Gene BABO (Fruit Fly)
BABO
Species: Fruit Fly
Alias: G protein-coupled receptor kinas, Gprk3, l(2)k16912, G protein-coupled receptor kinase 3, ATR-I, CG8224, ATR-1, Activin A receptor 45A, Atr-1, BABO, AtrI, Atr-I, Atr45A, Atr45A: Activin A receptor 45A, l(2)44Fd, SFO009, STK-E, atr-I, Gprk-3, Atf1
Annotation:
Drosophila polytene location: 44F12--45A1
Sequence
Protein domains of BABO.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Activin_recp | BABO.AA | Activin_recp | 127-208 | 23 | 8.2e-32 | 107.34 | Pfam | 1-121 (121) | Show / Hide |
Range on Protein: 127-208 Range on HMM: 1-121/121 Sequence Identity: 23% (28 aa) IKCH-CDT--------CK--ESN-----NICET----------DGFCFTSVEKNSDG--SIIFSY----SCMVVKYNMQRSKPFECLT-----SNERFDT .||. |.. |. |.| ..||| ||.|..|.|.|.|. ..... .|. . .|.....||.|.. |...... LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG YRIDC-CK-SDFCNKNEIMKR ....| |. .|.||.|. . HNHECWCCETDYCNRNLTPPP |
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Kinase | BABO.AA | Type1 | 303-590 | 69 | 3.2e-273 | 749.79 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 303-590 Range on HMM: 1-290/290 Sequence Identity: 69% (202 aa) VQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLN .|....|||||.||||||.|||||||||||.||.|.|||||.|||||||.||||||||||||.||||.||||||.|||||.|||.|||..| .||..||. IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQMLR MSLSIATGLAHLHMDIVGTR--GKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFDSYKRADVY . .|.|.|||||||.|.||. |||||||||.|||||.||.|..|.|.|||||||| ...|..||....|||||||||||||||.|| ..|.|||.||.| LAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMADIY AFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALRIKKTL .|||..|||||||..|.|...|||||||.|. |||.|.|.||||..|.||||||||........|||.||||||.|| ||.||||||||| SFGLVMWEIARRCEVGGIVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRIKKTL |
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Kinase | BABO.AA | STKR | 303-590 | 57 | 3.1e-217 | 708.24 | In-house | 1-312 (312) | Show / Hide |
Range on Protein: 303-590 Range on HMM: 1-312/312 Sequence Identity: 57% (180 aa) VQLCHVIGKGRFGEVWRGRWRG----ENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDN-GTWTQLWLVTDYHENGSLFDYLTTHPVDT .||...|||||.||||.|.||| |.||||||.||.|.|||||.|||||.|.||||||.|||||.|.. |.|||.||.|.|||||||.|||. | .|. IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW NTMLNMSLSIATGLAHLHMDIV--GTR--GKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIP-------STHRVGTKRYMAPEVLDESM ..|..| .|.|.|||||||.|. || .||||||||.||||||||....|.|.|.|||.|| .. ...||. . ..|||||||||||||..| HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM NDQHFDS-YKRADVYAFGLILWEIARRCNMGM------IYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWH-ASDVLHNMAKVMKECWYPNPV | |.|.| .||.|.||.||..|||||||..|. |..|||.|.||.|. .||.|.|.||||....||||||||. ...... |.|.|.|||...| NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE ARLTALRIKKTL ||||||..|||. ARLTALCVKKTM |
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Kinase | BABO.AA | TKL | 309-590 | 31 | 1.7e-112 | 380.07 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 309-590 Range on HMM: 1-364/364 Sequence Identity: 31% (118 aa) IGKGRFGEVWRGRWRG----------ENVAVKIFSSRE-------------------------ECSWFREAEIYQTVM---LRHENILGFIAADNKDN-- ||.|.||||..|.||| . ||||.|.|.. | ||||. |.....| |||.||. |..... . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG -------GTWTQLWLVTDYHENGSLFDYLTTHPVDTNTMLNMSLSIATGLAHLHMDIV--GTRGKPAIAHRDLKSKNILVKSNLS--------------C |.|.||..|..|...|||..||. . .....|.|| |...||... .| ||.|.|||||||||||..|. | CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC AIGDLGLAVRHVEKNDSVDIP---------------STHRVGTKRYMAPEVLDESMNDQH----------FDSYKRADVYAFGLILWEIARRCNMGMIYD |.|.||. .. ..... |. . ...||.|.||||||...||... |. ...|||.||..||||. || KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----P EYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHA-------SDVLHNMAKVMKECWYPNPVARLTALRIKKTL .|..||.... || .||| ..|| ...|| ||..| .|... |.| |..|| ..| .|.....|.|.| YYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | BABO.AA | Type2 | 303-590 | 39 | 8.8e-112 | 370.4 | In-house | 1-315 (315) | Show / Hide |
Range on Protein: 303-590 Range on HMM: 1-315/315 Sequence Identity: 39% (125 aa) VQLCHVIGKGRFGEVWRGRWRGE-----NVAVKIFSSREECSWFREAEIYQT-VMLRHENILGFIAADN-KDNGT--WTQLWLVTDYHENGSLFDYLTTH || .|||||||.||...| .. ||||||. .. || | .||.. ....||||| ||.|. . .. | ..||||..|..||| |||. | IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH PVDTNTMLNMSLSIATGLAHLHMDIVGTRG----KPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSV---------DIPSTHRVGTKRYMAPE .| .... | .|.| |||||| .| .. . ||.|||||.||||.|||....|.|.|.|||.| .. . .. | . |||.|||||| TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMR-FCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPE VLDESMNDQH-FDSYKRADVYAFGLILWEIARRCNMGM---IYDEYQLPY-YDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLH-NMAKVMKECWY ||. .| | |. |..|.||.||.|||.. ||. .|||.|. | | |||.|.|. .| .. ||..|. | .. . . .|| VLEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWD PNPVARLTALRIKKTL . |||||. .. . HDAEARLTAQCVQERM |
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Kinase | BABO.AA | Pkinase | 303-590 | 22 | 9.4e-56 | 196.34 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 303-590 Range on HMM: 1-293/293 Sequence Identity: 22% (73 aa) VQLCHVIGKGRFGEVWRGRWRGEN--VAVKIFSSREECSWFREA-----EIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENG----SLFDYLT .. .||.| ||.|......|.. |||||.. |.| ||.... ||. .|.|.||. .. . . ...|..|.|.| .||||.. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS ---THPV--DTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSC----AIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVL .. . .. .. . |. ||...| | |||||. |||...| . |.| ||| . . |...|| .||||||. TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVI DESMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVL-----------------HNM . . ...|....|.||.| . . .|... . ... ......| ...|. ... ... .. R-----GGQYYGPKVDMWSCGCILYEMLCGR----------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC AKVMKECWYPNPVARLTALRIKKT--L ...| |. ..| |.|| |.. . KDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | BABO.AA | MLK | 303-509 | 26 | 5.1e-38 | 129.51 | In-house | 1-229 (291) | Show / Hide |
Range on Protein: 303-509 Range on HMM: 1-229/291 Sequence Identity: 26% (65 aa) VQLCHVIGKGRFGEVWRGRWRGEN-----VAVKIFS-------SREECSWFREAEIYQTVMLRHEN----ILGFIAADNKDNGTWTQLWLVTDYHENGSL |. ..||.| ||.||.||||... ||||.. . .. .| | |... .|.|.| | | .. .... .. .|. | |.||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP---CHFCIVMEYCEGGSL FDYLTTHP---------------VDTNTMLNMSLSIATGLAHLHMDIVGTRGKP-AIAHRDLKSKNILVKS------NLSCAIGDLGLAVRHVEKNDSVD ...| . . .| ..| .| .| |.. ||.. .| .| ||||||.|||. .. . | | |.. ..... YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM------APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR---DWHQMC- IPSTHRVGTKRYMAPEVL---DESMNDQHFDSYKRADVYAFGLILWEI . . || ..|||||. ..... . .||. .|..|||. TNMMSNAGTYAWMAPEVIQQFRCEKYS------EKCDVWSWGVVLWEM |
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Kinase | BABO.AA | TKL-Unique | 305-590 | 29 | 1.4e-32 | 112.31 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 305-590 Range on HMM: 1-290/290 Sequence Identity: 29% (91 aa) LCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECS-WFRE---AEIYQTVMLR-HENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYLT-------- .|| | .|.| .| |||. ||.|.|. |. | ... |. .|. |.||. .... .. . .. .|..| . ||| |.|. FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN ---THPVDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSN-----LSCAIGDLGLAVRHVEKNDSVDIPS-----THRVGTKRYMA .. . . ...| . || |. .|| ....| |.||||||.|.|| .| .. | | ||. |.. . . . |.|. |.|| NNNNCKLNMQQRVKMAIDIAQGMYYLH-----HCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMA PEVLDESMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPV |||| .|| ... . .|||.|| .||||| |. | | || .. | .. ||.... |. || |||.. . . ...|| ..|. PEVL--RMNFCQYS--EKSDVYSFGIVLWEIATRK----ITKTYKKPYQGMDQE--QWCEMVHYM-EENYRPPIPNHC-----PKEYRDLIQQCWHHDPS ARLTALRIKKTL | . | . | QRPSFDEIIHRL |
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Kinase | BABO.AA | S_TKc | 303-595 | 21 | 5.6e-31 | 110.16 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 303-595 Range on HMM: 1-231/231 Sequence Identity: 21% (66 aa) VQLCHVIGKGRFGEVWRGRWRG--ENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHEN--GSLFDYLTTHP---- .. .|||| ||.|...|... . ||.|| . .. || .| . .|.|| .. . . |..|..| .. |.||||. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---VDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHF . . . |. .|...| . | ||||| |||. . |.| ||| . |. .|| ||||||| RFPFPE-HARFYMYQICCALEYCH-------SH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL--------- DSYK--RADVYAFGLILWEIARRCN----MGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVARLTALR .| ..|....| ||.| . .. | |... . . .. |. .| |.|| -GYGKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG--------------------------------------SPEAKDFIRKCLQKDPEKRPTA-E IKK----TLASISV . . . . ALQDEWDIKCHPWF |
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Kinase | BABO.AA | TK | 303-509 | 16 | 4.5e-30 | 97.39 | In-house | 1-387 (486) | Show / Hide |
Range on Protein: 303-509 Range on HMM: 1-387/486 Sequence Identity: 16% (66 aa) VQLCHVIGKGRFG---EVWRGRWRGEN---------------------------VAVKIFS--SREECSWFR------------------EAEIYQTVML ..| ...|.| || ||..|.|||.| ||||. . .. |. |... . .. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG RHENILGFIAADNKDNGTW--------TQLWLVTDYHENGS----LFDYLTTHP---------------------------------------------- .|.||. .... .. . ...|. | ..|. | ||| ... HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY -------------------------------VDTNTMLNMSLSIATGLAHLHMD---IVGTRGKPAI---AHRDLKSKNILVKSNLS-----------CA ... ..| |.. || |...|| | |||| |.|| .|. | DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF--------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK IGDLGLAV-------RHVEKNDSVDIPSTHRVGT-----------------------KRYMAPEVLDESMNDQH---FDSYKRADVYAFGLILWEI |.| ||. | ....| |....|. |.||||.|.. .. ||..|| .||| IADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI |
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Kinase | BABO.AA | TK-Unique | 303-510 | 23 | 1.4e-22 | 74.79 | In-house | 1-233 (294) | Show / Hide |
Range on Protein: 303-510 Range on HMM: 1-233/294 Sequence Identity: 23% (59 aa) VQLCHVIGKGRFGEVWRGRWRG--------ENVAVKIFSSREECS----WFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVTDYHENGSLFDYL . . |||.|.||.|||| .| .|||| .. . ..|..... . .|.||. .. . |. . .. | ..|.| .|| LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKEL-GDHPNIVQCLGCCTKSD---EPWMIIMEYCPCGNLQHYL T-------TH--------------------PVDTNTMLNMSLSIATGLAHLHM--DIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEKND .| |.. .... || |...|. . . |||| ..|.|. ... | |.|.|.| |.|..| RTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI--------VHRDLCARNVLLTEDKVCKICDFGMA-RDVYTNG SVDIPSTHRVGTKRYMAPEVLDESMNDQHFDS-YKRADVYAFGLILWEIA .. . .|.||||.| . | . . ||..|| ..|||. VYSMMCSQGRIPIRWMAPESLKCY----HGMYHTTKSDVWSFGVLMWEIF |
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Kinase | BABO.AA | Pkinase_Tyr | 303-415 | 27 | 6.3e-18 | 61.34 | Pfam | 1-128 (270) | Show / Hide |
Range on Protein: 303-415 Range on HMM: 1-128/270 Sequence Identity: 27% (37 aa) VQLCHVIGKGRFGEVWRGRWR------GENVAVKIF--SSREE----CSWFREAEIYQTVML-RHENILGFIAADN-KDN-GTWTQLWLVTDYHENGSLF ... ...|.| ||||..|.|. . ||||. .. .| . .|||.| | .|.||. .... .. . |...|. | ..|.| ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMK--QLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLL DYLTTH-----PVDTNTMLNMSLSIATGLAHLH ||| .| |... ..|.|.. || |...|. DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLE |
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Kinase | BABO.AA | TyrKc | 303-590 | 26 | 2e-17 | 59.0 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 303-590 Range on HMM: 1-280/280 Sequence Identity: 26% (82 aa) VQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML--RHENILGFIAADNKD--NGTW---TQLWLVTDYHENGSLFDYLTTHP- ..| ...| | ||||..|.|. ..|||| . . |||.| .| .|.||. .... .. | . .|..|. | ..|.| ||| | ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMC--KLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKHRP -VDTNTMLNMSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAVRHVEK-----NDSVDIPST---HR-VGTKRYMAPEVLDE . . ..|.... || | ..|| . |||| |.||..|. . |.| ||. . .. .... ... . . | ||||.. KLCMKDLLSFCWQIACGMEYLHSK--------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-- SMNDQHFDSYKRADVYAFGLILWEIARRCNMGMIYDEYQLPYYDVVQPDPSIEEMKKVVCIEKCRPNIPNRWHASD-----VLHNMAKVMKECWYPNPVA |. | . ||..|| .||| .. | ||....| . | .|. . | . .| || | ..||.|| .| --NYGKFTTK--SDVWSFGVCMWEIFTYG---------QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHEDPED RLTALRIKKTL | | |.. . RPTFSEIHECF |
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Kinase | BABO.AA | CAMK | 308-394 | 16 | 1.6e-16 | 49.06 | In-house | 1-159 (425) | Show / Hide |
Range on Protein: 308-394 Range on HMM: 1-159/425 Sequence Identity: 16% (27 aa) VIGKGRFGEVWRGRWRGEN--------------VAVKIFS-------------------------------SREECSWFREAEIYQTVM-----LRHENI ..|.|.||.| ... . . ||.|| . . . . .|| || ... |.|.|| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LGFIAADN--------KDNG-TWTQ--------LWLVT---DYHENG----SLFDYLTTHP . .. . | . | .. ...|. .| ..| ||||.. |. IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHG |
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GS | BABO.AA | GS | 273-303 | 65 | 1e-15 | 59.45 | SMART | 1-31 (31) | Show / Hide |
Range on Protein: 273-303 Range on HMM: 1-31/31 Sequence Identity: 65% (21 aa) TTIHDIIEM-TTSGSGSAGLPLLVQRSIARQV .|.||..|. .|||||| ||||||||..|||. KTMHDMMEDTCTSGSGS-GLPLLVQRTVARQI |
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Kinase | BABO.AA | Dicty4 | 399-510 | 33 | 2.3e-15 | 47.88 | In-house | 110-211 (277) | Show / Hide |
Range on Protein: 399-510 Range on HMM: 110-211/277 Sequence Identity: 33% (40 aa) TMLN---MSLSIATGLAHLHMDIVGTRGKPAIAHRDLKSKNILVKSNLSCAIGDLGLAV---RHVEKNDSVDIPSTHRVGTKRYMAPEVLDESMNDQHFD ... | ...| |...|| . | | |||||| |.|| |. ..|.||. .| ...| . . .|| .|||||. . | .. LIKRAMRMAFDAARGMNWLHCCN------PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA----CGTPCWMAPEVMMH----QPYN SYKRADVYAFGLILWEIA . |||| ||..||||. E--KADVYSFGIVLWEIL |
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TGF_beta_GS | BABO.AA | TGF_beta_GS | 273-301 | 66 | 7.1e-14 | 48.67 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 273-301 Range on HMM: 1-29/29 Sequence Identity: 66% (20 aa) TTIHDIIE-MTTSGSGSAGLPLLVQRSIAR .|..|..| ..|||||| ||||||||.||| KTMQDMMEDFCTSGSGS-GLPLLVQRTIAR |
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Kinase | BABO.AA | CAMK | 427-482 | 24 | 9.6e-11 | 30.11 | In-house | 200-292 (425) | Show / Hide |
Range on Protein: 427-482 Range on HMM: 200-292/425 Sequence Identity: 24% (23 aa) IAHRDLKSKNILVKSN-----------------LSCAIGDLGLAVRHVEKNDSV-------------------DIPSTHRVGTKRYMA-PEVL |.||||| |||. .| | | |.| . ..... . . . ..|| ||| |||| IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVL |
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Kinase | BABO.AA | Dicty4 | 303-335 | 48 | 3.2e-10 | 30.48 | In-house | 1-33 (277) | Show / Hide |
Range on Protein: 303-335 Range on HMM: 1-33/277 Sequence Identity: 48% (16 aa) VQLCHVIGKGRFGEVWRGRWRGENVAVKIFSSR . |||| |||| .|.||| ||||.. .. INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNH |
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Kinase | BABO.AA | Pkinase_Tyr | 429-509 | 32 | 2.1e-07 | 25.7 | Pfam | 134-207 (270) | Show / Hide |
Range on Protein: 429-509 Range on HMM: 134-207/270 Sequence Identity: 32% (27 aa) HRDLKSKNILVKSNLSCAIGDLGLAVRHVEKNDSVD-IPSTHRVGTKRYMAPEVLDESMNDQHFDSYKRADVYAFGLILWEI |||| .|.||..|. . |.| ||| . ||. ... . ||||.. .. | . ||..|| .||| HRDLAARNCLVTENNVVKICDFGLARDI--YNDDYYYRKRGGGKLPIKWMAPECINYGK----FTTK--SDVWSFGVLMWEI |
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Kinase | BABO.AA | TK | 565-590 | 26 | 0.001275 | 7.16 | In-house | 461-486 (486) | Show / Hide |
Range on Protein: 565-590 Range on HMM: 461-486/486 Sequence Identity: 26% (7 aa) MAKVMKECWYPNPVARLTALRIKKTL .. .|..|| ..| | | ... | YYDLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | BABO.AA | Pkinase_Tyr | 565-590 | 34 | 0.094744 | 6.55 | Pfam | 245-270 (270) | Show / Hide |
Range on Protein: 565-590 Range on HMM: 245-270/270 Sequence Identity: 34% (9 aa) MAKVMKECWYPNPVARLTALRIKKTL . ..||.|| ..| | | | | IYDLMKQCWHYDPEDRPTFSEIHEQL |
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Kinase | BABO.AA | TK-Unique | 563-590 | 39 | 0.136088 | 1.41 | In-house | 267-294 (294) | Show / Hide |
Range on Protein: 563-590 Range on HMM: 267-294/294 Sequence Identity: 39% (11 aa) HNMAKVMKECWYPNPVARLTALRIKKTL | | ..||.|| .| | . ||. | HEMYNLMKSCWQWEPEERPSFRQIKHRL |
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Kinase | BABO.AA | Dicty4 | 543-580 | 28 | 0.297862 | 0.13 | In-house | 231-263 (277) | Show / Hide |
Range on Protein: 543-580 Range on HMM: 231-263/277 Sequence Identity: 28% (11 aa) VCIEKCRPNIPNRWHASDVLHNMAKVMKECWYPNPVAR || .| || ||. ... . .. ...|| ..| | VCNKKLRPPIPD-----WCPPSWKHLIQWCWDHDPQHR |