Gene CG1973 (Fruit Fly)
CG1973
Sequence
Protein domains of CG1973.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | CG1973.AA | SCY1 | 30-263 | 27 | 1.2e-103 | 350.66 | In-house | 1-337 (337) | Show / Hide |
Range on Protein: 30-263 Range on HMM: 1-337/337 Sequence Identity: 27% (93 aa) WTLHKAKRKTTLEEVSVFVYDIR--------SGSDTKCELAKAALKRLKTLRHPSILQYLDSLETDKM--LYVATEAVDPLGTYFSKLGSDNV------- |..|....|.| .|.||||.|.. |.....||..|.. ||||.||||.||||...||..|. .|...|...||.....|...... WKIHNGTKKYTGQECSVFVFDKKNIEKWHKDSWWEEICEFLKKQAKRLKRLRHPNILQYIHPLEESKDCMMYATEEIFQPLENVLKKWDNKKSCQTQKTQ --------------------QKGLYLAWGIFQITRALSFLNNDGNLRHNNVSAWSVFVNASGEWKLGS---------LEYVSAAD-GNP-MPPAKIPVT- .. |.. ||||||..|||||.||....|||....|.|||..|.||.| ...|.... ||| ||. . ... DVDFGQNTQPQRPYHKKDWKLDELEVCWGIFQILDALSFLHNDCHMVHNNICPESIFVNKNGDWKIGGDDDDAGGWGMDFVCDIQNGNPQMPWFPCQEWR ------------LEVYDSPEKNDPSKLKAATK-------------------CSVDMWGLGCLVWEAFNGVLKQRSNLKDI-------------------E .. |..|....|. |. .. .. ||..||||.|. .||. .|....... . EMDYISVSSTKPDNKYPPPCQPNPDWLAPEYIHEDQHTPASYNWGQEQKCTWASDMFSLGCLIWWVYNGKKPQITCNSNPYSTFHRYMEQWNAMSHCWWD HIPKSLQSL----YCELVGASPSNRPNPADIITRCRK ||||.||.. ||.|....| .||.|......|.. HIPKELQEHLGHCYCHLLHQDPTCRPDPQQFLQHCYF |
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S_TKc | CG1973.AA | S_TKc | 15-294 | 14 | 1.1e-05 | -93.61 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 15-294 Range on HMM: 1-231/231 Sequence Identity: 14% (44 aa) YDIGEPVGGFDQYSIWTLHKAKRKTTLEEVSVFVYDIRSGSDTKCELAKAALKRLKTLRHPSILQYLDSLETDKMLYVATEAVDP-LGTYFSKLGSDNVQ |.|....| . . . .|.. | | ..| . . . | .. .. || .|| | ...|. .. . ||. .| .| ||. |. . . . . YEILRKIG---KGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH -----KGLYLAWGIF-QITRALSFLNNDGNLRHNNVSAWSVFVNASGEWKLGSLEYVSAADGNPMPPAKIPVTL-----EVYDSPEKNDPSKLKAATKCS |. .. || .|| .. . . | . .... . |.. . .|. || .||. GLRFPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL------------GYGKCK VDMWGLGCLVWEAFNGVLKQRSNLKDIEHIPKSLQSLYCELVGASPSNRPNPADIITRCRKPGGFFKNDLVDTLLFLEEIQIKD-------KAEK----- .|.| .||...| . | . ... . .. . . . |.. . || .| . CDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDI --NRFF .| KCHPWF |
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Kinase | CG1973.AA | Fused | 70-95 | 42 | 0.000213 | 10.78 | In-house | 53-78 (251) | Show / Hide |
Range on Protein: 70-95 Range on HMM: 53-78/251 Sequence Identity: 42% (11 aa) KTLRHPSILQYLDSLETDKMLYVATE . ..|| | .|| |||| . | |. RRMHHPHIIHMIDSFETDKEVVVVTD |
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Kinase | CG1973.AA | ARK | 233-260 | 28 | 0.000582 | 10.63 | In-house | 253-280 (280) | Show / Hide |
Range on Protein: 233-260 Range on HMM: 253-280/280 Sequence Identity: 28% (8 aa) PKSLQSLYCELVGASPSNRPNPADIITR | .| .|. .. .|.|||. .|.. PEQLKNLIQCCWDQDPDNRPSCEEIMEE |
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Kinase | CG1973.AA | QIK | 69-95 | 44 | 0.000763 | 11.24 | In-house | 52-78 (272) | Show / Hide |
Range on Protein: 69-95 Range on HMM: 52-78/272 Sequence Identity: 44% (12 aa) LKTLRHPSILQYLDSLETDKMLYVATE .| |.|| | .. .|||.|.|. || MKMLYHPHIIKLYQVMETDDMMYIVTE |
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Kinase | CG1973.AA | Ciliate-E6 | 66-83 | 50 | 0.000817 | 8.43 | In-house | 1-18 (154) | Show / Hide |
Range on Protein: 66-83 Range on HMM: 1-18/154 Sequence Identity: 50% (9 aa) LKRLKTLRHPSILQYLDS ..|| .||.||.|.|| IQNLKNCNHPNILKYMDS |
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Kinase | CG1973.AA | Fused | 204-218 | 53 | 0.090969 | 1.61 | In-house | 179-193 (251) | Show / Hide |
Range on Protein: 204-218 Range on HMM: 179-193/251 Sequence Identity: 53% (8 aa) DMWGLGCLVWEAFNG ||| ||| ..| . | DMWSLGCILYELMVG |
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HEAT | CG1973.AA | HEAT | 350-380 | 22 | 0.862195 | 6.6 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 350-380 Range on HMM: 1-31/31 Sequence Identity: 22% (7 aa) IVPCVVKLFASTDRVTRSRLLQQLDLFIAHL |.|...|.. ..| |. .. | .. |. ILPHLLKCLNDPDWEVREAACWCLGQLCEHC |
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HEAT | CG1973.AA | HEAT | 389-419 | 19 | 0.000827 | 17.05 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 389-419 Range on HMM: 1-31/31 Sequence Identity: 19% (6 aa) IFPQVAHGFLDTNATIREQTVKSIIHLAPKL |.| . ... |... .||...... .|.... ILPHLLKCLNDPDWEVREAACWCLGQLCEHC |
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HEAT | CG1973.AA | HEAT | 428-459 | 25 | 6.089122 | 3.66 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 428-459 Range on HMM: 1-31/31 Sequence Identity: 25% (8 aa) VLRHFARLQARDDQGGIRTNTTVCLGKIAPHL .| |. .. |. .| .. |||....|. ILPHLLKCLN-DPDWEVREAACWCLGQLCEHC |
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HEAT | CG1973.AA | HEAT | 468-498 | 16 | 0.267513 | 8.36 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 468-498 Range on HMM: 1-31/31 Sequence Identity: 16% (5 aa) LVSAFIRAMRDPFPPARVAGVLALAATQQYF ..........|| . | | . .|.. ... ILPHLLKCLNDPDWEVREAACWCLGQLCEHC |
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HEAT | CG1973.AA | HEAT | 507-537 | 25 | 0.009498 | 13.38 | Pfam | 1-31 (31) | Show / Hide |
Range on Protein: 507-537 Range on HMM: 1-31/31 Sequence Identity: 25% (8 aa) VLPSLCSLTVDPEKTVRDPAFKTIRGFLGKL .|| |... ||. ||. |.... .. .. ILPHLLKCLNDPDWEVREAACWCLGQLCEHC |