Gene Ror (Fruit Fly)

Ror

Species: Fruit Fly
Alias: CG4926, ROR, DRor, DmHD-2, Dror, Ror, SFO102, HD-2
External Links: Flybase Link ,
Annotation: Drosophila polytene location: 31B4

Classification

Group: TK
Family: Ror

Sequence

Name Sequence Type Origin Length Description Download
Ror.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 264 Kinase domain by global Sugen HMM Fasta, JSON
Ror.AA Protein Various 685 None Fasta, JSON

Protein domain

Protein domains of Ror.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
KR Ror.AA KR 235-312 36 3.7e-36 127.35 SMART 1-90 (90) Show / Hide 
Range on Protein: 235-312
Range on HMM: 1-90/90
Sequence Identity: 36% (33 aa)

ENCYWE--DGSTYRGVANVSASGKPCLRWSWLMKEISDF-----PEL-----IGQNYCRNPGSVENSPWCFVDSSRERIIELCDIPKCAD
..|||.  .| .||| .|...||.||.||.. .  . .|     |..      ..||||||.  ...|||... .. |. | ||||.|.|
RDCYWGDDNGESYRGTVNTTWSGHPCQRWDSQYPHLHWFYPEWFPCAGQLGLLEHNYCRNPDGDSEGPWCYTMDPNVRDWEYCDIPQCED
Kringle Ror.AA Kringle 237-310 36 3.9e-21 74.86 Pfam 1-85 (85) Show / Hide 
Range on Protein: 237-310
Range on HMM: 1-85/85
Sequence Identity: 36% (31 aa)

CYWEDGSTYRGVANVSASGKPCLRWSWLMKEI-SD-FPE-----LIGQ---NYCRNPGSVENSPWCFVDSSRERIIELC-DIPKC
||...| .||| .... ||.||.||.  .    .  .||       |.   ||||||   |. |||..    .   | | |||.|
CYHGNGENYRGTWSTTESGRPCQRWDSQTPHRHPFYTPENFPCKGLGEGKHNYCRNPDGDERGPWCYTQTDPRVRWEYCSDIPRC
Kinase Ror.AA Ror 410-673 61 1.5e-220 738.97 In-house 1-278 (308) Show / Hide 
Range on Protein: 410-673
Range on HMM: 1-278/308
Sequence Identity: 61% (172 aa)

VEFLEELGEGAFGKVYKGQLLQPN--KTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSP--
|.|.|||||..|||||||.|..||  .....||||..|..||....|||..||.|...|.|.||||.|||.....|||||||||..||||||||..||  
VRFMEELGECQFGKVYKGHLMGPNFMYHCMAVAIKTCKHDASPAQWQDFRQEIMLMATLHHPNIVCLLGVCTMDQPYCMLFEYMNHGDLHEFLIMRSPHS

----------TEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTT
          ....||....||.||.||..||.|||.||.||||||||||||.|...||||||||.||||||||||.|.||..|.|||..|.|.||||..
DHGCSSDDDRMVKSSLDHPDFLHIAIQIAAGMEYLSSHHFVHRDLAARNCLVGEHHHVKISDFGLMRDIYSSDYYRMQHKSWMPIRWMSPEAIMYGKFSE

ESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKTW
.||.||||||||||.|||||||||.||||||..||.|.||..|.||||..||||||||||....||.|.||..||..|
DSDIWSFGVVLWEIWSYGMQPYYGYSNQEVIEMIRNRHLLPCPHNCPTWIYSLMIECWHEIPSRRPRFKDIHSRLRSW
Kinase Ror.AA Pkinase_Tyr 410-670 47 1.4e-148 503.88 Pfam 1-270 (270) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-270/270
Sequence Identity: 47% (130 aa)

VEFLEELGEGAFGKVYKGQLL-QPNKTTITVAIKALKENASVKT--QQDFKREIELISDL-KHQNIVCILGVVL-NKEP--YCMLFEYMANGDLHEFLIS
..|...|||||||.|||| .  .| .|.|.||.| |||.|. .   ..|| ||... . | .|.|||. .||..  .||  ... .|||..|||...| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

NSPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYY-RVQSKSLLPVRWMPSESILYGKFTTESDVWS
.. .....|.  . ||...||..||.||......|||||||||||.|..||||.||||.||||. ||| |..... ||..||. |.| ||||||.|||||
HR-EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGVVLWEIYSYGMQP-YYGFSNQEVINLI-RSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRL
|||..|||..||.|| |.| ||.||...| .... . .|||||  .|.|| .|||..  .||||..| ..|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase Ror.AA TyrKc 410-670 43 1.3e-147 497.63 SMART 1-280 (280) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-280/280
Sequence Identity: 43% (129 aa)

VEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDL--KHQNIVCILGVVLNK-------EPYCMLFEYMANGDLHEFL
......|||||||.||||..       |.||.| |||.|    ..|| ||... . |  .|.|||...||.. .       ||.....|||..|||...|
ITLGKKLGEGAFGEVYKGTWK------IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

ISNSPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSS-------DYYRV----QSKSLLPVRWMPSESIL
 .. |.    |.  ..|....||..||.||. ....|||||||||||.|...|||||||||||||.        ||||.    ..|..||.|||. |.| 
RKHRPK----LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECIN

YGKFTTESDVWSFGVVLWEIYSYGMQPYYG-----FSNQEVINLIRSRQLLSAPEN--------CPTAVYSLMIECWHEQSVKRPTFTDISNRL
||||||.||||||||..|||..||.|||.|      ||||||......  .  |.|        ||...|..| .||||.  .||||..|  ..
YGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase Ror.AA TK 410-670 25 1.1e-122 413.32 In-house 1-486 (486) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-486/486
Sequence Identity: 25% (126 aa)

VEFLEELGEGAFG---KVYKGQLLQPN----------------------KTTITVAIKALKE--NASVKTQQD--------------FKREIELISD--L
......||||.||   .||||.. ..|                      .....||.| |||  ..| . ..|              . .|... .   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KHQNIVCILGVVLNK------------EPYCMLFEYMANGD----LHEFLISNSPTEGK-----------------------------------------
.|.||| ..||.. .            ||.... |||..||    |...| ...|.. .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

----------SLSQLEFLQ-------------------IALQISEGMQYLSAH------HYVHRDLAARNCLVNEGLV-----------VKISDFG----
          .|.. ..||                   ...||..||.||...      ..||||||||||||.|..|           .||.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LSRDIYS------------------------SDYYRVQSKSLLPVRWMPSESIL---------YGKFTTESDVWSFGVVLWEIYSYGMQPYYG-FS
    |.|||||                        .|||| ||.  ||.|||. |...         ||||||.||||||||..|||..|| .||||  |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

N---------QEVINLIRS--------------RQLLSAPENCP--------------TAVYSLMIECWHEQSVKRPTFTDISNRL
|         |||....|.              |  . .|..||              ...| || .|||..  .||||... ..|
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase Ror.AA Trk 410-670 46 1.5e-122 413.41 In-house 1-275 (275) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-275/275
Sequence Identity: 46% (128 aa)

VEFLEELGEGAFGKVYKGQ--LLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSP--
. .  ||||||||||. ..   | |..  . ||.|.||. ||..  .||.|| ||  .|.||.|| . ||  . .|  | |||| .||| ..| .  |  
IVLKWELGEGAFGKVFLAECYNLCPEQDKMMVAVKTLKD-ASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQHGPDA

---TEGKS------LSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYS-SDYYRVQSKSLLPVRWMPSESILYGKFTT
   ....       | . . | || ||  || |.   |.||||.|.||||| ..|.|||.|||.|||.|| .|||||  .  ||.|||| |||.| |||.
MCYAQYQPRQAPGPLTIDQMLWIAKQIASGMVYMASQHFVHRDMATRNCLVGQNLIVKIGDFGMSRDVYSHTDYYRVGHHTMLPIRWMPPESIMYRKFTY

ESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQL-LSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRL
||||||||||.||...|| ||.|. ||.|||. |   .. |  |. ||  || .|. ||. . ..| .  || ...
ESDVWSFGVVMWECFTYGKQPWYQLSNHEVIECIHQGRHRLERPRRCPQEVYDIMLGCWQREPQQRMNIKDIHDII
Kinase Ror.AA Musk 410-670 46 1e-116 387.29 In-house 1-282 (282) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-282/282
Sequence Identity: 46% (132 aa)

VEFLEELGEGAFGKVYKGQ--LLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSP--
...  ..|||||| |.      | |    . ||.| ||..|| . |.||.||  ..    |.|||  |||     | |.|||||| ||| ||| | ||  
IIYVRDIGEGAFGRVFQARAPGLVPYEEETMVAVKMLKDDASKQMQMDFQREACMMAEFDHPNIVKLLGVCFVGRPMCLLFEYMAYGDLNEFLHSCSPHR

-----TEGKS------------LSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESI
     .. ..            |. .. |..| ||  || |||   .|||||| ||||.||  .|||.|||||| ||. |||. .     |.|||| |||
TCSRTHQDRGMRAQVSSPGPPQLKCYHQLCMAKQIACGMAYLSEMMFVHRDLATRNCLINEHMDVKIADFGLSRYIYHQDYYKGHENDHIPIRWMPPESI

LYGKFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRL
.| .||.|||||..||.||||.||. ||||| .  |||  ||    || |||||  || || .||  .   || |..| . .
WYNQFTYESDVWAYGVCLWEIFSYALQPYYGMTHEEVIYYIRQGNILSCPENCPQKVYQLMRRCWQKNPADRPFFCQIHHCI
Kinase Ror.AA InsR 410-672 41 1.7e-106 358.78 In-house 1-278 (278) Show / Hide 
Range on Protein: 410-672
Range on HMM: 1-278/278
Sequence Identity: 41% (116 aa)

VEFLEELGEGAFGKVYKG---QLLQPNKTTI-TVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSP
.. . |.|.|.||.|| |    ... .. .   .||| ..||||..   .|  | .     .. ..|  |||.   .|     | |. |||  .| |  |
IVLIRECGQGSFGMVYEGIAKGIVPDEEWRFGRCAIKTVNENASMRERIEFLNEASVMKEFNCHHVVRLLGVCSRGQPMYVVMEMMTYGDLKSYLRSRRP

TEG------K----SLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTT
 |.      .      .  ...| | .|  || || |  .||||||.|||.||. . ||| |||. |||| .||||   |..||||||. ||.  |.|||
EEEFNNPGCNRNQHVPCLDQMHQMAAEICDGMAYLAAKKFVHRDLACRNCMVNHDFTVKIGDFGMTRDIYEHDYYRKGGKGMLPVRWMAPESLKDGVFTT

ESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLI-RSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKT
 ||||||||||||. . | ||| | || .| . | . . .|  ||||| ... ||  ||. |.  ||||.|| . |. 
HSDVWSFGVVLWEMVTLGEQPYQGLSNEQVLKYIGMDGNVLRPPENCPEYWQELMMMCWQYQPKMRPTFLDIIHYLCD
Kinase Ror.AA UTK 410-670 35 6.30000000001e-102 344.93 In-house 1-296 (296) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-296/296
Sequence Identity: 35% (106 aa)

VEFLEELGEGAFGKVYKGQLLQPN--KTTITVAIKALKENASVKTQQD----FKREIE---LISDLK-HQNIVCILGVVLNKEPYCMLFEYMANGDLHEF
|.....||.|||| |.|. . |..   ..  ||.|.... |.  ....    | .|     . . .. |.|..  .||... || ... |||.||||  .
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSY

LISNSPT---EGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEG-------LVVKISDFG---LSRDIY---------SSDYYRVQSKSL
| ...||   .. .|.  . |. |..|..|||||. ...||||||||||||..        .|.||.|||   .||...         .|.||. |.   
LRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDR

LPVRWMPSESILYG-KFTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSR--QLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRL
.|.|||  |.. .. .||| |||||||||.|||...| .|| | ||..|.  .. .  ... .|. || .|| || .|||    .||.| |.  ..
WPIRWMAPEALTHHTRFTTKSDVWSFGVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase Ror.AA TK-Unique 410-670 35 7.1e-102 344.75 In-house 1-294 (294) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-294/294
Sequence Identity: 35% (105 aa)

VEFLEELGEGAFGKVYKGQLLQPN---KTTITVAIKALKENASVKTQQDFKREIELISDLK-HQNIVCILGVVLNK-EPYCMLFEYMANGDLHEFLISNS
.|.....|||||| |..|.. ...     .. ||.|.||.||.  ..|||..||.. . |. |.||| .||.   . || ....||...|.|  .| .. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

P------------------TEGKS---LSQLEFLQIALQISEGMQYLSA--HHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQ-SKSLLPV
|                  .....   .|   ....| ||  ||.||.   .. |||||.|||.|..|..|.||.|||..||.|    |  . |.. .|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPI

RWMPSESIL--YGKF-TTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENC-PTAVYSLMIECWHEQSVKRPTFTDISNRL
|||. ||..  .| . ||.||||||||..||| ..| .||.| .. .....||    .  ||.| . ..|.||..||..   .||.|..| .||
RWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFTLGACPYPGMPWKDIMECIRDGYRMPQPEHCCSHEMYNLMKSCWQWEPEERPSFRQIKHRL
Kinase Ror.AA ALK 410-672 39 2.2e-93 316.57 In-house 1-273 (273) Show / Hide 
Range on Protein: 410-672
Range on HMM: 1-273/273
Sequence Identity: 39% (108 aa)

VEFLEELGEGAFGKVYKGQLLQ--PNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTE
.. .  || |||| || ||          . ||.| |.| .| . . ||  |   ..  .|||.|  .|. . | ||  . |||. ||.  ||  . |..
ITLVRALGHGAFGEVYMGQYSHMPGDSVPMQVAMKTLPEDCSQQDEEDFCMEALIMGKFNHQNVVRCIGICFQKQPYMIVLEYMEGGDMKSFLRECRPHP

G----KSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLV---NEGLVVKISDFGLSRDI-YSSDYYRVQSKSLLPVRWMPSESILYGKFTTESDV
.     .|     ||... .  | .||   |..||| ||||||      | |.|| ||| .||| | .||||   . ..|| ||| |  . | ||. .||
ESLQPSQLTMKDLLQCCCDVAQGCHYLEENHFIHRDIAARNCLLTCKGPGRVAKIADFGMARDITYRADYYRKGGRAMMPVKWMPPEAFMDGIFTSKTDV

WSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRLKT
||||| .|||.| |. || | .||||. .. .   .  | |||. || .| .||  |   ||.|..|  ... 
WSFGVLCWEIFSLGYMPYPGRHNQEVMEFVTEGGRMDPPRNCPQPVYRIMTQCWQHQPEDRPKFVTILEHIQY
Kinase Ror.AA Src 410-670 36 6.3e-89 301.73 In-house 1-255 (255) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-255/255
Sequence Identity: 36% (97 aa)

VEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGK
. ....||.| || |..|      . .. ||.| ||.      ...| .|...   |.|...| .. |.  .||.    |||..| | ..|     .||.
IKLCRKLGQGQFGEVWMGYW----NGNTKVAVKTLKPGT--MSPEAFLQEAQIMKKLRHEKLVQLYAVCSQEEPIYIVTEYMSHGSLLDYLKK--DGEGR

SLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYS--SDYYRVQSKSLLPVRWMPSESILYGKFTTESDVWSFGVVLW
.|.  . . .| |..|||.||..  |.|||||||| ||.|..|.|. |||| | .     | |  .. . .|..|.  | |.||.||. |||||||. |.
HLHLPQLIDMAAQVAEGMAYLESMNYIHRDLAARNVLVGENNVCKVADFGLAR-LIKEDDDEYCARHGAKFPIKWTAPEAINYGRFTIKSDVWSFGILLT

EIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYS-LMIECWHEQSVKRPTFTDISNRL
|| .||  || | .|.||.  .     .  |.|||  .|  .| .|||..  .||||  . . |
EIVTYGRVPYPGMTNHEVLQQVERGYRMPCPHNCPDELYEQIMLQCWHKDPEQRPTFEYLQWFL
Kinase Ror.AA Eph 410-670 40 4.1e-87 292.66 In-house 1-264 (264) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-264/264
Sequence Identity: 40% (108 aa)

VEFLEELGEGAFGKVYKGQLLQP-NKTTI---TVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSP
.   . .|.| || |..| |  |  |. .   .||||.||. .. | . || .|  ..    | ||.   |||   .|   . |||.|| | .||  .  
IKIEKVIGAGEFGEVCCGRLKLPSGKREVWVDPVAIKTLKAGYTEKQRWDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEYMENGSLDSFLRQH--

TEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSD----YYRVQSKSLLPVRWMPSESILYGKFTTESDVWS
 .|  .. .  . .   |  ||.||| . |||||||||| |||. || |.||||||| . . .     |  .  .  |.||   | | |.|||. |||||
-DG-QFTVIQLVGMLRGIASGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPSVEATYTTR-GGKIPIRWTAPEAIAYRKFTSASDVWS

FGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISNRL
.|.|.||. |||  ||   |||.||. |     | .| .||.| . || .||. .  .||.|..| . |
YGIVMWEVMSYGERPYWDMSNQDVIKAIEQGYRLPPPMDCPEALHQLMLDCWQKDRNHRPHFQQIVSIL
Kinase Ror.AA S_TKc 410-674 24 2.2e-49 171.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 410-674
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

VEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALKENASVKTQQDFKREIELISDLKHQNIVCILGVVLNKEPYCMLFEYMAN--GDLHEFLISNSP-T
 |.|...|.||||||||..      |   |||| .|        ....|||.. .  .| ||| ...|  . . ..| .||. .  |||.... .. .  
YEILRKIGKGAFGKVYKCRHKK---TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

EGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSLLPVRWMPSESILYGKFTT-ESDVWSFGVV
 .. ..  .   .. || ....|.  |. .||||   | |..|  ..||.||||.| .         .       .|. | .   .... ..|.||.|..
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFTDISN-----RLKTWH
|.| .. |  |..    |.....|.           .  . ...  |..    ||||  .. .     ..  | 
LYEMLC-GYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase Ror.AA Pkinase 410-670 23 1.1e-41 148.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 410-670
Range on HMM: 1-293/293
Sequence Identity: 23% (71 aa)

VEFLEELGEGAFGKVYKGQLLQPNKTTITVAIKALK--ENASVKTQQDFK-REIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANG----DLHEFLIS
 .... .|.|.||.|||..    .|   .||.| .|  .. | | |.... .||..   |.| ||| ..... .|  ..| .||. .|    ||....  
YHIGRKIGSGSFGCVYKCHHKGTGK---IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

NSPTEGKSL--SQLEFLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVV----KISDFGLSRDIYSSDYYRVQSKSLLPV---RWMPSESIL-YGK
    .....  |  |   ...|| .|..|. ..  .||||   |.|...  ..    ||.||||.. ..    |  .|    ..   ..|. | |. . .
---WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----Y-NNS-MTTFCGTPWYMAPEVIRGGQY

FTTESDVWSFGVVLWEIYSYGMQPYYGF------SNQEVINLIRSRQLLSAPE--------------------NCPTAVYSLMIECWHEQSVKRPTFTDI
 ....|.||.|..|.| .. |  |..|       . ...|..|....| .  .                    | . .  ...  |..    ||||...|
YGPKVDMWSCGCILYEMLC-GRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQI

SNR--L
 .   .
LQHPWF