Gene Slob (Fruit Fly)
Slob
Sequence
Protein domains of Slob.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
---|---|---|---|---|---|---|---|---|---|
Kinase | Slob.AA | Slob | 181-399 | 41 | 1.2e-136 | 460.26 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 181-399 Range on HMM: 1-268/268 Sequence Identity: 41% (113 aa) LDEIGSRHGKNWFLVT-DASVRTDRLQTLLPLPPDCVAFEDLPPNECAREILMELLGSLHHPYIYPVLDLGFLRNSSYNYACLVTPFNSRGSLKDLIYKA ||.||.||.|||.... |........|......|||.....|...||. ..|..|.|.||||||||..|.|..|...||.|....||.||||||.|||| LDHIGWRHRKNWCMMKNDMQPGEECVQSWIDYGPDCCPWKMLNEKECQ--CFMKILMSCHHPYIYPVINLVFFINHKHNYCCVIRFFNKRGSLKDFIYKA QWNEPWARKY------------------TRKPNGLPVSQVQRLGRQILEALLFLKERGFPLHGHLHSGNVILQN--GAARLSGLENGLLGLSSRIN-AVM ....|||||| ..|.||||..|||...|||||||.||...||| .||||||||.... ...|||..||.|||.....| ..| KPKMPWARKYCNKQPKSSSSSSSSSSSSHKKQNGLPMKQVQKYCRQILEALIFLHSKGFP-YGHLHSGNVMIDDSNDCCRLSDIENCLLGMPPFYNDYIM WSRSVTEIENVDIVCFGHLLYEMCTGQELTTP-----------------------------KPSMR-VLEM |.|...||||||..||||.|||||.|...... .|.|| .|.| WHRKIHEIENVDVYCFGHCLYEMCCGYPMQNHSVRNFPPCPFIALFCDKEHILSCEICKHCMPTMRQLLQM |
|||||||||
S_TKc | Slob.AA | S_TKc | 178-454 | 14 | 0.000264 | -113.78 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 178-454 Range on HMM: 1-231/231 Sequence Identity: 14% (44 aa) IAHLDEIGSRHGKNWFLVTDAS---------VRTDRLQTLLPLPPDCVAFEDLPPNECAREILMELLGSLHHPYIYPVLDLGFLRNSSYNYACLVTPFNS |..||. ..... . .. . ||| . |||.| .| .. ..|. . . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------------EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCD R--GSLKDLIYKAQWNEPWARKYTRKPNGLPVSQVQRLGRQILEALLFLKERGFPLHGHLHSGNVILQNGAARLSGLENGLLGLSSRINAVMWSRSVTEI |.|.|.| | |.. ... ..| ..... .||..|| .. ..|. .| | |. | . .. ||. .. . .| GDLGDLFDYIKK--------RGRHGLRFPFPE-HARFYMYQICCALEYCHSHGI-IHRDLKPENILLDE-HIKICD-----FGLARQL----TTFCGTPW ----------E-NVDIVCFGHLLYEMCTGQELTTPKPSMRVLEMELQHYPQIGQTRKQILEILGLIFEPPSGVCPSVEDLVLCDLFRS-----IDLRELR .|. .| .||||..|. . . .......| |.. | .. ... . |. YMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP--------------------QMQMMFKKIG---------SPEAKD-FIRKCLQKDPEKRPTA-EAL G--------PCF | | QDEWDIKCHPWF |