.| .|  .. .       .| .| |||| ..| ||| . . |.|| .. |.|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LATQLKRPD--------------------------------------------------ERHMTMCG--TPNYISPEVVSRTSHGLPADVWS--VGCMLY
|...... .                                                  .|  |.||  ||.|..||..    .| ..| ||  .||..|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

TLLVGRPPFETDAVQ----------STLNKVV------MSEYIMP----------AHLSYEAQDLINKLLKKLPHERIT----------LEAVLCHPFM
 .|.|.|||  | .|           . .|.       . .  .|           ..| ||.|||.|||.| | .|..           | .  ||. 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase SAK.AA S_TKc 14-267 36 2.8e-101 343.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-231/231
Sequence Identity: 36% (97 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHN--GELHRYMNHIARP--
||.  ..|||.|..|||.|  .|.. ||||.|.          ...|.|..|... .|| . .|| .||| ...|.|.|.. .  |.|..|. .  |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGL-PADVWSVGCMLYT
   |.| .|.....|.. .| |.|||.|.|||.  .|.||..  |.||.|||||.||       .|.||||.|..|||.   ..|  ..|.||.||.|| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLC-------HPFM
.|.|.|||.   .| ...|..          | || |.|.|.|.| | .|.|   .|        ||..
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SAK.AA CAMK 19-267 23 1e-95 308.89 In-house 1-425 (425) Show / Hide 
Range on Protein: 19-267
Range on HMM: 1-425/425
Sequence Identity: 23% (98 aa)

LLGKGGFATVYKARCLHTH------------QDVAIKMIDKKLIQG-------------------------TGLTNRVRQEVEIHSR-------LKHPSV
 ||.|.|..|....  .|             | ||||.|||| ...                              .||.|.||...       |.|| .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LQLYTFFQDANY-------------------VYLVL---ELAHNGELHRY-MNHIA-----------------RPFTETEAASILKQVVAGLLYLHSHNI
..|| ...|..|                   .|.|.   |.. .|||  .  ..|                  . ||| ||. . .|.. .. |.|||||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDISLSNLLLSREM-----------------HVKIADFGLATQLKR-----------------------PDERHMTMCGTPNYIS-PEVVSR------
.|||. . |.||.  .                  .||.|||.|.....                       ...   |.|||| |.. |||...      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------TSHGLPADVWSVGCMLYTLLVGRPPFETD-------------AVQSTLNKVVMSEYI-MPAHLSY-----------------------EAQD
        . .| ..|.||.|..||..|.|.|||. |               . .. |.   .|   | ..|                        |..|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LINKLLKKLPHERITLEAVLCHPFM
||.|.|.. | .|.|.| .| ||.|
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase SAK.AA PLK-Unclassified 14-267 39 2e-95 323.31 In-house 1-264 (264) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-264/264
Sequence Identity: 39% (103 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHI------A
|.. |.||||||| .|..  . | .  |.| |.|  .. .    .  .| .||. |.|. . . ...| |  .||..||.  || |  |. ..       
YHRGHFLGKGGFAKCYQVKNIETKKIYAAKIIPKSSLTKNRARQKLISEIKIHKSLHHKNIVKFEHCFEDHENVYILLEYCPNGTLMEYIKRRNFQLFEK

RPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTS--HGLPADVWSVGCMLYT
   ||.|. ... |.| .| |||...| |||  | |..|.  | |||.|||||| |.   |.  | |||||||.||.       |.   |.|| ||.|||
KRLTEYEVKCYTYQIVQALKYLHQNRIIHRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHSYEVDCWSFGCILYT

LLVGRPPFETDAVQSTLNKVVMSEYIMP--AHLSYEAQDLINKLLKKLPHERITLEAVLCHPFM
||.|.|||||  |..|. |. . .|  |  .|.| .| ||| . |.  | .| |.   . |||.
LLIGKPPFETKDVKQTYKKIKCNQYSFPEPCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY
Kinase SAK.AA PLK1 14-267 40 3.2e-89 293.42 In-house 1-253 (253) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-253/253
Sequence Identity: 40% (104 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTET
||  . |||||||  |  |  .|.. .| |.. |.|.      ... ||..||  |.|. . ... || | ..||.|||| .   |   ..   .. || 
YEKGRFLGKGGFAHCYEIRDKDTKEVFAGKVVPKSLLIKQHQRDKMTQEIQIHRQLHHRHIVKFHHFFEDKQNVYIVLELCRRRSLME-LHKRRKAITEP

EAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVGRPPF
|.   ..|.| | .|||  .|.|||. | || |  ...||| ||||||..    || .|.||||||| |||.... |    |.||.||..|.||.|.|||
ECRYYMYQIVEGCQYLHNNKIIHRDLKLGNLFLNDHLQVKIGDFGLATKCEYDGERKKTLCGTPNYIAPEVLNKKGHSFEVDIWSIGCIMYILLFGQPPF

ETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFM
|| ... |  ..   || .| |.|  |..|| |.|.. |..| | |.||   |.
ETKCLKETYSRIKKNEYRIPSHISQPAAQLIRKMLDPDPTRRPTIEQVLNDEFF
Kinase SAK.AA CAMKL 14-267 29 1.4e-88 282.79 In-house 1-297 (297) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-297/297
Sequence Identity: 29% (89 aa)

YEVQHLLGKGGFATVYKARC-LHTHQDVAIKMIDKKLIQGTGLTNR------------VRQEVEIHSRLK---HPSVLQLYTFFQDANY------VYLVL
|..   ||||.|..|  |.  ..| . ||||.|||| |.    ...            .|.|..|...|.   || . .||  ... ..      .|||.
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELAHNGE--LHRYM-NHIA--RPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREM--HVKIADFGLATQLKR----PDERHMTMCGTPNYI
|.. .||  |. |  .|    ....| ||  . .|.|... |.|||.| |||| . |.||.  .   .||.|||.... ..    |..  .| ||.|.| 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

SPEVVSR--T-SHGLPADVWSVGCMLYTLLVGRPPFE---------TDAVQSTLNKVVMSEYI-MPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFM
.||....  .  .| ..|.|| | .||....|. ||.         ..     . . .  .|.  . |.| ...||| |.|.. | .|.|.. .. ||.|
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase SAK.AA Pkinase 14-267 30 6.1e-86 296.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVR-QEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNG----ELHRYMN-HIA
|..   .|.|.|..|||..   | . ||.| |.|. .    . ...| .|..|. ||.|| ...|| .|.| ...|.|.|.. .|    .|..|.  .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RPF--TETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHV----KIADFGLATQL-KRPDERHMTMCGTPNYISPEVVS-RTSHGLPADVWSV
..|  .| |. ....|.. || |.||..|.|||. ..|.|.....|.    ||.||||| |.   ...  .| ||||.|..|||.  .. .| ..|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GCMLYTLLVGRPPFETD------AVQSTLNKVVMSEYIMPAHLS---------------------YEAQDLINKLLKKLPHERITLEAVLCHPFM
||.|| .| |||||  .        .  .... . ..  .   .                      |..|.|...|.| |..|.| | .|.||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase SAK.AA ULK 14-267 26 6.9e-82 278.36 In-house 1-329 (329) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

YEVQHLLGKGGFATVYKARCLHTH----QDVAIKMIDKKLIQGTG-------LTNRVRQEVEIHSRLK--------HPSVLQLYTFFQDA--NYVYLVLE
|.. | |||| |..|||.|.  |.    ..||.|||||. ..          . . ...|..|  .||        || . .|| .|...  |..|...|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LAHNGELHRYMNHIAR---------PFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSRE------------MHVKIADFGLATQLKRP---DE
.   | |  |..   .          ..| || ...|| ..|. .||.|||.|||| ..| |..              ...||||||.| ..  .   ..
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

RHMTMC------GTPNYISPEVVS----RTSHG-LPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMP--------------------AHLS
  ||.       ||| | .|....    .  ..   .|.||.||..| .|.|.|||..   ... .. .....  |                     ..|
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

YEAQDLINKLLKKLPHERITLEAVLCHPFM
 | .||| ..|.. . .||. | .. ||..
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase SAK.AA ULK 14-267 26 2.7e-77 263.1 In-house 1-324 (324) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-324/324
Sequence Identity: 26% (88 aa)

YEVQHLLGKGGFA-TVYKARCLHTH---QDVAIKMIDKKLIQGTGLT-------NRVRQEVEIHSRLK---HPS--VLQLYTFFQDA--NYVYLVLELAH
|.. | |||| |. .|||.|.  |.   |.||.|||||| ..   .        .  ..|..|   ||   ||   . .|| .|...  |..|...|.  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELHRYMNHIAR--------PFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSR------------EMHVKIADFGLATQLK---RPDERHMT
 | |  |..   .         ..| || ...|| ..|. .||.|||.|||| ..|.|..             . ..||||||.| ..      .   .|
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

MC------GTPNYISPEVVS----RTSHG-LPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSE-----------------YIMPA---HLSYEAQ
..      ||| | .|....    .  ..   .|.||.||..| .| |..||...  ... .. ....                 . .|    ..| | .
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLY-IQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECK

DLINKLLKKLPHERITLEAVLCHPFM
||| ..|.. . .||. | .. ||..
DLIRRMLQYDEKDRISWEEIFNHPWF
Kinase SAK.AA Pkinase_Tyr 14-160 29 4.2e-23 78.87 Pfam 1-158 (270) Show / Hide 
Range on Protein: 14-160
Range on HMM: 1-158/270
Sequence Identity: 29% (48 aa)

YEVQHLLGKGGFATVYKARCL----HTHQDVAIKMIDKKLIQGTGLTN----RVRQEVEIHSRL-KHPSVLQLYTFFQ-DANY--VYLVLELAHNGELHR
 .  . ||.| | .|||...      |...||.||. |    |.   .       .|..| . | .|| ...||     .     .|.|.|.. .| |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD

YMNHI---ARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLA
|        .|.|  .  ..  |. .|. ||.|.|. |||.   | |......|||.|||||
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase SAK.AA TyrKc 14-267 21 5.6e-16 35.67 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-267
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

YEVQHLLGKGGFATVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRL--KHPSVLQLYTFFQDA-------NYVYLVLELAHNGELHRYM-
 .  . || | | .|||..     ..||.||. .            ..| .| ..|  .|| ...||    .          ...|.|.. .| |. |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

NHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSREMHVKIADFGLATQLKRPD-----ERHMTM----CGTP----NYISPEVVSRTSH
.|  . ..  .  |.  |. .|  ||||.|. |||.   | |.... .|||.||||.  ..  |     .   ..    .|         .||.      
KHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

GLPADVWSVGCMLY---TLLVGRPPFET-----DAVQSTLNKVVMSEYIMPAHL---------SYEAQDLINKLLKKLPHERITLEAVLCHPFM
    |||| | ...   |.  | .| .         |  ...|   .. .. .          . |  ... .  .  |..| | ...  | ..
TTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF