Gene ADCK4 (Mouse)

ADCK4

Species: Mouse
Alias: 0610012P18Rik, ADCK4
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP
Annotation:

Classification

Group: Atypical
Family: ABC1
Subfamily: ABC1-A

Sequence

Name Sequence Type Origin Length Description Download
ADCK4.kin_dom Protein Kinase Domain None 303 None Fasta, JSON
ADCK4.AA Protein Sugen 533 None Fasta, JSON
ADCK4.NA RNA Sugen 2190 None Fasta, JSON

Protein domain

Protein domains of ADCK4.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase ADCK4.AA ABC1-A 211-407 58 5.1e-155 521.3 In-house 1-216 (216) Show / Hide 
Range on Protein: 211-407
Range on HMM: 1-216/216
Sequence Identity: 58% (126 aa)

LEEVPFAAASIGQVHQGLLKDGTEVAVKIQYPGVAQSIQSDVENLLALLKMSVGLPEGLFAEQSLQTLQQELAWECDYCREAACAQTFRKLLADDPFFRV
.||.|||.||||||||..||||.||||||||||||.||.||. ||.....||  .|.|.|...... ...||.||||| |||.|.| || ||.|.|||.|
FEEMPFACASIGQVHQAVLKDGREVAVKIQYPGVAESIDSDINNLMMVMNMSGMFPKGMFLDHFIDYARRELHWECDYQREARCMQKFRQLLKDWPFFYV

PAVVQELCTTRVLGMELAGGIPLDQCQGLSQDIRNQICFQLLRLCLR---------------ELFEFRFMQTDPNWANFLYDAS----SHQVTLLDFGAS
|.|. |.||.|||.|||..| |.||||||||.|||.||....|||||               |.||.||||||||||||.||..    .|.|.|||||||
PHVIDEYCTDRVLTMELMYGFPIDQCQGLSQEIRNYICYNIMRLCLREVEYIFLSTFIIIDFEIFEWRFMQTDPNWANFFYDKHPKTGQHKVELLDFGAS

RAFGTEFTDHYIEVVK
|..|..|||||....|
REYGKDFTDHYMQIIK
Kinase ADCK4.AA ABC1 198-314 41 1.5e-57 197.49 In-house 1-123 (123) Show / Hide 
Range on Protein: 198-314
Range on HMM: 1-123/123
Sequence Identity: 41% (51 aa)

EELGKDWQDKVASLEEVPFAAASIGQVHQGLLKDGTEVAVKIQYPGVAQSIQSDVENLLALLKMSVGLPEG-----LFAEQSLQTLQQELAWECDYCREA
..||  | |   ...| |||||||.|||.. ||||..||||.|.|||...|..|. |.....||.  ...|     .| .. .. .|.||.||||. .||
QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKDGQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNEA

ACAQTFRKLLA--DDPFFRVPAVV
..|. .| |..  ..|||.|| ..
RNAEKCRQLFKKFHWPFFYVPRIH
Kinase ADCK4.AA ABC1 198-314 36 4.5e-43 147.1 Pfam 1-126 (126) Show / Hide 
Range on Protein: 198-314
Range on HMM: 1-126/126
Sequence Identity: 36% (46 aa)

EELGKDWQDKVASLEEVPFAAASIGQVHQGLLKD-GTEVAVKIQYPGVAQSIQSDVENLLALLKMSVGLPEG-----LFAEQSLQTLQQELAWECDYCRE
||||..| .. .. .|.|.|||||.|||.. ||| | |||||.|.|||.... .|..|.  ..|    .. |     .. .. .......|.||.|| ||
EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE

AACAQTFRKLLADD---PFFRVPAVV
|. .  ||......   |...|| |.
AKNMERFRENFRHWHRQPWVYVPKVY
Kinase ADCK4.AA ABC1-B 212-314 27 4.9e-12 40.76 In-house 14-125 (125) Show / Hide 
Range on Protein: 212-314
Range on HMM: 14-125/125
Sequence Identity: 27% (32 aa)

EEVPFAAASIGQVHQGLLKDGTEVAVKIQYPGVAQSIQSDVENLLALLKMSVGLPEGLFA----------EQSLQTLQQELAWECDYCREAACAQTFRKL
.. | ||||. |||   |.||..||||.|.| .  ..  |. ... |.   | . . .|.             .. .|. |. | |   ||  |   | .
DQKPIAAASLAQVHRAKLHDGETVAVKVQHPWLRKQFHYDM-MMMELF---VKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYNEARNAEKCRQM

LA---DDPFFRVPAVV
..   . .| .|| . 
FKKFKHFDFLYVPRIH