Gene CG3216 (Fruit Fly)

CG3216

Species: Fruit Fly
Alias: SFO061, GYC, CG3216
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 57C1,

Classification

Group: RGC
Family: RGC

Sequence

Name Sequence Type Origin Length Description Download
CG3216.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 271 Kinase domain by global Sugen HMM Fasta, JSON
CG3216.AA Protein Various 1152 None Fasta, JSON

Protein domain

Protein domains of CG3216.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ANF_receptor CG3216.AA ANF_receptor 107-481 23 1.3e-83 288.93 Pfam 1-364 (364) Show / Hide 
Range on Protein: 107-481
Range on HMM: 1-364/364
Sequence Identity: 23% (97 aa)

RCGPAVDLALDEINK---VFLKPHNITLLKKKGSYPSCSGARAPGLAADMYFQDD-VIAFIGPACAFALEPVARLAAYWNKPIITGMGDQPPSSEGELTV
.|.||...|...||.   ..|.......      |  ||   ... |||.... . | |.||| |  . .||||.|..||.|.|.               
QCAPAMRMAIEDINADPGILLPGITLGYHDDDCCY--CSDC-QAVAAADCCWH-KGVVAIIGPSCSYVCIPVARIANHWNIPMISW--------------

TSGILGRIHKWKNENTGMFKD-KSKYPTLTRMSYCQCRL-ILVFASVIRQ-FNWNHVALLVDRSEL-FSWTV---GKNLEYGLRQEG---LLS---FVKE
              ....  . |..||...|       . . .... |.  |.|..||...| ..  .....    . ..  ||..|   ...    ...
-----------GCTCPCLTDKAKNRYPYFFRTVPSDTYQYGWAMVDIIQHHFGWKWVAVIYDDDDYYYWRGGCYFMEAFQDELREHGGNCVYYAYVSMVI

LNGNEEEVYENYLKD-ASMYARVVILSVRGVLV----RKFMLAAHSLGMTNGEWVFLDVEIFQSEYWGDKGWEMKDEHDAKARKAYEALLRVSLLQPTSP
 . .... |.  .||  .| |||...   . ..    | .|..|| |||..|..|.. .... . |...  |...|....|.|.|... | . .  | ||
PWDDDFMDYLKKIKDIIKMKARVIVMCCYPDDMGLLQRQIMQQAHELGMMSGGYVWIYTDWWMHSYDMQ-WWYDDDMDNDKFREAMKGVLGFTMH-P-SP

KFQDFADNVRENALYDYNYTFGEGEEVNFFIGAFYDGVYLLGMALNETLTEGGDIRDGV---------NITRRMWN-RTFEGITGHVRIDDNGDRDADYS
.||.| .....           ...|.|.. . .||.|||...||...|...... .|          .....||| ..|||.||.|..||||.| .||.
EFQEFMQRWKK-----------TDTEMNYYAAYAYDAVYLYAHALHNMLRCDPNHWNGGCDIMKWHGWQLLHYMWNKVNFEGVTGDVQFDDNGGRRPDYM

ILDLDPI
  .....
YWIMNWD
Kinase CG3216.AA RGC 626-872 38 1.1e-128 433.84 In-house 1-300 (300) Show / Hide 
Range on Protein: 626-872
Range on HMM: 1-300/300
Sequence Identity: 38% (116 aa)

KGERVAIKKVNVK----KVDLTPQLLWEIKQARDVSHENTVRFVGACIDLP----RPTVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNY
.|..|.|||.| .    ..|.|.. ..|.|| |.. |.| ..|.|.||| |     ....|..||||||||.|.|||. |..||.|..|.|.||||||.|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHNSDVAAHGKLRSCNCLIDGRFVLKISDFGL-----RTLTTPSD----------FVRDQ---NYYLKLLWIAPELLPLTTIPGCCPA-------TQRGD
||.| .  ||.|.|.||..|.|.|.||.||||     ....  ..          ..|..    || |.|| |||.|. ...|.....       ||.||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFGIILEEIVNRGG-----PYQE-----ARQQMDVHTILHKVRQCNG---FRPLIRER------ECPPDLLELMEKCWADNQEERPT-FSTIRSNIRT
|||||||. ||. |.|     |...     ..  |... ..... ...|   |||.|.|       ||.|.||.||..||| . ||||. |..||....|
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase CG3216.AA RGC 626-872 38 1.1e-128 433.84 In-house 1-300 (300) Show / Hide 
Range on Protein: 626-872
Range on HMM: 1-300/300
Sequence Identity: 38% (116 aa)

KGERVAIKKVNVK----KVDLTPQLLWEIKQARDVSHENTVRFVGACIDLP----RPTVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNY
.|..|.|||.| .    ..|.|.. ..|.|| |.. |.| ..|.|.||| |     ....|..||||||||.|.|||. |..||.|..|.|.||||||.|
EGDWVWIKKHNQRNLFRHWDFTRSMMRELKQMRQLQHDNLNKFIGMCIDPPMEYHPGNMCIVWEYCSRGSLQDILENDDIKMDWMFKYSFIRDIVKGMQY

LHNSDVAAHGKLRSCNCLIDGRFVLKISDFGL-----RTLTTPSD----------FVRDQ---NYYLKLLWIAPELLPLTTIPGCCPA-------TQRGD
||.| .  ||.|.|.||..|.|.|.||.||||     ....  ..          ..|..    || |.|| |||.|. ...|.....       ||.||
LHHSPIRYHGNLKSWNCVVDSRWVVKITDFGLNNPLCHWFKHGQINPPCKSDDKSWQRQHDEHPYYKKMLWTAPEHLREWRMPHQWGPHRQTQRGTQKGD

VYSFGIILEEIVNRGG-----PYQE-----ARQQMDVHTILHKVRQCNG---FRPLIRER------ECPPDLLELMEKCWADNQEERPT-FSTIRSNIRT
|||||||. ||. |.|     |...     ..  |... ..... ...|   |||.|.|       ||.|.||.||..||| . ||||. |..||....|
VYSFGIIMYEIITRKGPWDLEPFCMWPGEYELSPMEIIEEVKYPPKKGGQKPFRPSIHEDEEGHMIECNPCLLHLMRDCWAEDPEERPDMFDQIRKQLKT
Kinase CG3216.AA TKL 623-870 22 7.3e-53 181.94 In-house 12-364 (364) Show / Hide 
Range on Protein: 623-870
Range on HMM: 12-364/364
Sequence Identity: 22% (81 aa)

GQFKGER----------VAIKKVNVKKVDLT---------------------------PQLLWEIKQARDVSHENTVRFVGACIDLP-----------RP
|...|..          ||.|| ... .|..                            ..  ||.. .  .|.| |.|.|.|.. |            .
GKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWG

TVLILTEYCSRGS-LKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDV-------AAHGKLRSCNCLIDGRFV--------------LKISDFGLRTL
   | .|||..|| | ...        |. |.....|| .||||||...         .|  | | |.|.|  .               .||.|||| . 
QLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRF

TTPSDFVRDQ---------------NYYLKL---LWIAPELLPLTTIPGCC----------PATQRGDVYSFGIILEEIVNRGGPYQEARQQMDVHT---
 ..|    |.               . . .     | |||.|  ..   ..          ..... |||||||.| ||. |  ||..    . .     
MSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPF

-ILHKVRQCNGFRPLIR-----------ERECPPDLLELMEKCWADNQEERPTFSTIRSNI
 .  ...  .| ||.|            .  |||.. .||..||. . |.||.|..| . .
EEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase CG3216.AA TKL-Unique 623-870 28 4.2e-49 169.46 In-house 16-290 (290) Show / Hide 
Range on Protein: 623-870
Range on HMM: 16-290/290
Sequence Identity: 28% (82 aa)

GQFKGERVAIKKVNVKKVDLTPQLLW----EIKQARDVS-HENTVRFVGACID--LPRPTVLILTEYCSRGSLKDVLE---------NEAIELDWNFRMS
| ..|. ||||. .. . |. ....     |..       |.| |...|.|.|   . |   | .|||..||| |||          |. ..|... |..
GKWRGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVK

LIHDIVKGMNYLHNSDV-AAHGKLRSCNCLIDGR-----FVLKISDFGLRTLTTPS--DFVR------DQNYYLKLLWIAPELLPL--TTIPGCCPATQR
...||..||.|||...   .|..|.| | |.| .     .  ||.||||... . .   ...      .|     ..|.|||.|    ...      .. 
MAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQY------SEK

GDVYSFGIILEEIVNRGG------PYQEARQQMDVHTILHKVRQC-NGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNI
 |||||||.| ||..|        |||.    ||   .. .|..   ..|| | . .||... .|...||... ..||.|..|.. .
SDVYSFGIVLWEIATRKITKTYKKPYQG----MDQEQWCEMVHYMEENYRPPIPN-HCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase CG3216.AA TK 625-870 15 3.5e-34 111.41 In-house 19-486 (486) Show / Hide 
Range on Protein: 625-870
Range on HMM: 19-486/486
Sequence Identity: 15% (74 aa)

FKG-------------------------------ERVAIKKVNVK-KVDLTPQLL---------------WEIKQARD---VSHENTVRFVGACIDLPR-
.||                               ..||.| .  .   . . ...               .|. .  .     |.| ||..|.| .    
YKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEPK

---------PTVLILTEYCSRGS----LKDVLENEAIE--------------------------------------------------------------
         . ..|..||.. |.    |.| | .   .                                                              
PCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDLL

-------------LDWNFRMSLIHDIVKGMNYLHNS-----------DVAAHGKLRSCNCLIDGRFV-----------LKISDFG---------LRTLTT
             |.   ..   ..| .|| |||             |.||.      |||.. . |            ||.|||          | .  
QMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAAR------NCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYS

PSDFVRDQNYY------------------------LKLLWIAPELLPLTTIPGC---CPATQRGDVYSFGIILEEIVNRG-GPYQEARQQMDV------H
 .| .|...|.                        | . | ||| |   .   .      |   ||.|||. . ||. .| .|| .     ||      .
DDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQ

TILHKVRQC-----------NGFRPLIRERECPP-------------DLL-ELMEKCWADNQEERPTFSTIRSNI
 .. ..|.             .  .. .   ||.             ... .|| .||. . |.|||||.... .
EVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase CG3216.AA TK-Unique 623-870 24 8.9e-28 92.93 In-house 26-294 (294) Show / Hide 
Range on Protein: 623-870
Range on HMM: 26-294/294
Sequence Identity: 24% (68 aa)

GQFKGERVAIKKVNVKKVDLT-PQLLWEIKQARDVS-HENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIE----------------------
...|  .||.|... .  |..  ..| ||.. . .  |.| |...|.|..     ..|. |||..|.| . | . . .                      
HWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD-EPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPR

---LDWNFRMSLIHDIVKGMNYLHN--SDVAAHGKLRSCNCLIDGRFVLKISDFGLRT-LTTPSDFVRD-QNYYLKLLWIAPELLPLTTIPGCCPA-TQR
   ..  .  . . .| .||.||.     .  |. | . |.|. ...|.||.|||. . . |. . ..  .   . . | ||| |  .      .. | .
TEPISPKDLYHFAWQIACGMEYLASQRKKI-VHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCY----HGMYHTTK

GDVYSFGIILEEIVNRGG-PYQEARQQMDVHTILHKVRQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNI
.||.|||... ||.  |. || . ..      |. ..|.  |.|.. .|  |.... .||. || .. ||||.|..|.. .
SDVWSFGVLMWEIFTLGACPYPGMPWKD----IMECIRD--GYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase CG3216.AA RIPK 627-870 25 3e-27 89.88 In-house 18-290 (290) Show / Hide 
Range on Protein: 627-870
Range on HMM: 18-290/290
Sequence Identity: 25% (72 aa)

GERVAIKKVNVKKVDLT------PQLLWEIKQARDVSHENTVRFVGACIDL---PRPT-VLILTEYCSRGSLKDVLENEA----IELDWNFRMSLIHDIV
|..||.| .. |... .       ....| |      .|. |.  | |..      .  . | .||   ||| ..|  .       . |  |  .|| |.
GDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEIS

KGMNYLHNSD-VAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQN-----YY----LK---LLWIAPELLPLTTIPGC-CPATQRGDVYSFGI
 ||.|||. . .  |  |   | |.|. |  ||.|||| |  . |    |.      |     ..   |  ..||.. .|  .     .|   |||||.|
CGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHF-RTDNKKPIKVVTPKYDVYSFAI

ILEEIVNRGGPYQEARQQMDVHTILHKVRQCN-GFRPLIRE--RECPPD-----LLELMEKCWADNQEERPTFSTIRSNI
.. |.  .  ||       |. ......  |. | || . .  ...| .     . |||..||. . ..||.|  ... .
VMWEVLTQKHPYE------DRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase CG3216.AA DRK 617-751 33 5.5e-27 88.46 In-house 14-148 (258) Show / Hide 
Range on Protein: 617-751
Range on HMM: 14-148/258
Sequence Identity: 33% (46 aa)

QVYTTIGQFKGERVAIKKVNVKKVD---LTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVK
.|..  |   |  ||.|.     ..   .   .  ||       | | . | |.|   | .  .| .|| .||||  .| .|.||.||  ....  |. |
EVFR--GTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDI--CICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAK

GMNYLHNSD-VAAHGKLRSCNCLIDGRFVLKISDFGLRT
||.|||... .  |  | | | |.|  .  |..|||| |
GMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLST
Kinase CG3216.AA MLK 623-751 26 1.4e-24 82.25 In-house 18-181 (291) Show / Hide 
Range on Protein: 623-751
Range on HMM: 18-181/291
Sequence Identity: 26% (44 aa)

GQFKGERVAIKKVNVKKVDLTP-----------QLLWEIKQARDVSHEN----TVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEA-----------
|.......  | | ||.|. ..           ..  |....| .||.|     ..|.|.|.. | . ..|..|||. ||| .|| ..            
GRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQK

--IELDWNFRMSLIHDIVKGMNYLHNSDV--AAHGKLRSCNCLID------GRFVLKISDFGLRT
  .  |  . |.  ... .||.|||. ..    |  | | | |||      .  .|||.|||. .
NDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR
TyrKc CG3216.AA TyrKc 594-870 23 9e-17 48.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 594-870
Range on HMM: 1-280/280
Sequence Identity: 23% (79 aa)

ISLQ------QFG-IHSGRASIASFTSLPPQVYTTIGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARDV--SHENTVRFVGACIDLPR-----PTVLIL
|.|       .|| .. |...                    . ||.|...  .      .. |..  . .  .|.| ||..|.|..  |     . ..|.
ITLGKKLGEGAFGEVYKGTWK--------------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

TEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSC--------NCLIDGRFVLKISDFGLRTLTTPSDFVRDQ-------NY
.||.. |.||| | .   .| .    |  ..| .||.|||            |        |||.. ... |||||||      | .. |         |
MEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK---------NCIHRDLAARNCLVGENHTVKISDFGL------SRDIYDDDQQGESKDY

YLK----LL-------WIAPELLPLTTIPGCCPATQRG------DVYSFGIILEEIVNRGGPYQEARQQ--MDVHTILHKVRQCNGFRPLIRER------
| |             | ||| .            . |      ||.|||. . ||  .|..  .   |  |.   ....|.|  |.|. . .       
YRKKEHKGGKTMLPIRWMAPECI------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQ--GYRMPQPPNDYPMSF

-ECPPDLLELMEKCWADNQEERPTFSTIRSNI
 .||... ..|..||. . |.|||||.|.. .
VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase CG3216.AA TKL-ciliate2 728-871 31 2.3e-15 47.22 In-house 144-273 (273) Show / Hide 
Range on Protein: 728-871
Range on HMM: 144-273/273
Sequence Identity: 31% (47 aa)

KLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVR-DQNYYLKLL----WIAPELLPLTTIPGCCPATQRGDVYSFGIILEEIVNRGGPYQEARQQMDVHTI
|. | | |.|  |  |..|||          |. . ||    .    |.||| .           | . ||.|..||| ||  |  || . . .     .
KINSLNVLVDDNFRCKLTDFGWTR-------VKPQDNYMTNKIGTYQWMAPEVIKAFYY------TEKADVFSYSIILWEIASREPPYRNKKGDVVAEKV

LHKVRQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNIR
.     ||  || |  ..|||.. .||..|| .||. ||.|  |  .. 
M-----CNNLRPTI-PKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
S_TKc CG3216.AA S_TKc 611-874 18 1.3e-14 37.27 SMART 1-231 (231) Show / Hide 
Range on Protein: 611-874
Range on HMM: 1-231/231
Sequence Identity: 18% (53 aa)

FTSLPP-------QVYTTIGQFKGERVAIKKVNVKKVDLTPQLLWEIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSR--GSLKDVLENEAIE---
.. | .       .||  .    |..||||...        ... ||.  .   |.| |.. ... |     . . .|||.   |.|.|....   .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFGLRTLTTPSDFVRDQNYYLKLLWIAPELLPLTTIPGCCPATQ-RGDVYS
  ..     .... |.....|.|.  .  |  |   | |.|   ..||.|||| ..           .   . ..|||.|         . .  . |..|
FPFPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---------GYGKCKCDWWS

FGIILEEIVNRGGPYQEARQQMDVHTILHKVRQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRS-----NIRTIM
.|.|| | . .  |..      .......|..              .|.......||.  . |.|||   .       ..   .
CGCILYEMLCGYPPFP------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase CG3216.AA Pkinase_Tyr 654-749 33 8.4e-13 43.98 Pfam 58-157 (270) Show / Hide 
Range on Protein: 654-749
Range on HMM: 58-157/270
Sequence Identity: 33% (34 aa)

RDV-SHENTVRFVGACIDLPRP-TVLILTEYCSRGSLKDVLENE---AIELDWNFRMSLIHDIVKGMNYLHNSDVAAHGKLRSCNCLIDGRFVLKISDFG
.   .|.| ||..|.|.|  .|  ..| .||.  |.|.| | .       |.     .  ..| |||.||..     |  |.  |||..  .| ||.|||
KQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFG

L
|
L
Kinase CG3216.AA TKL-ciliate2 658-722 43 1.6e-12 37.53 In-house 55-117 (273) Show / Hide 
Range on Protein: 658-722
Range on HMM: 55-117/273
Sequence Identity: 43% (28 aa)

HENTVRFVGACIDLPRPTVLILTEYCSRGSLKDVLENEAIELDWNFRMSLIHDIVKGMNYLHNSD
| | | |.||| . |     |. ||| ||||  .| |. . | |  |  .  || .|. ||| |.
HPNIVMFLGACTKIPN--FCIIMEYCQRGSLWSLLQNQDVRLTWEDRRRIALDIARGVHYLHSSN
Kinase CG3216.AA Pkinase_Tyr 792-870 31 8.4e-12 40.6 Pfam 196-270 (270) Show / Hide 
Range on Protein: 792-870
Range on HMM: 196-270/270
Sequence Identity: 31% (26 aa)

DVYSFGIILEEIVNRG-GP-YQEARQQMDVHTILHKV-RQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNI
||.|||. . ||. .|  | |..    |. . ..... ..  | | . . . ||... .|| .||. . |.||||| |.. .
DVWSFGVLMWEIFTYGEQPTYPG----MSNEEVYEYIYED--GYR-MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase CG3216.AA MLK 792-870 30 2.9e-11 35.43 In-house 218-291 (291) Show / Hide 
Range on Protein: 792-870
Range on HMM: 218-291/291
Sequence Identity: 30% (24 aa)

DVYSFGIILEEIVNRGGPYQEARQQMDVHTILHKVRQCNGFRPLIRERECPPDLLELMEKCWADNQEERPTFSTIRSNI
||.|.|..| |.. |  ||.   | .|  .|. .| . .  .|.. .  ||. . .||..|| .. ..||.|. | .  
DVWSWGVVLWEMLTREVPYK---QHYDPMAIAWWVAYNGLRPPIPST--CPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase CG3216.AA Pkinase 627-720 20 1.8e-09 34.59 Pfam 24-126 (293) Show / Hide 
Range on Protein: 627-720
Range on HMM: 24-126/293
Sequence Identity: 20% (21 aa)

GERVAIKKVNVKKVDLTPQ--LLW--EIKQARDVSHENTVRFVGACIDLPRPTVLILTEYCSRG----SLKDVLE-NEAIEL--DWNFRMSLIHDIVKGM
|..||.|...... .   .  ...  ||.  . ..|.| ||. ... |  .. . . .|||  |    .|.|...  .   .  ...   . .  |..|.
GKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGL

NYLHN
.|.|.
EYCHS
Kinase CG3216.AA Pkinase 770-870 13 2.5e-07 27.02 Pfam 177-293 (293) Show / Hide 
Range on Protein: 770-870
Range on HMM: 177-293/293
Sequence Identity: 13% (17 aa)

WIAPELLPLTTIPGCCPATQRGDVYSFGIILEEIVNRGGPYQEA---RQQMDVHTILHKVRQCNGFRPLIRERECP-----------------PDLLELM
..|||..      |. . ... |..|.|.|| | ...  |....      .|   .. .....   ..   ... .                 .......
YMAPEVIR-----GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFI

EKCWADNQEERPTFSTIRSN--I
..|.. . ..|||.  |     .
KWCLCKDPKKRPTAEQILQHPWF
Kinase CG3216.AA DRK 792-811 60 1e-05 15.39 In-house 184-203 (258) Show / Hide 
Range on Protein: 792-811
Range on HMM: 184-203/258
Sequence Identity: 60% (12 aa)

DVYSFGIILEEIVNRGGPYQ
|||||.|.| |.| |  ||.
DVYSFAIVLWECVTRQDPYF
Kinase CG3216.AA DRK 841-872 28 0.002047 7.47 In-house 227-258 (258) Show / Hide 
Range on Protein: 841-872
Range on HMM: 227-258/258
Sequence Identity: 28% (9 aa)

CPPDLLELMEKCWADNQEERPTFSTIRSNIRT
|||    ||  ||  .   ||..  .   .  
CPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase CG3216.AA Pkinase 733-749 47 0.217911 5.99 Pfam 138-158 (293) Show / Hide 
Range on Protein: 733-749
Range on HMM: 138-158/293
Sequence Identity: 47% (10 aa)

NCLIDGRFVL----KISDFGL
|.||| . ..    ||.||||
NILIDNNGHIDACVKICDFGL
CYCc CG3216.AA CYCc 909-1103 46 1.4e-108 367.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 909-1103
Range on HMM: 1-231/231
Sequence Identity: 46% (107 aa)

LEKQRTEELLYQILPRPVAQQLMAG-DLVEPEEFSSVTIYFSDIVGFTELCARSSPMDVVNFLNDLYSTFDRIIGFYD-----VYKVETIGDAYLVVSGL
 |||....||.|.||| ||.||..| . |.|.....|||.|.||||||.||....||.|||.|||.|. |||||. ..     .|||||||||| ||||.
MEKQKNDRLLCQMLPRHVANQLKQGRHPVWPPCYDCVTILFTDIVGFTNLCSWCTPMQVVNMLNDHYTRFDRIIDRHGCYHNYCYKVETIGDAYMVVSGC

PEPNGD-------------------KHAREIALMALDILRAVSSFNLRHK----PEYKIQIRIGMHSGSVCAGVVGKKMPHYCLFGDTVNTASRMESTGQ
|..|..                    ||..||..|||.. .. .|...|.    |......|||.|.|.|..|||| .||.||.||||||.|||||||| 
PTRNEHNQCQCLHHWWTWCFWCFHWQHAQWIADWALDMVECMKTFHVQHHMGELPWNPLRMRIGIHTGPVVCGVVGIRMPRYCYFGDTVNMASRMESTGD

PGKIHVSSATKAIL-------DKFGTFQMEQ
||.||||..|. .|        ..|.|. |.
PGQIHVSEETYWCLCLDQFERRRCGQFEFEP
Guanylate_cyc CG3216.AA Guanylate_cyc 936-1122 45 2.1e-99 341.32 Pfam 1-214 (214) Show / Hide 
Range on Protein: 936-1122
Range on HMM: 1-214/214
Sequence Identity: 45% (97 aa)

VEPEEFSSVTIYFSDIVGFTELCARSS----PMDVVNFLNDLYSTFDRIIGFY--DVYKVETIGDAYLVVSGLPEP-----NGDKHAREIALMALDILRA
|..... .|||.|.||||||..|.|.|    || .|..|||.|..|||... .  ..|||.||||.|..|||||.|     ..  ||. .| ||||.. .
VYAQRYDCVTIMFADIVGFTAFCSRCSMNNMPMQCVRMLNDHYTCFDRLCDQHKFGCYKVKTIGDCYMCVSGLPPPCVQWCCCWHHAWCMADMALDMMEY

VSSFNLRHKPEYK-----IQIRIGMHSGSVCAGVVG--KKMPHYCLFGDTVNTASRMESTGQPG--KIHVSSATKAILDKFGTFQME----QRGDVELKG
....|  |..        ||.|||.|.|.|.|||.|   .||.||..|||||.||||||||.||  ||||| .|...| . ..||.|     ||....||
CQQVNVHHFNREPPTWNCIQMRIGIHTGPVVAGVIGSFQRMPRYCVWGDTVNVASRMESTGVPGSCKIHVSEETYRCLKCHENFQFECHLQHRGEIPVKG

KGT---VTTYWLNS
||    ..||.|. 
KGKMGEMETYFLHG
HNOBA CG3216.AA HNOBA 901-930 43 8.7e-10 36.95 Pfam 205-234 (234) Show / Hide 
Range on Protein: 901-930
Range on HMM: 205-234/234
Sequence Identity: 43% (13 aa)

EEKTRQLSLEKQRTEELLYQILPRPVAQQL
|. .| |  ||..|..|||...|..||..|
EQMHRELEEEKKKTDDLLYSMFPKSVANRL