Gene Pk17E (Fruit Fly)
Pk17E
Sequence
Protein domains of Pk17E.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | Pk17E.AA | RSKR | 159-436 | 58 | 6.4e-219 | 733.56 | In-house | 1-296 (296) | Show / Hide |
Range on Protein: 159-436 Range on HMM: 1-296/296 Sequence Identity: 58% (172 aa) YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCG--------------HHPFIVKQIDLWQNRHNLHILSEYVP-N ||||||||||.||||..||...|..||.|.|..||.|.|..|.|||.||||.||..|. |||||..|.|.|||||.|....||.| . YRIDHLVAKGSFGVVYCVSDCHDQKQCFAIKMQKKRKIIQRNTVRQCKDEASIQRCCQDVTSDHSHFQRLLPHHPFIHRQYDTWQNRHHLYMMCEYPPCH GELFSKIT---HFSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKYMAPEILCGEPYGHAVDWWA |.|.|... |||....||.|.|.|.||..||||||||||.|.|||||....||||||||||||.|.||.|.|.|||..||||||||||||.||||||. GDLYSLWRQRGHFSEMAIRLFIAELAMALCYLHNAGIIYRDVKMENILLDQWGHIKLTDFGLSKWMKQGARTYTICGTLQYMAPEILCGEPYNHAVDWWS LGVIACQMLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEEVQHLTHEGRDVLRKLLTIEPRQRIRSVMALQRIAIY ||||.|||||.|.||||||||||||.....|......|.|.|..||.||||||||||||||||..||..|.....|...|..|..|...||.... LGVIMCQMLTGKYPNIKRHLLRRREYDNERDHFTMHASVAHIDYCLPDSDGDSEDFLPEEVQHCSHEFCDLMHRMLCQNPNHRLCSLHHLQHHPFF |
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Kinase | Pk17E.AA | AGC | 159-354 | 29 | 3.1e-108 | 280.41 | In-house | 1-304 (395) | Show / Hide |
Range on Protein: 159-354 Range on HMM: 1-304/395 Sequence Identity: 29% (92 aa) YRIDHLVAKGAFGVVFKVSSKS-----DISQCYALKVLKKSK-LIEDN--SVRQIKDE------------ADIQKVCGH---------HPFIVK-QIDLW ... .. ||.|| |. | |. | . ||.|||||.. .... |.... | .| . | | |||||| . FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QNRHN--LHILSEYVP---------NG-ELFSKIT------HFSIDLVRLYIGE-------IALALDFLHN-AGIIYRD-AKPENILLTEQFHIKLTDFG |. . |... ||.| | |||. . .|. . .| |. | |.|||..||. |||.|| |||||||.|. |||||||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG LSKWLKLG---------------------------------------------------ANTRTMCG--TFKYMAPEILCGEPYGHAVDWWA--LGVIAC |.|... . . | |.|| | ||||||| ||.|.|||. ||.. . LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY QMLTQKSP .||| ..| EMLTGYPP |
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Kinase | Pk17E.AA | S_TKc | 159-435 | 30 | 6.7e-75 | 256.05 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 159-435 Range on HMM: 1-231/231 Sequence Identity: 30% (90 aa) YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIVKQIDLWQNRHNLHILSEYVPN--GELFSKITH---- |.| .. |||||.|.|. |. . .|.|..| ..|. | .| | |||.||| .| .|. ..|.. ||... |.||. | . YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH -----FSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKYMAPEILCGEPYGH-AVDWWALGVIAC |. .| |. .|..||...|. |||.|| |||||||.| |||..||||.. | .|.||| |||||.| .||. ..|||..|.| GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY QMLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEEVQHLTHEGRDVLRKLLTIEPRQRIRSVMALQ-------RIAI ||. . | .. . . . ..|..| .||.|. .|..|. ||| . EMLCGYPPFP--QMQMMFKKIG------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | Pk17E.AA | Pkinase | 159-354 | 33 | 4.7e-59 | 207.3 | Pfam | 1-211 (293) | Show / Hide |
Range on Protein: 159-354 Range on HMM: 1-211/293 Sequence Identity: 33% (71 aa) YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIK-DEADIQKVCGHHPFIVKQIDLWQNRHNLHILSEYVPNG----ELFSKIT-- |.| . .|.||.|.| |.. .. .|.|..||.. .. .. .. |. | | . .||.||. .| .... .... ||...| .||. |. YHIGRKIGSGSFGCVYKCHHKGT-GKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW ---HF--SIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHI----KLTDFGLSKW--LKLGANTRTMCGTFKYMAPEILC-GEPYGHAVDWW | | . .. |. .|. .|...|. |||.|| ||||||. .. || |..||||.| . . . | ||| |||||.. |..||..||.| RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW ALGVIACQMLTQKSP ..|.| .||. . | SCGCILYEMLCGRPP |
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Kinase | Pk17E.AA | RSK | 163-350 | 40 | 6.4e-59 | 202.07 | In-house | 1-207 (278) | Show / Hide |
Range on Protein: 163-350 Range on HMM: 1-207/278 Sequence Identity: 40% (83 aa) HLVA-KGAFGVVFKVSSK--SDISQCYALKVLKKSKLIEDNS-VRQIKDEADIQKVCGHHPFIVKQIDLWQNRHNLHILSEYVPNGELFSKIT---H--- . |. .|..| || . . .| | || |||||.|.. . .| . | .| . |..|||||. . | |.. ||.. |||| .. | LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC FSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTE---QFHIKLTDFGLSKWLKLG--ANTRTMCGTFKYMAPEILC---GEP-YGHAVDWWALGV || | .. |. ||.||...|| |||.|| ||||||... . ||||||||..| ... | | |.| |||||.| .. ...|.||| ||| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV IACQMLT . ||| LMYEMLT |
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Kinase | Pk17E.AA | SGK | 159-342 | 38 | 7e-57 | 173.97 | In-house | 1-212 (283) | Show / Hide |
Range on Protein: 159-342 Range on HMM: 1-212/283 Sequence Identity: 38% (81 aa) YRIDHLVAKGAFGVVFKVSSKSD-----------------ISQCYALKVLKKSKLI-------EDNSVRQIKDEA-DIQKVCGHHPFIVKQIDLWQNRHN .. ... || || |. | |.| . ||.|||.| | .... |. | .| | . |||||. |. FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILK-NMKHPFIVNLHYAFQTKWK LHILSEYVPNGELFS---KITHFSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSK-WLKLGANTRTMCGTFKYMAPEILCG | .|| ||.|. . ||. | .| | ||..||. || ||||| ||||||| | |..||||||.| | | | ||| |.|||.| . LYFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK EPYGHAVDWWALG .|.. .|||| || QPHDRTVDWWCLG |
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Kinase | Pk17E.AA | PKA | 159-344 | 40 | 1.6e-55 | 190.77 | In-house | 1-188 (263) | Show / Hide |
Range on Protein: 159-344 Range on HMM: 1-188/263 Sequence Identity: 40% (78 aa) YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIV-KQIDLWQNRHNLHILSEYVPNGELFS---KITHFS . | .. .| || | . .|.. . ||.|.|||.. . . | ...| | . . .||||| | .. .|.. .|. . |||| ||.|| | .|| FEIIQTLGTGSFGRVMLCRHKHSG-NYYAMKMLKKQEIVRLKQVEHVHNEKNILQNI-KHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFS IDLVRLYIG-EIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKYMAPEILCGE-PYGHAVDWWALGVI . ..|. .| |||..||. ||||| ||||||. .. |||.|||| .| .. .| |.|||. |.||||. .. ..| .|||||||.. NPHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGIL |
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Kinase | Pk17E.AA | CAMK | 164-344 | 20 | 1.1e-54 | 174.26 | In-house | 1-323 (425) | Show / Hide |
Range on Protein: 164-344 Range on HMM: 1-323/425 Sequence Identity: 20% (66 aa) LVAKGAFGVVFKVSSKSDIS-----------QCYALKVLKKSKLIE-------------------------DNSVRQIKDEADIQKVCG------HHPFI .|.||.|... |.. | .| |...|.|| . ... .... | .| | . .|| | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI VKQIDLWQNRHN-------------------LHILS---EYVPNGEL----FSKI------------------THFSIDLVRLYIGEIALALDFLHNAGI .| .. ....|. ... ||...||| |..| .|. . .| |. |. |....|. .| IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI IYRDAKPENILLTEQ-----------------FHIKLTDFGLSKWLKL------------------------GANTRTMCGTFKYMA-PEILCG------ . || |||||||.. . ||..|||... .. | .|.||| ||| ||.| | VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM --------EPYGHAVDWWALGVI ..|| ..| |..||| QNATDEEKPYYGPKCDMWSCGVI |
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Kinase | Pk17E.AA | AktR | 159-343 | 42 | 2.6e-54 | 186.75 | In-house | 1-193 (268) | Show / Hide |
Range on Protein: 159-343 Range on HMM: 1-193/268 Sequence Identity: 42% (82 aa) YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIVKQIDLWQNRHNLHILSEYVPNGELFSKIT---HFSI ... . ||||| |. | | | . ||.|..||.|.|| | ... | .| . | |||||| . .|.. .| ...||.|.||||. . .|| FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE DLVRLYIGEIALALDFLHNA-GIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGAN---TRTMCGTFKYMAPEILCG-EPYGHAVDWWALGV . .| |. .| |||..||. ||||| ||||||| | |.|.||||||| .. .. ... |||..|||||.. .... .|||||.|. EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGI |
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Kinase | Pk17E.AA | MSK | 161-354 | 32 | 1.2e-53 | 179.7 | In-house | 1-209 (277) | Show / Hide |
Range on Protein: 161-354 Range on HMM: 1-209/277 Sequence Identity: 32% (68 aa) IDHL--VAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQI-KDEADIQKVCGHHPFIVKQIDLWQNRHNLHILSEYVPNGELFSKIT---HFS . | ..|.|... |.. ... . || |.|.| .. . . |. . . | ||.||. . | ... ||. |||| .| ||. LKVLGTGGYGKFFICRKCVHHDT-GKLYAMKILSKATVVQKRKTAEHTQTERQCLEMCQQHPNIVNLHYAFQDQCHTYLVMEYCNGGELFTHIRKREHFD IDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQ---FHIKLTDFGLSKWLKLG--ANTRTMCGTFKYMAPEILC----GEP-YGHAVDWWALGVI . .| ...|. .|.|..| |||.|| ||||||.... |.||.|||... . . . . |.| |||||.| ... |. |.||| |||| ESECRMIMRELVMAVDHMHQKGIIHRDLKPENILFDDEEDNGHVKLIDFGFARLFPQDEEWRMKSPCFTLHYMAPEMLRRGYAQDGGYDEACDWWSLGVI ACQMLTQKSP ||| ..| LYTMLTGQVP |
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Kinase | Pk17E.AA | Ciliate-E2 | 159-435 | 21 | 6.4e-52 | 176.5 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 159-435 Range on HMM: 1-365/365 Sequence Identity: 21% (86 aa) YRIDHLVAKGAFGVVFKVSSKSD----------------------ISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGH------------HPFIVKQ | . . .|.||.|.|.. ... .. ||.|..||..... ... .| | .. . ||.|.| YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FY--KKINEKNILEQLNHPNIIKM IDLWQ--NRHNLHILSEYVPNGELFSKIT--------------HFSIDLVRLYIGEIAL---------------ALDFLHNAG-IIYRDAKPENILLTEQ .. .| ...|. . ||. |.||. | |.. .. .. .|. || .||. . ||.|| ||||||. YECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--- FHIKLTDFGLSK----------------WLKLGAN-----------------TRTMCGTFKYMAPEILCGEP---------YGHAVDWWALGVIACQMLT ||..|||||| |.. | ..| ||| ||||||| |.. |....|.|.|||| .||. --IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF QKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEE--------------VQHLTHEGRDVLRK----LLTIEPRQRIR-SVMALQ | | .| || ..| .... |. | ..| .| .| .|| .|. GKPPF------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILN RIAI . HPWF |
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Kinase | Pk17E.AA | p70 | 218-350 | 44 | 1.1e-43 | 151.51 | In-house | 87-233 (299) | Show / Hide |
Range on Protein: 218-350 Range on HMM: 87-233/299 Sequence Identity: 44% (66 aa) HPFIVKQIDLWQNRHNLHILSEYVPNGELFSKITHFSI---DLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKW-LKLGAN-- ||||.. . | | . || . |||| .| | .. | || .|| .|| |||||| ||||..| .| |..||||||.| .. || HPFICDLHYAFQTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDE --------TRTMCGTFKYMAPEILCGEPYGHAVDWWALGVIACQMLT | |.||| ||||||| . ..||||||.||. ||| EDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLT |
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Kinase | Pk17E.AA | TyrKc | 159-433 | 18 | 2.2e-11 | -38.63 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 159-433 Range on HMM: 1-280/280 Sequence Identity: 18% (59 aa) YRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCG-HHPFIVKQIDLWQNR-------HNLHILSEYVPNGELFSKI . .. ||||.|.| | . | |.||... .. . .|| | . | ||| ||. . . | |. ||.|.| | . . ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL --TH--FSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLG-------ANTRT----MC---GTFKYMAPEILCGEPY .. .. . . || ..|| ..| || |.|..|....| .|||||. .. . |. . . |||| . . RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF GHAVDWWALGVIA------CQMLTQ------KSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEEVQHLTHEGRDVLRKLLTIEP .. | |. || .|. .|. ........ .. . | .. | . . | .. .. .| TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS---------------F-----VCCPDEMYQIMKQCWHEDP RQRIRSVMALQRI .| . ... EDRPTFSEIHECF |
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Kinase | Pk17E.AA | p70 | 159-197 | 34 | 0.000201 | 12.11 | In-house | 1-41 (299) | Show / Hide |
Range on Protein: 159-197 Range on HMM: 1-41/299 Sequence Identity: 34% (14 aa) YRIDHLVAKGAFGVVFKVSSKS--DISQCYALKVLKKSKLI . .. ||..| || | | .. || |||.| | . FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIV |
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Kinase | Pk17E.AA | AGC | 398-426 | 27 | 0.00031 | 5.27 | In-house | 348-376 (395) | Show / Hide |
Range on Protein: 398-426 Range on HMM: 348-376/395 Sequence Identity: 27% (8 aa) PEEVQHLTHEGRDVLRKLLTIEPRQRIRS ..|..... | .| ..|||. .|..|. . FPEDRWFSPEAKDLIKKLLCKDPEKRLGC |
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Kinase | Pk17E.AA | Pkinase_Tyr | 286-304 | 47 | 0.000863 | 13.46 | Pfam | 141-159 (270) | Show / Hide |
Range on Protein: 286-304 Range on HMM: 141-159/270 Sequence Identity: 47% (9 aa) NILLTEQFHIKLTDFGLSK |.|.||....| .||||.. NCLVTENNVVKICDFGLAR |
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Kinase | Pk17E.AA | p70 | 404-424 | 57 | 0.017619 | 4.99 | In-house | 263-283 (299) | Show / Hide |
Range on Protein: 404-424 Range on HMM: 263-283/299 Sequence Identity: 57% (12 aa) LTHEGRDVLRKLLTIEPRQRI ||||.|| ..||| .| ||. LTHEMRDLIKKLLKRHPTQRW |
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Kinase | Pk17E.AA | CAMK | 395-431 | 19 | 0.026336 | 2.43 | In-house | 365-421 (425) | Show / Hide |
Range on Protein: 395-431 Range on HMM: 365-421/425 Sequence Identity: 19% (11 aa) DFLPEEVQH--------------------LTHEGRDVLRKLLTIEPRQRIRSVMALQ || |... . .. | .| .||.|. .| .|. .|. DFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLN |
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Kinase | Pk17E.AA | RSK | 402-424 | 39 | 0.029467 | 4.5 | In-house | 240-262 (278) | Show / Hide |
Range on Protein: 402-424 Range on HMM: 240-262/278 Sequence Identity: 39% (9 aa) QHLTHEGRDVLRKLLTIEPRQRI | |..| .| .||.|. .| .|. QYLSQEAKDLIRKMLHRDPHKRL |
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Kinase | Pk17E.AA | Pkinase_Tyr | 159-175 | 35 | 6.457225 | 0.34 | Pfam | 1-17 (270) | Show / Hide |
Range on Protein: 159-175 Range on HMM: 1-17/270 Sequence Identity: 35% (6 aa) YRIDHLVAKGAFGVVFK .... .||||.|.| ITFGKKLGEGAFGEVYK |