Gene ALK7 (Mouse)
ALK7
Sequence
Protein domains of ALK7.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Activin_recp | ALK7.AA | Activin_recp | 26-100 | 24 | 9.6e-27 | 90.42 | Pfam | 1-121 (121) | Show / Hide |
Range on Protein: 26-100 Range on HMM: 1-121/121 Sequence Identity: 24% (30 aa) LKCV-CLL--------CD--SSN-----FTCQT----------EGACWASVMLTNG---KEQVIK----SCVSLPELNAQ---VFCHS-----SNN---V |||. | |. .| .||.| .|.|..|...... .||... .|.||.|. | |.| |.. LKCYFCNGYWEYDYQICHENENNFEIPVHTCETHPDKMCFYCYDGQCYVSWEYNDDEEDTEQHQRMHMYGCWSLNENCPQCHPFMCKSYKHTHSPPHRHG TKTEC-CF-TDFCNNITLHLP ...|| | ||.||.. ..| HNHECWCCETDYCNRNLTPPP |
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Kinase | ALK7.AA | Type1 | 195-482 | 71 | 1.2e-274 | 753.76 | In-house | 1-290 (290) | Show / Hide |
Range on Protein: 195-482 Range on HMM: 1-290/290 Sequence Identity: 71% (207 aa) IVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMVK |...|..||||.||||.|.|.||.||||||.||||||||||.|||||||.||||||||||||.||||.||||||...|||.|||||||||..... .|.. IQMIECIGKGRYGEVWRGKWRGENVAVKIFFSRDERSWFRETEIYQTVMMRHENILGFIAADMKDNGSWTQLWLITDYHEHGSLYDYLNRHTLDTQQMLR LALSIASGLAHLHMEIVGTQ--GKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNLSIFESFKRADIY ||.|.|.|||||||||.||| |||||||||||||||.|||...|.||||||||.|.. ...|||.|||.||||||||||.||.||| |||.|.|||| LAYSCACGLAHLHMEIFGTQEFGKPAIAHRDIKSKNIMVKKNGQCCIADLGLAVRHQQDTDQIDIGQNPRVGTKRYMAPEVLDETMNMNCFESYKMADIY SVGLVYWEIARRCSVGGVVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQSCEALRVMGRIMRECWYANGAARLTALRVKKTI |.|||.|||||||.|||.||.|||||||.||.|||.|.||||||..||||| ||.|||....|.|...|.||||.|..||.||||.|||. SFGLVMWEIARRCEVGGIVEDYQLPYYDWVPNDPSFEDMRKVVCVRKLRPNIPNRWQSHPCMRHMAKLMKECWYQNPHARHTALRIKKTL |
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Kinase | ALK7.AA | STKR | 195-482 | 60 | 7.89999999999e-219 | 713.48 | In-house | 1-312 (312) | Show / Hide |
Range on Protein: 195-482 Range on HMM: 1-312/312 Sequence Identity: 60% (188 aa) IVLQEIVGKGRFGEVWHGRWCG----EDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDN-GTWTQLWLVSEYHEQGSLYDYLNRNIVTV |.|.|..||||.||||.|.|.| |.||||||.||||.|||||.|||||.|.||||||.|||||.|.. |.|||.||..||||.|||.|||.|..... IQLIECIGKGRYGEVWKGKWRGNGEKETVAVKIFPSRDEQSWFRETEIYQTPMMRHENILQFIAADMKHTEGSWTQYWLITEYHENGSLCDYLKRHTIDW AGMVKLALSIASGLAHLHMEIV--GTQ--GKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIP-------QNPKVGTKRYMAPEMLDDTM .|...|.|.|.|||||||||. ||| .|||||||||||||||||.. ||.|||.|||..||. |.|||. ||..||||||||||.||..| HEMCRMAHSMACGLAHLHMEIWGWGTQQHHKPAIAHRDIKSKNILVKNDGTCCIADFGLAMRHDPDTNQIDIHNTMQDNAQNTQVGTKRYMAPEVLDGAM NLSIFES-FKRADIYSVGLVYWEIARRCSVGG------VVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQ-SCEALRVMGRIMRECWYANGA |. ||| |||.|.|..|||.|||||||..|| |.|||.|.||.||..||.|.|.|||| ...|||.||.|. ...|.|.| .|.|||..... NFQCFESAFKRMDMYAMGLVMWEIARRCTDGGPDLVDQIVPEYQMPFYDWVPNHPSFEDMQKVVCRKRQRPNIPNRWKCNHPAMRSMCKTMEECWDHDPE ARLTALRVKKTI ||||||.||||. ARLTALCVKKTM |
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Kinase | ALK7.AA | Type2 | 195-482 | 39 | 2.4e-115 | 382.34 | In-house | 1-315 (315) | Show / Hide |
Range on Protein: 195-482 Range on HMM: 1-315/315 Sequence Identity: 39% (125 aa) IVLQEIVGKGRFGEVWHGRWCGE-----DVAVKIFSSRDERSWFREAEIYQT-VMLRHENILGFIAADN-KDNGT--WTQLWLVSEYHEQGSLYDYLNRN | | |..||||||.|| ..| .. .||||||. .| || | .||.. ....||||| ||.|. . .. | ..|||.|.|. |||.||| .. IQLMELIGKGRFGCVWKAQWHNNNGEKRTVAVKIFPEQDKQSWQNEKDIYSLPYHMWHENILQFICAEKRRVHMGDGWMEYWLVTEFHHKGSLCDYLKQH IVTVAGMVKLALSIASGLAHLHMEIV-GTQ---GKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNT----IDIPQNPK----VGTKRYMAPEM ... . ..|.|.| |||||| || ..| ||.||||||||||.||| ||.|||.|||.. . .. |. .. |||.||||||. TIDWHECCRMAMSMARGLAHLHEEIWQWCQTDHHKPPIAHRDIKSKNVLVKNDMTCCIADFGLAMRFCPGKQPYKWEPTMPGDTHNIGQVGTRRYMAPEV LDDTMNLS-IFESFKRADIYSVGLVYWEIARRCSVGG---VVEEYQLPYYDMVPSD-PSIEEMRKVVCDQKLRPNLPNQWQSCEALR-VMGRIMRECWYA |. ..|. ..||..|.|. |||.||.. ||.. . | |||.|. | . ||.|.|. .| . ||..|. |. ... . . .|| . LEGAVNFQDCRDAFKQMDMYAMGLVLWEMVSRCTDHYPDDEVPEYQMPFEEEVGQHDPSFEDMQELVVRKRKRPQWPDHWKCHPGMQRMLCETIEDCWDH NGAARLTALRVKKTI |||||. |. . DAEARLTAQCVQERM |
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Kinase | ALK7.AA | TKL | 201-482 | 30 | 3.3e-105 | 355.82 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 201-482 Range on HMM: 1-364/364 Sequence Identity: 30% (116 aa) VGKGRFGEVWHGRWCG----------EDVAVKIFSSRD-------------------------ERSWFREAEIYQTVM---LRHENILGFIAADNKDN-- .|.|.||||..|.| | .|||||.|.|.. | ||||. |.....| |||.||. |..... . IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG -------GTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMVKLALSIASGLAHLHMEIV--GTQGKPAIAHRDIKSKNILVKKCDT--------------C |.|.||..| ||.. |||..||. ....||.||.|...||... .| ||.|.|||.|||||||.. | | CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT--KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC AIADLGLAVKHDSIMNTIDIP---------------QNPKVGTKRYMAPEMLDDTMNLSI----------FESFKRADIYSVGLVYWEIARRCSVGGVVE |.|.||. .. .| |. ....||.|.||||.|...||.. || ....|.|| |.| |||. || KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----P EYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQS-------CEALRVMGRIMRECWYANGAARLTALRVKKTI .|..||..|...|| .||| ..||| .||| .|..||. ... | ..| .|| .. .|.......|.. YYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL |
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Kinase | ALK7.AA | Pkinase | 195-482 | 20 | 4e-45 | 160.64 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 195-482 Range on HMM: 1-293/293 Sequence Identity: 20% (66 aa) IVLQEIVGKGRFGEVWHGRWCGED--VAVKIFSSRDERSWFREA-----EIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQG----SLYDYLN ... ...|.| ||.|..... |. |||||.. |.|.||.... ||. .|.|.||. .. . . ...| ||.| | .|.||. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED----KDHIYMVMEYCEGGLYVMDLFDYIS ---RNIV--TVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCDTC----AIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEML .. . . . .. |..||...| . | |||.|. |||... ... |.| ||| ..| . . . .|| .||||| . TWRHGCFYFSEWECKFYMYQILRGLEYCHSM--------GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---Y-NNS-MTTFCGTPWYMAPEVI DDTMNLSIFESFKRADIYSVGLVYWEIARRCSVGGVVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQSCEAL-----------------RVM . . ...|..|.|.. .| . . .|... . ... ......| . .|. . ...|. . . R-----GGQYYGPKVDMWSCGCILYEMLCGR----------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC GRIMRECWYANGAARLTALRVKKT--I ... |. . . |.|| ... . KDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | ALK7.AA | MLK | 195-401 | 26 | 2.6e-36 | 123.49 | In-house | 1-229 (291) | Show / Hide |
Range on Protein: 195-401 Range on HMM: 1-229/291 Sequence Identity: 26% (67 aa) IVLQEIVGKGRFGEVWHGRWCGED-----VAVKIFS-------SRDERSWFREAEIYQTVMLRHEN----ILGFIAADNKDNGTWTQLWLVSEYHEQGSL | ..|..|.| ||.|| ||| ..| ||||.. . .. .| | |... .|.|.| | | .. .... .. .|.|| | ||| IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP---CHFCIVMEYCEGGSL YDYLNRN---------------IVTVAGMVKLALSIASGLAHLHMEIVGTQGKP-AIAHRDIKSKNILVK------KCDTCAIADLGLAV-KHDS---IM |..|. . ..... ... || .|.|.. ||.. .| .| |||.||.|||. . .|. |.| |.. .|.. | YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSM------APKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMM NTIDIPQNPKVGTKRYMAPEML----DDTMNLSIFESFKRADIYSVGLVYWEI ... || ..||||.. .. . . .|..| |.| ||. SNA--------GTYAWMAPEVIQQFRCEKYS-------EKCDVWSWGVVLWEM |
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Kinase | ALK7.AA | TKL-Unique | 197-405 | 28 | 2e-24 | 83.18 | In-house | 1-225 (290) | Show / Hide |
Range on Protein: 197-405 Range on HMM: 1-225/290 Sequence Identity: 28% (67 aa) LQEIVGKGRFGEVWHGRWCGEDVAVKIFS-SRDERSWFRE---AEIYQTVMLR-HENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLN-------- . .| | .|.| .| | |..||.|.|. | .. ... |. .|. |.||. .... .. . .. .|.|| . |||||.|. FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN --RNIV-TVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKC-----DTCAIADLGLAVKHDSIMNTIDIPQN-----PKVGTKRYMA .|. . . .||.|. ||.|. .|| .. .| |.|||.||.|.|| |.| ||. ..|.... . . ..|. |.|| NNNNCKLNMQQRVKMAIDIAQGMYYLHHCE-----PP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMA PEMLDDTMNLSIFESFKRADIYSVGLVYWEIARRC ||.| . . . .|.|| | | |||| |. PEVLRMNF----CQYSEKSDVYSFGIVLWEIATRK |
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Kinase | ALK7.AA | STE | 195-402 | 20 | 1.6e-21 | 72.83 | In-house | 1-262 (359) | Show / Hide |
Range on Protein: 195-402 Range on HMM: 1-262/359 Sequence Identity: 20% (58 aa) IVLQEIVGKGRFGEVWHGRWC-----------------GEDVAVKIFSSRDERS---------------WFRE---AEIYQTVMLR--HENILGFIAADN ..|..||| ||.| .. || .|.|. . ..... .. || .. |.|| .. . WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF KD---NGTWTQLWLVSEYHEQGSLYDYLNRNIVT---------------VAGMVKLALSIASG-LAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCDTCA |. .. ..||.. || . ||| | .... . . . .| | |..|| | |||||. |||. . KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--------IIHRDIKPANILL-----VK IADLGLAVKHDSIMN------------TIDIPQNPKVGTKRYMAPEMLDD-TMNLSIFESFK----RADIYSVGLVYWEIA ..| |.. . ...| |.. | ||| .||||... . . . | ..||.|.|.. .| | LCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-R----DKGYDTKCDIWSLGCTIIEMA |
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Kinase | ALK7.AA | TK | 195-350 | 15 | 4.9e-21 | 66.57 | In-house | 1-311 (486) | Show / Hide |
Range on Protein: 195-350 Range on HMM: 1-311/486 Sequence Identity: 15% (49 aa) IVLQEIVGKGRFG---EVWHGRWCG---------------------------EDVAVKIFS---SRDERSWFR-----------------EAEIYQTVML |.| . |.| || ||. |.| | ..||||. . ... | |... . .. ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG RHENILGFIAADNKDNGTW--------TQLWLVSEYHEQGS----LYDYLNRN----------------------------------------------- .|.||. .... .. . ...| || . |. | ||| .. HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY ------------------------------IVTVAGMVKLALSIASGLAHLHME---IVGTQGKPAI---AHRDIKSKNILVKKCDT-----------CA ..|.. .. .. ||.|...|| | |||. |.|| . .. | DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF--------IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCK IADLG--------LAVKHDS ||| | || ...| IADFGLSRQGSGVLARDIYS |
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Kinase | ALK7.AA | S_TKc | 195-487 | 19 | 1e-20 | 76.05 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 195-487 Range on HMM: 1-231/231 Sequence Identity: 19% (59 aa) IVLQEIVGKGRFGEVWHGRWCG--EDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQ--GSLYDYLNRNI---- . ...||| ||.|. .|. . . ||.|| . .. || .| . .|.|| .. . . |..| || .. |.|.||. .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---VTVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNLSIF . ... |...|...| . | |||.| |||. . . |.| ||| . . .|| |||||.| RFPFPE-HARFYMYQICCALEYCH-------SH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----------TTFCGTPWYMAPEVL--------- ESFK--RADIYSVGLVYWEIARRCSVGGVVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQSCEALRVMGRIMRECWYANGAARLTALRVKK- .. ..|..|.| . .| . .. ..|. . .. . ..| |. . . |.|| . . -GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG------------------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQD ---TISQLCV . . EWDIKCHPWF |
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Kinase | ALK7.AA | CAMK | 200-374 | 18 | 3.7e-19 | 57.73 | In-house | 1-292 (425) | Show / Hide |
Range on Protein: 200-374 Range on HMM: 1-292/425 Sequence Identity: 18% (56 aa) IVGKGRFGEVWHGRWCGED--------------VAVKIFS-------------------------------SRDERSWFREAEIYQTVM-----LRHENI . |.|.||.| .. ||.|| . .|... .|| || ... |.|.|| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LGFIAADN--------KDNG-TWTQ--------LWLVS---EYHEQG----SLYDYLNRN-----------IVTVAGMV------KLALSIASGLAHLHM . .. . | . | .. ...| || . | |.||. .. || | . .. |.|.....| IKLYEVYEDPHYFKNTND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHS EIVGTQGKPAIAHRDIKSKNILVKKCD-----------------TCAIADLGLAVKHDSIMNTI-------------------DIPQNPKVGTKRYMA-P |.|||.| |||. . . . |.| |.| | |. | . . . .|| ||| | H--------NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAP EML |.| EVL |
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TGF_beta_GS | ALK7.AA | TGF_beta_GS | 165-193 | 72 | 7.4e-17 | 58.46 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 165-193 Range on HMM: 1-29/29 Sequence Identity: 72% (21 aa) KTLKDLIYDATASGSGSGLPLLVQRTIAR ||..|...| . ||||||||||||||||| KTMQDMMEDFCTSGSGSGLPLLVQRTIAR |
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Kinase | ALK7.AA | Pkinase_Tyr | 195-307 | 27 | 2.2e-16 | 56.12 | Pfam | 1-128 (270) | Show / Hide |
Range on Protein: 195-307 Range on HMM: 1-128/270 Sequence Identity: 27% (36 aa) IVLQEIVGKGRFGEVWHGRWC------GEDVAVKIF--SSRDE----RSWFREAEIYQTVML-RHENILGFIAADN-KDN-GTWTQLWLVSEYHEQGSLY |.. . |.| ||||..|.| . .||||. .. .| .. .|||.| | .|.||. .... .. . |...| || . |.|. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMK--QLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLL DYLNRN-----IVTVAGMVKLALSIASGLAHLH ||| .. .|. ... .. ||.|...|. DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLE |
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GS | ALK7.AA | GS | 165-195 | 67 | 7e-16 | 60.0 | SMART | 1-31 (31) | Show / Hide |
Range on Protein: 165-195 Range on HMM: 1-31/31 Sequence Identity: 67% (21 aa) KTLKDLIYDATASGSGSGLPLLVQRTIARTI ||..|...| . ||||||||||||||.||.| KTMHDMMEDTCTSGSGSGLPLLVQRTVARQI |
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Kinase | ALK7.AA | TyrKc | 195-482 | 25 | 9e-15 | 16.18 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 195-482 Range on HMM: 1-280/280 Sequence Identity: 25% (79 aa) IVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVML--RHENILGFIAADNKD--NGTW---TQLWLVSEYHEQGSLYDYLNRNI- |.| .. | | ||||..|.| ..|||| . .. |||.| .| .|.||. .... .. | . .|..| || . |.| ||| .. ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMC--KLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKHRP -VTVAGMVKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSI----MNTIDIPQ----NPK-VGTKRYMAPEMLDD .... ... .. ||.| ..|| . |||. |.||.. |. |.| ||. .... .. . . . | . | |||| . KLCMKDLLSFCWQIACGMEYLHSK--------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-- TMNLSIFESFKRADIYSVGLVYWEIARRCSVGGVVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLPNQWQSCE-----ALRVMGRIMRECWYANGAA | ..| . |..| | . ||| .. | ||..|. . | .|... | . . .| || . . | .||..|| .. . --NYGKFTTK--SDVWSFGVCMWEIFTYG---------QQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY---PMSFVCCPDEMYQIMKQCWHEDPED RLTALRVKKTI | | ... . RPTFSEIHECF |
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Kinase | ALK7.AA | Dicty4-Unclassified | 293-445 | 32 | 1.1e-11 | 36.21 | In-house | 112-231 (263) | Show / Hide |
Range on Protein: 293-445 Range on HMM: 112-231/263 Sequence Identity: 32% (50 aa) VKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCDTCAIADLGLAVKHDSIMNTIDIPQNPKVGTKRYMAPEMLDDTMNLSIFESF-KRADI .| |..|| |..||| . |||||| |||. | |||.|.. | | | || . .|| | ||. ..|. IKYAFDIAQGMQHLHTR--------NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTI-----AGTPKWESPECL-------MHESYNQKSDV YSVGLVYWEIARRCSVGGVVEEYQLPYYDMVPSDPSIEEMRKVVCDQKLRPNLP || ... .| | .| || . .|| .. ||| |||| .| YSYAMMLYELA-------TGDE---PYQEI----QSIMNAARSVCDKKLRPKIP |
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Kinase | ALK7.AA | Dicty4-Unclassified | 196-226 | 51 | 7e-08 | 23.04 | In-house | 3-32 (263) | Show / Hide |
Range on Protein: 196-226 Range on HMM: 3-32/263 Sequence Identity: 51% (16 aa) VLQEIVGKGRFGEVWHGRWCGEDVAVKIFSS ..|.| ||| | .| | | | |||||.| . IDQFI-GKGHFSKVHKGNWKGKDVAVKKFNE |
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Kinase | ALK7.AA | TK | 459-482 | 20 | 0.038269 | 2.12 | In-house | 463-486 (486) | Show / Hide |
Range on Protein: 459-482 Range on HMM: 463-486/486 Sequence Identity: 20% (5 aa) RIMRECWYANGAARLTALRVKKTI ..|..|| .. . | | ... . DLMQQCWHYDPEDRPTFSQLHEQL |
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Kinase | ALK7.AA | Pkinase_Tyr | 321-345 | 44 | 3.015847 | 1.46 | Pfam | 134-158 (270) | Show / Hide |
Range on Protein: 321-345 Range on HMM: 134-158/270 Sequence Identity: 44% (11 aa) HRDIKSKNILVKKCDTCAIADLGLA |||. .|.||.. .. |.| ||| HRDLAARNCLVTENNVVKICDFGLA |